Author results

1IYO
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TOHO-1 BETA-LACTAMASE IN COMPLEX WITH CEFOTAXIME
Descriptor:Toho-1 beta-lactamase, SULFATE ION, CEFOTAXIME, ...
Authors:Shimamura, T., Ibuka, A., Fushinobu, S., Wakagi, T., Ishiguro, M., Ishii, Y., Matsuzawa, H.
Deposit date:2002-09-04
Release date:2002-12-11
Last modified:2017-03-15
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Acyl-intermediate Structures of the Extended-spectrum Class A beta -Lactamase, Toho-1, in Complex with Cefotaxime, Cephalothin, and Benzylpenicillin.
J.Biol.Chem., 277, 2002
1IYP
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TOHO-1 BETA-LACTAMASE IN COMPLEX WITH CEPHALOTHIN
Descriptor:Toho-1 beta-lactamase, SULFATE ION, CEPHALOTHIN GROUP
Authors:Shimamura, T., Ibuka, A., Fushinobu, S., Wakagi, T., Ishiguro, M., Ishii, Y., Matsuzawa, H.
Deposit date:2002-09-04
Release date:2002-12-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Acyl-intermediate Structures of the Extended-spectrum Class A beta -Lactamase, Toho-1, in Complex with Cefotaxime, Cephalothin, and Benzylpenicillin.
J.Biol.Chem., 277, 2002
1IYQ
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TOHO-1 BETA-LACTAMASE IN COMPLEX WITH BENZYLPENICILLIN
Descriptor:Toho-1 beta-lactamase, SULFATE ION, OPEN FORM - PENICILLIN G
Authors:Shimamura, T., Ibuka, A., Fushinobu, S., Wakagi, T., Ishiguro, M., Ishii, Y., Matsuzawa, H.
Deposit date:2002-09-04
Release date:2002-12-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Acyl-intermediate Structures of the Extended-spectrum Class A beta -Lactamase, Toho-1, in Complex with Cefotaxime, Cephalothin, and Benzylpenicillin.
J.Biol.Chem., 277, 2002
2ZQ7
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APO STRUCTURE OF CLASS A BETA-LACTAMASE TOHO-1 E166A/R274N/R276N TRIPLE MUTANT
Descriptor:Beta-lactamase Toho-1, SULFATE ION
Authors:Shimamura, T., Nitanai, Y., Uchiyama, T., Ago, H., Matsuzawa, H., Miyano, M.
Deposit date:2008-08-07
Release date:2009-07-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (0.94 Å)
Cite:Improvement of the Crystal Quality by the Surface Mutations on a Beta-Lactamase Toho-1
To be Published
2ZQ8
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APO STRUCTURE OF CLASS A BETA-LACTAMASE TOHO-1 R274N/R276N DOUBLE MUTANT
Descriptor:Beta-lactamase Toho-1, SULFATE ION
Authors:Shimamura, T., Nitanai, Y., Uchiyama, T., Ago, H., Matsuzawa, H., Miyano, M.
Deposit date:2008-08-07
Release date:2009-07-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.03 Å)
Cite:Improvement of crystal quality by surface mutations of beta-lactamase Toho-1
Acta Crystallogr.,Sect.F, 65, 2009
3RZE
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STRUCTURE OF THE HUMAN HISTAMINE H1 RECEPTOR IN COMPLEX WITH DOXEPIN
Descriptor:Histamine H1 receptor, Lysozyme chimera, (3E)-3-(dibenzo[b,e]oxepin-11(6H)-ylidene)-N,N-dimethylpropan-1-amine, ...
Authors:Shimamura, T., Han, G.W., Shiroishi, M., Weyand, S., Tsujimoto, H., Winter, G., Katritch, V., Abagyan, R., Cherezov, V., Liu, W., Kobayashi, T., Stevens, R., Iwata, S., GPCR Network (GPCR)
Deposit date:2011-05-11
Release date:2011-06-15
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structure of the human histamine H1 receptor complex with doxepin.
Nature, 475, 2011
2X79
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INWARD FACING CONFORMATION OF MHP1
Descriptor:HYDANTOIN TRANSPORT PROTEIN
Authors:Shimamura, T., Weyand, S., Beckstein, O., Rutherford, N.G., Hadden, J.M., Sharples, D., Sansom, M.S.P., Iwata, S., Henderson, P.J.F., Cameron, A.D.
Deposit date:2010-02-25
Release date:2010-05-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Molecular Basis of Alternating Access Membrane Transport by the Sodium-Hydantoin Transporter Mhp1.
Science, 328, 2010
4V4O
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CRYSTAL STRUCTURE OF THE CHAPERONIN COMPLEX CPN60/CPN10/(ADP)7 FROM THERMUS THERMOPHILUS
Descriptor:cpn60(GroEL), cpn10(GroES), MAGNESIUM ION, ...
Authors:Shimamura, T., Koike-Takeshita, A., Yokoyama, K., Masui, R., Murai, N., Yoshida, M., Taguchi, H., Iwata, S.
Deposit date:2004-05-23
Release date:2014-07-09
Last modified:2014-12-10
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of the native chaperonin complex from Thermus thermophilus revealed unexpected asymmetry at the cis-cavity
STRUCTURE, 12, 2004
2ZIY
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CRYSTAL STRUCTURE OF SQUID RHODOPSIN
Descriptor:Rhodopsin, RETINAL, PALMITIC ACID
Authors:Miyano, M., Shimamura, T.
Deposit date:2008-02-27
Release date:2008-05-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:Crystal structure of squid rhodopsin with intracellularly extended cytoplasmic region
J.Biol.Chem., 283, 2008
3VG9
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CRYSTAL STRUCTURE OF HUMAN ADENOSINE A2A RECEPTOR WITH AN ALLOSTERIC INVERSE-AGONIST ANTIBODY AT 2.7 A RESOLUTION
Descriptor:Adenosine receptor A2a, antibody fab fragment light chain, antibody fab fragment heavy chain, ...
Authors:Hino, T., Arakawa, T., Iwanari, H., Yurugi-Kobayashi, T., Ikeda-Suno, C., Nakada-Nakura, Y., Kusano-Arai, O., Weyand, S., Shimamura, T., Nomura, N., Cameron, A.D., Kobayashi, T., Hamakubo, T., Iwata, S., Murata, T.
Deposit date:2011-08-04
Release date:2012-02-01
Last modified:2012-02-15
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:G-protein-coupled receptor inactivation by an allosteric inverse-agonist antibody
Nature, 482, 2012
3VGA
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CRYSTAL STRUCTURE OF HUMAN ADENOSINE A2A RECEPTOR WITH AN ALLOSTERIC INVERSE-AGONIST ANTIBODY AT 3.1 A RESOLUTION
Descriptor:Adenosine receptor A2a, antibody fab fragment light chain, antibody fab fragment heavy chain, ...
Authors:Hino, T., Arakawa, T., Iwanari, H., Yurugi-Kobayashi, T., Ikeda-Suno, C., Nakada-Nakura, Y., Kusano-Arai, O., Weyand, S., Shimamura, T., Nomura, N., Cameron, A.D., Kobayashi, T., Hamakubo, T., Iwata, S., Murata, T.
Deposit date:2011-08-04
Release date:2012-02-01
Last modified:2012-02-15
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:G-protein-coupled receptor inactivation by an allosteric inverse-agonist antibody
Nature, 482, 2012
5WS3
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CRYSTAL STRUCTURES OF HUMAN OREXIN 2 RECEPTOR BOUND TO THE SELECTIVE ANTAGONIST EMPA DETERMINED BY SERIAL FEMTOSECOND CRYSTALLOGRAPHY AT SACLA
Descriptor:Orexin receptor type 2,GlgA glycogen synthase,Orexin receptor type 2, N-ethyl-2-[(6-methoxypyridin-3-yl)-(2-methylphenyl)sulfonyl-amino]-N-(pyridin-3-ylmethyl)ethanamide, OLEIC ACID, ...
Authors:Suno, R., Kimura, K., Nakane, T., Yamashita, K., Wang, J., Fujiwara, T., Yamanaka, Y., Im, D., Tsujimoto, H., Sasanuma, M., Horita, S., Hirokawa, T., Nango, E., Tono, K., Kameshima, T., Hatsui, T., Joti, Y., Yabashi, M., Shimamoto, K., Yamamoto, M., Rosenbaum, D.M., Iwata, S., Shimamura, T., Kobayashi, T.
Deposit date:2016-12-05
Release date:2017-12-13
Last modified:2018-06-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal Structures of Human Orexin 2 Receptor Bound to the Subtype-Selective Antagonist EMPA.
Structure, 26, 2018
4X8Y
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CRYSTAL STRUCTURE OF HUMAN PGRMC1 CYTOCHROME B5-LIKE DOMAIN
Descriptor:Membrane-associated progesterone receptor component 1, PROTOPORPHYRIN IX CONTAINING FE
Authors:Nakane, T., Yamamoto, T., Shimamura, T., Kobayashi, T., Kabe, Y., Suematsu, M.
Deposit date:2014-12-11
Release date:2016-03-23
Last modified:2016-03-30
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Haem-dependent dimerization of PGRMC1/Sigma-2 receptor facilitates cancer proliferation and chemoresistance
Nat Commun, 7, 2016
5WQC
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CRYSTAL STRUCTURE OF HUMAN OREXIN 2 RECEPTOR BOUND TO THE SELECTIVE ANTAGONIST EMPA DETERMINED BY THE SYNCHROTRON LIGHT SOURCE AT SPRING-8.
Descriptor:Orexin receptor type 2,GlgA glycogen synthase,Orexin receptor type 2, N-ethyl-2-[(6-methoxypyridin-3-yl)-(2-methylphenyl)sulfonyl-amino]-N-(pyridin-3-ylmethyl)ethanamide, OLEIC ACID, ...
Authors:Suno, R., Hirata, K., Yamashita, K., Tsujimoto, H., Sasanuma, M., Horita, S., Yamamoto, M., Rosenbaum, D.M., Iwata, S., Shimamura, T., Kobayashi, T.
Deposit date:2016-11-25
Release date:2017-11-29
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Crystal Structures of Human Orexin 2 Receptor Bound to the Subtype-Selective Antagonist EMPA
Structure, 26, 2018
2DCH
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CRYSTAL STRUCTURE OF ARCHAEAL INTRON-ENCODED HOMING ENDONUCLEASE I-TSP061I
Descriptor:putative homing endonuclease, CHLORIDE ION, SULFATE ION
Authors:Nakayama, H., Tsuge, H., Shimamura, T., Miyano, M., Nomura, N., Sako, Y.
Deposit date:2006-01-06
Release date:2006-07-06
Last modified:2011-11-16
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Structure of a hyperthermophilic archaeal homing endonuclease, I-Tsp061I: contribution of cross-domain polar networks to thermostability.
J.Mol.Biol., 365, 2007
4YBQ
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RAT GLUT5 WITH FV IN THE OUTWARD-OPEN FORM
Descriptor:Solute carrier family 2, facilitated glucose transporter member 5, antibody Fv fragment light chain, ...
Authors:Nomura, N., Shimamura, T., Iwata, S.
Deposit date:2015-02-19
Release date:2015-10-07
Last modified:2015-10-28
Method:X-RAY DIFFRACTION (3.27 Å)
Cite:Structure and mechanism of the mammalian fructose transporter GLUT5
Nature, 526, 2015
5XJM
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COMPLEX STRUCTURE OF ANGIOTENSIN II TYPE 2 RECEPTOR WITH FAB
Descriptor:Type-2 angiotensin II receptor,Soluble cytochrome b562,Type-2 angiotensin II receptor, FabH, FabL, ...
Authors:Asada, H., Horita, S., Shimamura, T., Iwata, S.
Deposit date:2017-05-02
Release date:2018-07-11
Last modified:2018-07-25
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Crystal structure of the human angiotensin II type 2 receptor bound to an angiotensin II analog
Nat. Struct. Mol. Biol., 25, 2018
2VPW
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POLYSULFIDE REDUCTASE WITH BOUND MENAQUINONE
Descriptor:THIOSULFATE REDUCTASE, NRFC PROTEIN, HYPOTHETICAL MEMBRANE SPANNING PROTEIN, ...
Authors:Jormakka, M., Yokoyama, K., Yano, T., Tamakoshi, M., Akimoto, S., Shimamura, T., Curmi, P., Iwata, S.
Deposit date:2008-03-09
Release date:2008-06-10
Last modified:2019-02-06
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Molecular Mechanism of Energy Conservation in Polysulfide Respiration.
Nat.Struct.Mol.Biol., 15, 2008
2VPX
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POLYSULFIDE REDUCTASE WITH BOUND QUINONE (UQ1)
Descriptor:THIOSULFATE REDUCTASE, NRFC PROTEIN, HYPOTHETICAL MEMBRANE SPANNING PROTEIN, ...
Authors:Jormakka, M., Yokoyama, K., Yano, T., Tamakoshi, M., Akimoto, S., Shimamura, T., Curmi, P., Iwata, S.
Deposit date:2008-03-09
Release date:2008-06-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Molecular Mechanism of Energy Conservation in Polysulfide Respiration.
Nat.Struct.Mol.Biol., 15, 2008
2VPY
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POLYSULFIDE REDUCTASE WITH BOUND QUINONE INHIBITOR, PENTACHLOROPHENOL (PCP)
Descriptor:THIOSULFATE REDUCTASE, NRFC PROTEIN, HYPOTHETICAL MEMBRANE SPANNING PROTEIN, ...
Authors:Jormakka, M., Yokoyama, K., Yano, T., Tamakoshi, M., Akimoto, S., Shimamura, T., Curmi, P., Iwata, S.
Deposit date:2008-03-09
Release date:2008-06-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Molecular Mechanism of Energy Conservation in Polysulfide Respiration.
Nat.Struct.Mol.Biol., 15, 2008
2VPZ
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POLYSULFIDE REDUCTASE NATIVE STRUCTURE
Descriptor:THIOSULFATE REDUCTASE, NRFC PROTEIN, HYPOTHETICAL MEMBRANE SPANNING PROTEIN, ...
Authors:Jormakka, M., Yokoyama, K., Yano, T., Tamakoshi, M., Akimoto, S., Shimamura, T., Curmi, P., Iwata, S.
Deposit date:2008-03-09
Release date:2008-06-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Molecular Mechanism of Energy Conservation in Polysulfide Respiration
Nat.Struct.Mol.Biol., 15, 2008
2ZQ9
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CEPHALOTHIN ACYL-INTERMEDIATE STRUCTURE OF CLASS A BETA-LACTAMASE TOHO-1 E166A/R274N/R276N TRIPLE MUTANT
Descriptor:Beta-lactamase Toho-1, SULFATE ION, 5-METHYLENE-2-[2-OXO-1-(2-THIOPHEN-2-YL-ACETYLAMINO)-ETHYL]-5,6-DIHYDRO-2H-[1,3]THIAZINE-4-CARBOXYLIC ACID, ...
Authors:Nitanai, Y., Shimamura, T., Uchiyama, T., Ishii, Y., Takehira, M., Yutani, K., Matsuzawa, H., Miyano, M.
Deposit date:2008-08-07
Release date:2009-07-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.07 Å)
Cite:Structural Basis of Extend Spectrum Beta-Lactamase in Correlation of Enzymatic Kinetics and Thermal Stability of Acyl-Intermediates
To be Published
2ZQA
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CEFOTAXIME ACYL-INTERMEDIATE STRUCTURE OF CLASS A BETA-LACTA TOHO-1 E166A/R274N/R276N TRIPLE MUTANT
Descriptor:Beta-lactamase Toho-1, CEFOTAXIME, C3' cleaved, ...
Authors:Nitanai, Y., Shimamura, T., Uchiyama, T., Ishii, Y., Takehira, M., Yutani, K., Matsuzawa, H., Miyano, M.
Deposit date:2008-08-07
Release date:2009-07-28
Last modified:2018-09-19
Method:X-RAY DIFFRACTION (0.95 Å)
Cite:Structural Basis of Extend Spectrum Beta-Lactamase in Correlation of Enzymatic Kinetics and Thermal Stability of Acyl-Intermediates
To be Published
2ZQC
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AZTREONAM ACYL-INTERMEDIATE STRUCTURE OF CLASS A BETA-LACTAM TOHO-1 E166A/R274N/R276N TRIPLE MUTANT
Descriptor:Beta-lactamase Toho-1, SULFATE ION, 2-({[(1Z)-1-(2-amino-1,3-thiazol-4-yl)-2-oxo-2-{[(2S,3S)-1-oxo-3-(sulfoamino)butan-2-yl]amino}ethylidene]amino}oxy)-2-methylpropanoic acid
Authors:Nitanai, Y., Shimamura, T., Uchiyama, T., Ishii, Y., Takehira, M., Yutani, K., Matsuzawa, H., Miyano, M.
Deposit date:2008-08-07
Release date:2009-07-28
Last modified:2011-08-31
Method:X-RAY DIFFRACTION (1.07 Å)
Cite:Structural Basis of Extend Spectrum Beta-Lactamase in Correlation of Enzymatic Kinetics and Thermal Stability of Acyl-Intermediates
To be Published
2ZQD
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CEFTAZIDIME ACYL-INTERMEDIATE STRUCTURE OF CLASS A BETA-LACT TOHO-1 E166A/R274N/R276N TRIPLE MUTANT
Descriptor:Beta-lactamase Toho-1, SULFATE ION, ACYLATED CEFTAZIDIME
Authors:Nitanai, Y., Shimamura, T., Uchiyama, T., Ishii, Y., Takehira, M., Yutani, K., Matsuzawa, H., Miyano, M.
Deposit date:2008-08-07
Release date:2009-07-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.19 Å)
Cite:Structural Basis of Extend Spectrum Beta-Lactamase in Correlation of Enzymatic Kinetics and Thermal Stability of Acyl-Intermediates
To be Published
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