Author results

3L6G
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CRYSTAL STRUCTURE OF LACTOCOCCAL OPUAC IN ITS OPEN CONFORMATION
Descriptor:Betaine ABC transporter permease and substrate binding protein, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL
Authors:Berntsson, R.P.A., Wolters, J.C., Gul, N., Karasawa, A., Thunnissen, A.M.W.H., Slotboom, D.J., Poolman, B.
Deposit date:2009-12-23
Release date:2010-05-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Ligand binding and crystal structures of the substrate-binding domain of the ABC transporter OpuA.
Plos One, 5, 2010
3L6H
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CRYSTAL STRUCTURE OF LACTOCOCCAL OPUAC IN ITS CLOSED-LIGANDED CONFORMATION COMPLEXED WITH GLYCINE BETAINE
Descriptor:Betaine ABC transporter permease and substrate binding protein, TRIMETHYL GLYCINE, CHLORIDE ION
Authors:Berntsson, R.P.A., Wolters, J.C., Gul, N., Karasawa, A., Thunnissen, A.M.W.H., Slotboom, D.J., Poolman, B.
Deposit date:2009-12-23
Release date:2010-05-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Ligand binding and crystal structures of the substrate-binding domain of the ABC transporter OpuA.
Plos One, 5, 2010
3RLB
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CRYSTAL STRUCTURE AT 2.0 A OF THE S-COMPONENT FOR THIAMIN FROM AN ECF-TYPE ABC TRANSPORTER
Descriptor:ThiT, B-NONYLGLUCOSIDE, 3-(4-AMINO-2-METHYL-PYRIMIDIN-5-YLMETHYL)-5-(2-HYDROXY-ETHYL)-4-METHYL-THIAZOL-3-IUM
Authors:Erkens, G.B., Berntsson, R.P.-A., Fulyani, F., Majsnerowska, M., Vujicic-Zagar, A., ter Beek, J., Poolman, B., Slotboom, D.J.
Deposit date:2011-04-19
Release date:2011-06-29
Last modified:2011-07-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:The structural basis of modularity in ECF-type ABC transporters.
Nat.Struct.Mol.Biol., 18, 2011
3TCF
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CRYSTAL STRUCTURE OF E. COLI OPPA COMPLEXED WITH ENDOGENOUS LIGANDS
Descriptor:Periplasmic oligopeptide-binding protein, Endogenous peptide
Authors:Klepsch, M.M., Kovermann, M., Low, C., Balbach, J., de Gier, J.W., Slotboom, D.J., Berntsson, R.P.-A.
Deposit date:2011-08-09
Release date:2011-10-12
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2 Å)
Cite:Escherichia coli peptide binding protein OppA has a preference for positively charged peptides.
J.Mol.Biol., 414, 2011
3TCG
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CRYSTAL STRUCTURE OF E. COLI OPPA COMPLEXED WITH THE TRIPEPTIDE KGE
Descriptor:Periplasmic oligopeptide-binding protein, KGE Peptide
Authors:Klepsch, M.M., Kovermann, M., Low, C., Balbach, J., de Gier, J.W., Slotboom, D.J., Berntsson, R.P.-A.
Deposit date:2011-08-09
Release date:2011-10-12
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2 Å)
Cite:Escherichia coli peptide binding protein OppA has a preference for positively charged peptides.
J.Mol.Biol., 414, 2011
3TCH
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CRYSTAL STRUCTURE OF E. COLI OPPA IN AN OPEN CONFORMATION
Descriptor:Periplasmic oligopeptide-binding protein
Authors:Klepsch, M.M., Kovermann, M., Low, C., Balbach, J., de Gier, J.W., Slotboom, D.J., Berntsson, R.P.-A.
Deposit date:2011-08-09
Release date:2011-10-12
Last modified:2012-01-11
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Escherichia coli peptide binding protein OppA has a preference for positively charged peptides.
J.Mol.Biol., 414, 2011
3ZKK
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STRUCTURE OF THE XYLO-OLIGOSACCHARIDE SPECIFIC SOLUTE BINDING PROTEIN FROM BIFIDOBACTERIUM ANIMALIS SUBSP. LACTIS BL-04 IN COMPLEX WITH XYLOTETRAOSE
Descriptor:XOS BINDING PROTEIN, 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, BETA-D-XYLOPYRANOSE
Authors:Ejby, M., Vujicic-Zagar, A., Fredslund, F., Svensson, B., Slotboom, D.J., Abou Hachem, M.
Deposit date:2013-01-23
Release date:2013-10-30
Last modified:2019-02-06
Method:X-RAY DIFFRACTION (2.198 Å)
Cite:Structural Basis for Arabinoxylo-Oligosaccharide Capture by the Probiotic Bifidobacterium Animalis Subsp. Lactis Bl-04
Mol.Microbiol., 90, 2013
3ZKL
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STRUCTURE OF THE XYLO-OLIGOSACCHARIDE SPECIFIC SOLUTE BINDING PROTEIN FROM BIFIDOBACTERIUM ANIMALIS SUBSP. LACTIS BL-04 IN COMPLEX WITH XYLOTRIOSE
Descriptor:PUTATIVE SUGAR TRANSPORTER SOLUTE-BINDING PROTEIN, PENTAETHYLENE GLYCOL, BETA-D-XYLOPYRANOSE
Authors:Ejby, M., Vujicic-Zagar, A., Fredslund, F., Svensson, B., Slotboom, D.J., Abou Hachem, M.
Deposit date:2013-01-23
Release date:2013-10-30
Last modified:2019-02-06
Method:X-RAY DIFFRACTION (2.397 Å)
Cite:Structural Basis for Arabinoxylo-Oligosaccharide Capture by the Probiotic Bifidobacterium Animalis Subsp. Lactis Bl-04
Mol.Microbiol., 90, 2013
4C1T
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STRUCTURE OF THE XYLO-OLIGOSACCHARIDE SPECIFIC SOLUTE BINDING PROTEIN FROM BIFIDOBACTERIUM ANIMALIS SUBSP. LACTIS BL-04 IN COMPLEX WITH ARABINOXYLOTRIOSE
Descriptor:SUGAR TRANSPORTER SOLUTE-BINDING PROTEIN, ALPHA-L-ARABINOFURANOSE, BETA-D-XYLOPYRANOSE, ...
Authors:Fredslund, F., Ejby, M., Vujicic-Zagar, A., Svensson, B., Slotboom, D.J., Abou Hachem, M.
Deposit date:2013-08-13
Release date:2013-10-30
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (2.39 Å)
Cite:Structural Basis for Arabinoxylo-Oligosaccharide Capture by the Probiotic Bifidobacterium Animalis Subsp. Lactis Bl-04
Mol.Microbiol., 90, 2013
4C1U
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STRUCTURE OF THE XYLO-OLIGOSACCHARIDE SPECIFIC SOLUTE BINDING PROTEIN FROM BIFIDOBACTERIUM ANIMALIS SUBSP. LACTIS BL-04 IN COMPLEX WITH ARABINOXYLOBIOSE
Descriptor:SUGAR TRANSPORTER SOLUTE-BINDING PROTEIN, ALPHA-L-ARABINOFURANOSE, BETA-D-XYLOPYRANOSE, ...
Authors:Fredslund, F., Ejby, M., Vujicic-Zagar, A., Svensson, B., Slotboom, D.J., Abou Hachem, M.
Deposit date:2013-08-13
Release date:2013-10-30
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Basis for Arabinoxylo-Oligosaccharide Capture by the Probiotic Bifidobacterium Animalis Subsp. Lactis Bl-04
Mol.Microbiol., 90, 2013
4DVE
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CRYSTAL STRUCTURE AT 2.1 A OF THE S-COMPONENT FOR BIOTIN FROM AN ECF-TYPE ABC TRANSPORTER
Descriptor:Biotin transporter BioY, BIOTIN, B-NONYLGLUCOSIDE
Authors:Berntsson, R.P.-A., ter Beek, J., Majsnerowska, M., Duurkens, R., Puri, P., Poolman, B., Slotboom, D.J.
Deposit date:2012-02-23
Release date:2012-08-29
Last modified:2012-10-17
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Structural divergence of paralogous S components from ECF-type ABC transporters.
Proc.Natl.Acad.Sci.USA, 109, 2012
4FAJ
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STRUCTURE AND MODE OF PEPTIDE BINDING OF PHEROMONE RECEPTOR PRGZ
Descriptor:PrgZ, Sex pheromone cCF10, GLYCEROL, ...
Authors:Berntsson, R.P.-A., Schuurman-Wolters, G.K., Dunny, K., Slotboom, D.J., Poolman, B.
Deposit date:2012-05-22
Release date:2012-09-12
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure and Mode of Peptide Binding of Pheromone Receptor PrgZ.
J.Biol.Chem., 287, 2012
4KPT
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CRYSTAL STRUCTURE OF SUBSTRATE BINDING DOMAIN 1 (SBD1) OF ABC TRANSPORTER GLNPQ FROM LACTOCOCCUS LACTIS
Descriptor:Glutamine ABC transporter permease and substrate binding protein protein, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, HEXAETHYLENE GLYCOL, ...
Authors:Vujicic Zagar, A., Guskov, A., Schuurman-Wolters, G.K., Slotboom, D.J., Poolman, B.
Deposit date:2013-05-14
Release date:2013-09-11
Last modified:2013-11-20
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Functional Diversity of Tandem Substrate-Binding Domains in ABC Transporters from Pathogenic Bacteria.
Structure, 21, 2013
4KQP
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CRYSTAL STRUCTURE OF LACTOCOCCUS LACTIS GLNP SUBSTRATE BINDING DOMAIN 2 (SBD2) IN COMPLEX WITH GLUTAMINE AT 0.95 A RESOLUTION
Descriptor:Glutamine ABC transporter permease and substrate binding protein protein, GLUTAMINE
Authors:Vujicic Zagar, A., Guskov, A., Schuurman-Wolters, G.K., Slotboom, D.J., Poolman, B.
Deposit date:2013-05-15
Release date:2013-09-11
Last modified:2013-11-20
Method:X-RAY DIFFRACTION (0.95 Å)
Cite:Functional Diversity of Tandem Substrate-Binding Domains in ABC Transporters from Pathogenic Bacteria.
Structure, 21, 2013
4KR5
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CRYSTAL STRUCTURE OF LACTOCOCCUS LACTIS GLNP SUBSTRATE BINDING DOMAIN 2 (SBD2) IN OPEN CONFORMATION
Descriptor:Glutamine ABC transporter permease and substrate binding protein protein, MAGNESIUM ION, CHLORIDE ION, ...
Authors:Vujicic Zagar, A., Guskov, A., Schuurman-Wolters, G.K., Slotboom, D.J., Poolman, B.
Deposit date:2013-05-16
Release date:2013-09-11
Last modified:2013-11-20
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Functional Diversity of Tandem Substrate-Binding Domains in ABC Transporters from Pathogenic Bacteria.
Structure, 21, 2013
4KY0
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CRYSTAL STRUCTURE OF A SUBSTRATE-FREE GLUTAMATE TRANSPORTER HOMOLOGUE FROM THERMOCOCCUS KODAKARENSIS
Descriptor:Proton/glutamate symporter, SDF family, TETRAETHYLENE GLYCOL
Authors:Guskov, A., Jensen, S., Rempel, S., Hanelt, I., Slotboom, D.J.
Deposit date:2013-05-28
Release date:2013-09-11
Last modified:2013-10-23
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure of a substrate-free aspartate transporter.
Nat.Struct.Mol.Biol., 20, 2013
4LA9
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CRYSTAL STRUCTURE OF AN EMPTY SUBSTRATE BINDING DOMAIN 1 (SBD1) OF ABC TRANSPORTER GLNPQ FROM LACTOCOCCUS LACTIS
Descriptor:Glutamine ABC transporter permease and substrate binding protein protein, DI(HYDROXYETHYL)ETHER, PHOSPHATE ION
Authors:Guskov, A., Schuurman-Wolters, G.K., Slotboom, D.J., Poolman, B.
Deposit date:2013-06-19
Release date:2013-09-11
Last modified:2013-11-20
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Functional Diversity of Tandem Substrate-Binding Domains in ABC Transporters from Pathogenic Bacteria.
Structure, 21, 2013
4MES
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CRYSTAL STRUCTURE OF THIT COMPLEXED WITH LMG116
Descriptor:Thiamine transporter ThiT, B-NONYLGLUCOSIDE, 2-{3-[(4-amino-2-methylpyrimidin-5-yl)methyl]phenyl}ethanol, ...
Authors:Swier, L.J.Y.M., Guskov, A., Slotboom, D.J.
Deposit date:2013-08-27
Release date:2014-08-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structures of ThiT with small molecule modulators
To be Published
4MHW
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CRYSTAL STRUCTURE OF THIT WITH SMALL MOLECULE BAT-25
Descriptor:Thiamine transporter ThiT, 2-{4-[(4-amino-2-methylpyrimidin-5-yl)methyl]-3-methylthiophen-2-yl}ethanol, B-NONYLGLUCOSIDE, ...
Authors:Swier, L.J.Y.M., Guskov, A., Slotboom, D.J.
Deposit date:2013-08-30
Release date:2014-09-03
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of ThiT with small molecules modulators
To be Published
4MUU
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STRUCTURE OF THIT WITH PYRITHIAMINE BOUND
Descriptor:Thiamine transporter ThiT, 1-[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]-3-(2-HYDROXYETHYL)-2-METHYLPYRIDINIUM, B-NONYLGLUCOSIDE, ...
Authors:Swier, L.J.Y.M., Guskov, A., Slotboom, D.J.
Deposit date:2013-09-23
Release date:2014-09-17
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural studies on the thiamin binding protein ThiT
To be Published
4N4D
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STRUCTURE OF THIT WITH AV-38 BOUND
Descriptor:thiamine binding protein ThiT, {3-[(4-amino-2-methylpyrimidin-5-yl)methyl]phenyl}methanol, B-NONYLGLUCOSIDE, ...
Authors:Swier, L.J.Y.M., Guskov, A., Slotboom, D.J.
Deposit date:2013-10-08
Release date:2014-09-17
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural studies on the thiamine binding protein ThiT
To be Published
4POP
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THIT WITH LMG139 BOUND
Descriptor:Thiamine transporter ThiT, 4-[(4-amino-2-methylpyrimidin-5-yl)methyl]-3-methylthiophene-2-carbaldehyde, 2-(2-METHOXYETHOXY)ETHANOL, ...
Authors:Swier, L.J.Y.M., Guskov, A., Slotboom, D.J.
Deposit date:2014-02-26
Release date:2014-09-17
Last modified:2015-04-01
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure-Based Design of Potent Small-Molecule Binders to the S-Component of the ECF Transporter for Thiamine.
Chembiochem, 16, 2015
4POV
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THIT WITH LMG135 BOUND
Descriptor:Thiamine transporter ThiT, 4-[(4-amino-2-methylpyrimidin-5-yl)methyl]-3-methylthiophene-2-carbaldehyde, 2-(2-METHOXYETHOXY)ETHANOL, ...
Authors:Swier, L.J.Y.M., Guskov, A., Slotboom, D.J.
Deposit date:2014-02-26
Release date:2014-09-17
Last modified:2015-04-01
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure-Based Design of Potent Small-Molecule Binders to the S-Component of the ECF Transporter for Thiamine.
Chembiochem, 16, 2015
4QTN
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CRYSTAL STRUCTURE OF THE VITAMIN B3 TRANSPORTER PNUC
Descriptor:Nicotinamide riboside transporter PnuC, Nicotinamide riboside, B-OCTYLGLUCOSIDE
Authors:Guskov, A., Jaehme, M., Slotboom, D.J.
Deposit date:2014-07-08
Release date:2014-10-08
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of the Vitamin B3 transporter PnuC
Nat.Struct.Mol.Biol., 2014
4ZS9
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RAFFINOSE AND PANOSE BINDING PROTEIN FROM BIFIDOBACTERIUM ANIMALIS SUBSP. LACTIS BL-04, BOUND WITH RAFFINOSE
Descriptor:Sugar binding protein of ABC transporter system, raffinose, MAGNESIUM ION, ...
Authors:Fredslund, F., Ejby, M., Andersen, J.M., Slotboom, D.J., Abou Hachem, M.
Deposit date:2015-05-13
Release date:2016-06-29
Last modified:2017-08-16
Method:X-RAY DIFFRACTION (1.37 Å)
Cite:An ATP Binding Cassette Transporter Mediates the Uptake of alpha-(1,6)-Linked Dietary Oligosaccharides in Bifidobacterium and Correlates with Competitive Growth on These Substrates.
J. Biol. Chem., 291, 2016
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