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8AJP
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BU of 8ajp by Molmil
Crystal structure of Halogen methyl transferase from Paraburkholderia xenovorans at 1.8 A in complex with SAH
Descriptor: CHLORIDE ION, Halide methyl transferase, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Leisinger, F, Seebeck, F.P.
Deposit date:2022-07-28
Release date:2022-08-31
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Synthetic Reagents for Enzyme-Catalyzed Methylation.
Angew.Chem.Int.Ed.Engl., 61, 2022
8Q9U
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BU of 8q9u by Molmil
S-methylthiourocanate hydratase, variant R450A, from Variovorax sp. RA8 in complex with NAD+
Descriptor: NICOTINAMIDE-ADENINE-DINUCLEOTIDE, urocanate hydratase
Authors:Vasseur, C.M, Seebeck, F.P.
Deposit date:2023-08-21
Release date:2024-03-06
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure and Substrate Specificity of S -Methyl Thiourocanate Hydratase.
Acs Chem.Biol., 19, 2024
4X8D
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BU of 4x8d by Molmil
Ergothioneine-biosynthetic sulfoxide synthase EgtB in complex with N,N-dimethyl-histidine and gamma-glutamyl-cysteine
Descriptor: CALCIUM ION, CHLORIDE ION, GAMMA-GLUTAMYLCYSTEINE, ...
Authors:Vit, A, Goncharenko, K.V, Blankenfeldt, W, Seebeck, F.P.
Deposit date:2014-12-10
Release date:2015-01-28
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Structure of the Sulfoxide Synthase EgtB from the Ergothioneine Biosynthetic Pathway.
Angew.Chem.Int.Ed.Engl., 54, 2015
7NED
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BU of 7ned by Molmil
Thiourocanate hydratase from Paenibacillus sp. Soil724D2 in complex with cofactor NAD+ and urocanate
Descriptor: (2E)-3-(1H-IMIDAZOL-4-YL)ACRYLIC ACID, 1,2-ETHANEDIOL, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
Authors:Leisinger, F, Seebeck, F.P.
Deposit date:2021-02-03
Release date:2021-02-24
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:In Vitro Reconstitution of a Five-Step Pathway for Bacterial Ergothioneine Catabolism.
Acs Chem.Biol., 16, 2021
5NXL
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BU of 5nxl by Molmil
Formylglycine generating enzyme from T. curvata in complex with Ag(I)
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, CALCIUM ION, ...
Authors:Meury, M, Knop, M, Seebeck, F.P.
Deposit date:2017-05-10
Release date:2017-06-07
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.66 Å)
Cite:Structural Basis for Copper-Oxygen Mediated C-H Bond Activation by the Formylglycine-Generating Enzyme.
Angew. Chem. Int. Ed. Engl., 56, 2017
5NYY
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BU of 5nyy by Molmil
Formylglycine generating enzyme from T. curvata in complex with Cd(II)
Descriptor: (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, ...
Authors:Meury, M, Knop, M, Seebeck, F.P.
Deposit date:2017-05-12
Release date:2017-06-07
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.28 Å)
Cite:Structural Basis for Copper-Oxygen Mediated C-H Bond Activation by the Formylglycine-Generating Enzyme.
Angew. Chem. Int. Ed. Engl., 56, 2017
6XTP
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BU of 6xtp by Molmil
Crystal structure reveals non-coordinative binding of O2 to the copper center of the formylglycine-generating enzyme - FGE:Cu:S:O2-1a complex
Descriptor: ABZ-ALA-THR-THR-PRO-LEU-CYS-GLY-PRO-SER-ARG-ALA-SER-ILE-LEU-SER-GLY, CALCIUM ION, COPPER (I) ION, ...
Authors:Leisinger, F, Seebeck, F.P.
Deposit date:2020-01-16
Release date:2021-01-27
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Non-Coordinative Binding of O2 at the Active Center of a Copper-Dependent Enzyme
Angew.Chem.Int.Ed.Engl., 2020
6XTO
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BU of 6xto by Molmil
Crystal structure reveals non-coordinative binding of O2 to the copper center of the formylglycine-generating enzyme - FGE:Cu:S:NO complex
Descriptor: ABZ-ALA-THR-THR-PRO-LEU-CYS-GLY-PRO-SER-ARG-ALA-SER-ILE-LEU-SER-GLY, CALCIUM ION, COPPER (I) ION, ...
Authors:Leisinger, F, Seebeck, F.P.
Deposit date:2020-01-16
Release date:2021-01-27
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Non-Coordinative Binding of O2 at the Active Center of a Copper-Dependent Enzyme
Angew.Chem.Int.Ed.Engl., 2020
4PIN
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BU of 4pin by Molmil
Ergothioneine-biosynthetic methyltransferase EgtD in complex with N,N-dimethylhistidine
Descriptor: Histidine-specific methyltransferase EgtD, N,N-dimethyl-L-histidine, PHOSPHATE ION
Authors:Vit, A, Seebeck, F.P, Blankenfeldt, W.
Deposit date:2014-05-09
Release date:2014-12-03
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Ergothioneine Biosynthetic Methyltransferase EgtD Reveals the Structural Basis of Aromatic Amino Acid Betaine Biosynthesis.
Chembiochem, 16, 2015
4PIP
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BU of 4pip by Molmil
Engineered EgtD variant EgtD-M252V,E282A in complex with tryptophan and SAH
Descriptor: CHLORIDE ION, Histidine-specific methyltransferase EgtD, MAGNESIUM ION, ...
Authors:Vit, A, Seebeck, F.P, Blankenfeldt, W.
Deposit date:2014-05-09
Release date:2014-12-03
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Ergothioneine Biosynthetic Methyltransferase EgtD Reveals the Structural Basis of Aromatic Amino Acid Betaine Biosynthesis.
Chembiochem, 16, 2015
4PIM
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BU of 4pim by Molmil
Ergothioneine-biosynthetic methyltransferase EgtD, apo form
Descriptor: ACETATE ION, Histidine-specific methyltransferase EgtD
Authors:Vit, A, Seebeck, F.P, Blankenfeldt, W.
Deposit date:2014-05-09
Release date:2014-12-03
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Ergothioneine Biosynthetic Methyltransferase EgtD Reveals the Structural Basis of Aromatic Amino Acid Betaine Biosynthesis.
Chembiochem, 16, 2015
4PIO
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BU of 4pio by Molmil
Ergothioneine-biosynthetic methyltransferase EgtD in complex with N,N-dimethylhistidine and SAH
Descriptor: CHLORIDE ION, Histidine-specific methyltransferase EgtD, MAGNESIUM ION, ...
Authors:Vit, A, Seebeck, F.P, Blankenfeldt, W.
Deposit date:2014-05-09
Release date:2014-12-03
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.506 Å)
Cite:Ergothioneine Biosynthetic Methyltransferase EgtD Reveals the Structural Basis of Aromatic Amino Acid Betaine Biosynthesis.
Chembiochem, 16, 2015
6H99
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BU of 6h99 by Molmil
Crystal structure of anaerobic ergothioneine biosynthesis enzyme from Chlorobium limicola in persulfide form.
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
Authors:Leisinger, F, Burn, R, Meury, M, Lukat, P, Seebeck, F.P.
Deposit date:2018-08-03
Release date:2019-06-12
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural and Mechanistic Basis for Anaerobic Ergothioneine Biosynthesis.
J.Am.Chem.Soc., 141, 2019
6H98
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BU of 6h98 by Molmil
Native crystal structure of anaerobic ergothioneine biosynthesis enzyme from Chlorobium limicola.
Descriptor: CHLORIDE ION, ETHANOL, FORMIC ACID, ...
Authors:Leisinger, F, Burn, R, Meury, M, Lukat, P, Seebeck, F.P.
Deposit date:2018-08-03
Release date:2019-06-12
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural and Mechanistic Basis for Anaerobic Ergothioneine Biosynthesis.
J.Am.Chem.Soc., 141, 2019
6H9A
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BU of 6h9a by Molmil
Crystal structure of anaerobic ergothioneine biosynthesis enzyme from Chlorobium limicola in complex with natural substrate trimethyl histidine.
Descriptor: CHLORIDE ION, N,N,N-trimethyl-histidine, SODIUM ION, ...
Authors:Leisinger, F, Burn, R, Meury, M, Lukat, P, Seebeck, F.P.
Deposit date:2018-08-03
Release date:2019-06-12
Method:X-RAY DIFFRACTION (2.831 Å)
Cite:Structural and Mechanistic Basis for Anaerobic Ergothioneine Biosynthesis.
J.Am.Chem.Soc., 141, 2019
6FNT
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BU of 6fnt by Molmil
Ergothioneine-biosynthetic methyltransferase EgtD in complex with pyrrolidinohistidine
Descriptor: Histidine N-alpha-methyltransferase, Pyrrolidinohistidine
Authors:Vit, A, Blankenfeldt, W, Seebeck, F.P.
Deposit date:2018-02-05
Release date:2018-06-13
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Inhibition and Regulation of the Ergothioneine Biosynthetic Methyltransferase EgtD.
ACS Chem. Biol., 13, 2018
6FNQ
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BU of 6fnq by Molmil
Ergothioneine-biosynthetic methyltransferase EgtD in complex with N,N,N-trimethylhistidine (hercynine)
Descriptor: GLYCEROL, Histidine N-alpha-methyltransferase, MAGNESIUM ION, ...
Authors:Vit, A, Blankenfeldt, W, Seebeck, F.P.
Deposit date:2018-02-05
Release date:2018-06-13
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Inhibition and Regulation of the Ergothioneine Biosynthetic Methyltransferase EgtD.
ACS Chem. Biol., 13, 2018
6FNS
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BU of 6fns by Molmil
Ergothioneine-biosynthetic methyltransferase EgtD in complex with morpholinohistidine
Descriptor: GLYCEROL, Histidine N-alpha-methyltransferase, Morpholinohistidine
Authors:Vit, A, Blankenfeldt, W, Seebeck, F.P.
Deposit date:2018-02-05
Release date:2018-06-13
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Inhibition and Regulation of the Ergothioneine Biosynthetic Methyltransferase EgtD.
ACS Chem. Biol., 13, 2018
6FNR
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BU of 6fnr by Molmil
Ergothioneine-biosynthetic methyltransferase EgtD in complex with chlorohistidine
Descriptor: (2~{S})-2-chloranyl-3-(1~{H}-imidazol-5-yl)propanoic acid, GLYCEROL, Histidine N-alpha-methyltransferase, ...
Authors:Vit, A, Blankenfeldt, W, Seebeck, F.P.
Deposit date:2018-02-05
Release date:2018-06-13
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Inhibition and Regulation of the Ergothioneine Biosynthetic Methyltransferase EgtD.
ACS Chem. Biol., 13, 2018
6XTN
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BU of 6xtn by Molmil
Crystal structure reveals non-coordinative binding of O2 to the copper center of the formylglycine-generating enzyme - FGE:Ag:S:NO complex
Descriptor: 1,2-ETHANEDIOL, Abz-ALA-THR-THR-PRO-LEU-CYS-GLY-PRO-SER-ARG-ALA-SER-ILE-LEU-SER-GLY, CALCIUM ION, ...
Authors:Leisinger, F, Seebeck, F.P.
Deposit date:2020-01-16
Release date:2021-01-27
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Non-Coordinative Binding of O2 at the Active Center of a Copper-Dependent Enzyme
Angew.Chem.Int.Ed.Engl., 2020
6XTL
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BU of 6xtl by Molmil
Crystal structure reveals non-coordinative binding of O2 to the copper center of the formylglycine-generating enzyme - FGE:Ag:S complex
Descriptor: 1,2-ETHANEDIOL, Abz-ALA-THR-THR-PRO-LEU-CYS-GLY-PRO-SER-ARG-ALA-SER-ILE-LEU-SER-GLY, CALCIUM ION, ...
Authors:Leisinger, F, Seebeck, F.P.
Deposit date:2020-01-16
Release date:2021-01-27
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Non-Coordinative Binding of O2 at the Active Center of a Copper-Dependent Enzyme
Angew.Chem.Int.Ed.Engl., 2020
6XTR
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BU of 6xtr by Molmil
Crystal structure reveals non-coordinative binding of O2 to the copper center of the formylglycine-generating enzyme - FGE:Cu:S:O2-1c complex
Descriptor: ABZ-ALA-THR-THR-PRO-LEU-CYS-GLY-PRO-SER-ARG-ALA-SER-ILE-LEU-SER-GLY, CALCIUM ION, CHLORIDE ION, ...
Authors:Leisinger, F, Seebeck, F.P.
Deposit date:2020-01-16
Release date:2021-01-27
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Non-Coordinative Binding of O2 at the Active Center of a Copper-Dependent Enzyme
Angew.Chem.Int.Ed.Engl., 2020
6XTS
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BU of 6xts by Molmil
Crystal structure reveals non-coordinative binding of O2 to the copper center of the formylglycine-generating enzyme - FGE:Cu:S:O2-1d complex
Descriptor: ABZ-ALA-THR-THR-PRO-LEU-CYS-GLY-PRO-SER-ARG-ALA-SER-ILE-LEU-SER-GLY, CALCIUM ION, CHLORIDE ION, ...
Authors:Leisinger, F, Seebeck, F.P.
Deposit date:2020-01-16
Release date:2021-01-27
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Non-Coordinative Binding of O2 at the Active Center of a Copper-Dependent Enzyme
Angew.Chem.Int.Ed.Engl., 2020
6XTQ
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BU of 6xtq by Molmil
Crystal structure reveals non-coordinative binding of O2 to the copper center of the formylglycine-generating enzyme - FGE:Cu:S:O2-1b complex
Descriptor: ABZ-ALA-THR-THR-PRO-LEU-CYS-GLY-PRO-SER-ARG-ALA-SER-ILE-LEU-SER-GLY, CALCIUM ION, CHLORIDE ION, ...
Authors:Leisinger, F, Seebeck, F.P.
Deposit date:2020-01-16
Release date:2021-01-27
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Non-Coordinative Binding of O2 at the Active Center of a Copper-Dependent Enzyme
Angew.Chem.Int.Ed.Engl., 2020
6XTM
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BU of 6xtm by Molmil
Crystal structure reveals non-coordinative binding of O2 to the copper center of the formylglycine-generating enzyme - FGE:Ag:S:O2 complex
Descriptor: Abz-ALA-THR-THR-PRO-LEU-CYS-GLY-PRO-SER-ARG-ALA-SER-ILE-LEU-SER-GLY, CALCIUM ION, CHLORIDE ION, ...
Authors:Leisinger, F, Seebeck, F.P.
Deposit date:2020-01-16
Release date:2021-01-27
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Non-Coordinative Binding of O2 at the Active Center of a Copper-Dependent Enzyme
Angew.Chem.Int.Ed.Engl., 2020

 

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