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1S9V
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CRYSTAL STRUCTURE OF HLA-DQ2 COMPLEXED WITH DEAMIDATED GLIADIN PEPTIDE
分子名称:HLA class II histocompatibility antigen, DQ(3) alpha chain, DQ(1) beta chain, ...
著者Kim, C.-Y., Quarsten, H., Bergseng, E., Khosla, C., Sollid, L.M.
登録日2004-02-05
公開日2004-03-02
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.22 Å)
主引用文献Structural basis for HLA-DQ2-mediated presentation of gluten epitopes in celiac disease
Proc.Natl.Acad.Sci.USA, 101, 2004
4ZD3
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STRUCTURE OF A TRANSGLUTAMINASE 2-SPECIFIC AUTOANTIBODY FAB FRAGMENT
分子名称:679-14-14E06 Fab fragment heavy chain, 679-14-14E06 Fab fragment light chain
著者Chen, X., Dalhus, B., Hnida, K., Iversen, R., Sollid, L.M.
登録日2015-04-16
公開日2015-07-22
最終更新日2015-09-09
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural Basis for Antigen Recognition by Transglutaminase 2-specific Autoantibodies in Celiac Disease.
J.Biol.Chem., 290, 2015
5IFJ
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CRYSTAL STRUCTURE OF ANTI-GLIADIN 1002-1E01 FAB FRAGMENT IN COMPLEX OF PEPTIDE PLQPEQPFP
分子名称:1E01 Fab fragment heavy chain, 1E01 Fab fragment light chain, peptide PRO-LEU-GLN-PRO-GLU-GLN-PRO-PHE-PRO, ...
著者Snir, O., Chen, X., Gidoni, M., du Pre, M.F., Zhao, Y., Steinsbo, O., Lundin, K.E., Yaari, G., Sollid, L.M.
登録日2016-02-26
公開日2017-03-15
最終更新日2017-12-06
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Stereotyped antibody responses target posttranslationally modified gluten in celiac disease.
JCI Insight, 2, 2017
5IG7
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CRYSTAL STRUCTURE OF ANTI-GLIADIN 1002-1E01 FAB FRAGMENT IN COMPLEX OF PEPTIDE PLQPQQPFP
分子名称:1E01 Fab fragment heavy chain, 1E01 Fab fragment light chain, peptide PRO-LEU-GLN-PRO-GLN-GLN-PRO-PHE-PRO, ...
著者Snir, O., Chen, X., Gidoni, M., du Pre, M.F., Zhao, Y., Steinsbo, O., Lundin, K.E., Yaari, G., Sollid, L.M.
登録日2016-02-27
公開日2017-03-15
最終更新日2017-12-06
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Stereotyped antibody responses target posttranslationally modified gluten in celiac disease.
JCI Insight, 2, 2017
5IHZ
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CRYSTAL STRUCTURE OF ANTI-GLIADIN 1002-1E01 FAB FRAGMENT
分子名称:1E01 Fab fragment heavy chain, 1E01 Fab fragment light chain
著者Snir, O., Chen, X., Gidoni, M., du Pre, M.F., Zhao, Y., Steinsbo, O., Lundin, K.E., Yaari, G., Sollid, L.M.
登録日2016-03-01
公開日2017-03-15
最終更新日2017-12-06
実験手法X-RAY DIFFRACTION (1.64 Å)
主引用文献Stereotyped antibody responses target posttranslationally modified gluten in celiac disease.
JCI Insight, 2, 2017
5IJK
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CRYSTAL STRUCTURE OF ANTI-GLIADIN 1002-1E03 FAB FRAGMENT IN COMPLEX OF PEPTIDE PLQPEQPFP
分子名称:peptide PRO-LEU-GLN-PRO-GLU-GLN-PRO-PHE-PRO, 1E03 Fab fragment heavy chain, 1E03 Fab fragment light chain, ...
著者Snir, O., Chen, X., Gidoni, M., du Pre, M.F., Zhao, Y., Steinsbo, O., Lundin, K.E., Yaari, G., Sollid, L.M.
登録日2016-03-02
公開日2017-03-15
最終更新日2017-12-06
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Stereotyped antibody responses target posttranslationally modified gluten in celiac disease.
JCI Insight, 2, 2017
5IK3
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CRYSTAL STRUCTURE OF ANTI-GLIADIN 1002-1E03 FAB FRAGMENT
分子名称:1E03 Fab fragment heavy chain, 1E03 Fab fragment light chain, SULFATE ION
著者Snir, O., Chen, X., Gidoni, M., du Pre, M.F., Zhao, Y., Steinsbo, O., Lundin, K.E., Yaari, G., Sollid, L.M.
登録日2016-03-03
公開日2017-03-15
最終更新日2017-12-06
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Stereotyped antibody responses target posttranslationally modified gluten in celiac disease.
JCI Insight, 2, 2017
5IT2
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STRUCTURE OF A TRANSGLUTAMINASE 2-SPECIFIC AUTOANTIBODY 693-10-B06 FAB FRAGMENT
分子名称:heavy chain, light chain
著者Chen, X., Dalhus, B., Hnida, K., Iversen, R., Sollid, L.M.
登録日2016-03-16
公開日2017-03-22
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献High abundance of plasma cells secreting transglutaminase 2-specific IgA autoantibodies with limited somatic hypermutation in celiac disease intestinal lesions
Nat. Med., 18, 2012
5KSU
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CRYSTAL STRUCTURE OF HLA-DQ2.5-CLIP1 AT 2.73 RESOLUTION
分子名称:HLA class II histocompatibility antigen, DQ alpha 1 chain, MHC class II HLA-DQ-beta-1, ...
著者Nguyen, T.-B., Jayaraman, P., Bergseng, E., Madhusudhan, M.S., Kim, C.-Y., Sollid, L.M.
登録日2016-07-10
公開日2017-04-05
最終更新日2018-04-18
実験手法X-RAY DIFFRACTION (2.73 Å)
主引用文献Unraveling the structural basis for the unusually rich association of human leukocyte antigen DQ2.5 with class-II-associated invariant chain peptides.
J. Biol. Chem., 292, 2017
5KSV
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CRYSTAL STRUCTURE OF HLA-DQ2.5-CLIP2
分子名称:MHC class II HLA-DQ-alpha chain, MHC class II HLA-DQ-beta-1, HLA class II histocompatibility antigen gamma chain
著者Nguyen, T.B., Jayaraman, P., Bergseng, E., Madhusudhan, M.S., Kim, C.-Y., Sollid, L.M.
登録日2016-07-10
公開日2017-04-05
最終更新日2018-04-18
実験手法X-RAY DIFFRACTION (2.195 Å)
主引用文献Unraveling the structural basis for the unusually rich association of human leukocyte antigen DQ2.5 with class-II-associated invariant chain peptides.
J. Biol. Chem., 292, 2017
1YR2
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STRUCTURAL AND MECHANISTIC ANALYSIS OF TWO PROLYL ENDOPEPTIDASES: ROLE OF INTER-DOMAIN DYNAMICS IN CATALYSIS AND SPECIFICITY
分子名称:prolyl oligopeptidase, GLYCEROL
著者Shan, L., Mathews, I.I., Khosla, C.
登録日2005-02-02
公開日2005-03-15
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural and Mechanistic Analysis of Two Prolyl Endopeptidases: Role of Interdomain Dynamics in Catalysis and Specificity
Proc.Natl.Acad.Sci.USA, 102, 2005
2BKL
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STRUCTURAL AND MECHANISTIC ANALYSIS OF TWO PROLYL ENDOPEPTIDASES: ROLE OF INTER-DOMAIN DYNAMICS IN CATALYSIS AND SPECIFICITY
分子名称:PROLYL ENDOPEPTIDASE, N-[(BENZYLOXY)CARBONYL]-L-ALANYL-L-PROLINE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ...
著者Khosla, C., Shan, L., Mathews, I.I.
登録日2005-02-16
公開日2005-03-09
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structural and Mechanistic Analysis of Two Prolyl Endopeptidases: Role of Interdomain Dynamics in Catalysis and Specificity
Proc.Natl.Acad.Sci.USA, 102, 2005
2FO5
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CRYSTAL STRUCTURE OF RECOMBINANT BARLEY CYSTEINE ENDOPROTEASE B ISOFORM 2 (EP-B2) IN COMPLEX WITH LEUPEPTIN
分子名称:Cysteine proteinase EP-B 2, ACE-LEU-LEU-argininal (leupeptin), SULFATE ION
著者Bethune, M.T., Strop, P., Brunger, A.T., Khosla, C.
登録日2006-01-12
公開日2006-07-18
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Heterologous Expression, Purification, Refolding, and Structural-Functional Characterization of EP-B2, a Self-Activating Barley Cysteine Endoprotease.
Chem.Biol., 13, 2006
4D8P
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STRUCTURAL AND FUNCTIONAL STUDIES OF THE TRANS-ENCODED HLA-DQ2.3 (DQA1*03:01/DQB1*02:01) MOLECULE
分子名称:HLA-DQA1 protein, Peptide from Gamma-gliadin,HLA class II histocompatibility antigen, DQ beta 1 chain, ...
著者Kim, C.-Y., Hotta, K., Mathews, I.I., Chen, X.
登録日2012-01-11
公開日2012-03-14
最終更新日2017-06-21
実験手法X-RAY DIFFRACTION (3.05 Å)
主引用文献Structural and functional studies of trans-encoded HLA-DQ2.3 (DQA1*03:01/DQB1*02:01) protein molecule
J.Biol.Chem., 287, 2012
6MFF
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HLA-DQ2-GLIA-OMEGA1
分子名称:HLA class II histocompatibility antigen, DQ alpha 1 chain, MHC class II HLA-DQ-beta-1 - DQ2-glia-omega1 chimeric protein, ...
著者Petersen, J., Ciacchi, L., Rossjohn, J.
登録日2018-09-10
公開日2018-11-21
最終更新日2019-01-30
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Discriminative T-cell receptor recognition of highly homologous HLA-DQ2-bound gluten epitopes.
J. Biol. Chem., 294, 2019
6MFG
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HLA-DQ2-GLIA-ALPHA1
分子名称:HLA class II histocompatibility antigen, DQ alpha 1 chain, MHC class II HLA-DQ-beta-1 - DQ2-glia-alpha1 chimeric protein, ...
著者Petersen, J., Ciacchi, L., Rossjohn, J.
登録日2018-09-10
公開日2018-11-21
最終更新日2019-01-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Discriminative T-cell receptor recognition of highly homologous HLA-DQ2-bound gluten epitopes.
J. Biol. Chem., 294, 2019