Author results

2VC2
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RE-REFINEMENT OF INTEGRIN ALPHAIIBBETA3 HEADPIECE BOUND TO ANTAGONIST L-739758
Descriptor:INTEGRIN ALPHA-IIB, INTEGRIN BETA-3, MONOCLONAL ANTIBODY 10E5 HEAVY CHAIN, ...
Authors:Springer, T.A., Zhu, J., Xiao, T.
Deposit date:2007-09-18
Release date:2008-09-02
Last modified:2019-11-20
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural Basis for Distinctive Recognition of Fibrinogen Gammac Peptide by the Platelet Integrin Alphaiibbeta3.
J.Cell Biol., 182, 2008
2VDK
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RE-REFINEMENT OF INTEGRIN ALPHAIIBBETA3 HEADPIECE
Descriptor:INTEGRIN ALPHA-IIB, INTEGRIN BETA-3, MONOCLONAL ANTIBODY 10E5 HEAVY CHAIN, ...
Authors:Springer, T.A., Zhu, J., Xiao, T.
Deposit date:2007-10-10
Release date:2008-09-02
Last modified:2019-11-20
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural Basis for Distinctive Recognition of Fibrinogen Gammac Peptide by the Platelet Integrin Alphaiibbeta3.
J.Cell Biol., 182, 2008
2VDL
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RE-REFINEMENT OF INTEGRIN ALPHAIIBBETA3 HEADPIECE
Descriptor:INTEGRIN ALPHA-IIB, INTEGRIN BETA-3, MONOCLONAL ANTIBODY 10E5 HEAVY CHAIN, ...
Authors:Springer, T.A., Zhu, J., Xiao, T.
Deposit date:2007-10-10
Release date:2008-09-02
Last modified:2019-02-06
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Structural Basis for Distinctive Recognition of Fibrinogen Gammac Peptide by the Platelet Integrin Alphaiibbeta3.
J.Cell Biol., 182, 2008
2VDM
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RE-REFINEMENT OF INTEGRIN ALPHAIIBBETA3 HEADPIECE BOUND TO ANTAGONIST TIROFIBAN
Descriptor:INTEGRIN ALPHA-IIB, INTEGRIN BETA-3, MONOCLONAL ANTIBODY 10E5 HEAVY CHAIN, ...
Authors:Springer, T.A., Zhu, J., Xiao, T.
Deposit date:2007-10-10
Release date:2008-09-02
Last modified:2019-11-20
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural Basis for Distinctive Recognition of Fibrinogen Gammac Peptide by the Platelet Integrin Alphaiibbeta3.
J.Cell Biol., 182, 2008
2VDN
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RE-REFINEMENT OF INTEGRIN ALPHAIIBBETA3 HEADPIECE BOUND TO ANTAGONIST EPTIFIBATIDE
Descriptor:INTEGRIN ALPHA-IIB, INTEGRIN BETA-3, EPTIFIBATIDE, ...
Authors:Springer, T.A., Zhu, J., Xiao, T.
Deposit date:2007-10-10
Release date:2008-09-02
Last modified:2019-11-20
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural Basis for Distinctive Recognition of Fibrinogen Gammac Peptide by the Platelet Integrin Alphaiibbeta3.
J.Cell Biol., 182, 2008
2VDO
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INTEGRIN ALPHAIIBBETA3 HEADPIECE BOUND TO FIBRINOGEN GAMMA CHAIN PEPTIDE, HHLGGAKQAGDV
Descriptor:INTEGRIN ALPHA-IIB, INTEGRIN BETA-3, FIBRINOGEN, ...
Authors:Springer, T.A., Zhu, J., Xiao, T.
Deposit date:2007-10-10
Release date:2008-09-02
Last modified:2019-02-06
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:Structural Basis for Distinctive Recognition of Fibrinogen Gammac Peptide by the Platelet Integrin Alphaiibbeta3.
J.Cell Biol., 182, 2008
2VDP
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INTEGRIN ALPHAIIBBETA3 HEADPIECE BOUND TO FIBRINOGEN GAMMA CHAIN PEPTIDE,LGGAKQAGDV
Descriptor:INTEGRIN ALPHA-IIB, INTEGRIN BETA-3, FIBRINOGEN, ...
Authors:Springer, T.A., Zhu, J., Xiao, T.
Deposit date:2007-10-10
Release date:2008-09-02
Last modified:2019-02-06
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural Basis for Distinctive Recognition of Fibrinogen Gammac Peptide by the Platelet Integrin Alphaiibbeta3.
J.Cell Biol., 182, 2008
2VDQ
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INTEGRIN ALPHAIIBBETA3 HEADPIECE BOUND TO A CHIMERIC FIBRINOGEN GAMMA CHAIN PEPTIDE, HHLGGAKQRGDV
Descriptor:INTEGRIN ALPHA-IIB, INTEGRIN BETA-3, FIBRINOGEN, ...
Authors:Springer, T.A., Zhu, J., Xiao, T.
Deposit date:2007-10-10
Release date:2008-09-02
Last modified:2019-11-20
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:Structural Basis for Distinctive Recognition of Fibrinogen Gammac Peptide by the Platelet Integrin Alphaiibbeta3.
J.Cell Biol., 182, 2008
2VDR
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INTEGRIN ALPHAIIBBETA3 HEADPIECE BOUND TO A CHIMERIC FIBRINOGEN GAMMA CHAIN PEPTIDE, LGGAKQRGDV
Descriptor:INTEGRIN ALPHA-IIB, INTEGRIN BETA-3, FIBRINOGEN, ...
Authors:Springer, T.A., Zhu, J., Xiao, T.
Deposit date:2007-10-10
Release date:2008-09-02
Last modified:2019-02-06
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural Basis for Distinctive Recognition of Fibrinogen Gammac Peptide by the Platelet Integrin Alphaiibbeta3.
J.Cell Biol., 182, 2008
4G1M
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RE-REFINEMENT OF ALPHA V BETA 3 STRUCTURE
Descriptor:Integrin alpha-V, Integrin beta-3, CALCIUM ION, ...
Authors:Springer, T.A., Mi, L., Zhu, J.
Deposit date:2012-07-10
Release date:2012-12-12
Last modified:2019-08-14
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Alpha V Beta 3 Integrin Crystal Structures and their Functional Implications
Biochemistry, 51, 2012
5E6S
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STRUCTURES OF LEUKOCYTE INTEGRIN ALB2: THE AI DOMAIN, THE HEADPIECE, AND THE POCKET FOR THE INTERNAL LIGAND
Descriptor:Integrin alpha-L, Integrin beta-2, MAGNESIUM ION, ...
Authors:Springer, T.A., Sen, M.
Deposit date:2015-10-10
Release date:2016-03-02
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Leukocyte integrin alpha L beta 2 headpiece structures: The alpha I domain, the pocket for the internal ligand, and concerted movements of its loops.
Proc.Natl.Acad.Sci.USA, 113, 2016
5E6W
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RE-REFINEMENT OF THE CRYSTAL STRUCTURE OF THE PLEXIN-SEMAPHORIN-INTEGRIN DOMAIN/HYBRID DOMAIN/I-EGF1 SEGMENT FROM THE HUMAN INTEGRIN B2 SUBUNIT
Descriptor:Integrin beta-2, N-ACETYL-D-GLUCOSAMINE
Authors:Springer, T.A., Sen, M.
Deposit date:2015-10-10
Release date:2016-03-02
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Leukocyte integrin alpha L beta 2 headpiece structures: The alpha I domain, the pocket for the internal ligand, and concerted movements of its loops.
Proc.Natl.Acad.Sci.USA, 113, 2016
5E6X
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RE-REFINEMENT OF THE CRYSTAL STRUCTURE OF THE PLEXIN-SEMAPHORIN-INTEGRIN DOMAIN/HYBRID DOMAIN/I-EGF1 SEGMENT FROM THE HUMAN INTEGRIN B2 SUBUNIT
Descriptor:Integrin beta-2, N-ACETYL-D-GLUCOSAMINE
Authors:Springer, T.A., Sen, M.
Deposit date:2015-10-10
Release date:2016-03-02
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Leukocyte integrin alpha L beta 2 headpiece structures: The alpha I domain, the pocket for the internal ligand, and concerted movements of its loops.
Proc.Natl.Acad.Sci.USA, 113, 2016
1BQS
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THE CRYSTAL STRUCTURE OF MUCOSAL ADDRESSIN CELL ADHESION MOLECULE-1 (MADCAM-1)
Descriptor:PROTEIN (MUCOSAL ADDRESSIN CELL ADHESION MOLECULE-1), 2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE
Authors:Tan, K., Casasnovas, J.M., Liu, J.H., Briskin, M.J., Springer, T.A., Wang, J.-H.
Deposit date:1998-08-18
Release date:1999-08-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The structure of immunoglobulin superfamily domains 1 and 2 of MAdCAM-1 reveals novel features important for integrin recognition.
Structure, 6, 1998
1L0Q
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TANDEM YVTN BETA-PROPELLER AND PKD DOMAINS FROM AN ARCHAEAL SURFACE LAYER PROTEIN
Descriptor:Surface layer protein
Authors:Jing, H., Takagi, J., Liu, J.-H., Lindgren, S., Zhang, R.-G., Joachimiak, A., Wang, J.-H., Springer, T.A.
Deposit date:2002-02-12
Release date:2002-11-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Archaeal Surface Layer Proteins Contain beta Propeller, PKD, and beta Helix Domains and Are Related to Metazoan Cell Surface Proteins.
Structure, 10, 2002
5VQF
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CRYSTAL STRUCTURE OF PRO-TGF-BETA 1
Descriptor:Transforming growth factor beta-1, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE
Authors:Zhao, B., Xu, S., Dong, X., Lu, C., Springer, T.A.
Deposit date:2017-05-08
Release date:2017-11-15
Last modified:2018-02-14
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Prodomain-growth factor swapping in the structure of pro-TGF-beta 1.
J. Biol. Chem., 293, 2018
1IC1
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THE CRYSTAL STRUCTURE FOR THE N-TERMINAL TWO DOMAINS OF ICAM-1
Descriptor:INTERCELLULAR ADHESION MOLECULE-1, N-ACETYL-D-GLUCOSAMINE, 2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE
Authors:Casasnovas, J.M., Stehle, T., Liu, J.-H., Wang, J.-H., Springer, T.A.
Deposit date:1998-03-09
Release date:1998-06-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:A dimeric crystal structure for the N-terminal two domains of intercellular adhesion molecule-1.
Proc.Natl.Acad.Sci.USA, 95, 1998
1IJQ
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CRYSTAL STRUCTURE OF THE LDL RECEPTOR YWTD-EGF DOMAIN PAIR
Descriptor:LOW-DENSITY LIPOPROTEIN RECEPTOR
Authors:Jeon, H., Meng, W., Takagi, J., Eck, M.J., Springer, T.A., Blacklow, S.C.
Deposit date:2001-04-27
Release date:2001-05-23
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Implications for familial hypercholesterolemia from the structure of the LDL receptor YWTD-EGF domain pair.
Nat.Struct.Biol., 8, 2001
1L3Y
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INTEGRIN EGF-LIKE MODULE 3 FROM THE BETA-2 SUBUNIT
Descriptor:Integrin beta-2:CYSTEINE-RICH MODULE 3
Authors:Beglova, N., Blacklow, S.C., Takagi, J., Springer, T.A.
Deposit date:2002-03-03
Release date:2002-04-01
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Cysteine-rich module structure reveals a fulcrum for integrin rearrangement upon activation.
Nat.Struct.Biol., 9, 2002
1MJN
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CRYSTAL STRUCTURE OF THE INTERMEDIATE AFFINITY AL I DOMAIN MUTANT
Descriptor:Integrin alpha-L, MAGNESIUM ION
Authors:Shimaoka, M., Xiao, T., Liu, J.H., Yang, Y.T., Dong, Y.C., Jun, C.D., McCormack, A., Zhang, R.G., Wang, J.H., Springer, T.A.
Deposit date:2002-08-28
Release date:2003-01-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Structures of the alphaL I Domain and its Complex with ICAM-1 reveal a Shape-shifting Pathway for Integrin Regulation
Cell(Cambridge,Mass.), 112, 2003
1MQ8
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CRYSTAL STRUCTURE OF ALPHAL I DOMAIN IN COMPLEX WITH ICAM-1
Descriptor:intercellular adhesion molecule-1, Integrin alpha-L, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Shimaoka, M., Xiao, T., Liu, J.-H., Yang, Y., Dong, Y., Jun, C.-D., McCormack, A., Zhang, R., Joachimiak, A., Takagi, J., Wang, J.-H., Springer, T.A.
Deposit date:2002-09-15
Release date:2003-01-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structures of the aL I domain and its complex with ICAM-1 reveal a shape-shifting pathway for integrin regulation
Cell(Cambridge,Mass.), 112, 2003
1MQ9
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CRYSTAL STRUCTURE OF HIGH AFFINITY ALPHAL I DOMAIN WITH LIGAND MIMETIC CRYSTAL CONTACT
Descriptor:Integrin alpha-L, MANGANESE (II) ION
Authors:Shimaoka, M., Xiao, T., Liu, J.-H., Yang, Y., Dong, Y., Jun, C.-D., McCormack, A., Zhang, R., Joachimiak, A., Takagi, J., Wang, J.-H., Springer, T.A.
Deposit date:2002-09-15
Release date:2003-01-14
Last modified:2011-11-16
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structures of the aL I domain and its complex with ICAM-1 reveal a shape-shifting pathway for integrin regulation
Cell(Cambridge,Mass.), 112, 2003
1MQA
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CRYSTAL STRUCTURE OF HIGH AFFINITY ALPHAL I DOMAIN IN THE ABSENCE OF LIGAND OR METAL
Descriptor:Integrin alpha-L
Authors:Shimaoka, T., Xiao, T., Liu, J.-H., Yang, Y., Dong, Y., Jun, C.-D., Zhang, R., Takagi, J., Wang, J.-H., Springer, T.A.
Deposit date:2002-09-15
Release date:2003-01-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structures of the aL I domain and its complex with ICAM-1 reveal a shape-shifting pathway for integrin regulation
Cell(Cambridge,Mass.), 112, 2003
1N3Y
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CRYSTAL STRUCTURE OF THE ALPHA-X BETA2 INTEGRIN I DOMAIN
Descriptor:Integrin alpha-X
Authors:Vorup-Jensen, T., Ostermeier, C., Shimaoka, M., Hommel, U., Springer, T.A.
Deposit date:2002-10-30
Release date:2003-02-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structure and allosteric regulation of the alpha X beta 2 integrin I domain.
Proc.Natl.Acad.Sci.USA, 100, 2003
1NPE
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CRYSTAL STRUCTURE OF NIDOGEN/LAMININ COMPLEX
Descriptor:nidogen, Laminin gamma-1 chain, CADMIUM ION
Authors:Takagi, J., Yang, Y.T., Liu, J.-H., Wang, J.-H., Springer, T.A.
Deposit date:2003-01-17
Release date:2003-08-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Complex between nidogen and laminin fragments reveals a paradigmatic beta-propeller interface
Nature, 424, 2003