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Crystal structure of human CDK8-Cyclin C in complex with cortistatin A
Descriptor:	CORTISTATIN A, CYCLIN-C, CYCLIN-DEPENDENT KINASE 8, ...
Authors:	Myers, A.G, Shair, M.D.
Deposit date:	2014-02-27
Release date:	2015-09-23
Last modified:	2023-12-20
Method:	X-RAY DIFFRACTION (2.4 Å)
Cite:	Mediator Kinase Inhibition Further Activates Super-Enhancer- Associated Genes in Aml Nature, 526, 2015

Co-crystal structure of human NicotinamideN-Methyltransferase (NNMT) in complex with High-Affinity Alkynyl Bisubstrate Inhibitor NS1
Descriptor:	9-{9-amino-6-[(3-carbamoylphenyl)ethynyl]-5,6,7,8,9-pentadeoxy-D-glycero-alpha-L-talo-decofuranuronosyl}-9H-purin-6-amine, GLYCEROL, NNMT protein
Authors:	May, E.J, Policarpo, R.L, Gaudet, R.
Deposit date:	2019-04-30
Release date:	2019-10-23
Last modified:	2023-10-11
Method:	X-RAY DIFFRACTION (2.25 Å)
Cite:	High-Affinity Alkynyl Bisubstrate Inhibitors of NicotinamideN-Methyltransferase (NNMT). J.Med.Chem., 62, 2019