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3WY1
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CRYSTAL STRUCTURE OF ALPHA-GLUCOSIDASE
Descriptor:Alpha-glucosidase, MAGNESIUM ION, GLYCEROL, ...
Authors:Shen, X., Gai, Z., Kato, K., Yao, M.
Deposit date:2014-08-18
Release date:2015-06-10
Last modified:2018-03-21
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structural analysis of the alpha-glucosidase HaG provides new insights into substrate specificity and catalytic mechanism
Acta Crystallogr. D Biol. Crystallogr., 71, 2015
3WY2
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CRYSTAL STRUCTURE OF ALPHA-GLUCOSIDASE IN COMPLEX WITH GLUCOSE
Descriptor:Alpha-glucosidase, MAGNESIUM ION, GLYCEROL, ...
Authors:Shen, X., Gai, Z., Kato, K., Yao, M.
Deposit date:2014-08-18
Release date:2015-06-10
Last modified:2018-03-21
Method:X-RAY DIFFRACTION (1.471 Å)
Cite:Structural analysis of the alpha-glucosidase HaG provides new insights into substrate specificity and catalytic mechanism
Acta Crystallogr. D Biol. Crystallogr., 71, 2015
3WY3
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CRYSTAL STRUCTURE OF ALPHA-GLUCOSIDASE MUTANT D202N IN COMPLEX WITH GLUCOSE AND GLYCEROL
Descriptor:Alpha-glucosidase, MAGNESIUM ION, GLYCEROL, ...
Authors:Shen, X., Gai, Z., Kato, K., Yao, M.
Deposit date:2014-08-18
Release date:2015-06-10
Last modified:2018-03-21
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural analysis of the alpha-glucosidase HaG provides new insights into substrate specificity and catalytic mechanism
Acta Crystallogr. D Biol. Crystallogr., 71, 2015
3WY4
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CRYSTAL STRUCTURE OF ALPHA-GLUCOSIDASE MUTANT E271Q IN COMPLEX WITH MALTOSE
Descriptor:Alpha-glucosidase, MAGNESIUM ION, GLYCEROL, ...
Authors:Shen, X., Gai, Z., Kato, K., Yao, M.
Deposit date:2014-08-18
Release date:2015-06-10
Last modified:2018-03-21
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural analysis of the alpha-glucosidase HaG provides new insights into substrate specificity and catalytic mechanism
Acta Crystallogr. D Biol. Crystallogr., 71, 2015
3PCU
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CRYSTAL STRUCTURE OF HUMAN RETINOIC X RECEPTOR ALPHA LIGAND-BINDING DOMAIN COMPLEXED WITH LX0278 AND SRC1 PEPTIDE
Descriptor:Retinoic acid receptor RXR-alpha, Nuclear receptor coactivator 2, 2-[(2S)-6-(2-methylbut-3-en-2-yl)-7-oxo-2,3-dihydro-7H-furo[3,2-g]chromen-2-yl]propan-2-yl acetate
Authors:Zhang, H., Zhang, Y., Shen, H., Chen, J., Li, C., Chen, L., Hu, L., Jiang, H., Shen, X.
Deposit date:2010-10-22
Release date:2011-11-16
Last modified:2012-04-11
Method:X-RAY DIFFRACTION (2 Å)
Cite:(+)-Rutamarin as a Dual Inducer of Both GLUT4 Translocation and Expression Efficiently Ameliorates Glucose Homeostasis in Insulin-Resistant Mice.
Plos One, 7, 2012
3VBF
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CRYSTAL STRUCTURE OF FORMALDEHYDE TREATED HUMAN ENTEROVIRUS 71 (SPACE GROUP I23)
Descriptor:Genome Polyprotein, capsid protein VP1, capsid protein VP2, ...
Authors:Wang, X., Peng, W., Ren, J., Hu, Z., Xu, J., Lou, Z., Li, X., Yin, W., Shen, X., Porta, C., Walter, T.S., Evans, G., Axford, D., Owen, R., Rowlands, D.J., Wang, J., Stuart, D.I., Fry, E.E., Rao, Z.
Deposit date:2012-01-02
Release date:2012-02-29
Last modified:2012-04-25
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:A sensor-adaptor mechanism for enterovirus uncoating from structures of EV71.
Nat.Struct.Mol.Biol., 19, 2012
3VBH
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CRYSTAL STRUCTURE OF FORMALDEHYDE TREATED HUMAN ENTEROVIRUS 71 (SPACE GROUP R32)
Descriptor:Genome Polyprotein, capsid protein VP1, Genome polyprotein, ...
Authors:Wang, X., Peng, W., Ren, J., Hu, Z., Xu, J., Lou, Z., Li, X., Yin, W., Shen, X., Porta, C., Walter, T.S., Evans, G., Axford, D., Owen, R., Rowlands, D.J., Wang, J., Stuart, D.I., Fry, E.E., Rao, Z.
Deposit date:2012-01-02
Release date:2012-02-29
Last modified:2012-05-02
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:A sensor-adaptor mechanism for enterovirus uncoating from structures of EV71.
Nat.Struct.Mol.Biol., 19, 2012
3VBO
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CRYSTAL STRUCTURE OF FORMALDEHYDE TREATED EMPTY HUMAN ENTEROVIRUS 71 PARTICLE (CRYO AT 100K)
Descriptor:Genome Polyprotein, capsid protein VP1, capsid protein VP2, ...
Authors:Wang, X., Peng, W., Ren, J., Hu, Z., Xu, J., Lou, Z., Li, X., Yin, W., Shen, X., Porta, C., Walter, T.S., Evans, G., Axford, D., Owen, R., Rowlands, D.J., Wang, J., Stuart, D.I., Fry, E.E., Rao, Z.
Deposit date:2012-01-02
Release date:2012-02-29
Last modified:2012-05-02
Method:X-RAY DIFFRACTION (2.88 Å)
Cite:A sensor-adaptor mechanism for enterovirus uncoating from structures of EV71.
Nat.Struct.Mol.Biol., 19, 2012
3VBR
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CRYSTAL STRUCTURE OF FORMALDEHYDE TREATED EMPTY HUMAN ENTEROVIRUS 71 PARTICLE (ROOM TEMPERATURE)
Descriptor:Genome Polyprotein, capsid protein VP1, capsid protein VP0, ...
Authors:Wang, X., Peng, W., Ren, J., Hu, Z., Xu, J., Lou, Z., Li, X., Yin, W., Shen, X., Porta, C., Walter, T.S., Evans, G., Axford, D., Owen, R., Rowlands, D.J., Wang, J., Stuart, D.I., Fry, E.E., Rao, Z.
Deposit date:2012-01-02
Release date:2012-02-29
Last modified:2012-05-09
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:A sensor-adaptor mechanism for enterovirus uncoating from structures of EV71.
Nat.Struct.Mol.Biol., 19, 2012
3VBS
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CRYSTAL STRUCTURE OF HUMAN ENTEROVIRUS 71
Descriptor:Genome Polyprotein, capsid protein VP1, capsid protein VP2, ...
Authors:Wang, X., Peng, W., Ren, J., Hu, Z., Xu, J., Lou, Z., Li, X., Yin, W., Shen, X., Porta, C., Walter, T.S., Evans, G., Axford, D., Owen, R., Rowlands, D.J., Wang, J., Stuart, D.I., Fry, E.E., Rao, Z.
Deposit date:2012-01-02
Release date:2012-02-29
Last modified:2012-05-02
Method:X-RAY DIFFRACTION (3 Å)
Cite:A sensor-adaptor mechanism for enterovirus uncoating from structures of EV71.
Nat.Struct.Mol.Biol., 19, 2012
3VBU
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CRYSTAL STRUCTURE OF EMPTY HUMAN ENTEROVIRUS 71 PARTICLE
Descriptor:Genome Polyprotein, capsid protein VP1, capsid protein VP0, ...
Authors:Wang, X., Peng, W., Ren, J., Hu, Z., Xu, J., Lou, Z., Li, X., Yin, W., Shen, X., Porta, C., Walter, T.S., Evans, G., Axford, D., Owen, R., Rowlands, D.J., Wang, J., Stuart, D.I., Fry, E.E., Rao, Z.
Deposit date:2012-01-02
Release date:2012-02-29
Last modified:2012-05-02
Method:X-RAY DIFFRACTION (4 Å)
Cite:A sensor-adaptor mechanism for enterovirus uncoating from structures of EV71.
Nat.Struct.Mol.Biol., 19, 2012
5C4W
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CRYSTAL STRUCTURE OF COXSACKIEVIRUS A16
Descriptor:VP1, VP2, VP3, ...
Authors:Ren, J., Wang, X., Zhu, L., Hu, Z., Gao, Q., Yang, P., Li, X., Wang, J., Shen, X., Fry, E.E., Rao, Z., Stuart, D.I.
Deposit date:2015-06-18
Release date:2015-08-26
Last modified:2015-09-30
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structures of Coxsackievirus A16 Capsids with Native Antigenicity: Implications for Particle Expansion, Receptor Binding, and Immunogenicity.
J.Virol., 89, 2015
5C8C
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CRYSTAL STRUCTURE OF RECOMBINANT COXSACKIEVIRUS A16 CAPSID
Descriptor:VP1, VP0, VP3, ...
Authors:Ren, J., Wang, X., Zhu, L., Hu, Z., Gao, Q., Yang, P., Li, X., Wang, J., Shen, X., Fry, E.E., Rao, Z., Stuart, D.I.
Deposit date:2015-06-25
Release date:2015-09-30
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structures of Coxsackievirus A16 Capsids with Native Antigenicity: Implications for Particle Expansion, Receptor Binding, and Immunogenicity.
J.Virol., 89, 2015
5C9A
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CRYSTAL STRUCTURE OF EMPTY COXSACKIEVIRUS A16 PARTICLE
Descriptor:VP1, VP0, VP3, ...
Authors:Ren, J., Wang, X., Zhu, L., Hu, Z., Gao, Q., Yang, P., Li, X., Wang, J., Shen, X., Fry, E.E., Rao, Z., Stuart, D.I.
Deposit date:2015-06-26
Release date:2015-08-26
Last modified:2015-09-30
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structures of Coxsackievirus A16 Capsids with Native Antigenicity: Implications for Particle Expansion, Receptor Binding, and Immunogenicity.
J.Virol., 89, 2015
3DOY
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CRYSTAL STRUCTURE OF (3R)-HYDROXYACYL-ACYL CARRIER PROTEIN DEHYDRATASE (FABZ) FROM HELICOBACTER PYLORI IN COMPLEX WITH COMPOUND 3I
Descriptor:(3R)-hydroxymyristoyl-acyl carrier protein dehydratase, CHLORIDE ION, BENZAMIDINE, ...
Authors:Zhang, L., He, L., Liu, X., Liu, H., Shen, X., Jiang, H.
Deposit date:2008-07-07
Release date:2009-05-05
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Discovering potent inhibitors against the beta-hydroxyacyl-acyl carrier protein dehydratase (FabZ) of Helicobacter pylori: structure-based design, synthesis, bioassay, and crystal structure determination.
J.Med.Chem., 52, 2009
3DOZ
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CRYSTAL STRUCTURE OF (3R)-HYDROXYACYL-ACYL CARRIER PROTEIN DEHYDRATASE (FABZ) FROM HELICOBACTER PYLORI IN COMPLEX WITH COMPOUND 3K
Descriptor:(3R)-hydroxymyristoyl-acyl carrier protein dehydratase, CHLORIDE ION, BENZAMIDINE, ...
Authors:Zhang, L., He, L., Liu, X., Liu, H., Shen, X., Jiang, H.
Deposit date:2008-07-07
Release date:2009-05-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Discovering potent inhibitors against the beta-hydroxyacyl-acyl carrier protein dehydratase (FabZ) of Helicobacter pylori: structure-based design, synthesis, bioassay, and crystal structure determination.
J.Med.Chem., 52, 2009
3DP0
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CRYSTAL STRUCTURE OF (3R)-HYDROXYACYL-ACYL CARRIER PROTEIN DEHYDRATASE (FABZ) FROM HELICOBACTER PYLORI IN COMPLEX WITH COMPOUND 3M
Descriptor:(3R)-hydroxymyristoyl-acyl carrier protein dehydratase, CHLORIDE ION, BENZAMIDINE, ...
Authors:Zhang, L., He, L., Liu, X., Liu, H., Shen, X., Jiang, H.
Deposit date:2008-07-07
Release date:2009-05-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Discovering potent inhibitors against the beta-hydroxyacyl-acyl carrier protein dehydratase (FabZ) of Helicobacter pylori: structure-based design, synthesis, bioassay, and crystal structure determination.
J.Med.Chem., 52, 2009
3DP1
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CRYSTAL STRUCTURE OF (3R)-HYDROXYACYL-ACYL CARRIER PROTEIN DEHYDRATASE (FABZ) FROM HELICOBACTER PYLORI IN COMPLEX WITH COMPOUND 3N
Descriptor:(3R)-hydroxymyristoyl-acyl carrier protein dehydratase, CHLORIDE ION, BENZAMIDINE, ...
Authors:Zhang, L., He, L., Liu, X., Liu, H., Shen, X., Jiang, H.
Deposit date:2008-07-07
Release date:2009-05-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Discovering potent inhibitors against the beta-hydroxyacyl-acyl carrier protein dehydratase (FabZ) of Helicobacter pylori: structure-based design, synthesis, bioassay, and crystal structure determination.
J.Med.Chem., 52, 2009
3DP2
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CRYSTAL STRUCTURE OF (3R)-HYDROXYACYL-ACYL CARRIER PROTEIN DEHYDRATASE (FABZ) FROM HELICOBACTER PYLORI IN COMPLEX WITH COMPOUND 3J
Descriptor:(3R)-hydroxymyristoyl-acyl carrier protein dehydratase, CHLORIDE ION, BENZAMIDINE, ...
Authors:Zhang, L., He, L., Liu, X., Liu, H., Shen, X., Jiang, H.
Deposit date:2008-07-07
Release date:2009-05-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Discovering potent inhibitors against the beta-hydroxyacyl-acyl carrier protein dehydratase (FabZ) of Helicobacter pylori: structure-based design, synthesis, bioassay, and crystal structure determination.
J.Med.Chem., 52, 2009
3DP3
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CRYSTAL STRUCTURE OF (3R)-HYDROXYACYL-ACYL CARRIER PROTEIN DEHYDRATASE (FABZ) FROM HELICOBACTER PYLORI IN COMPLEX WITH COMPOUND 3Q
Descriptor:(3R)-hydroxymyristoyl-acyl carrier protein dehydratase, CHLORIDE ION, BENZAMIDINE, ...
Authors:Zhang, L., He, L., Liu, X., Liu, H., Shen, X., Jiang, H.
Deposit date:2008-07-07
Release date:2009-05-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Discovering potent inhibitors against the beta-hydroxyacyl-acyl carrier protein dehydratase (FabZ) of Helicobacter pylori: structure-based design, synthesis, bioassay, and crystal structure determination.
J.Med.Chem., 52, 2009
4OIV
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STRUCTURAL BASIS FOR SMALL MOLECULE NDB AS A SELECTIVE ANTAGONIST OF FXR
Descriptor:Bile acid receptor, N-benzyl-N-(3-tert-butyl-4-hydroxyphenyl)-2,6-dichloro-4-(dimethylamino)benzamide
Authors:Xu, X., Chen, L., Hu, L., Shen, X.
Deposit date:2014-01-20
Release date:2015-03-25
Last modified:2015-08-19
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural Basis for Small Molecule NDB (N-Benzyl-N-(3-(tert-butyl)-4-hydroxyphenyl)-2,6-dichloro-4-(dimethylamino) Benzamide) as a Selective Antagonist of Farnesoid X Receptor alpha (FXR alpha ) in Stabilizing the Homodimerization of the Receptor.
J.Biol.Chem., 290, 2015
3R5M
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CRYSTAL STRUCTURE OF RXRALPHALBD COMPLEXED WITH THE AGONIST MAGNOLOL
Descriptor:Retinoic acid receptor RXR-alpha, Nuclear receptor coactivator 2, 5,5'-di(prop-2-en-1-yl)biphenyl-2,2'-diol
Authors:Zhang, H., Chen, L., Chen, J., Hu, L., Jiang, H., Shen, X.
Deposit date:2011-03-18
Release date:2012-02-08
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Molecular determinants of magnolol targeting both RXR(alpha) and PPAR(gamma).
Plos One, 6, 2011
3R5N
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CRYSTAL STRUCTURE OF PPARGAMMALBD COMPLEXED WITH THE AGONIST MAGNOLOL
Descriptor:Peroxisome proliferator-activated receptor gamma, 5,5'-di(prop-2-en-1-yl)biphenyl-2,2'-diol
Authors:Zhang, H., Chen, L., Chen, J., Hu, L., Jiang, H., Shen, X.
Deposit date:2011-03-18
Release date:2012-02-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:Molecular determinants of magnolol targeting both RXR(alpha) and PPAR(gamma).
Plos One, 6, 2011
1IPB
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CRYSTAL STRUCTURE OF EUKARYOTIC INITIATION FACTOR 4E COMPLEXED WITH 7-METHYL GPPPA
Descriptor:EUKARYOTIC TRANSLATION INITIATION FACTOR 4E, P1-7-METHYLGUANOSINE-P3-ADENOSINE-5',5'-TRIPHOSPHATE
Authors:Tomoo, K., Shen, X., Okabe, K., Nozoe, Y., Fukuhara, S., Morino, S., Ishida, T., Taniguchi, T., Hasegawa, H., Terashima, A., Sasaki, M., Katsuya, Y., Kitamura, K., Miyoshi, H., Ishikawa, M., Miura, K.
Deposit date:2001-05-08
Release date:2002-05-08
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structures of 7-methylguanosine 5'-triphosphate (m(7)GTP)- and P(1)-7-methylguanosine-P(3)-adenosine-5',5'-triphosphate (m(7)GpppA)-bound human full-length eukaryotic initiation factor 4E: biological importance of the C-terminal flexible region
BIOCHEM.J., 362, 2002
1IPC
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CRYSTAL STRUCTURE OF EUKARYOTIC INITIATION FACTOR 4E COMPLEXED WITH 7-METHYL GTP
Descriptor:EUKARYOTIC TRANSLATION INITIATION FACTOR 4E, 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE
Authors:Tomoo, K., Shen, X., Okabe, K., Nozoe, Y., Fukuhara, S., Morino, S., Ishida, T., Taniguchi, T., Hasegawa, H., Terashima, A., Sasaki, M., Katsuya, Y., Kitamura, K., Miyoshi, H., Ishikawa, M., Miura, K.
Deposit date:2001-05-08
Release date:2002-05-08
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structures of 7-methylguanosine 5'-triphosphate (m(7)GTP)- and P(1)-7-methylguanosine-P(3)-adenosine-5',5'-triphosphate (m(7)GpppA)-bound human full-length eukaryotic initiation factor 4E: biological importance of the C-terminal flexible region
BIOCHEM.J., 362, 2002