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5GJR
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AN ATOMIC STRUCTURE OF THE HUMAN 26S PROTEASOME
Descriptor:26S protease regulatory subunit 4, 26S protease regulatory subunit 7, 26S protease regulatory subunit 10B, ...
Authors:Huang, X.L., Luan, B., Wu, J.P., Shi, Y.G.
Deposit date:2016-07-01
Release date:2016-09-07
Last modified:2017-04-05
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:An atomic structure of the human 26S proteasome.
Nat. Struct. Mol. Biol., 23, 2016
5GJQ
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STRUCTURE OF THE HUMAN 26S PROTEASOME BOUND TO USP14-UBAL
Descriptor:Proteasome subunit beta type-6, Proteasome subunit alpha type-6, Proteasome subunit beta type-7, ...
Authors:Huang, X.L., Luan, B., Wu, J.P., Shi, Y.G.
Deposit date:2016-07-01
Release date:2016-08-17
Last modified:2018-10-24
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:An atomic structure of the human 26S proteasome.
Nat. Struct. Mol. Biol., 23, 2016
3JCO
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STRUCTURE OF YEAST 26S PROTEASOME IN M1 STATE DERIVED FROM TITAN DATASET
Descriptor:Proteasome subunit beta type-6, Proteasome subunit beta type-7, Proteasome subunit beta type-1, ...
Authors:Luan, B., Huang, X.L., Wu, J.P., Shi, Y.G., Wang, F.
Deposit date:2016-01-06
Release date:2016-06-15
Last modified:2016-07-06
Method:ELECTRON MICROSCOPY (4.8 Å)
Cite:Structure of an endogenous yeast 26S proteasome reveals two major conformational states.
Proc.Natl.Acad.Sci.USA, 113, 2016
3JCP
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STRUCTURE OF YEAST 26S PROTEASOME IN M2 STATE DERIVED FROM TITAN DATASET
Descriptor:Proteasome subunit beta type-6, Proteasome subunit beta type-7, Proteasome subunit beta type-1, ...
Authors:Luan, B., Huang, X.L., Wu, J.P., Shi, Y.G., Wang, F.
Deposit date:2016-01-06
Release date:2016-06-15
Last modified:2016-07-06
Method:ELECTRON MICROSCOPY (4.6 Å)
Cite:Structure of an endogenous yeast 26S proteasome reveals two major conformational states.
Proc.Natl.Acad.Sci.USA, 113, 2016
5FCG
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CRYSTAL STRUCTURE OF BCL-2 IN COMPLEX WITH HBX-BH3 MOTIF
Descriptor:Apoptosis regulator Bcl-2, Protein X
Authors:Jiang, T.Y., Liu, M.H., Wu, J.P., Shi, Y.G.
Deposit date:2015-12-15
Release date:2016-02-10
Last modified:2016-02-24
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural and biochemical analysis of Bcl-2 interaction with the hepatitis B virus protein HBx
Proc.Natl.Acad.Sci.USA, 2016
5FN2
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CRYO-EM STRUCTURE OF GAMMA SECRETASE IN COMPLEX WITH A DRUG DAPT
Descriptor:NICASTRIN, PRESENILIN-1, GAMMA-SECRETASE SUBUNIT APH-1A, ...
Authors:Bai, X.C., Rajendra, E., Yang, G.H., Shi, Y.G., Scheres, S.H.W.
Deposit date:2015-11-10
Release date:2015-12-16
Last modified:2016-12-21
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Sampling the conformational space of the catalytic subunit of human gamma-secretase.
Elife, 4, 2015
5FN3
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CRYO-EM STRUCTURE OF GAMMA SECRETASE IN CLASS 1 OF THE APO- STATE ENSEMBLE
Descriptor:NICASTRIN, PRESENILIN-1, GAMMA-SECRETASE SUBUNIT APH-1A, ...
Authors:Bai, X.C., Rajendra, E., Yang, G.H., Shi, Y.G., Scheres, S.H.W.
Deposit date:2015-11-10
Release date:2015-12-16
Last modified:2016-12-21
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Sampling the conformational space of the catalytic subunit of human gamma-secretase.
Elife, 4, 2015
5FN4
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CRYO-EM STRUCTURE OF GAMMA SECRETASE IN CLASS 2 OF THE APO- STATE ENSEMBLE
Descriptor:NICASTRIN, PRESENILIN-1, GAMMA-SECRETASE SUBUNIT APH-1A, ...
Authors:Bai, X.C., Rajendra, E., Yang, G.H., Shi, Y.G., Scheres, S.H.W.
Deposit date:2015-11-10
Release date:2015-12-16
Last modified:2016-12-21
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Sampling the conformational space of the catalytic subunit of human gamma-secretase.
Elife, 4, 2015
5FN5
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CRYO-EM STRUCTURE OF GAMMA SECRETASE IN CLASS 3 OF THE APO- STATE ENSEMBLE
Descriptor:NICASTRIN, PRESENILIN-1, GAMMA-SECRETASE SUBUNIT APH-1A, ...
Authors:Bai, X.C., Rajendra, E., Yang, G.H., Shi, Y.G., Scheres, S.H.W.
Deposit date:2015-11-10
Release date:2015-12-16
Last modified:2016-12-21
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Sampling the conformational space of the catalytic subunit of human gamma-secretase.
Elife, 4, 2015
4NM6
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CRYSTAL STRUCTURE OF TET2-DNA COMPLEX
Descriptor:Methylcytosine dioxygenase TET2, 5'-D(*AP*CP*CP*AP*CP*(5CM)P*GP*GP*TP*GP*GP*T)-3', ZINC ION, ...
Authors:Hu, L., Li, Z., Cheng, J., Rao, Q., Gong, W., Liu, M., Wang, P., Xu, Y.
Deposit date:2013-11-14
Release date:2013-12-18
Last modified:2017-07-26
Method:X-RAY DIFFRACTION (2.026 Å)
Cite:Crystal Structure of TET2-DNA Complex: Insight into TET-Mediated 5mC Oxidation.
Cell(Cambridge,Mass.), 155, 2013
4M9S
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CRYSTAL STRUCTURE OF CED-4 BOUND CED-3 FRAGMENT
Descriptor:Cell death protein 4, CED-3 fragment, MAGNESIUM ION, ...
Authors:Huang, W.J., Jinag, T.Y., Choi, W.Y., Wang, J.W., Shi, Y.G.
Deposit date:2013-08-15
Release date:2013-10-23
Method:X-RAY DIFFRACTION (3.207 Å)
Cite:Mechanistic insights into CED-4-mediated activation of CED-3.
Genes Dev., 27, 2013
4M9X
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CRYSTAL STRUCTURE OF CED-4 BOUND CED-3 FRAGMENT
Descriptor:Cell death protein 4, CED-3 fragment, MAGNESIUM ION, ...
Authors:Huang, W.J., Jinag, T.Y., Choi, W.Y., Wang, J.W., Shi, Y.G.
Deposit date:2013-08-15
Release date:2013-10-23
Method:X-RAY DIFFRACTION (3.344 Å)
Cite:Mechanistic insights into CED-4-mediated activation of CED-3.
Genes Dev., 27, 2013
4M9Y
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CRYSTAL STRUCTURE OF CED-4 BOUND CED-3 FRAGMENT
Descriptor:Cell death protein 4, CED-3 fragment, MAGNESIUM ION, ...
Authors:Huang, W.J., Jinag, T.Y., Choi, W.Y., Wang, J.W., Shi, Y.G.
Deposit date:2013-08-15
Release date:2013-10-23
Method:X-RAY DIFFRACTION (4.2 Å)
Cite:Mechanistic insights into CED-4-mediated activation of CED-3.
Genes Dev., 27, 2013
4M9Z
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CRYSTAL STRUCTURE OF CED-4 BOUND CED-3 FRAGMENT
Descriptor:Cell death protein 4, CED-3 fragment, MAGNESIUM ION, ...
Authors:Huang, W.J., Jinag, T.Y., Choi, W.Y., Wang, J.W., Shi, Y.G.
Deposit date:2013-08-15
Release date:2013-10-23
Method:X-RAY DIFFRACTION (3.405 Å)
Cite:Mechanistic insights into CED-4-mediated activation of CED-3.
Genes Dev., 27, 2013
4M9R
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CRYSTAL STRUCTURE OF CED-3
Descriptor:Cell death protein 3
Authors:Xu, Y., Jeffrey, P.D., Shi, Y.G.
Deposit date:2013-08-15
Release date:2013-10-09
Method:X-RAY DIFFRACTION (2.656 Å)
Cite:Mechanistic insights into CED-4-mediated activation of CED-3
Genes Dev., 27, 2013
4HZU
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STRUCTURE OF A BACTERIAL ENERGY-COUPLING FACTOR TRANSPORTER
Descriptor:Energy-coupling factor transporter ATP-binding protein EcfA 1, Energy-coupling factor transporter ATP-binding protein EcfA 2, Energy-coupling factor transporter transmembrane protein EcfT, ...
Authors:Wang, T.L., Fu, G.B., Pan, X.J., Shi, Y.G.
Deposit date:2012-11-15
Release date:2013-04-17
Last modified:2013-05-22
Method:X-RAY DIFFRACTION (3.53 Å)
Cite:Structure of a bacterial energy-coupling factor transporter.
Nature, 497, 2013
4F6P
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CRYSTAL STRUCTURE OF THE YEAST METACASPASE YCA1 C276A MUTANT
Descriptor:Metacaspase-1, 1,1-diphenylethanol
Authors:Wong, A.H., Yan, C.Y., Shi, Y.G.
Deposit date:2012-05-15
Release date:2013-03-27
Method:X-RAY DIFFRACTION (1.619 Å)
Cite:Crystal structure of the metacaspase Yca1
To be Published
4GU0
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CRYSTAL STRUCTURE OF LSD2 WITH H3
Descriptor:Lysine-specific histone demethylase 1B, Histone H3.3, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Chen, F., Yang, H., Dong, Z., Fang, J., Zhu, T., Gong, W., Xu, Y.
Deposit date:2012-08-29
Release date:2013-02-13
Last modified:2013-07-10
Method:X-RAY DIFFRACTION (3.103 Å)
Cite:Structural insight into substrate recognition by histone demethylase LSD2/KDM1b
Cell Res., 23, 2013
4HSU
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CRYSTAL STRUCTURE OF LSD2-NPAC WITH H3(1-26)IN SPACE GROUP P21
Descriptor:Lysine-specific histone demethylase 1B, Putative oxidoreductase GLYR1, Histone H3, ...
Authors:Chen, F., Dong, Z., Fang, J., Xu, Y.
Deposit date:2012-10-30
Release date:2013-02-13
Last modified:2013-07-10
Method:X-RAY DIFFRACTION (1.988 Å)
Cite:Structural insight into substrate recognition by histone demethylase LSD2/KDM1b.
Cell Res., 23, 2013
4GU1
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CRYSTAL STRUCTURE OF LSD2
Descriptor:Lysine-specific histone demethylase 1B, FLAVIN-ADENINE DINUCLEOTIDE, CHLORIDE ION, ...
Authors:Chen, F., Dong, Z., Fang, J., Yang, Y., Li, Z., Xu, Y., Yang, H., Wang, P., Fang, R., Shi, Y., Xu, Y.
Deposit date:2012-08-29
Release date:2013-01-16
Last modified:2013-07-10
Method:X-RAY DIFFRACTION (2.939 Å)
Cite:LSD2/KDM1B and its cofactor NPAC/GLYR1 endow a structural and molecular model for regulation of H3K4 demethylation
Mol.Cell, 49, 2013
4GUR
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CRYSTAL STRUCTURE OF LSD2-NPAC WITH H3 IN SPACE GROUP P21
Descriptor:Lysine-specific histone demethylase 1B, Putative oxidoreductase GLYR1, Histone H3.3, ...
Authors:Chen, F., Dong, Z., Fang, J., Yang, Y., Li, Z., Xu, Y., Yang, H., Wang, P., Fang, R., Shi, Y., Xu, Y.
Deposit date:2012-08-29
Release date:2013-01-16
Last modified:2013-07-10
Method:X-RAY DIFFRACTION (2.506 Å)
Cite:LSD2/KDM1B and its cofactor NPAC/GLYR1 endow a structural and molecular model for regulation of H3K4 demethylation
Mol.Cell, 49, 2013
4GUS
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CRYSTAL STRUCTURE OF LSD2-NPAC WITH H3 IN SPACE GROUP P3221
Descriptor:Lysine-specific histone demethylase 1B, Putative oxidoreductase GLYR1, Histone H3.3, ...
Authors:Chen, F., Dong, Z., Fang, J., Yang, Y., Li, Z., Xu, Y., Yang, H., Wang, P., Fang, R., Shi, Y., Xu, Y.
Deposit date:2012-08-29
Release date:2013-01-16
Last modified:2013-07-10
Method:X-RAY DIFFRACTION (2.23 Å)
Cite:LSD2/KDM1B and its cofactor NPAC/GLYR1 endow a structural and molecular model for regulation of H3K4 demethylation
Mol.Cell, 49, 2013
4GUT
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CRYSTAL STRUCTURE OF LSD2-NPAC
Descriptor:Lysine-specific histone demethylase 1B, Putative oxidoreductase GLYR1, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Chen, F., Dong, Z., Fang, J., Yang, Y., Li, Z., Xu, Y., Yang, H., Wang, P., Fang, R., Shi, Y., Xu, Y.
Deposit date:2012-08-29
Release date:2013-01-16
Last modified:2013-07-10
Method:X-RAY DIFFRACTION (1.998 Å)
Cite:LSD2/KDM1B and its cofactor NPAC/GLYR1 endow a structural and molecular model for regulation of H3K4 demethylation
Mol.Cell, 49, 2013
4GUU
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CRYSTAL STRUCTURE OF LSD2-NPAC WITH TRANYLCYPROMINE
Descriptor:Lysine-specific histone demethylase 1B, Putative oxidoreductase GLYR1, [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl (2R,3S,4S)-5-[(3R,3aS,7aR)-10,11-dimethyl-1,4,6-trioxo-3-phenyl-2,3,5,6,7,7a-hexahydro-1H-benzo[g]pyrrolo[2,1-e]pteridin-8(4H)-yl]-2,3,4-trihydroxypentyl dihydrogen diphosphate, ...
Authors:Chen, F., Dong, Z., Fang, J., Yang, Y., Li, Z., Xu, Y., Yang, H., Wang, P., Xu, Y.
Deposit date:2012-08-29
Release date:2013-01-16
Last modified:2013-07-10
Method:X-RAY DIFFRACTION (2.302 Å)
Cite:LSD2/KDM1B and its cofactor NPAC/GLYR1 endow a structural and molecular model for regulation of H3K4 demethylation
Mol.Cell, 49, 2013
4HP1
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CRYSTAL STRUCTURE OF TET3 IN COMPLEX WITH A NON-CPG DSDNA
Descriptor:DNA (5'-D(*GP*CP*CP*AP*CP*(5CM)P*GP*GP*TP*GP*GP*C)-3'), LOC100036628 protein, ZINC ION
Authors:Chao, X., Tempel, W., Bian, C., Bountra, C., Arrowsmith, C.H., Edwards, A.M., Min, J., Structural Genomics Consortium (SGC)
Deposit date:2012-10-23
Release date:2012-12-05
Last modified:2012-12-19
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Tet3 CXXC Domain and Dioxygenase Activity Cooperatively Regulate Key Genes for Xenopus Eye and Neural Development.
Cell(Cambridge,Mass.), 151, 2012
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