Author results

4P2S
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ALANINE SCANNING MUTAGENESIS IDENTIFIES AN ASPARAGINE-ARGININE-LYSINE TRIAD ESSENTIAL TO ASSEMBLY OF THE SHELL OF THE PDU MICROCOMPARTMENT
Descriptor:Putative propanediol utilization protein PduA, SULFATE ION, GLYCEROL, ...
Authors:Sinha, S., Cheng, S., Sung, Y.W., McNamara, D.E., Sawaya, M.R., Yeates, T.O., Bobik, T.A.
Deposit date:2014-03-03
Release date:2014-05-14
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Alanine Scanning Mutagenesis Identifies an Asparagine-Arginine-Lysine Triad Essential to Assembly of the Shell of the Pdu Microcompartment.
J.Mol.Biol., 426, 2014
5XO3
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THANATIN M21F FREE
Descriptor:Thanatin
Authors:Sinha, S., Bhattacharjya, S.
Deposit date:2017-05-26
Release date:2018-06-27
Method:SOLUTION NMR
Cite:Thanatin M21F Free
To Be Published
5XO4
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FREE THANATIN AT 298K
Descriptor:Thanatin
Authors:Sinha, S., Bhattacharjya, S.
Deposit date:2017-05-26
Release date:2018-06-27
Method:SOLUTION NMR
Cite:Free Thanatin at 298K
To Be Published
5XO5
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FREE THANATIN Y10A M21A
Descriptor:Thanatin
Authors:Sinha, S., Bhattacharjya, S.
Deposit date:2017-05-26
Release date:2018-06-27
Method:SOLUTION NMR
Cite:Free Thanatin Y10AM21A
To Be Published
5XO9
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THANATIN IN PRESENCE OF LPS
Descriptor:Thanatin
Authors:Sinha, S., Bhattacharjya, S.
Deposit date:2017-05-27
Release date:2018-06-27
Method:SOLUTION NMR
Cite:Thanatin in presence of LPS
To Be Published
5XOA
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THANATIN M21F IN COMPLEX WITH LPS
Descriptor:Thanatin
Authors:Sinha, S., Bhattacharyya, S.
Deposit date:2017-05-27
Release date:2018-06-27
Method:SOLUTION NMR
Cite:Thanatin M21F in complex with LPS
To Be Published
5XOK
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THANATIN Y10M21AA IN COMPLEX WITH LPS
Descriptor:Thanatin
Authors:Sinha, S., Bhattacharjya, S.
Deposit date:2017-05-29
Release date:2018-07-04
Method:SOLUTION NMR
Cite:Thanatin Y10M21AA in complex with LPS
To Be Published
5XOL
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THANATIN R13R14AA IN COMPLEX WITH LPS
Descriptor:Thanatin
Authors:Sinha, S., Bhattacharjya, S.
Deposit date:2017-05-29
Release date:2018-07-04
Method:SOLUTION NMR
Cite:Thanatin R13R14AA in complex with LPS
To Be Published
6A8Y
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YR26_SDS
Descriptor:YR26_SDS
Authors:Sinha, S., Bhattacharjya, S.
Deposit date:2018-07-11
Release date:2019-07-17
Method:SOLUTION NMR
Cite:YR26_SDS
To Be Published
6AAB
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THANATIN IN PRESENCE OF DPC
Descriptor:Thanatin
Authors:Sinha, S., Bhattacharjya, S.
Deposit date:2018-07-18
Release date:2019-07-24
Method:SOLUTION NMR
Cite:Thanatin in presence of DPC
To Be Published
3DVU
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CRYSTAL STRUCTURE OF THE COMPLEX OF MURINE GAMMA-HERPESVIRUS 68 BCL-2 HOMOLOG M11 AND THE BECLIN 1 BH3 DOMAIN
Descriptor:V-bcl-2, Beclin-1
Authors:Sinha, S.
Deposit date:2008-07-20
Release date:2008-10-07
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Molecular basis of the regulation of Beclin 1-dependent autophagy by the gamma-herpesvirus 68 Bcl-2 homolog M11
Autophagy, 4, 2008
1QD9
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BACILLUS SUBTILIS YABJ
Descriptor:PURINE REGULATORY PROTEIN YABJ, MERCURY (II) ION, ACETIC ACID, ...
Authors:Smith, J.L., Sinha, S., Rappu, P., Lange, S.C., Mantsala, P., Zalkin, H.
Deposit date:1999-07-09
Release date:1999-11-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure of Bacillus subtilis YabJ, a purine regulatory protein and member of the highly conserved YjgF family.
Proc.Natl.Acad.Sci.USA, 96, 1999
2D3S
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CRYSTAL STRUCTURE OF BASIC WINGED BEAN LECTIN WITH TN-ANTIGEN
Descriptor:Basic agglutinin, N-ACETYL-D-GLUCOSAMINE, ALPHA-L-FUCOSE, ...
Authors:Kulkarni, K.A., Sinha, S., Katiyar, S., Surolia, A., Vijayan, M., Suguna, K.
Deposit date:2005-10-01
Release date:2006-01-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structural basis for the specificity of basic winged bean lectin for the Tn-antigen: a crystallographic, thermodynamic and modelling study
Febs Lett., 579, 2005
6AFQ
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THANATIN M21F IN PRESENCE OF DPC
Descriptor:Thanatin
Authors:Bhattacharjya, S., Sinha, S.
Deposit date:2018-08-08
Release date:2019-08-14
Method:SOLUTION NMR
Cite:Thanatin M21F in presence of DPC
To Be Published
4MI8
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CRYSTAL STRUCTURE OF THE COMPLEX OF MURINE GAMMA-HERPESVIRUS 68 BCL-2 HOMOLOG M11 AND A BECLIN 1 BH3 DOMAIN-DERIVED PEPTIDE
Descriptor:Bcl-2 homolog (Gene 16?), Beclin-1, SULFATE ION
Authors:Su, M., Mei, Y., Sinha, S.
Deposit date:2013-08-30
Release date:2014-01-29
Last modified:2016-02-17
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Targeting gamma-herpesvirus 68 Bcl-2-mediated down-regulation of autophagy.
J.Biol.Chem., 289, 2014
5EFM
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BECLIN 1 FLEXIBLE-HELICAL DOMIAN (FHD) (141-171)
Descriptor:Beclin-1, SULFATE ION
Authors:Sinha, S., Mei, Y.
Deposit date:2015-10-23
Release date:2016-07-20
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Conformational Flexibility Enables the Function of a BECN1 Region Essential for Starvation-Mediated Autophagy.
Biochemistry, 55, 2016
4PPD
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PDUA K26A, CRYSTAL FORM 2
Descriptor:Propanediol utilization protein PduA, SULFATE ION, GLYCEROL
Authors:McNamara, D.E., Sawaya, M.R., Bobik, T.A., Yeates, T.O.
Deposit date:2014-02-26
Release date:2014-05-14
Last modified:2014-06-04
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Alanine scanning mutagenesis identifies an asparagine-arginine-lysine triad essential to assembly of the shell of the pdu microcompartment.
J.Mol.Biol., 426, 2014
5K7B
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BECLIN 2 CCD HOMODIMER
Descriptor:Beclin-2
Authors:Su, M., Sinha, S.
Deposit date:2016-05-25
Release date:2017-03-08
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:BECN2 interacts with ATG14 through a metastable coiled-coil to mediate autophagy.
Protein Sci., 26, 2017
5K9L
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BECLIN 2 CCD N187L MUTANT HOMODIMER
Descriptor:Beclin-2
Authors:Su, M., Sinha, S.
Deposit date:2016-06-01
Release date:2017-03-08
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2.52 Å)
Cite:BECN2 interacts with ATG14 through a metastable coiled-coil to mediate autophagy.
Protein Sci., 26, 2017
5HHE
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HUMAN BECLIN 1 COILED-COIL DOMAIN
Descriptor:Beclin-1
Authors:Mei, Y., Sinha, S.
Deposit date:2016-01-10
Release date:2016-07-20
Last modified:2016-08-31
Method:X-RAY DIFFRACTION (1.46 Å)
Cite:Identification of BECN1 and ATG14 Coiled-Coil Interface Residues That Are Important for Starvation-Induced Autophagy.
Biochemistry, 55, 2016
3NSH
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BACE-1 IN COMPLEX WITH ELN475957
Descriptor:Beta-secretase 1, N-[(1S,2R)-1-(3,5-difluorobenzyl)-3-({1-[4-(2,2-dimethylpropyl)thiophen-2-yl]cyclopropyl}amino)-2-hydroxypropyl]acetamide
Authors:Probst, G.D., Bowers, S., Sealy, J.M., Brecht, E., Yao, N.
Deposit date:2010-07-01
Release date:2010-09-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Design and synthesis of hydroxyethylamine (HEA) BACE-1 inhibitors: structure-activity relationship of the aryl region.
Bioorg.Med.Chem.Lett., 20, 2010
4RBT
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PDUA K26A S40L MUTANT, FROM SALMONELLA ENTERICA SEROVAR TYPHIMURIUM LT2
Descriptor:Propanediol utilization protein PduA, SULFATE ION
Authors:Chun, S., Sawaya, M.R., Yeates, T.O.
Deposit date:2014-09-12
Release date:2015-02-18
Last modified:2015-03-25
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Selective molecular transport through the protein shell of a bacterial microcompartment organelle.
Proc.Natl.Acad.Sci.USA, 112, 2015
4RBU
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PDUA K26A S40Q MUTANT, FROM SALMONELLA ENTERICA SEROVAR TYPHIMURIUM LT2
Descriptor:Propanediol utilization protein PduA, SULFATE ION
Authors:Chun, S., Sawaya, M.R., Yeates, T.O.
Deposit date:2014-09-13
Release date:2015-02-18
Last modified:2015-03-25
Method:X-RAY DIFFRACTION (2.79 Å)
Cite:Selective molecular transport through the protein shell of a bacterial microcompartment organelle.
Proc.Natl.Acad.Sci.USA, 112, 2015
4RBV
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PDUA K26A S40GSG MUTANT, FROM SALMONELLA ENTERICA SEROVAR TYPHIMURIUM LT2
Descriptor:Propanediol utilization protein PduA, SULFATE ION
Authors:Chun, S., Sawaya, M.R., Yeates, T.O.
Deposit date:2014-09-13
Release date:2015-02-18
Last modified:2015-03-25
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Selective molecular transport through the protein shell of a bacterial microcompartment organelle.
Proc.Natl.Acad.Sci.USA, 112, 2015
2IQG
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CRYSTAL STRUCTURE OF HYDROXYETHYL SECONDARY AMINE-BASED PEPTIDOMIMETIC INHIBITOR OF HUMAN BETA-SECRETASE (BACE)
Descriptor:Beta-secretase 1, N'-{(1S,2R)-1-(3,5-DIFLUOROBENZYL)-2-HYDROXY-3-[(3-IODOBENZYL)AMINO]PROPYL}-5-METHYL-N,N-DIPROPYLISOPHTHALAMIDE
Authors:Benson, T.E., Woods, D.D., Prince, D.B., Tomasselli, A.G., Emmons, T.L.
Deposit date:2006-10-13
Release date:2007-02-27
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Design, Synthesis, and Crystal Structure of Hydroxyethyl Secondary Amine-Based Peptidomimetic Inhibitors of Human beta-Secretase.
J.Med.Chem., 50, 2007
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