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1A28
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BU of 1a28 by Molmil
HORMONE-BOUND HUMAN PROGESTERONE RECEPTOR LIGAND-BINDING DOMAIN
Descriptor: PROGESTERONE, PROGESTERONE RECEPTOR
Authors:Sigler, P.B, Williams, S.P.
Deposit date:1998-01-19
Release date:1998-07-15
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Atomic structure of progesterone complexed with its receptor.
Nature, 393, 1998
3WRP
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BU of 3wrp by Molmil
FLEXIBILITY OF THE DNA-BINDING DOMAINS OF TRP REPRESSOR
Descriptor: TRP REPRESSOR
Authors:Zhang, R.-G, Sigler, P.B.
Deposit date:1987-12-01
Release date:1988-04-16
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Flexibility of the DNA-binding domains of trp repressor.
Proteins, 3, 1988
2OZ9
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BU of 2oz9 by Molmil
E. coli TRP holorepressor, orthorhombic crystal form
Descriptor: SODIUM ION, SULFATE ION, TRYPTOPHAN, ...
Authors:Lawson, C.L, Sigler, P.B.
Deposit date:2007-02-25
Release date:2007-03-06
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Flexibility of the DNA-binding domains of trp repressor.
Proteins, 3, 1988
1D3U
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BU of 1d3u by Molmil
TATA-BINDING PROTEIN/TRANSCRIPTION FACTOR (II)B/BRE+TATA-BOX COMPLEX FROM PYROCOCCUS WOESEI
Descriptor: DNA 23-MER: BRE+TATA-BOX, DNA 24-MER: BRE+TATA-BOX, TATA-BINDING PROTEIN, ...
Authors:Littlefield, O, Korkhin, Y, Sigler, P.B.
Deposit date:1999-10-01
Release date:1999-11-15
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The structural basis for the oriented assembly of a TBP/TFB/promoter complex.
Proc.Natl.Acad.Sci.USA, 96, 1999
7KCI
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BU of 7kci by Molmil
DETERMINANTS OF REPRESSOR/OPERATOR RECOGNITION FROM THE STRUCTURE OF THE TRP OPERATOR BINDING SITE
Descriptor: Self-complementary deoxyoligonucleotide decamer d(CCACTAGTGG)
Authors:Shakked, Z, Guzikevich-Guerstein, G, Frolow, F, Rabinovich, D, Joachimiak, A, Sigler, P.B.
Deposit date:1994-09-12
Release date:2020-10-14
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Determinants of repressor/operator recognition from the structure of the trp operator binding site.
Nature, 368, 1994
2TRC
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BU of 2trc by Molmil
PHOSDUCIN/TRANSDUCIN BETA-GAMMA COMPLEX
Descriptor: GADOLINIUM ATOM, PHOSDUCIN, TRANSDUCIN
Authors:Gaudet, R, Bohm, A, Sigler, P.B.
Deposit date:1997-01-06
Release date:1997-06-05
Last modified:2019-08-14
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure at 2.4 angstroms resolution of the complex of transducin betagamma and its regulator, phosducin.
Cell(Cambridge,Mass.), 87, 1996
1WRP
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BU of 1wrp by Molmil
FLEXIBILITY OF THE DNA-BINDING DOMAINS OF TRP REPRESSOR
Descriptor: TRP REPRESSOR, TRYPTOPHAN
Authors:Schewitz, R.W, Otwinowski, Z, Lawson, C.L, Joachimiak, A, Sigler, P.B.
Deposit date:1987-12-01
Release date:1988-04-16
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Flexibility of the DNA-binding domains of trp repressor.
Proteins, 3, 1988
2WAQ
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BU of 2waq by Molmil
The complete structure of the archaeal 13-subunit DNA-directed RNA Polymerase
Descriptor: DNA-DIRECTED RNA POLYMERASE RPO10 SUBUNIT, DNA-DIRECTED RNA POLYMERASE RPO11 SUBUNIT, DNA-DIRECTED RNA POLYMERASE RPO12 SUBUNIT, ...
Authors:Korkhin, Y, Unligil, U.M, Littlefield, O, Nelson, P.J, Stuart, D.I, Sigler, P.B, Bell, S.D, Abrescia, N.G.A.
Deposit date:2009-02-11
Release date:2009-05-19
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3.35 Å)
Cite:Evolution of complex RNA polymerases: the complete archaeal RNA polymerase structure.
Plos Biol., 7, 2009
1CF1
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BU of 1cf1 by Molmil
ARRESTIN FROM BOVINE ROD OUTER SEGMENTS
Descriptor: PROTEIN (ARRESTIN)
Authors:Hirsch, J.A, Schubert, C, Gurevich, V.V, Sigler, P.B.
Deposit date:1999-03-23
Release date:1999-04-16
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The 2.8 A crystal structure of visual arrestin: a model for arrestin's regulation.
Cell(Cambridge,Mass.), 97, 1999
1CIT
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BU of 1cit by Molmil
DNA-BINDING MECHANISM OF THE MONOMERIC ORPHAN NUCLEAR RECEPTOR NGFI-B
Descriptor: DNA (5'-D(*CP*CP*GP*AP*AP*AP*AP*GP*GP*TP*CP*AP*TP*GP*CP*G)-3'), DNA (5'-D(*CP*GP*CP*AP*TP*GP*AP*CP*CP*TP*TP*TP*TP*CP*GP*G)-3'), PROTEIN (ORPHAN NUCLEAR RECEPTOR NGFI-B), ...
Authors:Meinke, G, Sigler, P.B.
Deposit date:1999-04-05
Release date:1999-05-03
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:DNA-binding mechanism of the monomeric orphan nuclear receptor NGFI-B.
Nat.Struct.Biol., 6, 1999
1DK7
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BU of 1dk7 by Molmil
CRYSTAL STRUCTURE OF AN ISOLATED APICAL DOMAIN OF GROEL
Descriptor: GROEL
Authors:Chen, L, Sigler, P.B.
Deposit date:1999-12-06
Release date:2000-01-05
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:The crystal structure of a GroEL/peptide complex: plasticity as a basis for substrate diversity.
Cell(Cambridge,Mass.), 99, 1999
1GOT
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BU of 1got by Molmil
HETEROTRIMERIC COMPLEX OF A GT-ALPHA/GI-ALPHA CHIMERA AND THE GT-BETA-GAMMA SUBUNITS
Descriptor: GT-ALPHA/GI-ALPHA CHIMERA, GT-BETA, GT-GAMMA, ...
Authors:Lambright, D.G, Sondek, J, Bohm, A, Skiba, N.P, Hamm, H.E, Sigler, P.B.
Deposit date:1996-08-07
Release date:1997-03-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:The 2.0 A crystal structure of a heterotrimeric G protein.
Nature, 379, 1996
3C7L
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BU of 3c7l by Molmil
Molecular architecture of Galphao and the structural basis for RGS16-mediated deactivation
Descriptor: Regulator of G-protein signaling 16
Authors:Slep, K.C, Kercher, M.A, Wieland, T, Chen, C, Simon, M.I, Sigler, P.B.
Deposit date:2008-02-07
Release date:2008-05-06
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Molecular architecture of G{alpha}o and the structural basis for RGS16-mediated deactivation.
Proc.Natl.Acad.Sci.Usa, 105, 2008
3C7K
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BU of 3c7k by Molmil
Molecular architecture of Galphao and the structural basis for RGS16-mediated deactivation
Descriptor: GUANOSINE-5'-DIPHOSPHATE, Guanine nucleotide-binding protein G(o) subunit alpha, MAGNESIUM ION, ...
Authors:Slep, K.C, Kercher, M.A, Wieland, T, Chen, C, Simon, M.I, Sigler, P.B.
Deposit date:2008-02-07
Release date:2008-05-06
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Molecular architecture of G{alpha}o and the structural basis for RGS16-mediated deactivation.
Proc.Natl.Acad.Sci.Usa, 105, 2008
2WB1
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BU of 2wb1 by Molmil
The complete structure of the archaeal 13-subunit DNA-directed RNA Polymerase
Descriptor: DNA-DIRECTED RNA POLYMERASE RPO10 SUBUNIT, DNA-DIRECTED RNA POLYMERASE RPO11 SUBUNIT, DNA-DIRECTED RNA POLYMERASE RPO12 SUBUNIT, ...
Authors:Korkhin, Y, Unligil, U.M, Littlefield, O, Nelson, P.J, Stuart, D.I, Sigler, P.B, Bell, S.D, Abrescia, N.G.A.
Deposit date:2009-02-19
Release date:2009-05-19
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3.52 Å)
Cite:Evolution of Complex RNA Polymerase: The Complete Archaeal RNA Polymerase Structure
Plos Biol., 7, 2009
1C9B
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BU of 1c9b by Molmil
CRYSTAL STRUCTURE OF A HUMAN TBP CORE DOMAIN-HUMAN TFIIB CORE DOMAIN COMPLEX BOUND TO AN EXTENDED, MODIFIED ADENOVIRAL MAJOR LATE PROMOTER (ADMLP)
Descriptor: ADMLP TATA-BOX DNA CONTAINING IIB RECOGNITION ELEMENT, GENERAL TRANSCRIPTION FACTOR IIB, TATA BOX BINDING PROTEIN
Authors:Tsai, F.T.F, Sigler, P.B.
Deposit date:1999-08-01
Release date:2000-01-10
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structural basis of preinitiation complex assembly on human pol II promoters.
EMBO J., 19, 2000
2BOP
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BU of 2bop by Molmil
CRYSTAL STRUCTURE AT 1.7 ANGSTROMS OF THE BOVINE PAPILLOMAVIRUS-1 E2 DNA-BINDING DOMAIN BOUND TO ITS DNA TARGET
Descriptor: DNA (5'-D(*CP*CP*GP*AP*CP*CP*GP*AP*CP*GP*TP*CP*GP*GP*TP*CP*G )-3'), PROTEIN (E2), YTTERBIUM (III) ION
Authors:Hegde, R.S, Grossman, S.R, Laimins, L.A, Sigler, P.B.
Deposit date:1994-01-13
Release date:1994-01-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure at 1.7 A of the bovine papillomavirus-1 E2 DNA-binding domain bound to its DNA target.
Nature, 359, 1992
2NLL
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BU of 2nll by Molmil
RETINOID X RECEPTOR-THYROID HORMONE RECEPTOR DNA-BINDING DOMAIN HETERODIMER BOUND TO THYROID RESPONSE ELEMENT DNA
Descriptor: DNA (5'-D(*CP*AP*GP*GP*TP*CP*AP*TP*TP*(5IU)P*CP*AP*GP*GP*TP*CP*AP*G)-3'), DNA (5'-D(*CP*TP*GP*AP*CP*CP*TP*GP*AP*AP*AP*TP*GP*AP*CP*CP*T P*G)-3'), PROTEIN (RETINOIC ACID RECEPTOR), ...
Authors:Rastinejad, F, Perlmann, T, Evans, R.M, Sigler, P.B.
Deposit date:1996-11-20
Release date:1997-03-12
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural determinants of nuclear receptor assembly on DNA direct repeats.
Nature, 375, 1995
1B9Y
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BU of 1b9y by Molmil
STRUCTURAL ANALYSIS OF PHOSDUCIN AND ITS PHOSPHORYLATION-REGULATED INTERACTION WITH TRANSDUCIN BETA-GAMMA
Descriptor: GADOLINIUM ATOM, PROTEIN (PHOSDUCIN), PROTEIN (TRANSDUCIN)
Authors:Gaudet, R, Sigler, P.B.
Deposit date:1999-02-16
Release date:1999-02-23
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (3 Å)
Cite:A molecular mechanism for the phosphorylation-dependent regulation of heterotrimeric G proteins by phosducin.
Mol.Cell, 3, 1999
1TRO
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BU of 1tro by Molmil
CRYSTAL STRUCTURE OF TRP REPRESSOR OPERATOR COMPLEX AT ATOMIC RESOLUTION
Descriptor: DNA (5'-D(*TP*GP*TP*AP*CP*TP*AP*GP*TP*TP*AP*AP*CP*TP*AP*GP*T P*AP*C)-3'), PROTEIN (TRP REPRESSOR), TRYPTOPHAN
Authors:Otwinowski, Z, Schevitz, R.W, Zhang, R.-G, Lawson, C.L, Joachimiak, A, Marmorstein, R, Luisi, B.F, Sigler, P.B.
Deposit date:1992-08-30
Release date:1994-01-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of trp repressor/operator complex at atomic resolution.
Nature, 335, 1988
1YFG
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BU of 1yfg by Molmil
YEAST INITIATOR TRNA
Descriptor: YEAST INITIATOR TRNA
Authors:Basavappa, R, Sigler, P.B.
Deposit date:1997-05-08
Release date:1997-09-03
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (3 Å)
Cite:The 3 A crystal structure of yeast initiator tRNA: functional implications in initiator/elongator discrimination.
EMBO J., 10, 1991
1TBG
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BU of 1tbg by Molmil
BETA-GAMMA DIMER OF THE HETEROTRIMERIC G-PROTEIN TRANSDUCIN
Descriptor: TRANSDUCIN
Authors:Sondek, J.S, Bohm, A, Lambright, D.G, Hamm, H.E, Sigler, P.B.
Deposit date:1996-06-15
Release date:1997-04-01
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of a G-protein beta gamma dimer at 2.1A resolution.
Nature, 379, 1996
1B9X
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BU of 1b9x by Molmil
STRUCTURAL ANALYSIS OF PHOSDUCIN AND ITS PHOSPHORYLATION-REGULATED INTERACTION WITH TRANSDUCIN
Descriptor: GADOLINIUM ATOM, PROTEIN (PHOSDUCIN), PROTEIN (TRANSDUCIN)
Authors:Gaudet, R, Sigler, P.B.
Deposit date:1999-02-16
Release date:1999-02-23
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (3 Å)
Cite:A molecular mechanism for the phosphorylation-dependent regulation of heterotrimeric G proteins by phosducin.
Mol.Cell, 3, 1999
1AON
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BU of 1aon by Molmil
CRYSTAL STRUCTURE OF THE ASYMMETRIC CHAPERONIN COMPLEX GROEL/GROES/(ADP)7
Descriptor: ADENOSINE-5'-DIPHOSPHATE, GROEL, GROEL/GROES COMPLEX, ...
Authors:Xu, Z, Horwich, A.L, Sigler, P.B.
Deposit date:1997-07-08
Release date:1997-10-15
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (3 Å)
Cite:The crystal structure of the asymmetric GroEL-GroES-(ADP)7 chaperonin complex.
Nature, 388, 1997
1PP2
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BU of 1pp2 by Molmil
THE REFINED CRYSTAL STRUCTURE OF DIMERIC PHOSPHOLIPASE A2 AT 2.5 ANGSTROMS. ACCESS TO A SHIELDED CATALYTIC CENTER
Descriptor: CALCIUM-FREE PHOSPHOLIPASE A2
Authors:Brunie, S, Sigler, P.B.
Deposit date:1986-03-10
Release date:1986-05-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The refined crystal structure of dimeric phospholipase A2 at 2.5 A. Access to a shielded catalytic center.
J.Biol.Chem., 260, 1985

 

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