1Z47 | | STRUCTURE OF THE ATPASE SUBUNIT CYSA OF THE PUTATIVE SULFATE ATP-BINDING CASSETTE (ABC) TRANSPORTER FROM ALICYCLOBACILLUS ACIDOCALDARIUS | | Descriptor: | putative ABC-transporter ATP-binding protein, CHLORIDE ION | | Authors: | Scheffel, F., Demmer, U., Warkentin, E., Huelsmann, A., Schneider, E., Ermler, U. | | Deposit date: | 2005-03-15 | | Release date: | 2005-06-07 | | Last modified: | 2017-10-11 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structure of the ATPase subunit CysA of the putative sulfate ATP-binding cassette (ABC) transporter from Alicyclobacillus acidocaldarius
Febs Lett., 579, 2005
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6GL8 | | CRYSTAL STRUCTURE OF BCL-2 IN COMPLEX WITH THE NOVEL ORALLY ACTIVE INHIBITOR S55746 | | Descriptor: | Apoptosis regulator Bcl-2,Apoptosis regulator Bcl-2,Apoptosis regulator Bcl-2,Bcl-2-like protein 1,Apoptosis regulator Bcl-2,Apoptosis regulator Bcl-2,Apoptosis regulator Bcl-2, ~{N}-(4-hydroxyphenyl)-3-[6-[[(3~{S})-3-(morpholin-4-ylmethyl)-3,4-dihydro-1~{H}-isoquinolin-2-yl]carbonyl]-1,3-benzodioxol-5-yl]-~{N}-phenyl-5,6,7,8-tetrahydroindolizine-1-carboxamide | | Authors: | Casara, P., Davidson, J., Claperon, A., Le Toumelin-Braizat, G., Vogler, M., Bruno, A., Chanrion, M., Lysiak-Auvity, G., Le Diguarher, T., Starck, J.B., Chen, I., Whitehead, N., Graham, C., Matassova, N., Dokurno, P., Pedder, C., Wang, Y., Qiu, S., Girard, A.M., Schneider, E., Grave, F., Studeny, A., Guasconi, G., Rocchetti, F., Maiga, S., Henlin, J.M., Colland, F., Kraus-Berthier, L., Le Gouill, S., Dyer, M.J.S., Hubbard, R., Wood, M., Amiot, M., Cohen, G.M., Hickman, J.A., Morris, E., Murray, J., Geneste, O. | | Deposit date: | 2018-05-23 | | Release date: | 2018-11-07 | | Last modified: | 2018-11-14 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | S55746 is a novel orally active BCL-2 selective and potent inhibitor that impairs hematological tumor growth.
Oncotarget, 9, 2018
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1URD | | X-RAY STRUCTURES OF THE MALTOSE-MALTODEXTRIN BINDING PROTEIN OF THE THERMOACIDOPHILIC BACTERIUM ALICYCLOBACILLUS ACIDOCALDARIUS PROVIDE INSIGHT INTO ACID STABILITY OF PROTEINS | | Descriptor: | MALTOSE-BINDING PROTEIN, MALTOTRIOSE | | Authors: | Schafer, K., Magnusson, U., Scheffel, F., Schiefner, A., Sandgren, M.O.J., Diederichs, K., Welte, W., Hulsmann, A., Schneider, E., Mowbray, S.L. | | Deposit date: | 2003-10-29 | | Release date: | 2003-12-11 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.53 Å) | | Cite: | X-Ray Structures of the Maltose-Maltodextrin-Binding Protein of the Thermoacidophilic Bacterium Alicyclobacillus Acidocaldarius Provide Insight Into Acid Stability of Proteins.
J.Mol.Biol., 335, 2004
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1URG | | X-RAY STRUCTURES FROM THE MALTOSE-MALTODEXTRIN BINDING PROTEIN OF THE THERMOACIDOPHILIC BACTERIUM ALICYCLOBACILLUS ACIDOCALDARIUS | | Descriptor: | MALTOSE-BINDING PROTEIN, MALTOSE | | Authors: | Schafer, K., Magnusson, U., Scheffel, F., Schiefner, A., Sandgren, M.O.J., Diederichs, K., Welte, W., Hulsmann, A., Schneider, E., Mowbray, S.L. | | Deposit date: | 2003-10-29 | | Release date: | 2003-12-11 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | X-Ray Structures of the Maltose-Maltodextrin-Binding Protein of the Thermoacidophilic Bacterium Alicyclobacillus Acidocaldarius Provide Insight Into Acid Stability of Proteins.
J.Mol.Biol., 335, 2004
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1URS | | X-RAY STRUCTURES OF THE MALTOSE-MALTODEXTRIN BINDING PROTEIN OF THE THERMOACIDOPHILIC BACTERIUM ALICYCLOBACILLUS ACIDOCALDARIUS | | Descriptor: | MALTOSE-BINDING PROTEIN, MALTOTRIOSE | | Authors: | Schafer, K., Magnusson, U., Scheffel, F., Schiefner, A., Sandgren, M.O.J., Diederichs, K., Welte, W., Hulsmann, A., Schneider, E., Mowbray, S.L. | | Deposit date: | 2003-11-04 | | Release date: | 2003-12-11 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.45 Å) | | Cite: | X-Ray Structures of the Maltose-Maltodextrin-Binding Protein of the Thermoacidophilic Bacterium Alicyclobacillus Acidocaldarius Provide Insight Into Acid Stability of Proteins
J.Mol.Biol., 335, 2004
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2OLJ | | ABC PROTEIN ARTP IN COMPLEX WITH ADP/MG2+ | | Descriptor: | Amino acid ABC transporter, MAGNESIUM ION, ADENOSINE-5'-DIPHOSPHATE, ... | | Authors: | Thaben, P.F., Eckey, V., Scheffel, F., Saenger, W., Schneider, E., Vahedi-Faridi, A. | | Deposit date: | 2007-01-19 | | Release date: | 2008-01-15 | | Last modified: | 2017-10-18 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | Crystal structures of the ATP-binding cassette (ABC) protein ArtP from Geobacillus stearothermophilus reveal a stable dimer in the post hydrolysis state and an asymmetry in the dimerization region
To be Published
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2OLK | | ABC PROTEIN ARTP IN COMPLEX WITH ADP-BETA-S | | Descriptor: | Amino acid ABC transporter, 5'-O-[(R)-HYDROXY(THIOPHOSPHONOOXY)PHOSPHORYL]ADENOSINE | | Authors: | Thaben, P.F., Eckey, V., Scheffel, F., Saenger, W., Schneider, E., Vahedi-Faridi, A. | | Deposit date: | 2007-01-19 | | Release date: | 2008-01-15 | | Last modified: | 2017-10-18 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Crystal structures of the ATP-binding cassette (ABC) protein ArtP from Geobacillus stearothermophilus reveal a stable dimer in the post hydrolysis state and an asymmetry in the dimerization region
To be Published
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2OUK | | ABC PROTEIN ARTP IN COMPLEX WITH SULPHATE | | Descriptor: | protein ArtP, SULFATE ION | | Authors: | Thaben, P.F., Eckey, V., Scheffel, F., Saenger, W., Schneider, E., Vahedi-Faridi, A. | | Deposit date: | 2007-02-11 | | Release date: | 2008-01-15 | | Last modified: | 2017-10-18 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | Crystal structures of the ATP-binding cassette (ABC) protein ArtP from Geobacillus stearothermophilus reveal a stable dimer in the post hydrolysis state and an asymmetry in the dimerization region
To be Published
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2PVU | | CRYSTAL STRUCTURES OF THE ARGININE-, LYSINE-, HISTIDINE-BINDING PROTEIN ARTJ FROM THE THERMOPHILIC BACTERIUM GEOBACILLUS STEAROTHERMOPHILUS | | Descriptor: | ArtJ, SULFATE ION, LYSINE | | Authors: | Vahedi-Faridi, A., Scheffel, F., Eckey, V., Saenger, W., Schneider, E. | | Deposit date: | 2007-05-10 | | Release date: | 2008-01-15 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.79 Å) | | Cite: | Crystal structures and mutational analysis of the arginine-, lysine-, histidine-binding protein ArtJ from Geobacillus stearothermophilus. Implications for interactions of ArtJ with its cognate ATP-binding cassette transporter, Art(MP)2
J.Mol.Biol., 375, 2008
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2Q0H | | ABC PROTEIN ARTP IN COMPLEX WITH ADP/MG2+, ATP-GAMMA-S HYDROLYZED | | Descriptor: | ArtP, MAGNESIUM ION, ADENOSINE-5'-DIPHOSPHATE, ... | | Authors: | Thaben, P.F., Eckey, V., Scheffel, F., Saenger, W., Schneider, E., Vahedi-Faridi, A. | | Deposit date: | 2007-05-22 | | Release date: | 2008-06-10 | | Last modified: | 2017-10-18 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Crystal structures of the ATP-binding cassette (ABC) protein ArtP from Geobacillus stearothermophilus reveal a stable dimer in the post hydrolysis state and an asymmetry in the dimerization region
To be Published
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2Q2A | | CRYSTAL STRUCTURES OF THE ARGININE-, LYSINE-, HISTIDINE-BINDING PROTEIN ARTJ FROM THE THERMOPHILIC BACTERIUM GEOBACILLUS STEAROTHERMOPHILUS | | Descriptor: | ArtJ, SULFATE ION, ARGININE | | Authors: | Vahedi-Faridi, A., Scheffel, F., Eckey, V., Saenger, W., Schneider, E. | | Deposit date: | 2007-05-26 | | Release date: | 2008-01-15 | | Last modified: | 2017-10-18 | | Method: | X-RAY DIFFRACTION (1.79 Å) | | Cite: | Crystal structures and mutational analysis of the arginine-, lysine-, histidine-binding protein ArtJ from Geobacillus stearothermophilus. Implications for interactions of ArtJ with its cognate ATP-binding cassette transporter, Art(MP)2
J.Mol.Biol., 375, 2008
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2Q2C | | CRYSTAL STRUCTURES OF THE ARGININE-, LYSINE-, HISTIDINE-BINDING PROTEIN ARTJ FROM THE THERMOPHILIC BACTERIUM GEOBACILLUS STEAROTHERMOPHILUS | | Descriptor: | ArtJ, SULFATE ION, HISTIDINE, ... | | Authors: | Vahedi-Faridi, A., Scheffel, F., Eckey, V., Saenger, W., Schneider, E. | | Deposit date: | 2007-05-28 | | Release date: | 2008-01-15 | | Last modified: | 2017-10-18 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | Crystal structures and mutational analysis of the arginine-, lysine-, histidine-binding protein ArtJ from Geobacillus stearothermophilus. Implications for interactions of ArtJ with its cognate ATP-binding cassette transporter, Art(MP)2
J.Mol.Biol., 375, 2008
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2YJP | | CRYSTAL STRUCTURE OF THE SOLUTE RECEPTORS FOR L-CYSTEINE OF NEISSERIA GONORRHOEAE | | Descriptor: | PUTATIVE ABC TRANSPORTER, PERIPLASMIC BINDING PROTEIN, AMINO ACID, ... | | Authors: | Bulut, H., Moniot, S., Scheffel, F., Gathmann, S., Licht, A., Saenger, W., Schneider, E. | | Deposit date: | 2011-05-23 | | Release date: | 2011-12-14 | | Last modified: | 2012-01-25 | | Method: | X-RAY DIFFRACTION (2.26 Å) | | Cite: | Crystal Structures of Two Solute Receptors for L-Cystine and L-Cysteine, Respectively, of the Human Pathogen Neisseria Gonorrhoeae.
J.Mol.Biol., 415, 2012
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2YLN | | CRYSTAL STRUCTURE OF THE L-CYSTINE SOLUTE RECEPTOR OF NEISSERIA GONORRHOEAE IN THE CLOSED CONFORMATION | | Descriptor: | PUTATIVE ABC TRANSPORTER, PERIPLASMIC BINDING PROTEIN, AMINO ACID, ... | | Authors: | Bulut, H., Moniot, S., Scheffel, F., Gathmann, S., Licht, A., Saenger, W., Schneider, E. | | Deposit date: | 2011-06-03 | | Release date: | 2011-12-14 | | Last modified: | 2012-01-25 | | Method: | X-RAY DIFFRACTION (1.12 Å) | | Cite: | Crystal Structures of Two Solute Receptors for L-Cystine and L-Cysteine, Respectively, of the Human Pathogen Neisseria Gonorrhoeae.
J.Mol.Biol., 415, 2012
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3C41 | | ABC PROTEIN ARTP IN COMPLEX WITH AMP-PNP/MG2+ | | Descriptor: | Amino acid ABC transporter (ArtP), MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | | Authors: | Thaben, P.F., Eckey, V., Scheffel, F., Saenger, W., Schneider, E., Vahedi-Faridi, A. | | Deposit date: | 2008-01-29 | | Release date: | 2009-02-03 | | Last modified: | 2017-10-25 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | Crystal Structures of the ATP-binding cassette (ABC) Protein ArtP from Geobacillus stearothermophilus in complexes with nucleotides and nucleotide analogs reveal an intermediate semiclosed dimer in the post hydrolyses state and an asymmetry in the dimerisation region
To be Published
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3C4J | | ABC PROTEIN ARTP IN COMPLEX WITH ATP-GAMMA-S | | Descriptor: | Amino acid ABC transporter (ArtP), MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER | | Authors: | Thaben, P.F., Eckey, V., Scheffel, F., Saenger, W., Schneider, E., Vahedi-Faridi, A. | | Deposit date: | 2008-01-30 | | Release date: | 2009-02-03 | | Last modified: | 2017-10-25 | | Method: | X-RAY DIFFRACTION (2.33 Å) | | Cite: | Crystal Structures of the ATP-binding cassette (ABC) Protein ArtP from Geobacillus stearothermophilus in complexes with nucleotides and nucleotide analogs reveal an intermediate semiclosed dimer in the post hydrolyses state and an asymmetry in the dimerisation region
To be Published
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3JYR | | CRYSTAL STRUCTURES OF THE GACH RECEPTOR OF STREPTOMYCES GLAUCESCENS GLA.O IN THE UNLIGANDED FORM AND IN COMPLEX WITH ACARBOSE AND AN ACARBOSE HOMOLOG. COMPARISON WITH ACARBOSE-LOADED MALTOSE BINDING PROTEIN OF SALMONELLA TYPHIMURIUM. | | Descriptor: | Maltose-binding periplasmic protein, ALPHA-ACARBOSE | | Authors: | Vahedi-Faridi, A., Licht, A., Bulut, H., Schneider, E. | | Deposit date: | 2009-09-22 | | Release date: | 2010-02-16 | | Last modified: | 2017-11-01 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Crystal Structures of the Solute Receptor GacH of Streptomyces glaucescens in Complex with Acarbose and an Acarbose Homolog: Comparison with the Acarbose-Loaded Maltose-Binding Protein of Salmonella typhimurium.
J.Mol.Biol., 397, 2010
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3JZJ | | CRYSTAL STRUCTURES OF THE GACH RECEPTOR OF STREPTOMYCES GLAUCESCENS GLA.O IN THE UNLIGANDED FORM AND IN COMPLEX WITH ACARBOSE AND AN ACARBOSE HOMOLOG. COMPARISON WITH ACARBOSE-LOADED MALTOSE BINDING PROTEIN OF SALMONELLA TYPHIMURIUM. | | Descriptor: | Acarbose/maltose binding protein GacH, ALPHA-ACARBOSE, SULFATE ION | | Authors: | Vahedi-Faridi, A., Licht, A., Bulut, H., Schneider, E. | | Deposit date: | 2009-09-23 | | Release date: | 2010-02-16 | | Last modified: | 2017-11-01 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | Crystal Structures of the Solute Receptor GacH of Streptomyces glaucescens in Complex with Acarbose and an Acarbose Homolog: Comparison with the Acarbose-Loaded Maltose-Binding Protein of Salmonella typhimurium.
J.Mol.Biol., 397, 2010
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3K00 | | CRYSTAL STRUCTURES OF THE GACH RECEPTOR OF STREPTOMYCES GLAUCESCENS GLA.O IN THE UNLIGANDED FORM AND IN COMPLEX WITH ACARBOSE AND AN ACARBOSE HOMOLOG. COMPARISON WITH ACARBOSE-LOADED MALTOSE BINDING PROTEIN OF SALMONELLA TYPHIMURIUM. | | Descriptor: | Acarbose/maltose binding protein GacH, MALTOTETRAOSE | | Authors: | Vahedi-Faridi, A., Licht, A., Bulut, H., Schneider, E. | | Deposit date: | 2009-09-24 | | Release date: | 2010-02-16 | | Last modified: | 2017-11-01 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | Crystal Structures of the Solute Receptor GacH of Streptomyces glaucescens in Complex with Acarbose and an Acarbose Homolog: Comparison with the Acarbose-Loaded Maltose-Binding Protein of Salmonella typhimurium.
J.Mol.Biol., 397, 2010
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3K01 | | CRYSTAL STRUCTURES OF THE GACH RECEPTOR OF STREPTOMYCES GLAUCESCENS GLA.O IN THE UNLIGANDED FORM AND IN COMPLEX WITH ACARBOSE AND AN ACARBOSE HOMOLOG. COMPARISON WITH ACARBOSE-LOADED MALTOSE BINDING PROTEIN OF SALMONELLA TYPHIMURIUM. | | Descriptor: | Acarbose/maltose binding protein GacH, SULFATE ION | | Authors: | Vahedi-Faridi, A., Licht, A., Bulut, H., Schneider, E. | | Deposit date: | 2009-09-24 | | Release date: | 2010-02-16 | | Last modified: | 2017-11-01 | | Method: | X-RAY DIFFRACTION (1.35 Å) | | Cite: | Crystal Structures of the Solute Receptor GacH of Streptomyces glaucescens in Complex with Acarbose and an Acarbose Homolog: Comparison with the Acarbose-Loaded Maltose-Binding Protein of Salmonella typhimurium.
J.Mol.Biol., 397, 2010
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3K02 | | CRYSTAL STRUCTURES OF THE GACH RECEPTOR OF STREPTOMYCES GLAUCESCENS GLA.O IN THE UNLIGANDED FORM AND IN COMPLEX WITH ACARBOSE AND AN ACARBOSE HOMOLOG. COMPARISON WITH ACARBOSE-LOADED MALTOSE BINDING PROTEIN OF SALMONELLA TYPHIMURIUM. | | Descriptor: | Acarbose/maltose binding protein GacH, 4,6-dideoxy-4-{[(1S,2R,3R,4S,5S)-2,3,4-trihydroxy-5-(hydroxymethyl)cyclohexyl]amino}-alpha-D-allopyranosyl-(1->4)-alpha-D-glucopyranosyl-(1->4)-alpha-D-glucopyranosyl-(1->4)-alpha-D-glucopyranose, SULFATE ION | | Authors: | Vahedi-Faridi, A., Licht, A., Bulut, H., Schneider, E. | | Deposit date: | 2009-09-24 | | Release date: | 2010-02-16 | | Last modified: | 2017-11-01 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | Crystal Structures of the Solute Receptor GacH of Streptomyces glaucescens in Complex with Acarbose and an Acarbose Homolog: Comparison with the Acarbose-Loaded Maltose-Binding Protein of Salmonella typhimurium.
J.Mol.Biol., 397, 2010
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3ZSF | | CRYSTAL STRUCTURE OF THE L-CYSTINE SOLUTE RECEPTOR OF NEISSERIA GONORRHOEAE IN THE UNLIGANDED OPEN CONFORMATION | | Descriptor: | ABC TRANSPORTER, PERIPLASMIC BINDING PROTEIN, AMINO ACID | | Authors: | Bulut, H., Moniot, S., Scheffel, F., Gathmann, S., Licht, A., Saenger, W., Schneider, E. | | Deposit date: | 2011-06-27 | | Release date: | 2011-12-14 | | Last modified: | 2012-01-25 | | Method: | X-RAY DIFFRACTION (2.32 Å) | | Cite: | Crystal Structures of Two Solute Receptors for L-Cystine and L-Cysteine, Respectively, of the Human Pathogen Neisseria Gonorrhoeae.
J.Mol.Biol., 415, 2012
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4AQ4 | | SUBSTRATE BOUND SN-GLYCEROL-3-PHOSPHATE BINDING PERIPLASMIC PROTEIN UGPB FROM ESCHERICHIA COLI | | Descriptor: | SN-GLYCEROL-3-PHOSPHATE-BINDING PERIPLASMIC PROTEIN UGPB, SN-GLYCEROL-3-PHOSPHATE, GLYCEROL, ... | | Authors: | Wuttge, S., Bommer, M., Jaeger, F., Martins, B.M., Jacob, S., Licht, A., Scheffel, F., Dobbek, H., Schneider, E. | | Deposit date: | 2012-04-13 | | Release date: | 2012-10-17 | | Last modified: | 2019-03-06 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Determinants of Substrate Specificity and Biochemical Properties of the Sn-Glycerol-3-Phosphate ATP Binding Cassette Transporter (Ugpb-Aec(2) ) of Escherichia Coli.
Mol.Microbiol., 86, 2012
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5M28 | | MALTODEXTRIN BINDING PROTEIN MALE1 FROM L. CASEI BL23 BOUND TO MALTOTRIOSE | | Descriptor: | MalE1, MALTOTRIOSE, CHLORIDE ION | | Authors: | Homburg, C., Bommer, M., Wuttge, S., Hobe, C., Beck, S., Dobbek, H., Deutscher, J., Licht, A., Schneider, E. | | Deposit date: | 2016-10-12 | | Release date: | 2017-07-05 | | Method: | X-RAY DIFFRACTION (1.079 Å) | | Cite: | Inducer exclusion in Firmicutes: insights into the regulation of a carbohydrate ATP binding cassette transporter from Lactobacillus casei BL23 by the signal transducing protein P-Ser46-HPr.
Mol. Microbiol., 105, 2017
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5MK9 | | MALTODEXTRIN BINDING PROTEIN MALE1 FROM L. CASEI BL23 BOUND TO BETA-CYCLODEXTRIN | | Descriptor: | MalE1, BETA-CYCLODEXTRIN, CHLORIDE ION | | Authors: | Homburg, C., Bommer, M., Wuttge, S., Hobe, C., Beck, S., Dobbek, H., Deutscher, J., Licht, A., Schneider, E. | | Deposit date: | 2016-12-02 | | Release date: | 2017-07-05 | | Method: | X-RAY DIFFRACTION (0.919 Å) | | Cite: | Inducer exclusion in Firmicutes: insights into the regulation of a carbohydrate ATP binding cassette transporter from Lactobacillus casei BL23 by the signal transducing protein P-Ser46-HPr.
Mol. Microbiol., 105, 2017
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