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7ZVX
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BU of 7zvx by Molmil
Crystal structure of human Annexin A2 in complex with full phosphorothioate 5-10 2'-methoxyethyl DNA gapmer antisense oligonucleotide solved at 2.4 A resolution
Descriptor: 1,2-ETHANEDIOL, 2'-methoxyethyl DNA gapmer antisense oligonucleotide, Annexin A2, ...
Authors:Hyjek-Skladanowska, M, Anderson, B, Mykhaylyk, V, Orr, C, Wagner, A, Skowronek, K, Seth, P, Nowotny, M.
Deposit date:2022-05-17
Release date:2022-09-14
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structures of annexin A2-PS DNA complexes show dominance of hydrophobic interactions in phosphorothioate binding.
Nucleic Acids Res., 51, 2023
7ZVN
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BU of 7zvn by Molmil
Crystal structure of human Annexin A2 in complex with full phosphorothioate 5-10 2'-methoxyethyl DNA gapmer antisense oligonucleotide solved at 1.87 A resolution
Descriptor: 2'-methoxyethyl DNA gapmer antisense oligonucleotide, Annexin A2, CALCIUM ION, ...
Authors:Hyjek-Skladanowska, M, Anderson, B, Mykhaylyk, V, Orr, C, Wagner, A, Skowronek, K, Seth, P, Nowotny, M.
Deposit date:2022-05-16
Release date:2022-09-14
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:Structures of annexin A2-PS DNA complexes show dominance of hydrophobic interactions in phosphorothioate binding.
Nucleic Acids Res., 51, 2023
4KYW
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BU of 4kyw by Molmil
Restriction endonuclease DPNI in complex with two DNA molecules
Descriptor: 5'-(*DC*DTP*DGP*DGP*6MAP*DTP*DCP*DCP*DAP*DG)-3', CALCIUM ION, SODIUM ION, ...
Authors:Mierzejewska, K, Siwek, W, Czapinska, H, Skowronek, K, Bujnicki, J.M, Bochtler, M.
Deposit date:2013-05-29
Release date:2014-06-04
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structural basis of the methylation specificity of R.DpnI.
Nucleic Acids Res., 42, 2014
4ESJ
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BU of 4esj by Molmil
RESTRICTION ENDONUCLEASE DpnI IN COMPLEX WITH TARGET DNA
Descriptor: AZIDE ION, DNA (5'-D(*CP*TP*GP*GP*(6MA)P*TP*CP*CP*AP*G)-3'), GLYCEROL, ...
Authors:Siwek, W, Czapinska, H, Bochtler, M, Bujnicki, J.M, Skowronek, K.
Deposit date:2012-04-23
Release date:2012-06-13
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Crystal structure and mechanism of action of the N6-methyladenine-dependent type IIM restriction endonuclease R.DpnI.
Nucleic Acids Res., 40, 2012
1XJ0
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BU of 1xj0 by Molmil
Crystal Structure of the GDP-bound form of the RasG60A mutant
Descriptor: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Transforming protein p21/H-Ras-1
Authors:Nassar, N, Skowronek, K.
Deposit date:2004-09-22
Release date:2005-05-10
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure of an intermediate for nucleotide exchange by Ras
To be Published
8AB0
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BU of 8ab0 by Molmil
Complex of RecO-RecR-DNA from Thermus thermophilus.
Descriptor: DNA repair protein RecO, Oligo1, Oligo2, ...
Authors:Nirwal, S, Czarnocki-Cieciura, M, Chaudhary, A, Zajko, W, Skowronek, K, Chamera, S, Figiel, M, Nowotny, M.
Deposit date:2022-07-04
Release date:2023-04-26
Last modified:2023-05-31
Method:ELECTRON MICROSCOPY (6.09 Å)
Cite:Mechanism of RecF-RecO-RecR cooperation in bacterial homologous recombination.
Nat.Struct.Mol.Biol., 30, 2023
8A8J
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BU of 8a8j by Molmil
Complex of RecF and DNA from Thermus thermophilus.
Descriptor: DNA replication and repair protein RecF, MAGNESIUM ION, Oligo1, ...
Authors:Nirwal, S, Czarnocki-Cieciura, M, Chaudhary, A, Zajko, W, Skowronek, K, Chamera, S, Figiel, M, Nowotny, M.
Deposit date:2022-06-23
Release date:2023-04-26
Last modified:2023-05-31
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Mechanism of RecF-RecO-RecR cooperation in bacterial homologous recombination.
Nat.Struct.Mol.Biol., 30, 2023
8A93
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BU of 8a93 by Molmil
Complex of RecF-RecR-DNA from Thermus thermophilus.
Descriptor: DNA replication and repair protein RecF, MAGNESIUM ION, Oligo1, ...
Authors:Nirwal, S, Czarnocki-Cieciura, M, Chaudhary, A, Zajko, W, Skowronek, K, Chamera, S, Figiel, M, Nowotny, M.
Deposit date:2022-06-27
Release date:2023-04-26
Last modified:2023-05-31
Method:ELECTRON MICROSCOPY (3.05 Å)
Cite:Mechanism of RecF-RecO-RecR cooperation in bacterial homologous recombination.
Nat.Struct.Mol.Biol., 30, 2023
8BPR
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BU of 8bpr by Molmil
Complex of RecF-RecO-RecR-DNA from Thermus thermophilus (low resolution reconstruction).
Descriptor: DNA repair protein RecO, DNA replication and repair protein RecF, MAGNESIUM ION, ...
Authors:Nirwal, S, Czarnocki-Cieciura, M, Chaudhary, A, Zajko, W, Skowronek, K, Chamera, S, Figiel, M, Nowotny, M.
Deposit date:2022-11-17
Release date:2023-04-26
Last modified:2023-05-31
Method:ELECTRON MICROSCOPY (3.65 Å)
Cite:Mechanism of RecF-RecO-RecR cooperation in bacterial homologous recombination.
Nat.Struct.Mol.Biol., 30, 2023
8BV8
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BU of 8bv8 by Molmil
Crystal structure of the phage Mu protein Mom inactive mutant S124A
Descriptor: Methylcarbamoylase mom
Authors:Silva, R.M.B, Slyvka, A, Lee, Y.J, Guan, C, Lund, S.R, Raleigh, E.A, Skowronek, K, Bochtler, M, Weigele, P.R.
Deposit date:2022-12-08
Release date:2023-12-20
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Crystal structure of the phage Mu protein Mom catalytic mutant S124A
To Be Published
6QM2
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BU of 6qm2 by Molmil
NlaIV restriction endonuclease
Descriptor: POTASSIUM ION, SODIUM ION, Type-2 restriction enzyme NlaIV
Authors:Czapinska, H, Siwek, W, Szczepanowski, R.H, Bujnicki, J.M, Bochtler, M, Skowronek, K.
Deposit date:2019-02-01
Release date:2019-05-01
Last modified:2019-06-05
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal Structure and Directed Evolution of Specificity of NlaIV Restriction Endonuclease.
J.Mol.Biol., 431, 2019
7O24
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BU of 7o24 by Molmil
Structure of the foamy viral protease-reverse transcriptase in complex with dsDNA.
Descriptor: DNA (5'-D(*AP*AP*CP*AP*GP*AP*GP*TP*GP*CP*GP*AP*CP*AP*CP*CP*TP*GP*AP*TP*TP*CP*CP*A)-3'), DNA (5'-D(*TP*GP*GP*AP*AP*TP*CP*AP*GP*GP*TP*GP*TP*CP*GP*CP*AP*CP*TP*CP*TP*G)-3'), Pr125Pol
Authors:Nowotny, M, Czarnocki-Cieciura, M.
Deposit date:2021-03-30
Release date:2021-06-30
Last modified:2022-01-19
Method:ELECTRON MICROSCOPY (4.8 Å)
Cite:Structures of Substrate Complexes of Foamy Viral Protease-Reverse Transcriptase.
J.Virol., 95, 2021
8AUP
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BU of 8aup by Molmil
Structure of hARG1 with a novel inhibitor.
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-[(1~{R},3~{R},4~{S})-3-azanyl-3-carboxy-4-[(dimethylamino)methyl]cyclohexyl]ethyl-$l^{3}-oxidanyl-bis(oxidanyl)boron, Arginase-1, ...
Authors:Napiorkowska-Gromadzka, A, Nowak, E, Nowotny, M.
Deposit date:2022-08-25
Release date:2023-03-29
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.17 Å)
Cite:Arginase 1/2 Inhibitor OATD-02: From Discovery to First-in-man Setup in Cancer Immunotherapy.
Mol.Cancer Ther., 22, 2023
4OUN
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BU of 4oun by Molmil
Crystal Structure of Mini-ribonuclease 3 from Bacillus subtilis
Descriptor: Mini-ribonuclease 3
Authors:Chojnowski, G, Czarnecka, J, Nowak, E, Pianka, D, Glow, D, Sabala, I, Skowronek, K, Nowotny, M, Bujnicki, J.M.
Deposit date:2014-02-18
Release date:2015-02-04
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Sequence-specific cleavage of dsRNA by Mini-III RNase
Nucleic Acids Res., 43, 2015
3PIH
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BU of 3pih by Molmil
T. maritima UvrA in complex with fluorescein-modified DNA
Descriptor: DNA (32-MER), PYROPHOSPHATE, UvrABC system protein A, ...
Authors:Jaciuk, M, Nowak, E, Nowotny, M.
Deposit date:2010-11-06
Release date:2011-01-19
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structure of UvrA nucleotide excision repair protein in complex with modified DNA.
Nat.Struct.Mol.Biol., 18, 2011
7Z0Z
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BU of 7z0z by Molmil
Abortive infection DNA polymerase AbiK from Lactococcus lactis, Y44F variant
Descriptor: AbiK
Authors:Figiel, M, Gapinska, M, Czarnocki-Cieciura, M, Zajko, W, Nowotny, M.
Deposit date:2022-02-24
Release date:2022-09-07
Last modified:2022-10-05
Method:ELECTRON MICROSCOPY (2.68 Å)
Cite:Mechanism of protein-primed template-independent DNA synthesis by Abi polymerases.
Nucleic Acids Res., 50, 2022
7O0H
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BU of 7o0h by Molmil
Structure of the foamy viral protease-reverse transcriptase dRH in complex with ds DNA.
Descriptor: DNA (5'-D(*AP*AP*CP*AP*GP*AP*GP*TP*GP*CP*GP*AP*CP*AP*C)-3'), DNA (5'-D(*GP*TP*GP*TP*CP*GP*CP*AP*CP*TP*CP*TP*G)-3'), Pr125Pol
Authors:Nowak, E, Nowacka, M, Nowotny, M.
Deposit date:2021-03-26
Release date:2021-06-30
Last modified:2022-01-19
Method:X-RAY DIFFRACTION (3.09 Å)
Cite:Structures of Substrate Complexes of Foamy Viral Protease-Reverse Transcriptase.
J.Virol., 95, 2021
7O0G
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BU of 7o0g by Molmil
Structure of the foamy viral protease-reverse transcriptase in complex with RNA/DNA hybrid.
Descriptor: DNA (5'-D(*CP*CP*TP*CP*TP*CP*CP*TP*GP*GP*AP*CP*AP*AP*G)-3'), Pr125Pol, RNA (5'-R(*UP*UP*CP*UP*UP*GP*UP*CP*CP*AP*GP*GP*AP*GP*AP*GP*G)-3')
Authors:Nowak, E, Nowacka, M, Nowotny, M.
Deposit date:2021-03-26
Release date:2021-06-30
Last modified:2022-01-19
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structures of Substrate Complexes of Foamy Viral Protease-Reverse Transcriptase.
J.Virol., 95, 2021
7R08
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BU of 7r08 by Molmil
Abortive infection DNA polymerase Abi-P2
Descriptor: Reverse transcriptase
Authors:Gapinska, M.A, Figiel, M, Czarnocki Cieciura, M, Nowotny, M, Zajko, W.
Deposit date:2022-02-01
Release date:2022-09-07
Last modified:2022-10-05
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Mechanism of protein-primed template-independent DNA synthesis by Abi polymerases.
Nucleic Acids Res., 50, 2022
7R07
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BU of 7r07 by Molmil
Abortive infection DNA polymerase AbiK from Lactococcus lactis
Descriptor: AbiK, DNA (5'-D(*CP*CP*CP*CP*CP*CP*CP*CP*CP*CP*C)-3'), MAGNESIUM ION
Authors:Figiel, M, Gapinska, M, Czarnocki-Cieciura, M, Zajko, W, Nowotny, M.
Deposit date:2022-02-01
Release date:2022-09-07
Last modified:2022-10-05
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Mechanism of protein-primed template-independent DNA synthesis by Abi polymerases.
Nucleic Acids Res., 50, 2022
7R06
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BU of 7r06 by Molmil
Abortive infection DNA polymerase AbiK from Lactococcus lactis
Descriptor: AbiK, DNA (5'-D(*CP*CP*CP*CP*CP*CP*CP*CP*CP*CP*CP*C)-3')
Authors:Figiel, M, Nowotny, M, Gapinska, M, Czarnocki-Cieciura, M, Zajko, W.
Deposit date:2022-02-01
Release date:2022-09-07
Last modified:2022-10-05
Method:ELECTRON MICROSCOPY (2.27 Å)
Cite:Mechanism of protein-primed template-independent DNA synthesis by Abi polymerases.
Nucleic Acids Res., 50, 2022

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