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6Q2V
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BU of 6q2v by Molmil
Crystal structure of SPOC domain of human PHD-finger protein 3 (PHF3)
Descriptor: GLYCEROL, PHD finger protein 3
Authors:Grishkovskaya, I, Slade, D, Djinovic-Carugo, K.
Deposit date:2018-12-03
Release date:2020-07-15
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (2.594 Å)
Cite:PHF3 regulates neuronal gene expression through the Pol II CTD reader domain SPOC
Nat Commun, 12, 2021
6Q5Y
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BU of 6q5y by Molmil
Crystal structure of the SPOC domain of human PHF3 in complex with RNA polymerase II CTD diheptapeptide phosphorylated on Ser2Ser5
Descriptor: PHD finger protein 3, pSer2pSer5
Authors:Grishkovskaya, I, Djinovic-Carugo, K, Slade, D.
Deposit date:2018-12-09
Release date:2020-07-15
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:PHF3 regulates neuronal gene expression through the Pol II CTD reader domain SPOC
Nat Commun, 12, 2021
6IC9
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BU of 6ic9 by Molmil
Crystal structure of the SPOC domain of human PHF3 in complex with RNA polymerase II CTD diheptapeptide phosphorylated on Ser2Ser7
Descriptor: PHD finger protein 3, TYR-SEP-PRO-THR-SER-PRO-SEP-TYR-SEP-PRO-THR-SER-PRO
Authors:Grishkovskaya, I, Djinovic-Carugo, K, Slade, D.
Deposit date:2018-12-03
Release date:2020-07-15
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (1.748 Å)
Cite:PHF3 regulates neuronal gene expression through the Pol II CTD reader domain SPOC
Nat Commun, 12, 2021
6IC8
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BU of 6ic8 by Molmil
Crystal structure of the SPOC domain of human PHF3 in complex with RNA polymerase II CTD diheptapeptide phosphorylated on Ser2
Descriptor: PHD finger protein 3, TYR-SEP-PRO-THR-SER-PRO-SER-TYR-SEP-PRO-THR
Authors:Grishkovskaya, I, Djinovic-Carugo, K, Slade, D.
Deposit date:2018-12-02
Release date:2020-07-15
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (1.929 Å)
Cite:PHF3 regulates neuronal gene expression through the Pol II CTD reader domain SPOC
Nat Commun, 12, 2021
5MAV
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BU of 5mav by Molmil
Crystal structure of human PCNA in complex with PARG (poly(ADP-ribose) glycohydrolase) peptide.
Descriptor: Poly (ADP-ribose) glycohydrolase, Proliferating cell nuclear antigen
Authors:Grishkovskaya, I, Djinovic-Carugo, K, Slade, D.
Deposit date:2016-11-06
Release date:2017-08-02
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.575 Å)
Cite:A novel non-canonical PIP-box mediates PARG interaction with PCNA.
Nucleic Acids Res., 45, 2017
7Z27
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BU of 7z27 by Molmil
Crystal structure of the SPOC domain of human RBM15
Descriptor: RNA-binding protein 15
Authors:Grishkovskaya, I, Appel, L.M, Djinovic-Carugo, K, Slade, D.
Deposit date:2022-02-25
Release date:2022-12-07
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:The SPOC domain is a phosphoserine binding module that bridges transcription machinery with co- and post-transcriptional regulators.
Nat Commun, 14, 2023
7Z1K
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BU of 7z1k by Molmil
Crystal structure of the SPOC domain of human SHARP (SPEN) in complex with RNA polymerase II CTD heptapeptide phosphorylated on Ser5
Descriptor: Msx2-interacting protein, SER-TYR-SER-PRO-THR-SEP
Authors:Appel, L, Grishkovskaya, I, Slade, D, Djinovic-Carugo, K.
Deposit date:2022-02-24
Release date:2022-12-07
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:The SPOC domain is a phosphoserine binding module that bridges transcription machinery with co- and post-transcriptional regulators.
Nat Commun, 14, 2023
3SII
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BU of 3sii by Molmil
The X-ray crystal structure of poly(ADP-ribose) glycohydrolase bound to the inhibitor ADP-HPD from Thermomonospora curvata
Descriptor: 5'-O-[(S)-{[(S)-{[(2R,3R,4S)-3,4-DIHYDROXYPYRROLIDIN-2-YL]METHOXY}(HYDROXY)PHOSPHORYL]OXY}(HYDROXY)PHOSPHORYL]ADENOSINE, poly(ADP-ribose) glycohydrolase
Authors:Dunstan, M.S, Leys, D.
Deposit date:2011-06-18
Release date:2011-08-24
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:The structure and catalytic mechanism of a poly(ADP-ribose) glycohydrolase.
Nature, 477, 2011
3SIH
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BU of 3sih by Molmil
The X-ray crystal structure of poly(ADP-ribose) glycohydrolase (PARG) from Thermomonospora curvata
Descriptor: poly(ADP-ribose) glycohydrolase
Authors:Dunstan, M.S, Leys, D.
Deposit date:2011-06-18
Release date:2011-08-24
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:The structure and catalytic mechanism of a poly(ADP-ribose) glycohydrolase.
Nature, 477, 2011
3SIG
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BU of 3sig by Molmil
The X-ray crystal structure of poly(ADP-ribose) glycohydrolase (PARG) bound to ADP-ribose from Thermomonospora curvata
Descriptor: [(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL [HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL] HYDROGEN PHOSPHATE, poly(ADP-ribose) glycohydrolase
Authors:Leys, D, Dunstan, M.S.
Deposit date:2011-06-18
Release date:2011-08-24
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.28 Å)
Cite:The structure and catalytic mechanism of a poly(ADP-ribose) glycohydrolase.
Nature, 477, 2011
3SIJ
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BU of 3sij by Molmil
The X-ray crystal structure of poly(ADP-ribose) glycohydrolase E115A mutant from Thermomonospora curvata
Descriptor: poly(ADP-ribose) glycohydrolase
Authors:Dunstan, M.S, Leys, D.
Deposit date:2011-06-18
Release date:2011-08-24
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The structure and catalytic mechanism of a poly(ADP-ribose) glycohydrolase.
Nature, 477, 2011
2X47
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BU of 2x47 by Molmil
Crystal structure of human MACROD1
Descriptor: MACRO DOMAIN-CONTAINING PROTEIN 1, SULFATE ION
Authors:Vollmar, M, Phillips, C, Mehrotra, P.V, Ahel, I, Krojer, T, Yue, W, Ugochukwu, E, von Delft, F, Bountra, C, Arrowsmith, C.H, Weigelt, J, Edwards, A, Gileadi, O.
Deposit date:2010-01-28
Release date:2010-03-02
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Identification of Macro Domain Proteins as Novel O-Acetyl-Adp-Ribose Deacetylases.
J.Biol.Chem., 286, 2011

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