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6BCB
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BU of 6bcb by Molmil
A Complex between PH Domain of p114RhoGEF and Activated RhoA Bound to a GTP Analog
Descriptor: 1,2-ETHANEDIOL, 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, MAGNESIUM ION, ...
Authors:Sternweis, P.C, Chen, Z.
Deposit date:2017-10-20
Release date:2017-12-13
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.401 Å)
Cite:Crystal structures of the PH domains from Lbc family of RhoGEFs bound to activated RhoA GTPase.
Data Brief, 17, 2018
6BCA
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BU of 6bca by Molmil
A Complex between PH Domain of LbcRhoGEF (AKAP-Lbc) and Activated RhoA Bound to a GTP Analog
Descriptor: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, A-kinase anchor protein 13, MAGNESIUM ION, ...
Authors:Sternweis, P.C, Chen, Z.
Deposit date:2017-10-20
Release date:2017-12-13
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.995 Å)
Cite:Crystal structures of the PH domains from Lbc family of RhoGEFs bound to activated RhoA GTPase.
Data Brief, 17, 2018
3KZ1
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BU of 3kz1 by Molmil
Crystal Structure of the Complex of PDZ-RhoGEF DH/PH domains with GTP-gamma-S Activated RhoA
Descriptor: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, MAGNESIUM ION, Rho guanine nucleotide exchange factor 11, ...
Authors:Chen, Z, Sternweis, P.C, Sprang, S.R.
Deposit date:2009-12-07
Release date:2010-04-28
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Activated RhoA binds to the pleckstrin homology (PH) domain of PDZ-RhoGEF, a potential site for autoregulation.
J.Biol.Chem., 285, 2010
1SHZ
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BU of 1shz by Molmil
Crystal Structure of the p115RhoGEF rgRGS Domain in A Complex with Galpha(13):Galpha(i1) Chimera
Descriptor: GUANOSINE-5'-DIPHOSPHATE, Guanine Nucleotide-Binding Protein Galpha(13):Galpha(i1) Chimera, MAGNESIUM ION, ...
Authors:Chen, Z, Singer, W.D, Sternweis, P.C, Sprang, S.R.
Deposit date:2004-02-26
Release date:2005-01-18
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Structure of the p115RhoGEF rgRGS domain-Galpha13/i1 chimera complex suggests convergent evolution of a GTPase activator.
Nat.Struct.Mol.Biol., 12, 2005
6BC0
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BU of 6bc0 by Molmil
A Complex between PH Domain of p190RhoGEF and Activated RhoA Bound to a GTP Analog
Descriptor: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, MAGNESIUM ION, Rho guanine nucleotide exchange factor 28, ...
Authors:Chen, Z, Sternweis, P.C.
Deposit date:2017-10-20
Release date:2017-12-13
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.198 Å)
Cite:Direct regulation of p190RhoGEF by activated Rho and Rac GTPases.
J. Struct. Biol., 202, 2018
6BC1
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BU of 6bc1 by Molmil
A Complex between PH Domain of p190RhoGEF and Activated Rac1 Bound to a GTP Analog
Descriptor: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, MAGNESIUM ION, Ras-related C3 botulinum toxin substrate 1, ...
Authors:Chen, Z, Sternweis, P.C.
Deposit date:2017-10-20
Release date:2017-12-13
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Direct regulation of p190RhoGEF by activated Rho and Rac GTPases.
J. Struct. Biol., 202, 2018
3ODX
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BU of 3odx by Molmil
Crystal Structure of an N-terminally Truncated Linker-DH/PH Domains of p115-RhoGEF
Descriptor: Rho guanine nucleotide exchange factor 1
Authors:Chen, Z, Guo, L, Sprang, S.R, Sternweis, P.C.
Deposit date:2010-08-12
Release date:2011-01-05
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Modulation of a GEF switch: Autoinhibition of the intrinsic guanine nucleotide exchange activity of p115-RhoREF
Protein Sci., 20, 2011
3ODO
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BU of 3odo by Molmil
Crystal Structure of the DH/PH Domains of p115-RhoGEF
Descriptor: Rho guanine nucleotide exchange factor 1
Authors:Chen, Z, Guo, L, Sprang, S.R, Sternweis, P.C.
Deposit date:2010-08-11
Release date:2011-01-05
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Modulation of a GEF switch: Autoinhibition of the intrinsic guanine nucleotide exchange activity of p115-RhoREF
Protein Sci., 20, 2011
3ODW
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BU of 3odw by Molmil
Crystal Structure of the Linker-DH/PH domains of p115-RhoGEF
Descriptor: Rho guanine nucleotide exchange factor 1
Authors:Chen, Z, Guo, L, Sprang, S.R, Sternweis, P.C.
Deposit date:2010-08-11
Release date:2011-01-05
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Modulation of a GEF switch: Autoinhibition of the intrinsic guanine nucleotide exchange activity of p115-RhoREF
Protein Sci., 20, 2011
3P6A
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BU of 3p6a by Molmil
Crystal Structure of the DH/PH domains of p115-RhoGEF (R399E mutant)
Descriptor: Rho guanine nucleotide exchange factor 1
Authors:Chen, Z, Guo, L, Sprang, S.R, Sternweis, P.C.
Deposit date:2010-10-11
Release date:2011-01-05
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Modulation of a GEF switch: Autoinhibition of the intrinsic guanine nucleotide exchange activity of p115-RhoREF
Protein Sci., 20, 2011
5E6P
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BU of 5e6p by Molmil
PlexinB2 cytoplasmic region/PDZ-RhoGEF PDZ domain complex
Descriptor: Plexin-B2, Rho guanine nucleotide exchange factor 11
Authors:Pascoe, H.G, Zhang, X.
Deposit date:2015-10-10
Release date:2015-11-18
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.215 Å)
Cite:Secondary PDZ domain-binding site on class B plexins enhances the affinity for PDZ-RhoGEF.
Proc.Natl.Acad.Sci.USA, 112, 2015
1IAP
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BU of 1iap by Molmil
CRYSTAL STRUCTURE OF P115RHOGEF RGRGS DOMAIN
Descriptor: GUANINE NUCLEOTIDE EXCHANGE FACTOR P115RHOGEF
Authors:Sprang, S.R, Chen, Z.
Deposit date:2001-03-22
Release date:2001-09-05
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of the rgRGS domain of p115RhoGEF.
Nat.Struct.Biol., 8, 2001
3CX8
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BU of 3cx8 by Molmil
Crystal Structure of PDZRhoGEF rgRGS Domain in a Complex with Galpha-13 Bound to GTP-gamma-S
Descriptor: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, Guanine nucleotide-binding protein alpha-13 subunit, MAGNESIUM ION, ...
Authors:Sprang, S.R, Chen, Z.
Deposit date:2008-04-23
Release date:2008-10-28
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Recognition of the Activated States of Galpha13 by the rgRGS Domain of PDZRhoGEF.
Structure, 16, 2008
3CX7
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BU of 3cx7 by Molmil
Crystal Structure of PDZRhoGEF rgRGS Domain in a Complex with Galpha-13 Bound to GDP-AlF4
Descriptor: GUANOSINE-5'-DIPHOSPHATE, Glutamate Transporter Associated Protein 48, Guanine Nucleotide-Binding Protein Galpha 13, ...
Authors:Sprang, S.R, Chen, Z.
Deposit date:2008-04-23
Release date:2008-10-28
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Recognition of the Activated States of Galpha13 by the rgRGS Domain of PDZRhoGEF.
Structure, 16, 2008
3CX6
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BU of 3cx6 by Molmil
Crystal Structure of PDZRhoGEF rgRGS Domain in a Complex with Galpha-13 Bound to GDP
Descriptor: GUANOSINE-5'-DIPHOSPHATE, Guanine nucleotide-binding protein alpha-13 subunit, MAGNESIUM ION, ...
Authors:Sprang, S.R, Chen, Z.
Deposit date:2008-04-23
Release date:2008-10-28
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Recognition of the Activated States of Galpha13 by the rgRGS Domain of PDZRhoGEF.
Structure, 16, 2008

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