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1C28
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BU of 1c28 by Molmil
THE CRYSTAL STRUCTURE OF A COMPLMENT-1Q FAMILY PROTEIN SUGGESTS AN EVOLUTIONARY LINK TO TUMOR NECROSIS FACTOR
Descriptor: PROTEIN (30 KD ADIPOCYTE COMPLEMENT-RELATED PROTEIN PRECURSOR (ACRP30))
Authors:Shapiro, L, Scherer, P.
Deposit date:1999-07-22
Release date:1999-08-04
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The crystal structure of a complement-1q family protein suggests an evolutionary link to tumor necrosis factor.
Curr.Biol., 8, 1998
1NEU
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BU of 1neu by Molmil
STRUCTURE OF MYELIN MEMBRANE ADHESION MOLECULE P0
Descriptor: MYELIN P0 PROTEIN
Authors:Shapiro, L, Doyle, J.P, Hensley, P, Colman, D.R, Hendrickson, W.A.
Deposit date:1996-09-24
Release date:1997-05-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of the extracellular domain from P0, the major structural protein of peripheral nerve myelin.
Neuron, 17, 1996
1NCH
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BU of 1nch by Molmil
STRUCTURAL BASIS OF CELL-CELL ADHESION BY CADHERINS
Descriptor: N-CADHERIN, YTTERBIUM (III) ION
Authors:Shapiro, L, Fannon, A.M, Kwong, P.D, Thompson, A, Lehmann, M.S, Grubel, G, Legrand, J.-F, Als-Nielsen, J, Colman, D.R, Hendrickson, W.A.
Deposit date:1995-03-23
Release date:1995-07-10
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis of cell-cell adhesion by cadherins.
Nature, 374, 1995
1NCG
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BU of 1ncg by Molmil
STRUCTURAL BASIS OF CELL-CELL ADHESION BY CADHERINS
Descriptor: N-CADHERIN, YTTERBIUM (III) ION
Authors:Shapiro, L, Fannon, A.M, Kwong, P.D, Thompson, A, Lehmann, M.S, Grubel, G, Legrand, J.-F, Als-Nielsen, J, Colman, D.R, Hendrickson, W.A.
Deposit date:1995-03-23
Release date:1995-07-10
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis of cell-cell adhesion by cadherins.
Nature, 374, 1995
1NCI
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BU of 1nci by Molmil
STRUCTURAL BASIS OF CELL-CELL ADHESION BY CADHERINS
Descriptor: N-CADHERIN, URANYL (VI) ION
Authors:Shapiro, L, Fannon, A.M, Kwong, P.D, Thompson, A, Lehmann, M.S, Grubel, G, Legrand, J.-F, Als-Nielsen, J, Colman, D.R, Hendrickson, W.A.
Deposit date:1995-03-23
Release date:1995-07-10
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis of cell-cell adhesion by cadherins.
Nature, 374, 1995
1C3H
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BU of 1c3h by Molmil
ACRP30 CALCIUM COMPLEX
Descriptor: 30 KD ADIPOCYTE COMPLEMENT-RELATED PROTEIN PRECURSOR, CALCIUM ION
Authors:Shapiro, L, Boggon, T, Scherer, P.
Deposit date:1999-07-27
Release date:2003-12-09
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:ACRP30 calcium complex
To Be Published
6WUD
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BU of 6wud by Molmil
Human Calcium and Integrin Binding Protein 3 Bound to TMC1 Residues 303-347
Descriptor: Calcium and integrin-binding family member 3, MAGNESIUM ION, Transmembrane channel-like protein 1
Authors:Shapiro, L, Dionne, G.
Deposit date:2020-05-04
Release date:2021-06-23
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:CIB2 and CIB3 are auxiliary subunits of the mechanotransduction channel of hair cells.
Neuron, 109, 2021
6WU7
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BU of 6wu7 by Molmil
Human Calcium and Integrin Binding Protein 3 E150Q K151H
Descriptor: ACETATE ION, CALCIUM ION, Calcium and integrin-binding family member 3
Authors:Shapiro, L, Dionne, G.
Deposit date:2020-05-04
Release date:2021-06-23
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:CIB2 and CIB3 are auxiliary subunits of the mechanotransduction channel of hair cells.
Neuron, 109, 2021
3K6I
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BU of 3k6i by Molmil
Crystal structure of chicken T-cadherin EC1
Descriptor: T-cadherin, ZINC ION
Authors:Shapiro, L, Ciatto, C.
Deposit date:2009-10-08
Release date:2010-03-02
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.13 Å)
Cite:T-cadherin structures reveal a novel adhesive binding mechanism
Nat.Struct.Mol.Biol., 17, 2010
3K5R
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BU of 3k5r by Molmil
Crystal Structure of mouse T-cadherin EC1 EC2
Descriptor: Cadherin 13
Authors:Shapiro, L, Ciatto, C.
Deposit date:2009-10-07
Release date:2010-03-02
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2 Å)
Cite:T-cadherin structures reveal a novel adhesive binding mechanism
Nat.Struct.Mol.Biol., 17, 2010
3K6D
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BU of 3k6d by Molmil
Crystal structure of Xenopus laevis T-cadherin EC1
Descriptor: T-cadherin, ZINC ION
Authors:Shapiro, L, Ciatto, C.
Deposit date:2009-10-08
Release date:2010-03-02
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:T-cadherin structures reveal a novel adhesive binding mechanism
Nat.Struct.Mol.Biol., 17, 2010
3K6F
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BU of 3k6f by Molmil
Crystal structure of mouse T-cadherin EC1
Descriptor: T-cadherin
Authors:Shapiro, L, Ciatto, C.
Deposit date:2009-10-08
Release date:2010-03-02
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.813 Å)
Cite:T-cadherin structures reveal a novel adhesive binding mechanism
Nat.Struct.Mol.Biol., 17, 2010
3K5S
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BU of 3k5s by Molmil
Crystal structure of chicken T-cadherin EC1 EC2
Descriptor: CALCIUM ION, Cadherin-13
Authors:Shapiro, L, Ciatto, C.
Deposit date:2009-10-07
Release date:2010-03-02
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:T-cadherin structures reveal a novel adhesive binding mechanism
Nat.Struct.Mol.Biol., 17, 2010
1C8Z
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BU of 1c8z by Molmil
C-TERMINAL DOMAIN OF MOUSE BRAIN TUBBY PROTEIN
Descriptor: PHOSPHATE ION, TUBBY PROTEIN
Authors:Boggon, T.J, Myers, S.C, Shapiro, L.
Deposit date:1999-07-30
Release date:1999-12-12
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Implication of tubby proteins as transcription factors by structure-based functional analysis.
Science, 286, 1999
2V0G
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BU of 2v0g by Molmil
LEUCYL-TRNA SYNTHETASE FROM THERMUS THERMOPHILUS COMPLEXED WITH A tRNA(leu) transcript with 5-FLUORO-1,3-DIHYDRO-1-HYDROXY-2,1- BENZOXABOROLE (AN2690) forming an adduct to the ribose of adenosine- 76 in the enzyme editing site.
Descriptor: AMINOACYL-TRNA SYNTHETASE, LEUCINE, MERCURY (II) ION, ...
Authors:Rock, F, Mao, W, Yaremchuk, A, Tukalo, M, Crepin, T, Zhou, H, Zhang, Y, Hernandez, V, Akama, T, Baker, S, Plattner, J, Shapiro, L, Martinis, S.A, Benkovic, S.J, Cusack, S, Alley, M.R.K.
Deposit date:2007-05-14
Release date:2007-07-03
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:An Antifungal Agent Inhibits an Aminoacyl-tRNA Synthetase by Trapping tRNA in the Editing Site.
Science, 316, 2007
2V0C
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BU of 2v0c by Molmil
LEUCYL-TRNA SYNTHETASE FROM THERMUS THERMOPHILUS COMPLEXED WITH A SULPHAMOYL ANALOGUE OF LEUCYL-ADENYLATE In the synthetic site and an adduct of AMP with 5-Fluoro-1,3-dihydro-1-hydroxy-2,1-benzoxaborole (AN2690) in the editing site
Descriptor: AMINOACYL-TRNA SYNTHETASE, LEUCINE, SULFATE ION, ...
Authors:Rock, F, Mao, W, Yaremchuk, A, Tukalo, M, Crepin, T, Zhou, H, Zhang, Y, Hernandez, V, Akama, T, Baker, S, Plattner, J, Shapiro, L, Martinis, S.A, Benkovic, S.J, Cusack, S, Alley, M.R.K.
Deposit date:2007-05-14
Release date:2007-07-03
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:An Antifungal Agent Inhibits an Aminoacyl-tRNA Synthetase by Trapping tRNA in the Editing Site.
Science, 316, 2007
7TXD
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BU of 7txd by Molmil
Cryo-EM structure of BG505 SOSIP HIV-1 Env trimer in complex with CD4 receptor (D1D2) and broadly neutralizing darpin bnD.9
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Broadly neutralizing darpin bnd.9, ...
Authors:Cerutti, G, Gorman, J, Kwong, P.D, Shapiro, L.
Deposit date:2022-02-08
Release date:2023-04-12
Last modified:2023-09-27
Method:ELECTRON MICROSCOPY (3.87 Å)
Cite:Trapping the HIV-1 V3 loop in a helical conformation enables broad neutralization.
Nat.Struct.Mol.Biol., 30, 2023
7UKL
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BU of 7ukl by Molmil
Cryo-EM structure of Antibody 12-16 in complex with prefusion SARS-CoV-2 Spike glycoprotein
Descriptor: 12-16 Fab Heavy Chain, 12-16 Fab Light Chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Casner, R.G, Shapiro, L.
Deposit date:2022-04-01
Release date:2023-10-04
Last modified:2023-10-25
Method:ELECTRON MICROSCOPY (3.09 Å)
Cite:Antibodies targeting a quaternary site on SARS-CoV-2 spike glycoprotein prevent viral receptor engagement by conformational locking.
Immunity, 56, 2023
8G4M
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BU of 8g4m by Molmil
Vaccine-elicited human antibody 2C06 in complex with HIV-1 envelope trimer BG505 DS-SOSIP
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp120, ...
Authors:Wang, S, Morano, N.C, Shapiro, L, Kwong, P.D.
Deposit date:2023-02-10
Release date:2023-07-12
Last modified:2023-07-26
Method:ELECTRON MICROSCOPY (2.95 Å)
Cite:HIV-1 neutralizing antibodies elicited in humans by a prefusion-stabilized envelope trimer form a reproducible class targeting fusion peptide.
Cell Rep, 42, 2023
6XEY
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BU of 6xey by Molmil
Cryo-EM structure of the SARS-CoV-2 spike glycoprotein bound to Fab 2-4
Descriptor: 2-4 Heavy Chain, 2-4 Light Chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Rapp, M, Shapiro, L, Ho, D.D.
Deposit date:2020-06-14
Release date:2020-07-22
Last modified:2021-01-27
Method:ELECTRON MICROSCOPY (3.25 Å)
Cite:Potent neutralizing antibodies against multiple epitopes on SARS-CoV-2 spike.
Nature, 584, 2020
8EM4
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BU of 8em4 by Molmil
Cryo-EM structure of LRP2 at pH 7.5
Descriptor: 2-acetamido-2-deoxy-beta-D-galactopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Beenken, A, Cerutti, G, Brasch, J, Fitzpatrick, A.W, Barasch, J, Shapiro, L.
Deposit date:2022-09-26
Release date:2023-02-08
Last modified:2023-03-08
Method:ELECTRON MICROSCOPY (2.83 Å)
Cite:Structures of LRP2 reveal a molecular machine for endocytosis.
Cell, 186, 2023
8EM7
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BU of 8em7 by Molmil
Cryo-EM structure of LRP2 at pH 5.2
Descriptor: 2-acetamido-2-deoxy-beta-D-galactopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Beenken, A, Cerutti, G, Fitzpatrick, A.W, Barasch, J, Shapiro, L.
Deposit date:2022-09-27
Release date:2023-02-08
Last modified:2023-03-08
Method:ELECTRON MICROSCOPY (2.97 Å)
Cite:Structures of LRP2 reveal a molecular machine for endocytosis.
Cell, 186, 2023
7SD5
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BU of 7sd5 by Molmil
Crystallographic structure of neutralizing antibody 10-40 in complex with SARS-CoV-2 spike receptor binding domain
Descriptor: 10-40 Heavy chain, 10-40 Light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Reddem, E.R, Casner, R.G, Shapiro, L.
Deposit date:2021-09-29
Release date:2022-04-27
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.53 Å)
Cite:An antibody class with a common CDRH3 motif broadly neutralizes sarbecoviruses.
Sci Transl Med, 14, 2022
7SI2
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BU of 7si2 by Molmil
Crystal structure of neutralizing antibody 10-28 in complex with SARS-CoV-2 spike receptor binding domain (RBD)
Descriptor: 10-28 Heavy Chain, 10-28 Light Chain, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Reddem, E.R, Shapiro, L.
Deposit date:2021-10-12
Release date:2022-04-27
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:An antibody class with a common CDRH3 motif broadly neutralizes sarbecoviruses.
Sci Transl Med, 14, 2022
7TTX
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BU of 7ttx by Molmil
Crystal structure of potent neutralizing antibody 10-40 in complex with Sarbecovirus bat RaTG13 receptor-binding domain
Descriptor: 1040 heavy chain, 1040 light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Reddem, E.R, Shapiro, L.
Deposit date:2022-02-02
Release date:2022-04-27
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:An antibody class with a common CDRH3 motif broadly neutralizes sarbecoviruses.
Sci Transl Med, 14, 2022

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