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1BYU
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BU of 1byu by Molmil
CANINE GDP-RAN
Descriptor: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PROTEIN (GTP-BINDING PROTEIN RAN)
Authors:Stewart, M, Kent, H.M, Mccoy, A.J.
Deposit date:1998-10-18
Release date:1998-12-02
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:The structure of the Q69L mutant of GDP-Ran shows a major conformational change in the switch II loop that accounts for its failure to bind nuclear transport factor 2 (NTF2).
J.Mol.Biol., 284, 1998
5BXQ
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BU of 5bxq by Molmil
Structure of the NTF2:RanGDP complex
Descriptor: GTP-binding nuclear protein Ran, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Stewart, M.
Deposit date:2015-06-09
Release date:2015-07-01
Last modified:2019-10-09
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis for molecular recognition between nuclear transport factor 2 (NTF2) and the GDP-bound form of the Ras-family GTPase Ran.
J.Mol.Biol., 277, 1998
1EQ6
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BU of 1eq6 by Molmil
1.9 ANGSTROM RESOLUTION CRYSTAL STRUCTURE OF THE SACCHAROMYCES CEREVISIAE RAN-BINDING PROTEIN MOG1P
Descriptor: MOG1P
Authors:Stewart, M, Baker, R.P.
Deposit date:2000-04-03
Release date:2000-05-27
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:1.9 A resolution crystal structure of the Saccharomyces cerevisiae Ran-binding protein Mog1p.
J.Mol.Biol., 299, 2000
3RAN
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BU of 3ran by Molmil
CANINE GDP-RAN Q69L MUTANT
Descriptor: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PROTEIN (GTP-BINDING NUCLEAR PROTEIN RAN)
Authors:Stewart, M, Kent, H.M, Mccoy, A.J.
Deposit date:1998-10-19
Release date:1998-12-02
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:The structure of the Q69L mutant of GDP-Ran shows a major conformational change in the switch II loop that accounts for its failure to bind nuclear transport factor 2 (NTF2).
J.Mol.Biol., 284, 1998
4U5L
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BU of 4u5l by Molmil
IMPORTIN-ALPHA MINOR NLS SITE INHIBITOR
Descriptor: Importin subunit alpha-1, N~2~-[4-(pyridin-3-yl)benzyl]-L-lysinamide
Authors:Stewart, M, Valkov, E, Holvey, R.S.
Deposit date:2014-07-25
Release date:2015-05-13
Last modified:2015-07-08
Method:X-RAY DIFFRACTION (2.53 Å)
Cite:Selective Targeting of the TPX2 Site of Importin-alpha Using Fragment-Based Ligand Design.
Chemmedchem, 10, 2015
4U5V
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BU of 4u5v by Molmil
IMPORTIN-ALPHA MINOR NLS SITE INHIBITOR
Descriptor: Importin subunit alpha-1, N~2~-{[5-(pyridin-3-yl)thiophen-2-yl]methyl}-L-lysinamide
Authors:Stewart, M, Valkov, E, Holvey, R.S.
Deposit date:2014-07-25
Release date:2015-05-13
Last modified:2015-07-08
Method:X-RAY DIFFRACTION (1.968 Å)
Cite:Selective Targeting of the TPX2 Site of Importin-alpha Using Fragment-Based Ligand Design.
Chemmedchem, 10, 2015
4U5N
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BU of 4u5n by Molmil
IMPORTIN-ALPHA MINOR NLS SITE INHIBITOR
Descriptor: Importin subunit alpha-1, N~2~-[4-(pyridin-3-yl)benzyl]-L-lysyl-N-[(1R,2S,3R)-1-{[(2R)-1-amino-1-oxo-3-phenylpropan-2-yl]amino}-1,3-dihydroxybutan-2-yl]glycinamide
Authors:Stewart, M, Valkov, E, Holvey, R.S.
Deposit date:2014-07-25
Release date:2015-05-13
Last modified:2015-07-08
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:Selective Targeting of the TPX2 Site of Importin-alpha Using Fragment-Based Ligand Design.
Chemmedchem, 10, 2015
4U5S
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BU of 4u5s by Molmil
IMPORTIN-ALPHA MINOR NLS SITE INHIBITOR
Descriptor: Importin subunit alpha-1, N-[(2S)-2-[(N~2~-acetyl-D-lysyl)amino]-3-(pyridin-3-ylmethoxy)propyl]-L-allothreonyl-D-phenylalaninamide
Authors:Stewart, M, Valkov, E, Holvey, R.S.
Deposit date:2014-07-25
Release date:2015-05-13
Last modified:2017-06-21
Method:X-RAY DIFFRACTION (2.12 Å)
Cite:Selective Targeting of the TPX2 Site of Importin-alpha Using Fragment-Based Ligand Design.
Chemmedchem, 10, 2015
4U54
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BU of 4u54 by Molmil
IMPORTIN-ALPHA MINOR NLS SITE INHIBITOR
Descriptor: Importin subunit alpha-1, N-methyl-1-[3-(pyridin-3-yl)phenyl]methanamine
Authors:Stewart, M, Valkov, E, Holvey, R.S.
Deposit date:2014-07-24
Release date:2015-05-13
Last modified:2015-07-08
Method:X-RAY DIFFRACTION (2.41 Å)
Cite:Selective Targeting of the TPX2 Site of Importin-alpha Using Fragment-Based Ligand Design.
Chemmedchem, 10, 2015
4U58
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BU of 4u58 by Molmil
IMPORTIN-ALPHA MINOR NLS SITE INHIBITOR
Descriptor: Importin subunit alpha-1, N~2~-[4-(pyridin-3-yl)benzoyl]-L-lysinamide
Authors:Stewart, M, Valkov, E, Holvey, R.S.
Deposit date:2014-07-24
Release date:2015-05-13
Last modified:2015-07-08
Method:X-RAY DIFFRACTION (2.56 Å)
Cite:Selective Targeting of the TPX2 Site of Importin-alpha Using Fragment-Based Ligand Design.
Chemmedchem, 10, 2015
4U5O
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BU of 4u5o by Molmil
IMPORTIN-ALPHA MINOR NLS SITE INHIBITOR
Descriptor: Importin subunit alpha-1, N~2~-[4-(pyridin-3-yl)benzyl]-D-lysinamide
Authors:Stewart, M, Valkov, E, Holvey, R.S.
Deposit date:2014-07-25
Release date:2015-05-13
Last modified:2015-07-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:Selective Targeting of the TPX2 Site of Importin-alpha Using Fragment-Based Ligand Design.
Chemmedchem, 10, 2015
4U5U
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BU of 4u5u by Molmil
IMPORTIN-ALPHA MINOR NLS SITE INHIBITOR
Descriptor: Importin subunit alpha-1, N~2~-[3-(pyridin-3-yl)benzyl]-L-lysinamide
Authors:Stewart, M, Valkov, E, Holvey, R.S.
Deposit date:2014-07-25
Release date:2015-05-13
Last modified:2015-07-08
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Selective Targeting of the TPX2 Site of Importin-alpha Using Fragment-Based Ligand Design.
Chemmedchem, 10, 2015
1WA5
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BU of 1wa5 by Molmil
Structure of the Cse1:Imp-alpha:RanGTP complex
Descriptor: GTP-binding nuclear protein Ran, GUANOSINE-5'-TRIPHOSPHATE, Importin alpha re-exporter, ...
Authors:Stewart, M.
Deposit date:2004-10-23
Release date:2004-12-13
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for the assembly of a nuclear export complex.
Nature, 432, 2004
5UBP
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BU of 5ubp by Molmil
TREX2 M-region
Descriptor: 26S proteasome complex subunit SEM1, Leucine permease transcriptional regulator, Nuclear mRNA export protein THP1
Authors:Stewart, M, Gordon, J.
Deposit date:2016-12-21
Release date:2017-04-05
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of the Sac3 RNA-binding M-region in the Saccharomyces cerevisiae TREX-2 complex.
Nucleic Acids Res., 45, 2017
5L2L
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BU of 5l2l by Molmil
Nab2 Zn fingers 5-7 bound to A11G RNA
Descriptor: Nab2p, RNA (5'-R(*AP*AP*AP*AP*AP*AP*AP*AP*AP*G)-3'), ZINC ION
Authors:Stewart, M, Aibara, S.
Deposit date:2016-08-02
Release date:2016-12-21
Last modified:2017-06-14
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structural basis for the dimerization of Nab2 generated by RNA binding provides insight into its contribution to both poly(A) tail length determination and transcript compaction in Saccharomyces cerevisiae.
Nucleic Acids Res., 45, 2017
5L3T
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BU of 5l3t by Molmil
Structure of the Saccharomyces cerevisiae TREX-2 complex
Descriptor: 26S proteasome complex subunit SEM1, Nuclear mRNA export protein SAC3, Nuclear mRNA export protein THP1, ...
Authors:Stewart, M, Aibara, S.
Deposit date:2016-05-24
Release date:2016-07-27
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (4.927 Å)
Cite:The Sac3 TPR-like region in the Saccharomyces cerevisiae TREX-2 complex is more extensive but independent of the CID region.
J. Struct. Biol., 195, 2016
5OWU
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BU of 5owu by Molmil
Kap95:Nup1 complex
Descriptor: Importin subunit beta-1, Nucleoporin NUP1
Authors:Stewart, M.
Deposit date:2017-09-04
Release date:2017-10-25
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for the high-affinity binding of nucleoporin Nup1p to the Saccharomyces cerevisiae importin-beta homologue, Kap95p.
J. Mol. Biol., 349, 2005
5C5W
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BU of 5c5w by Molmil
1.25 A resolution structure of an RNA 20-mer
Descriptor: RNA (5'-R(P*CP*CP*UP*GP*AP*GP*UP*UP*CP*AP*AP*UP*UP*CP*UP*AP*GP*CP*G)-3')
Authors:Stewart, M, Valkov, E.
Deposit date:2015-06-22
Release date:2015-10-14
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:1.25 angstrom resolution structure of an RNA 20-mer that binds to the TREX2 complex.
Acta Crystallogr.,Sect.F, 71, 2015
3KJL
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BU of 3kjl by Molmil
Sgf11:Sus1 complex
Descriptor: Protein SUS1, SAGA-associated factor 11
Authors:Stewart, M, Ellisdon, A.M.
Deposit date:2009-11-03
Release date:2009-12-08
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural basis for the interaction between yeast Spt-Ada-Gcn5 acetyltransferase (SAGA) complex components Sgf11 and Sus1.
J.Biol.Chem., 285, 2010
3KIK
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BU of 3kik by Molmil
Sgf11:Sus1 complex
Descriptor: Protein SUS1, SAGA-associated factor 11
Authors:Stewart, M, Ellisdon, A.M.
Deposit date:2009-11-02
Release date:2009-12-08
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis for the interaction between yeast Spt-Ada-Gcn5 acetyltransferase (SAGA) complex components Sgf11 and Sus1
J.Biol.Chem., 285, 2010
2BVU
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BU of 2bvu by Molmil
D83R mutant of Asaris suum major sperm protein (MSP)
Descriptor: MAJOR SPERM PROTEIN, ISOFORM ALPHA
Authors:Stewart, M, Grant, R.P, Roberts, T.M.
Deposit date:2005-07-04
Release date:2006-10-25
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The Role of Filament-Packing Dynamics in Powering Amoeboid Cell Motility.
Proc.Natl.Acad.Sci.USA, 105, 2008
4LJ0
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BU of 4lj0 by Molmil
Nab2 Zn fingers complexed with polyadenosine
Descriptor: ACETATE ION, MAGNESIUM ION, Nab2, ...
Authors:Stewart, M, Kuhlmann, S.I, Valkov, E.
Deposit date:2013-07-04
Release date:2013-10-09
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structural basis for the molecular recognition of polyadenosine RNA by Nab2 Zn fingers.
Nucleic Acids Res., 42, 2014
3KND
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BU of 3knd by Molmil
TPX2:importin-alpha complex
Descriptor: Importin subunit alpha-2, SULFATE ION, Targeting protein for Xklp2
Authors:Stewart, M.
Deposit date:2009-11-12
Release date:2010-03-23
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.151 Å)
Cite:Novel binding of the mitotic regulator TPX2 (target protein for Xenopus kinesin-like protein 2) to importin-alpha.
J.Biol.Chem., 285, 2010
3LCN
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BU of 3lcn by Molmil
Nab2:Gfd1 complex
Descriptor: Nuclear polyadenylated RNA-binding protein NAB2, ZINC ION, mRNA transport factor GFD1
Authors:Stewart, M.
Deposit date:2010-01-11
Release date:2010-05-12
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for the function of the Saccharomyces cerevisiae Gfd1 protein in mRNA nuclear export.
J.Biol.Chem., 285, 2010
3FWB
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BU of 3fwb by Molmil
Sac3:Sus1:Cdc31 complex
Descriptor: Cell division control protein 31, Nuclear mRNA export protein SAC3, Protein SUS1
Authors:Stewart, M, Jani, D.
Deposit date:2009-01-17
Release date:2009-04-14
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Sus1, Cdc31, and the Sac3 CID region form a conserved interaction platform that promotes nuclear pore association and mRNA export.
Mol.Cell, 33, 2009

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