Author results

1PYB
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CRYSTAL STRUCTURE OF AQUIFEX AEOLICUS TRBP111: A STRUCTURE-SPECIFIC TRNA BINDING PROTEIN
Descriptor:methionyl-tRNA synthetase beta subunit
Authors:Swairjo, M.A., Morales, A.J., Wang, C.C., Ortiz, A.R., Schimmel, P.
Deposit date:2003-07-08
Release date:2003-08-05
Last modified:2017-02-01
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal Structure of Trbp111: a Strcuture-Specific tRNA-Binding Protein
Embo J., 19, 2000
3HTZ
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CRYSTAL STRUCTURE OF THE CATALYTIC FRAGMENT OF ALANYL-TRNA SYNTHETASE IN COMPLEX WITH L-SERINE: RE-REFINED
Descriptor:Alanyl-tRNA synthetase
Authors:Guo, M., Swairjo, M.A., Schimmel, P.
Deposit date:2009-06-12
Release date:2009-06-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Serine Paradox
To be Published
1ILE
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ISOLEUCYL-TRNA SYNTHETASE
Descriptor:ISOLEUCYL-TRNA SYNTHETASE, ZINC ION
Authors:Nureki, O., Vassylyev, D.G., Tateno, M., Shimada, A., Nakama, T., Fukai, S., Konno, M., Schimmel, P., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:1998-02-24
Release date:1999-04-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Enzyme structure with two catalytic sites for double-sieve selection of substrate.
Science, 280, 1998
1N3L
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CRYSTAL STRUCTURE OF A HUMAN AMINOACYL-TRNA SYNTHETASE CYTOKINE
Descriptor:tyrosyl-tRNA synthetase, SULFATE ION, GLYCEROL
Authors:Yang, X.-L., Skene, R.J., McRee, D.E., Schimmel, P.
Deposit date:2002-10-28
Release date:2002-11-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.18 Å)
Cite:Crystal structure of a human aminoacyl-tRNA synthetase cytokine
Proc.Natl.Acad.Sci.USA, 99, 2002
1NTG
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CRYSTAL STRUCTURE OF THE EMAP II-LIKE CYTOKINE RELEASED FROM HUMAN TYROSYL-TRNA SYNTHETASE
Descriptor:Tyrosyl-tRNA synthetase
Authors:Yang, X.-L., Skene, R.J., Mcree, D.E., Schimmel, P.
Deposit date:2003-01-29
Release date:2003-05-13
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:Crystal Structure of an EMAP-II-like Cytokine Released from a human tRNA Synthetase
Helv.Chim.Acta, 86, 2003
1Q11
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CRYSTAL STRUCTURE OF AN ACTIVE FRAGMENT OF HUMAN TYROSYL-TRNA SYNTHETASE WITH TYROSINOL
Descriptor:Tyrosyl-tRNA synthetase, PHOSPHATE ION, POTASSIUM ION, ...
Authors:Yang, X.-L., Schimmel, P., Ribas de Pouplana, L.
Deposit date:2003-07-18
Release date:2004-01-06
Last modified:2018-10-17
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal structures that suggest late development of genetic code components for differentiating aromatic side chains
Proc.Natl.Acad.Sci.USA, 100, 2003
1Q7S
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CRYSTAL STRUCTURE OF BIT1
Descriptor:bit1
Authors:De Pereda, J.M., Waas, W.F., Jan, Y., Ruoslahti, E., Schimmel, P., Pascual, J.
Deposit date:2003-08-19
Release date:2003-12-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of a human peptidyl-tRNA hydrolase reveals a new fold and suggests basis for a bifunctional activity.
J.Biol.Chem., 279, 2004
1R6T
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CRYSTAL STRUCTURE OF HUMAN TRYPTOPHANYL-TRNA SYNTHETASE
Descriptor:Tryptophanyl-tRNA synthetase, TRYPTOPHANYL-5'AMP, GLYCEROL
Authors:Yang, X.-L., Otero, F.J., Skene, R.J., McRee, D.E., Ribas de Pouplana, L., Schimmel, P.
Deposit date:2003-10-16
Release date:2004-01-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structures that suggest late development of genetic code components for differentiating aromatic side chains
Proc.Natl.Acad.Sci.USA, 100, 2003
1R6U
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CRYSTAL STRUCTURE OF AN ACTIVE FRAGMENT OF HUMAN TRYPTOPHANYL-TRNA SYNTHETASE WITH CYTOKINE ACTIVITY
Descriptor:Tryptophanyl-tRNA synthetase, TRYPTOPHANYL-5'AMP, GLYCEROL
Authors:Yang, X.-L., Otero, F.J., Skene, R.J., McRee, D.E., Ribas de Pouplana, L., Schimmel, P.
Deposit date:2003-10-16
Release date:2004-01-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Functional and crystal structure analysis of active site adaptations of a potent anti-angiogenic human tRNA synthetase
Structure, 15, 2007
1RIQ
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THE CRYSTAL STRUCTURE OF THE CATALYTIC FRAGMENT OF THE ALANYL-TRNA SYNTHETASE
Descriptor:Alanyl-tRNA synthetase
Authors:Swairjo, M.A., Otero, F.J., Yang, X.-L., Lovato, M.A., Skene, R.J., McRee, D.E., Ribas de Pouplana, L., Schimmel, P.
Deposit date:2003-11-17
Release date:2004-04-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:Alanyl-tRNA Synthetase Crystal Structure and Design for Acceptor-Stem Recognition
Mol.Cell, 13, 2004
2AZX
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CHARGED AND UNCHARGED TRNAS ADOPT DISTINCT CONFORMATIONS WHEN COMPLEXED WITH HUMAN TRYPTOPHANYL-TRNA SYNTHETASE
Descriptor:72-MER, Tryptophanyl-tRNA synthetase, SULFATE ION, ...
Authors:Yang, X.L., Otero, F.J., Ewalt, K.L., Liu, J., Swairjo, M.A., Kohrer, C., RajBhandary, U.L., Skene, R.J., McRee, D.E., Schimmel, P.
Deposit date:2005-09-12
Release date:2006-08-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Two conformations of a crystalline human tRNA synthetase-tRNA complex: implications for protein synthesis.
Embo J., 25, 2006
2LW7
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NMR SOLUTION STRUCTURE OF HUMAN HISRS SPLICE VARIANT
Descriptor:Histidine--tRNA ligase, cytoplasmic
Authors:Ye, F., Wei, Z., Wu, J., Schimmel, P., Zhang, M.
Deposit date:2012-07-24
Release date:2013-09-04
Method:SOLUTION NMR
Cite:NMR solution structure of human HisRS splice variant
To be Published
3BJU
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CRYSTAL STRUCTURE OF TETRAMERIC FORM OF HUMAN LYSYL-TRNA SYNTHETASE
Descriptor:Lysyl-tRNA synthetase, CALCIUM ION, LYSINE, ...
Authors:Guo, M., Yang, X.L., Schimmel, P.
Deposit date:2007-12-04
Release date:2008-02-05
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:Crystal structure of tetrameric form of human lysyl-tRNA synthetase: Implications for multisynthetase complex formation
Proc.Natl.Acad.Sci.Usa, 105, 2008
3G98
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CRYSTAL STRUCTURE OF THE C-ALA DOMAIN FROM AQUIFEX AEOLICUS ALANYL-TRNA SYNTHETASE
Descriptor:Alanyl-tRNA synthetase
Authors:Guo, M., Yang, X.L., Schimmel, P.
Deposit date:2009-02-13
Release date:2009-10-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:The C-Ala domain brings together editing and aminoacylation functions on one tRNA.
Science, 325, 2009
3HXU
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CRYSTAL STRUCTURE OF CATALYTIC FRAGMENT OF E. COLI ALARS IN COMPLEX WITH ALASA
Descriptor:Alanyl-tRNA synthetase, '5'-O-(N-(L-ALANYL)-SULFAMOYL)ADENOSINE, 2-HYDROXYETHYL DISULFIDE, ...
Authors:Guo, M., Yang, X.-L., Schimmel, P.
Deposit date:2009-06-22
Release date:2009-12-15
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Paradox of mistranslation of serine for alanine caused by AlaRS recognition dilemma.
Nature, 462, 2009
3HXV
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CRYSTAL STRUCTURE OF CATALYTIC FRAGMENT OF E. COLI ALARS IN COMPLEX WITH GLYSA
Descriptor:Alanyl-tRNA synthetase, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 2-HYDROXYETHYL DISULFIDE, ...
Authors:Guo, M., Yang, X.-L., Schimmel, P.
Deposit date:2009-06-22
Release date:2009-12-15
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Paradox of mistranslation of serine for alanine caused by AlaRS recognition dilemma.
Nature, 462, 2009
3HXW
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CRYSTAL STRUCTURE OF CATALYTIC FRAGMENT OF E. COLI ALARS IN COMPLEX WITH SERSA
Descriptor:Alanyl-tRNA synthetase, 5'-O-(N-(L-SERYL)-SULFAMOYL)ADENOSINE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ...
Authors:Guo, M., Yang, X.-L., Schimmel, P.
Deposit date:2009-06-22
Release date:2009-12-15
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Paradox of mistranslation of serine for alanine caused by AlaRS recognition dilemma.
Nature, 462, 2009
3HXX
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CRYSTAL STRUCTURE OF CATALYTIC FRAGMENT OF E. COLI ALARS IN COMPLEX WITH AMPPCP
Descriptor:Alanyl-tRNA synthetase, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, MAGNESIUM ION
Authors:Guo, M., Yang, X.-L., Schimmel, P.
Deposit date:2009-06-22
Release date:2009-12-15
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.11 Å)
Cite:Paradox of mistranslation of serine for alanine caused by AlaRS recognition dilemma.
Nature, 462, 2009
3HXY
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CRYSTAL STRUCTURE OF CATALYTIC FRAGMENT OF E. COLI ALARS IN COMPLEX WITH AMPPCP, ALA-AMP AND PCP
Descriptor:Alanyl-tRNA synthetase, 5'-O-[(R)-{[(2S)-2-aminopropanoyl]oxy}(hydroxy)phosphoryl]adenosine, METHYLENEDIPHOSPHONIC ACID, ...
Authors:Guo, M., Yang, X.-L., Schimmel, P.
Deposit date:2009-06-22
Release date:2009-12-15
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:Paradox of mistranslation of serine for alanine caused by AlaRS recognition dilemma.
Nature, 462, 2009
3HXZ
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CRYSTAL STRUCTURE OF CATALYTIC FRAGMENT OF E. COLI ALARS G237A IN COMPLEX WITH ALASA
Descriptor:Alanyl-tRNA synthetase, '5'-O-(N-(L-ALANYL)-SULFAMOYL)ADENOSINE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ...
Authors:Guo, M., Yang, X.-L., Schimmel, P.
Deposit date:2009-06-22
Release date:2009-12-15
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Paradox of mistranslation of serine for alanine caused by AlaRS recognition dilemma.
Nature, 462, 2009
3HY0
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CRYSTAL STRUCTURE OF CATALYTIC FRAGMENT OF E. COLI ALARS G237A IN COMPLEX WITH GLYSA
Descriptor:Alanyl-tRNA synthetase, 5'-O-(glycylsulfamoyl)adenosine, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ...
Authors:Guo, M., Yang, X.-L., Schimmel, P.
Deposit date:2009-06-22
Release date:2009-12-15
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Paradox of mistranslation of serine for alanine caused by AlaRS recognition dilemma.
Nature, 462, 2009
3HY1
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CRYSTAL STRUCTURE OF CATALYTIC FRAGMENT OF E. COLI ALARS G237A IN COMPLEX WITH SERSA
Descriptor:Alanyl-tRNA synthetase, 5'-O-(N-(L-SERYL)-SULFAMOYL)ADENOSINE, 2-HYDROXYETHYL DISULFIDE, ...
Authors:Guo, M., Yang, X.-L., Schimmel, P.
Deposit date:2009-06-22
Release date:2009-12-15
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.79 Å)
Cite:Paradox of mistranslation of serine for alanine caused by AlaRS recognition dilemma.
Nature, 462, 2009
4G84
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CRYSTAL STRUCTURE OF HUMAN HISRS
Descriptor:Histidine--tRNA ligase, cytoplasmic, IMIDAZOLE, ...
Authors:Wei, Z., Wu, J., Zhou, J.J., Yang, X.-L., Zhang, M., Schimmel, P.
Deposit date:2012-07-21
Release date:2012-09-26
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Internally Deleted Human tRNA Synthetase Suggests Evolutionary Pressure for Repurposing.
Structure, 20, 2012
4G85
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CRYSTAL STRUCTURE OF HUMAN HISRS
Descriptor:Histidine-tRNA ligase, cytoplasmic
Authors:Wei, Z., Wu, J., Zhou, J.J., Yang, X.-L., Zhang, M., Schimmel, P.
Deposit date:2012-07-21
Release date:2012-09-26
Method:X-RAY DIFFRACTION (3.11 Å)
Cite:Internally Deleted Human tRNA Synthetase Suggests Evolutionary Pressure for Repurposing.
Structure, 20, 2012
4HVC
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CRYSTAL STRUCTURE OF HUMAN PROLYL-TRNA SYNTHETASE IN COMPLEX WITH HALOFUGINONE AND ATP ANALOGUE
Descriptor:Bifunctional glutamate/proline--tRNA ligase, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, 7-bromo-6-chloro-3-{3-[(2R,3S)-3-hydroxypiperidin-2-yl]-2-oxopropyl}quinazolin-4(3H)-one, ...
Authors:Zhou, H., Sun, L., Yang, X.L., Schimmel, P.
Deposit date:2012-11-06
Release date:2013-01-02
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2 Å)
Cite:ATP-directed capture of bioactive herbal-based medicine on human tRNA synthetase.
Nature, 494, 2012
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