Author results

1JBE
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1.08 A STRUCTURE OF APO-CHEY REVEALS META-ACTIVE CONFORMATION
Descriptor:Chemotaxis protein CHEY, SULFATE ION, GLYCEROL
Authors:Simonovic, M., Volz, K.
Deposit date:2001-06-04
Release date:2001-08-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.08 Å)
Cite:A distinct meta-active conformation in the 1.1-A resolution structure of wild-type ApoCheY.
J.Biol.Chem., 276, 2001
1M93
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1.65 A STRUCTURE OF CLEAVED VIRAL SERPIN CRMA
Descriptor:Serine proteinase inhibitor 2, PHOSPHATE ION
Authors:Simonovic, M., Gettins, P.G.W., Volz, K.
Deposit date:2002-07-26
Release date:2003-08-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Crystal structure of viral serpin crmA provides insights into its mechanism of cysteine proteinase inhibition
Protein Sci., 9, 2000
1C8O
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2.9 A STRUCTURE OF CLEAVED VIRAL SERPIN CRMA
Descriptor:ICE INHIBITOR
Authors:Simonovic, M., Gettins, P.G.W., Volz, K.
Deposit date:2000-06-01
Release date:2000-09-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structure of viral serpin crmA provides insights into its mechanism of cysteine proteinase inhibition.
Protein Sci., 9, 2000
1IMV
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2.85 A CRYSTAL STRUCTURE OF PEDF
Descriptor:PIGMENT EPITHELIUM-DERIVED FACTOR, N-ACETYL-D-GLUCOSAMINE
Authors:Simonovic, M., Gettins, P.G.W., Volz, K.
Deposit date:2001-05-11
Release date:2001-09-26
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Crystal structure of human PEDF, a potent anti-angiogenic and neurite growth-promoting factor.
Proc.Natl.Acad.Sci.USA, 98, 2001
1J8E
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CRYSTAL STRUCTURE OF LIGAND-BINDING REPEAT CR7 FROM LRP
Descriptor:LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 1, CALCIUM ION
Authors:Simonovic, M., Dolmer, K., Huang, W., Strickland, D.K., Volz, K., Gettins, P.G.W.
Deposit date:2001-05-21
Release date:2001-12-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Calcium coordination and pH dependence of the calcium affinity of ligand-binding repeat CR7 from the LRP. Comparison with related domains from the LRP and the LDL receptor.
Biochemistry, 40, 2001
2FOT
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CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN CALMODULIN AND ALPHAII-SPECTRIN
Descriptor:Calmodulin, alpha-II spectrin Spectrin, CALCIUM ION
Authors:Simonovic, M., Zhang, Z., Cianci, C.D., Steitz, T.A., Morrow, J.S.
Deposit date:2006-01-13
Release date:2006-09-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Structure of the calmodulin alphaII-spectrin complex provides insight into the regulation of cell plasticity.
J.Biol.Chem., 281, 2006
3CMA
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THE STRUCTURE OF CCA AND CCA-PHE-CAP-BIO BOUND TO THE LARGE RIBOSOMAL SUBUNIT OF HALOARCULA MARISMORTUI
Descriptor:50S ribosomal protein L2P, 50S ribosomal protein L3P, 50S ribosomal protein L4P, ...
Authors:Simonovic, M., Steitz, T.A.
Deposit date:2008-03-21
Release date:2008-09-23
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Peptidyl-CCA deacylation on the ribosome promoted by induced fit and the O3'-hydroxyl group of A76 of the unacylated A-site tRNA.
Rna, 14, 2008
3CME
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THE STRUCTURE OF CA AND CCA-PHE-CAP-BIO BOUND TO THE LARGE RIBOSOMAL SUBUNIT OF HALOARCULA MARISMORTUI
Descriptor:50S ribosomal protein L2P, 50S ribosomal protein L3P, 50S ribosomal protein L4P, ...
Authors:Simonovic, M., Steitz, T.A.
Deposit date:2008-03-21
Release date:2008-09-23
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Peptidyl-CCA deacylation on the ribosome promoted by induced fit and the O3'-hydroxyl group of A76 of the unacylated A-site tRNA.
Rna, 14, 2008
3EDU
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CRYSTAL STRUCTURE OF THE ANKYRIN-BINDING DOMAIN OF HUMAN ERYTHROID SPECTRIN
Descriptor:Spectrin beta chain, erythrocyte
Authors:Simonovic, M., Stabach, P., Simonovic, I., Steitz, T.A., Morrow, J.S.
Deposit date:2008-09-03
Release date:2009-02-10
Last modified:2011-07-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The structure of the ankyrin-binding site of {beta}-spectrin reveals how tandem spectrin-repeats generate unique ligand-binding properties
Blood, 113, 2009
3UGQ
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CRYSTAL STRUCTURE OF THE APO FORM OF THE YEAST MITOCHONDRIAL THREONYL-TRNA SYNTHETASE DETERMINED AT 2.1 ANGSTROM RESOLUTION
Descriptor:Threonyl-tRNA synthetase, mitochondrial, ZINC ION, ...
Authors:Peterson, K.M., Ling, J., Simonovic, I., Cho, C., Soll, D., Simonovic, M.
Deposit date:2011-11-02
Release date:2012-02-22
Last modified:2014-11-12
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Yeast mitochondrial threonyl-tRNA synthetase recognizes tRNA isoacceptors by distinct mechanisms and promotes CUN codon reassignment.
Proc.Natl.Acad.Sci.USA, 109, 2012
3UGT
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CRYSTAL STRUCTURE OF THE YEAST MITOCHONDRIAL THREONYL-TRNA SYNTHETASE - ORTHORHOMBIC CRYSTAL FORM
Descriptor:Threonyl-tRNA synthetase, mitochondrial, ZINC ION
Authors:Peterson, K.M., Ling, J., Simonovic, I., Cho, C., Soll, D., Simonovic, M.
Deposit date:2011-11-02
Release date:2012-02-22
Last modified:2014-11-12
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Yeast mitochondrial threonyl-tRNA synthetase recognizes tRNA isoacceptors by distinct mechanisms and promotes CUN codon reassignment.
Proc.Natl.Acad.Sci.USA, 109, 2012
3UH0
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CRYSTAL STRUCTURE OF THE YEAST MITOCHONDRIAL THREONYL-TRNA SYNTHETASE (MST1) IN COMPLEX WITH THREONYL SULFAMOYL ADENYLATE
Descriptor:Threonyl-tRNA synthetase, mitochondrial, ZINC ION, ...
Authors:Peterson, K.M., Ling, J., Simonovic, I., Cho, C., Soll, D., Simonovic, M.
Deposit date:2011-11-03
Release date:2012-02-22
Last modified:2012-06-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:Yeast mitochondrial threonyl-tRNA synthetase recognizes tRNA isoacceptors by distinct mechanisms and promotes CUN codon reassignment.
Proc.Natl.Acad.Sci.USA, 109, 2012
4EO4
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CRYSTAL STRUCTURE OF THE YEAST MITOCHONDRIAL THREONYL-TRNA SYNTHETASE (MST1) IN COMPLEX WITH SERYL SULFAMOYL ADENYLATE
Descriptor:Threonine--tRNA ligase, mitochondrial, 5'-O-(N-(L-SERYL)-SULFAMOYL)ADENOSINE, ...
Authors:Peterson, K.M., Ling, J., Simonovic, I., Soll, D., Simonovic, M.
Deposit date:2012-04-13
Release date:2012-07-11
Last modified:2013-01-02
Method:X-RAY DIFFRACTION (2.87 Å)
Cite:The mechanism of pre-transfer editing in yeast mitochondrial threonyl-tRNA synthetase.
J.Biol.Chem., 287, 2012
5IZK
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THE CRYSTAL STRUCTURE OF HUMAN EEFSEC IN COMPLEX WITH GDP
Descriptor:Selenocysteine-specific elongation factor, GUANOSINE-5'-DIPHOSPHATE
Authors:Dobosz-Bartoszek, M., Simonovic, M.
Deposit date:2016-03-25
Release date:2016-10-12
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:Crystal structures of the human elongation factor eEFSec suggest a non-canonical mechanism for selenocysteine incorporation.
Nat Commun, 7, 2016
5IZL
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THE CRYSTAL STRUCTURE OF HUMAN EEFSEC IN COMPLEX WITH GDPCP
Descriptor:Selenocysteine-specific elongation factor, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER
Authors:Dobosz-Bartoszek, M., Simonovic, M.
Deposit date:2016-03-25
Release date:2016-10-12
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2.72 Å)
Cite:Crystal structures of the human elongation factor eEFSec suggest a non-canonical mechanism for selenocysteine incorporation.
Nat Commun, 7, 2016
5IZM
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THE CRYSTAL STRUCTURE OF HUMAN EEFSEC IN COMPLEX WITH GDPNP
Descriptor:Selenocysteine-specific elongation factor, MANGANESE (II) ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER
Authors:Dobosz-Bartoszek, M., Otwinowski, Z., Simonovic, M.
Deposit date:2016-03-25
Release date:2016-10-12
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Crystal structures of the human elongation factor eEFSec suggest a non-canonical mechanism for selenocysteine incorporation.
Nat Commun, 7, 2016
1OO8
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CRYSTAL STRUCTURE OF A1PI-PITTSBURGH IN THE NATIVE CONFORMATION
Descriptor:Alpha-1-antitrypsin precursor
Authors:Dementiev, A., Simonovic, M., Volz, K., Gettins, P.G.
Deposit date:2003-03-03
Release date:2003-08-05
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Canonical inhibitor-like interactions explain reactivity of alpha1-proteinase inhibitor Pittsburgh and antithrombin with proteinases
J.Biol.Chem., 278, 2003
1OPH
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NON-COVALENT COMPLEX BETWEEN ALPHA-1-PI-PITTSBURGH AND S195A TRYPSIN
Descriptor:Alpha-1-antitrypsin precursor, Trypsinogen, cationic precursor
Authors:Dementiev, A., Simonovic, M., Volz, K., Gettins, P.G.
Deposit date:2003-03-05
Release date:2003-08-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Canonical inhibitor-like interactions explain reactivity of alpha1-proteinase inhibitor Pittsburgh and antithrombin with proteinases
J.Biol.Chem., 278, 2003
3HL2
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THE CRYSTAL STRUCTURE OF THE HUMAN SEPSECS-TRNASEC COMPLEX
Descriptor:O-phosphoseryl-tRNA(Sec) selenium transferase, tRNASec, (5-HYDROXY-4,6-DIMETHYLPYRIDIN-3-YL)METHYL DIHYDROGEN PHOSPHATE, ...
Authors:Palioura, S., Steitz, T.A., Soll, D., Simonovic, M.
Deposit date:2009-05-26
Release date:2009-10-06
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.81 Å)
Cite:The human SepSecS-tRNASec complex reveals the mechanism of selenocysteine formation.
Science, 325, 2009
3LXO
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THE CRYSTAL STRUCTURE OF RIBONUCLEASE A IN COMPLEX WITH THYMIDINE-3'-MONOPHOSPHATE
Descriptor:Ribonuclease pancreatic, THYMIDINE-3'-PHOSPHATE
Authors:Doucet, N., Jayasundera, T.B., Simonovic, M., Loria, J.P.
Deposit date:2010-02-25
Release date:2010-04-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.549 Å)
Cite:The crystal structure of ribonuclease A in complex with thymidine-3'-monophosphate provides further insight into ligand binding.
Proteins, 78, 2010
4WYN
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THE CRYSTAL STRUCTURE OF THE A109G MUTANT OF RNASE A
Descriptor:Ribonuclease pancreatic
Authors:French, R.L., Gagne, D., Doucet, N., Simonovic, M.
Deposit date:2014-11-17
Release date:2015-11-18
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (1.805 Å)
Cite:Perturbation of the Conformational Dynamics of an Active-Site Loop Alters Enzyme Activity.
Structure, 23, 2015
4WYP
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THE CRYSTAL STRUCTURE OF THE A109G MUTANT OF RNASE A IN COMPLEX WITH 5'AMP
Descriptor:Ribonuclease pancreatic, ADENOSINE MONOPHOSPHATE
Authors:French, R.L., Gagne, D., Doucet, N., Simonovic, M.
Deposit date:2014-11-17
Release date:2015-11-18
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (1.502 Å)
Cite:Perturbation of the Conformational Dynamics of an Active-Site Loop Alters Enzyme Activity.
Structure, 23, 2015
4WYZ
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THE CRYSTAL STRUCTURE OF THE A109G MUTANT OF RNASE A IN COMPLEX WITH 3'UMP
Descriptor:Ribonuclease pancreatic, 3'-URIDINEMONOPHOSPHATE
Authors:French, R.L., Gagne, D., Doucet, N., Simonovic, M.
Deposit date:2014-11-18
Release date:2015-11-18
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (1.449 Å)
Cite:Perturbation of the Conformational Dynamics of an Active-Site Loop Alters Enzyme Activity.
Structure, 23, 2015
4YE6
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THE CRYSTAL STRUCTURE OF THE INTACT HUMAN GLNRS
Descriptor:Glutamine--tRNA ligase
Authors:Ognjenovic, J., Wu, J., Ling, J., Simonovic, M.
Deposit date:2015-02-23
Release date:2016-02-17
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The crystal structure of human GlnRS provides basis for the development of neurological disorders.
Nucleic Acids Res., 44, 2016
4YE8
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THE CRYSTAL STRUCTURE OF THE Y57H MUTANT OF HUMAN GLNRS
Descriptor:Glutamine--tRNA ligase
Authors:Ognjenovic, J., Wu, J., Ling, J., Simonovic, M.
Deposit date:2015-02-23
Release date:2016-02-17
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:The crystal structure of human GlnRS provides basis for the development of neurological disorders.
Nucleic Acids Res., 44, 2016
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