Author results

3IKK
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CRYSTAL STRUCTURE ANALYSIS OF MSP DOMAIN
Descriptor:Vesicle-associated membrane protein-associated protein B/C
Authors:Shi, J., Lua, S., Song, J.
Deposit date:2009-08-06
Release date:2010-05-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Elimination of the native structure and solubility of the hVAPB MSP domain by the Pro56Ser mutation that causes amyotrophic lateral sclerosis.
Biochemistry, 49, 2010
5LUP
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STRUCTURES OF DHBN DOMAIN OF HUMAN BLM HELICASE
Descriptor:BLM protein, PHOSPHATE ION, POTASSIUM ION
Authors:Shi, J., Chen, W.-F., Zhang, B., Fan, S.-H., Ai, X., Liu, N.-N., Rety, S., Xi, X.-G.
Deposit date:2016-09-09
Release date:2017-03-01
Last modified:2017-04-19
Method:X-RAY DIFFRACTION (2.032 Å)
Cite:A helical bundle in the N-terminal domain of the BLM helicase mediates dimer and potentially hexamer formation.
J. Biol. Chem., 292, 2017
5LUS
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STRUCTURES OF DHBN DOMAIN OF PELECANUS CRISPUS BLM HELICASE
Descriptor:BLM helicase
Authors:Shi, J., Chen, W.-F., Zhang, B., Fan, S.-H., Ai, X., Liu, N.-N., Rety, S., Xi, X.-G.
Deposit date:2016-09-09
Release date:2017-03-01
Last modified:2017-04-19
Method:X-RAY DIFFRACTION (1.433 Å)
Cite:A helical bundle in the N-terminal domain of the BLM helicase mediates dimer and potentially hexamer formation.
J. Biol. Chem., 292, 2017
5LUT
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STRUCTURES OF DHBN DOMAIN OF GALLUS GALLUS BLM HELICASE
Descriptor:BLM helicase, PHOSPHATE ION
Authors:Shi, J., Chen, W.-F., Zhang, B., Fan, S.-H., Ai, X., Liu, N.-N., Rety, S., Xi, X.-G.
Deposit date:2016-09-09
Release date:2017-03-01
Last modified:2017-04-19
Method:X-RAY DIFFRACTION (2.72 Å)
Cite:A helical bundle in the N-terminal domain of the BLM helicase mediates dimer and potentially hexamer formation.
J. Biol. Chem., 292, 2017
5MK5
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STRUCTURES OF DHBN DOMAIN OF HUMAN BLM HELICASE
Descriptor:Bloom syndrome protein, IODIDE ION, POTASSIUM ION
Authors:Shi, J., Chen, W.-F., Zhang, B., Fan, S.-H., Ai, X., Liu, N.-N., Rety, S., Xi, X.-G.
Deposit date:2016-12-02
Release date:2017-03-01
Last modified:2017-04-19
Method:X-RAY DIFFRACTION (2.16 Å)
Cite:A helical bundle in the N-terminal domain of the BLM helicase mediates dimer and potentially hexamer formation.
J. Biol. Chem., 292, 2017
6J31
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CRYSTAL STRUCTURE ANALYSIS OF THE GLYCOTRANSFERASE OF KITACINNAMYCIN
Descriptor:kcn28, DBB-DSG-VAL-MEA-VAL-GLY-GLY-DVA-DLE, (2E,2'E)-3,3'-(1,2-phenylene)di(prop-2-enoic acid)
Authors:Shi, J., Liu, C.L., Zhang, B., Guo, W.J., Zhu, J.P., Xu, X., Xu, Q., Jiao, R.H., Tan, R.X., Ge, H.M.
Deposit date:2019-01-03
Release date:2020-01-15
Method:X-RAY DIFFRACTION (2.244 Å)
Cite:Genome mining and biosynthesis of kitacinnamycins as a STING activator.
Chem Sci, 10, 2019
6J32
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CRYSTAL STRUCTURE ANALYSIS OF THE GLYCOTRANSFERASE OF KITACINNAMYCIN
Descriptor:Kcn28
Authors:Shi, J., Liu, C.L., Zhang, B., Guo, W.J., Zhu, J.P., Xu, X., Xu, Q., Jiao, R.H., Tan, R.X., Ge, H.M.
Deposit date:2019-01-03
Release date:2020-01-15
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Genome mining and biosynthesis of kitacinnamycins as a STING activator.
Chem Sci, 10, 2019
5GNG
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CRYSTAL STRUCTURE OF BIOG FROM HAEMOPHILUS INFLUENZAE AT 1.26 ANGSTROMS RESOLUTION
Descriptor:Uncharacterized protein HI_1552
Authors:Shi, J., Guo, Z.
Deposit date:2016-07-20
Release date:2016-12-07
Last modified:2017-02-01
Method:X-RAY DIFFRACTION (1.26 Å)
Cite:An Atypical alpha / beta-Hydrolase Fold Revealed in the Crystal Structure of Pimeloyl-Acyl Carrier Protein Methyl Esterase BioG from Haemophilus influenzae
Biochemistry, 55, 2016
5H3B
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CRYSTAL STRUCTURE OF SEMET-BIOG FROM HAEMOPHILUS INFLUENZAE AT 1.49 ANGSTROMS RESOLUTION
Descriptor:Uncharacterized protein HI_1552, GLYCEROL, ISOPROPYL ALCOHOL
Authors:Shi, J., Guo, Z.
Deposit date:2016-10-21
Release date:2016-12-07
Last modified:2017-02-01
Method:X-RAY DIFFRACTION (1.492 Å)
Cite:An Atypical alpha / beta-Hydrolase Fold Revealed in the Crystal Structure of Pimeloyl-Acyl Carrier Protein Methyl Esterase BioG from Haemophilus influenzae
Biochemistry, 55, 2016
6K4Y
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CRYOEM STRUCTURE OF SIGMA APPROPRIATION COMPLEX
Descriptor:DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Shi, J., Wen, A., Feng, Y.
Deposit date:2019-05-27
Release date:2019-08-07
Last modified:2019-11-06
Method:ELECTRON MICROSCOPY (3.79 Å)
Cite:Structural basis of sigma appropriation.
Nucleic Acids Res., 47, 2019
6JNX
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CRYO-EM STRUCTURE OF A Q-ENGAGED ARRESTED COMPLEX
Descriptor:DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Feng, Y., Shi, J.
Deposit date:2019-03-18
Release date:2019-06-12
Last modified:2019-11-06
Method:ELECTRON MICROSCOPY (4.08 Å)
Cite:Structural basis of Q-dependent transcription antitermination.
Nat Commun, 10, 2019
6JNY
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CRYSTAL STRUCTURE OF BACTERIOPHAGE 21 Q PROTEIN
Descriptor:Antiterminator Q protein
Authors:Feng, Y., Shi, J.
Deposit date:2019-03-18
Release date:2019-06-12
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (1.451 Å)
Cite:Structural basis of Q-dependent transcription antitermination.
Nat Commun, 10, 2019
4GJT
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COMPLEX STRUCTURE OF NECTIN-4 BOUND TO MV-H
Descriptor:Hemagglutinin glycoprotein, Poliovirus receptor-related protein 4, N-ACETYL-D-GLUCOSAMINE
Authors:Zhang, X., Lu, G., Qi, J., Li, Y., He, Y., Xu, X., Shi, J., Zhang, C., Yan, J., Gao, G.F.
Deposit date:2012-08-10
Release date:2012-10-10
Last modified:2013-04-10
Method:X-RAY DIFFRACTION (3.1001 Å)
Cite:Structure of measles virus hemagglutinin bound to its epithelial receptor nectin-4
Nat.Struct.Mol.Biol., 20, 2013
6MS7
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PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA LIGAND BINDING DOMAIN IN COMPLEX WITH A NOVEL SELECTIVE PPAR-GAMMA MODULATOR VSP-77
Descriptor:Peroxisome proliferator-activated receptor gamma, PGC1 LXXLL motif, {[(1S)-1-(4-chlorophenyl)octyl]oxy}acetic acid
Authors:Yi, W., Jiang, H., Zhou, X.E., Shi, J., Zhao, G., Zhang, X., Sun, Y., Suino-Powell, K., Li, J., Li, J., Melcher, K., Xu, H.E.
Deposit date:2018-10-16
Release date:2019-10-23
Last modified:2020-01-08
Method:X-RAY DIFFRACTION (1.43 Å)
Cite:Identification and Structural Insight of a Safe and Effective PPAR-gamma Modulator for Anti-Diabetic Drug Discovery
To Be Published
2WN9
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CRYSTAL STRUCTURE OF APLYSIA ACHBP IN COMPLEX WITH 4-0H-DMXBA
Descriptor:SOLUBLE ACETYLCHOLINE RECEPTOR, 4-[(E)-5,6-DIHYDRO-2,3'-BIPYRIDIN-3(4H)-YLIDENEMETHYL]-3-METHOXYPHENOL, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Sulzenbacher, G., Hibbs, R., Shi, J., Talley, T., Conrod, S., Kem, W., Taylor, P., Marchot, P., Bourne, Y.
Deposit date:2009-07-07
Release date:2009-09-01
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural determinants for interaction of partial agonists with acetylcholine binding protein and neuronal alpha7 nicotinic acetylcholine receptor.
Embo J., 28, 2009
2WNC
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CRYSTAL STRUCTURE OF APLYSIA ACHBP IN COMPLEX WITH TROPISETRON
Descriptor:Soluble acetylcholine receptor, (3-ENDO)-8-METHYL-8-AZABICYCLO[3.2.1]OCT-3-YL 1H-INDOLE-3-CARBOXYLATE
Authors:Sulzenbacher, G., Hibbs, R., Shi, J., Talley, T., Conrod, S., Kem, W., Taylor, P., Marchot, P., Bourne, Y.
Deposit date:2009-07-08
Release date:2009-09-01
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural determinants for interaction of partial agonists with acetylcholine binding protein and neuronal alpha7 nicotinic acetylcholine receptor.
EMBO J., 28, 2009
2WNJ
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CRYSTAL STRUCTURE OF APLYSIA ACHBP IN COMPLEX WITH DMXBA
Descriptor:SOLUBLE ACETYLCHOLINE RECEPTOR, (3E)-3-[(2,4-DIMETHOXYPHENYL)METHYLIDENE]-3,4,5,6-TETRAHYDRO-2,3'-BIPYRIDINE, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Sulzenbacher, G., Hibbs, R., Shi, J., Talley, T., Conrod, S., Kem, W., Taylor, P., Marchot, P., Bourne, Y.
Deposit date:2009-07-09
Release date:2009-09-01
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural Determinants for Interaction of Partial Agonists with Acetylcholine Binding Protein and Neuronal Alpha7 Nicotinic Acetylcholine Receptor.
Embo J., 28, 2009
2WNL
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CRYSTAL STRUCTURE OF APLYSIA ACHBP IN COMPLEX WITH ANABASEINE
Descriptor:SOLUBLE ACETYLCHOLINE RECEPTOR, 3,4,5,6-tetrahydro-2,3'-bipyridine, 5-amino-1-pyridin-3-ylpentan-1-one, ...
Authors:Sulzenbacher, G., Hibbs, R., Shi, J., Talley, T., Conrod, S., Kem, W., Taylor, P., Marchot, P., Bourne, Y.
Deposit date:2009-07-09
Release date:2009-09-01
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural determinants for interaction of partial agonists with acetylcholine binding protein and neuronal alpha7 nicotinic acetylcholine receptor.
EMBO J., 28, 2009
5CB2
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THE STRUCTURE OF CANDIDA ALBICANS SEY1P IN COMPLEX WITH GMPPNP
Descriptor:Protein SEY1, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER
Authors:Yan, L., Sun, S., Wang, W., Shi, J., Hu, X., Wang, S., Rao, Z., Hu, J., Lou, Z.
Deposit date:2015-06-30
Release date:2015-09-23
Last modified:2015-10-07
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structures of the yeast dynamin-like GTPase Sey1p provide insight into homotypic ER fusion
J.Cell Biol., 210, 2015
5HDE
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CRYSTAL STRUCTURE OF PTPN12 CATALYTIC DOMAIN
Descriptor:Tyrosine-protein phosphatase non-receptor type 12, PHOSPHATE ION
Authors:Dong, H., Li, S., Shi, J.
Deposit date:2016-01-05
Release date:2017-01-18
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:Crystal Structure of PTPN12 Catalytic Domain
To Be Published
6LK0
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CRYSTAL STRUCTURE OF HUMAN WILD TYPE TRIP13
Descriptor:Pachytene checkpoint protein 2 homolog
Authors:Wang, Y., Huang, J., Li, B., Xue, H., Tricot, G., Hu, L., Xu, Z., Sun, X., Chang, S., Gao, L., Tao, Y., Xu, H., Xie, Y., Xiao, W., Yu, D., Kong, Y., Chen, G., Sun, X., Lian, F., Zhang, N., Wu, X., Mao, Z., Zhan, F., Zhu, W., Shi, J.
Deposit date:2019-12-17
Release date:2020-01-22
Last modified:2020-02-12
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:A Small-Molecule Inhibitor Targeting TRIP13 Suppresses Multiple Myeloma Progression.
Cancer Res., 80, 2020
6LNT
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CRYO-EM STRUCTURE OF IMMATURE ZIKA VIRUS IN COMPLEX WITH HUMAN ANTIBODY DV62.5 FAB
Descriptor:Envelope protein, pre-membrane protein, Fab DV62.5 heavy-chain variable region, ...
Authors:Tan, T.Y., Fibriansah, G., Kostyuchenko, V.A., Ng, T.S., Lim, X.X., Lim, X.N., Shi, J., Morais, M.C., Corti, D., Lok, S.M.
Deposit date:2020-01-02
Release date:2020-02-26
Method:ELECTRON MICROSCOPY (8 Å)
Cite:Capsid protein structure in Zika virus reveals the flavivirus assembly process.
Nat Commun, 11, 2020
6LNU
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CRYO-EM STRUCTURE OF IMMATURE ZIKA VIRUS
Descriptor:Genome polyprotein
Authors:Tan, T.Y., Fibriansah, G., Kostyuchenko, V.A., Ng, T.S., Lim, X.X., Lim, X.N., Shi, J., Morais, M.C., Corti, D., Lok, S.M.
Deposit date:2020-01-02
Release date:2020-02-26
Method:ELECTRON MICROSCOPY (9 Å)
Cite:Capsid protein structure in Zika virus reveals the flavivirus assembly process.
Nat Commun, 11, 2020
1J4E
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FRUCTOSE-1,6-BISPHOSPHATE ALDOLASE COVALENTLY BOUND TO THE SUBSTRATE DIHYDROXYACETONE PHOSPHATE
Descriptor:FRUCTOSE-BISPHOSPHATE ALDOLASE A, 1,3-DIHYDROXYACETONEPHOSPHATE
Authors:Choi, K.H., Shi, J., Hopkins, C.E., Tolan, D.R., Allen, K.N.
Deposit date:2001-09-19
Release date:2002-02-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Snapshots of catalysis: the structure of fructose-1,6-(bis)phosphate aldolase covalently bound to the substrate dihydroxyacetone phosphate.
Biochemistry, 40, 2001
1JZW
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ARSENATE REDUCTASE + SODIUM ARSENATE FROM E. COLI
Descriptor:ARSENATE REDUCTASE, SULFATE ION, SULFITE ION, ...
Authors:Martin, P., DeMel, S., Shi, J., Gladysheva, T., Gatti, D.L., Rosen, B.P., Edwards, B.F.
Deposit date:2001-09-17
Release date:2001-11-28
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Insights into the structure, solvation, and mechanism of ArsC arsenate reductase, a novel arsenic detoxification enzyme.
Structure, 9, 2001