3IQD
| Structure of Octopine-dehydrogenase in complex with NADH and Agmatine | Descriptor: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, AGMATINE, Octopine dehydrogenase | Authors: | Smits, S.H.J, Meyer, T, Mueller, A, Willbold, D, Grieshaber, M.K, Schmitt, L. | Deposit date: | 2009-08-20 | Release date: | 2010-08-25 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Insights into the mechanism of ligand binding to octopine dehydrogenase from Pecten maximus by NMR and crystallography Plos One, 5, 2010
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3CHG
| The compatible solute-binding protein OpuAC from Bacillus subtilis in complex with DMSA | Descriptor: | (dimethyl-lambda~4~-sulfanyl)acetic acid, Glycine betaine-binding protein | Authors: | Smits, S.H.J, Hoing, M, Lecher, J, Jebbar, M, Schmitt, L, Bremer, E. | Deposit date: | 2008-03-09 | Release date: | 2008-08-12 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | The Compatible-Solute-Binding Protein OpuAC from Bacillus subtilis: Ligand Binding, Site-Directed Mutagenesis, and Crystallographic Studies J.Bacteriol., 190, 2008
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6Z68
| A novel metagenomic alpha/beta-fold esterase | Descriptor: | Acetyl esterase/lipase, DI(HYDROXYETHYL)ETHER, MAGNESIUM ION, ... | Authors: | Bollinger, A, Thies, S, Hoeppner, A, Kobus, S, Jaeger, K.-E, Smits, S.H.J. | Deposit date: | 2020-05-28 | Release date: | 2020-12-30 | Last modified: | 2021-06-16 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | Crystal structures of a novel family IV esterase in free and substrate-bound form. Febs J., 288, 2021
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6Z69
| A novel metagenomic alpha/beta-fold esterase | Descriptor: | 7-hydroxy-4-methyl-2H-chromen-2-one, Acetyl esterase/lipase, MAGNESIUM ION, ... | Authors: | Bollinger, A, Thies, S, Hoeppner, A, Kobus, S, Jaeger, K.-E, Smits, S.H.J. | Deposit date: | 2020-05-28 | Release date: | 2020-12-30 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.81 Å) | Cite: | Crystal structures of a novel family IV esterase in free and substrate-bound form. Febs J., 288, 2021
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8A2C
| The crystal structure of the S178A mutant of PET40, a PETase enzyme from an unclassified Amycolatopsis | Descriptor: | 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CHLORIDE ION, ... | Authors: | Costanzi, E, Applegate, V, Port, A, Smits, S.H.J. | Deposit date: | 2022-06-03 | Release date: | 2023-06-14 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | The metagenome-derived esterase PET40 hydrolyses polyethylene terephthalate (PET) and is well conserved in the GC-rich gram-positives Amycolatopsis and Streptomyces To Be Published
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8B4U
| The crystal structure of PET46, a PETase enzyme from Candidatus bathyarchaeota | Descriptor: | 1,2-ETHANEDIOL, Alpha/beta hydrolase, CHLORIDE ION, ... | Authors: | Costanzi, E, Applegate, V, Schumacher, J, Smits, S.H.J. | Deposit date: | 2022-09-21 | Release date: | 2023-08-23 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.71 Å) | Cite: | An archaeal lid-containing feruloyl esterase degrades polyethylene terephthalate. Commun Chem, 6, 2023
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3B5J
| Crystal Structures of the S504A Mutant of an Isolated ABC-ATPase in Complex with TNP-ADP | Descriptor: | 2',3'-O-[(1R,6R)-2,4,6-trinitrocyclohexa-2,4-diene-1,1-diyl]adenosine 5'-(trihydrogen diphosphate), Alpha-hemolysin translocation ATP-binding protein hlyB | Authors: | Oswald, C, Jenewein, S, Smits, S.H.J, Holland, I.B, Schmitt, L. | Deposit date: | 2007-10-26 | Release date: | 2008-01-15 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Water-mediated protein-fluorophore interactions modulate the affinity of an ABC-ATPase/TNP-ADP complex J.Struct.Biol., 162, 2008
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8B6E
| crystal structure of the DNA-binding short chromatophore-targeted protein sCTP-23166 from Paulinella chromatophora | Descriptor: | 1,2-ETHANEDIOL, SODIUM ION, sCTP-23166 | Authors: | Macorano, L, Applegate, V, Hoeppner, A, Smits, S.H.J, Nowack, E.C.M. | Deposit date: | 2022-09-27 | Release date: | 2023-07-12 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | DNA-binding and protein structure of nuclear factors likely acting in genetic information processing in the Paulinella chromatophore. Proc.Natl.Acad.Sci.USA, 120, 2023
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6SBN
| Polyester hydrolase PE-H of Pseudomonas aestusnigri | Descriptor: | ACETATE ION, SODIUM ION, polyester hydrolase | Authors: | Bollinger, A, Thies, S, Kobus, S, Hoeppner, A, Smits, S.H.J, Jaeger, K.-E. | Deposit date: | 2019-07-22 | Release date: | 2020-02-26 | Last modified: | 2020-03-11 | Method: | X-RAY DIFFRACTION (1.09 Å) | Cite: | A Novel Polyester Hydrolase From the Marine BacteriumPseudomonas aestusnigri -Structural and Functional Insights. Front Microbiol, 11, 2020
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6SCD
| Polyester hydrolase PE-H Y250S mutant of Pseudomonas aestusnigri | Descriptor: | ACETATE ION, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | Authors: | Bollinger, A, Thies, S, Kobus, S, Hoeppner, A, Smits, S.H.J, Jaeger, K.-E. | Deposit date: | 2019-07-24 | Release date: | 2020-02-26 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | A Novel Polyester Hydrolase From the Marine BacteriumPseudomonas aestusnigri -Structural and Functional Insights. Front Microbiol, 11, 2020
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6SL8
| Diaminobutyrate acetyltransferase EctA from Paenibacillus lautus in complex with its substrate L-2,4-diaminobutyric acid (DAB) | Descriptor: | 2,4-DIAMINOBUTYRIC ACID, GLYCEROL, L-2,4-diaminobutyric acid acetyltransferase, ... | Authors: | Richter, A.A, Kobus, S, Czech, L, Hoeppner, A, Bremer, E, Smits, S.H.J. | Deposit date: | 2019-08-19 | Release date: | 2020-01-29 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.53 Å) | Cite: | The architecture of the diaminobutyrate acetyltransferase active site provides mechanistic insight into the biosynthesis of the chemical chaperone ectoine. J.Biol.Chem., 295, 2020
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6SLL
| Diaminobutyrate acetyltransferase EctA from Paenibacillus lautus in complex with its substrate L-2,4-diaminobutyric acid (DAB) and coenzyme A | Descriptor: | 2,4-DIAMINOBUTYRIC ACID, COENZYME A, L-2,4-diaminobutyric acid acetyltransferase, ... | Authors: | Richter, A.A, Kobus, S, Czech, L, Hoeppner, A, Bremer, E, Smits, S.H.J. | Deposit date: | 2019-08-20 | Release date: | 2020-01-29 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | The architecture of the diaminobutyrate acetyltransferase active site provides mechanistic insight into the biosynthesis of the chemical chaperone ectoine. J.Biol.Chem., 295, 2020
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6SK1
| Diaminobutyrate acetyltransferase EctA from Paenibacillus lautus in complex with coenzyme A | Descriptor: | ACETATE ION, COENZYME A, L-2,4-diaminobutyric acid acetyltransferase | Authors: | Richter, A.A, Kobus, S, Czech, L, Hoeppner, A, Bremer, E, Smits, S.H.J. | Deposit date: | 2019-08-14 | Release date: | 2020-01-29 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | The architecture of the diaminobutyrate acetyltransferase active site provides mechanistic insight into the biosynthesis of the chemical chaperone ectoine. J.Biol.Chem., 295, 2020
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6SJY
| Diaminobutyrate acetyltransferase EctA from Paenibacillus lautus in complex with its product ADABA | Descriptor: | (2~{S})-4-acetamido-2-azanyl-butanoic acid, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLYCEROL, ... | Authors: | Richter, A.A, Kobus, S, Czech, L, Hoeppner, A, Bremer, E, Smits, S.H.J. | Deposit date: | 2019-08-14 | Release date: | 2020-01-29 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | The architecture of the diaminobutyrate acetyltransferase active site provides mechanistic insight into the biosynthesis of the chemical chaperone ectoine. J.Biol.Chem., 295, 2020
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6SLK
| Diaminobutyrate acetyltransferase EctA from Paenibacillus lautus | Descriptor: | L-2,4-diaminobutyric acid acetyltransferase, SODIUM ION, SULFATE ION | Authors: | Richter, A.A, Kobus, S, Czech, L, Hoeppner, A, Bremer, E, Smits, S.H.J. | Deposit date: | 2019-08-20 | Release date: | 2020-01-29 | Last modified: | 2021-06-30 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | The architecture of the diaminobutyrate acetyltransferase active site provides mechanistic insight into the biosynthesis of the chemical chaperone ectoine. J.Biol.Chem., 295, 2020
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3C7A
| A structural basis for substrate and stereo selectivity in octopine dehydrogenase (ODH-NADH) | Descriptor: | 1,2-ETHANEDIOL, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Octopine dehydrogenase | Authors: | Smits, S.H.J, Mueller, A, Schmitt, L, Grieshaber, M.K. | Deposit date: | 2008-02-07 | Release date: | 2008-07-22 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | A structural basis for substrate selectivity and stereoselectivity in octopine dehydrogenase from Pecten maximus. J.Mol.Biol., 381, 2008
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3C7D
| A structural basis for substrate and stereo selectivity in octopine dehydrogenase (ODH-NADH-Pyruvate) | Descriptor: | NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Octopine dehydrogenase, PYRUVIC ACID | Authors: | Smits, S.H.J, Mueller, A, Schmitt, L, Grieshaber, M.K. | Deposit date: | 2008-02-07 | Release date: | 2008-07-22 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | A structural basis for substrate selectivity and stereoselectivity in octopine dehydrogenase from Pecten maximus. J.Mol.Biol., 381, 2008
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3C7C
| A structural basis for substrate and stereo selectivity in octopine dehydrogenase (ODH-NADH-L-Arginine) | Descriptor: | ARGININE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Octopine dehydrogenase | Authors: | Smits, S.H.J, Mueller, A, Schmitt, L, Grieshaber, M.K. | Deposit date: | 2008-02-07 | Release date: | 2008-07-22 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | A structural basis for substrate selectivity and stereoselectivity in octopine dehydrogenase from Pecten maximus. J.Mol.Biol., 381, 2008
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6HRG
| Structure of Igni18, a novel metallo hydrolase from the hyperthermophilic archaeon Ignicoccus hospitalis KIN4/I | Descriptor: | PHOSPHATE ION, POTASSIUM ION, UPF0173 metal-dependent hydrolase Igni_1254, ... | Authors: | Smits, S.H, Streit, W.R, Jaeger, K.E, Hoeppner, A. | Deposit date: | 2018-09-26 | Release date: | 2019-10-09 | Last modified: | 2021-03-17 | Method: | X-RAY DIFFRACTION (2.12 Å) | Cite: | A promiscuous ancestral enzyme ́s structure unveils protein variable regions of the highly diverse metallo-beta-lactamase family. Commun Biol, 4, 2021
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5NXY
| Crystal structure of OpuAC from B. subtilis in complex with Arsenobetaine | Descriptor: | 1,2-ETHANEDIOL, 2-(trimethyl-lambda~5~-arsanyl)ethanol, Osmotically activated L-carnitine/choline ABC transporter substrate-binding protein OpuCC | Authors: | Hofmann, T, Bremer, E, Schmitt, L, Smits, S. | Deposit date: | 2017-05-11 | Release date: | 2018-03-14 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Arsenobetaine: an ecophysiologically important organoarsenical confers cytoprotection against osmotic stress and growth temperature extremes. Environ. Microbiol., 20, 2018
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5NXX
| Crystal structure of OpuAC from B. subtilis in complex with Arsenobetaine | Descriptor: | (trimethylarsonio)acetate, Glycine betaine ABC transport system glycine betaine-binding protein OpuAC | Authors: | Hofmann, T, Bremer, E, Schmitt, L, Smits, S. | Deposit date: | 2017-05-11 | Release date: | 2018-03-28 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Arsenobetaine: an ecophysiologically important organoarsenical confers cytoprotection against osmotic stress and growth temperature extremes. Environ. Microbiol., 20, 2018
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7ZBR
| Crystal Structure of full-length Bartonella Effector protein 1 | Descriptor: | Bartonella effector protein (Bep) substrate of VirB T4SS | Authors: | Huber, M. | Deposit date: | 2022-03-24 | Release date: | 2023-04-05 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Full-length structure of a FIC effector protein from Bartonella reveals a novel structural domain To be published
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8BYK
| The structure of MadC from Clostridium maddingley reveals new insights into class I lanthipeptide cyclases | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, CHLORIDE ION, ... | Authors: | Knospe, C.V, Kamel, M, Spitz, O, Hoeppner, A, Galle, S, Reiners, J, Kedrov, A, Smits, S.H, Schmitt, L. | Deposit date: | 2022-12-13 | Release date: | 2023-02-22 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | The structure of MadC from Clostridium maddingley reveals new insights into class I lanthipeptide cyclases. Front Microbiol, 13, 2022
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3R6U
| Crystal structure of choline binding protein OpuBC from Bacillus subtilis | Descriptor: | CHOLINE ION, Choline-binding protein | Authors: | Pittelkow, M, Tschapek, B, Smits, S.H.J, Schmitt, L, Bremer, E. | Deposit date: | 2011-03-22 | Release date: | 2011-06-15 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.61 Å) | Cite: | The Crystal Structure of the Substrate-Binding Protein OpuBC from Bacillus subtilis in Complex with Choline. J.Mol.Biol., 411, 2011
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1I1G
| CRYSTAL STRUCTURE OF THE LRP-LIKE TRANSCRIPTIONAL REGULATOR FROM THE ARCHAEON PYROCOCCUS FURIOSUS | Descriptor: | TRANSCRIPTIONAL REGULATOR LRPA | Authors: | Leonard, P.M, Smits, S.H.J, Sedelnikova, S.E, Brinkman, A.B, de Vos, W.M, van der Oost, J, Rice, D.W, Rafferty, J.B. | Deposit date: | 2001-02-01 | Release date: | 2002-02-06 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Crystal structure of the Lrp-like transcriptional regulator from the archaeon Pyrococcus furiosus. EMBO J., 20, 2001
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