Author results

1EST
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THE ATOMIC STRUCTURE OF CRYSTALLINE PORCINE PANCREATIC ELASTASE AT 2.5 ANGSTROMS RESOLUTION. COMPARISONS WITH THE STRUCTURE OF ALPHA-CHYMOTRYPSIN
Descriptor:PORCINE PANCREATIC ELASTASE, SULFATE ION, PARA-TOLUENE SULFONATE
Authors:Sawyer, L., Shotton, D.M., Watson, H.C.
Deposit date:1976-05-17
Release date:1976-05-27
Last modified:2011-08-24
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The atomic structure of crystalline porcine pancreatic elastase at 2.5 A resolution: comparisons with the structure of alpha-chymotrypsin.
J.Mol.Biol., 118, 1978
1DBS
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MECHANISTIC IMPLICATIONS AND FAMILY RELATIONSHIPS FROM THE STRUCTURE OF DETHIOBIOTIN SYNTHETASE
Descriptor:DETHIOBIOTIN SYNTHETASE, SULFATE ION
Authors:Sawyer, L., Alexeev, D.
Deposit date:1994-11-29
Release date:1995-04-20
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Mechanistic implications and family relationships from the structure of dethiobiotin synthetase.
Structure, 2, 1994
1UZ2
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THE CYS121SER MUTANT OF BETA-LACTOGLOBULIN
Descriptor:BETA-LACTOGLOBULIN
Authors:McNae, I., Jayat, D., Haertle, T., Holt, C., Sawyer, L.
Deposit date:2004-03-03
Release date:2004-05-20
Last modified:2019-01-16
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:A recombinant C121S mutant of bovine beta-lactoglobulin is more susceptible to peptic digestion and to denaturation by reducing agents and heating.
Biochemistry, 43, 2004
1DV9
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STRUCTURAL CHANGES ACCOMPANYING PH-INDUCED DISSOCIATION OF THE B-LACTOGLOBULIN DIMER
Descriptor:BETA-LACTOGLOBULIN
Authors:Uhrinova, S., Smith, M.H., Jameson, G.B., Uhrin, D., Sawyer, L., Barlow, P.N.
Deposit date:2000-01-20
Release date:2000-02-09
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structural changes accompanying pH-induced dissociation of the beta-lactoglobulin dimer.
Biochemistry, 39, 2000
1OGW
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SYNTHETIC UBIQUITIN WITH FLUORO-LEU AT 50 AND 67
Descriptor:UBIQUITIN
Authors:Alexeev, D., Ramage, R., Young, D.W., Sawyer, L.
Deposit date:2003-05-13
Release date:2003-05-30
Last modified:2011-12-07
Method:X-RAY DIFFRACTION (1.32 Å)
Cite:Synthesis, Structural and Biological Studies of Ubiquitin Mutants Containing (2S, 4S)-5-Fluoroleucine Residues Strategically Placed in the Hydrophobic Core
Chembiochem, 4, 2003
1B0O
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BOVINE BETA-LACTOGLOBULIN COMPLEXED WITH PALMITATE, LATTICE Z
Descriptor:BETA-LACTOGLOBULIN, PALMITIC ACID
Authors:Wu, S.-Y., Sawyer, L.
Deposit date:1998-11-11
Release date:1999-02-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:beta-lactoglobulin binds palmitate within its central cavity.
J.Biol.Chem., 274, 1999
1DJ9
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CRYSTAL STRUCTURE OF 8-AMINO-7-OXONANOATE SYNTHASE (OR 7-KETO-8AMINIPELARGONATE OR KAPA SYNTHASE) COMPLEXED WITH PLP AND THE PRODUCT 8(S)-AMINO-7-OXONANONOATE (OR KAPA). THE ENZYME OF BIOTIN BIOSYNTHETIC PATHWAY.
Descriptor:8-AMINO-7-OXONONANOATE SYNTHASE, SULFATE ION, MAGNESIUM ION, ...
Authors:Webster, S.P., Alexeev, D., Campopiano, D.J., Watt, R.M., Alexeeva, M., Sawyer, L., Baxter, R.L.
Deposit date:1999-12-02
Release date:2000-12-06
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2 Å)
Cite:Mechanism of 8-amino-7-oxononanoate synthase: spectroscopic, kinetic, and crystallographic studies.
Biochemistry, 39, 2000
1DJE
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CRYSTAL STRUCTURE OF THE PLP-BOUND FORM OF 8-AMINO-7-OXONANOATE SYNTHASE
Descriptor:8-AMINO-7-OXONANOATE SYNTHASE, SULFATE ION, PYRIDOXAL-5'-PHOSPHATE
Authors:Webster, S.P., Alexeev, D., Campopiano, D.J., Watt, R.M., Alexeeva, M., Sawyer, L., Baxter, R.L.
Deposit date:1999-12-02
Release date:2000-12-04
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.71 Å)
Cite:Mechanism of 8-amino-7-oxononanoate synthase: spectroscopic, kinetic, and crystallographic studies.
Biochemistry, 39, 2000
1GXA
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BOVINE BETA-LACTOGLOBULIN COMPLEXED WITH RETINOL AND PALMITIC ACID, TRIGONAL LATTICE Z
Descriptor:BETA-LACTOGLOBULIN, PALMITIC ACID
Authors:Kontopidis, G., Sawyer, L.
Deposit date:2002-04-01
Release date:2002-06-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:The Ligand-Binding Site of Bovine Beta-Lactoglobulin: Evidence for a Function?
J.Mol.Biol., 318, 2002
1QFE
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THE STRUCTURE OF TYPE I 3-DEHYDROQUINATE DEHYDRATASE FROM SALMONELLA TYPHI
Descriptor:PROTEIN (3-DEHYDROQUINATE DEHYDRATASE), 3-AMINO-4,5-DIHYDROXY-CYCLOHEX-1-ENECARBOXYLATE
Authors:Shrive, A.K., Polikarpov, I., Sawyer, L., Coggins, J.R., Hawkins, A.R.
Deposit date:1999-04-05
Release date:2000-04-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The two types of 3-dehydroquinase have distinct structures but catalyze the same overall reaction.
Nat.Struct.Biol., 6, 1999
1B8E
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HIGH RESOLUTION CRYSTAL STRUCTURE OF THE BOVINE BETA-LACTOGLOBULIN (ISOFORMS A AND B) IN ORTHOROMBIC SPACE GROUP
Descriptor:PROTEIN (BETA-LACTOGLOBULIN)
Authors:Oliveira, K.M.G., Sawyer, L., Polikarpov, I.
Deposit date:1999-01-30
Release date:2001-05-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Crystal structures of bovine beta-lactoglobulin in the orthorhombic space group C222(1). Structural differences between genetic variants A and B and features of the Tanford transition.
Eur.J.Biochem., 268, 2001
1BEB
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BOVINE BETA-LACTOGLOBULIN, LATTICE X
Descriptor:BETA-LACTOGLOBULIN, SULFATE ION
Authors:Brownlow, S., Morais-Cabral, J.H., Sawyer, L.
Deposit date:1996-12-20
Release date:1997-05-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Bovine beta-lactoglobulin at 1.8 A resolution--still an enigmatic lipocalin.
Structure, 5, 1997
1BS0
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PLP-DEPENDENT ACYL-COA SYNTHASE
Descriptor:PROTEIN (8-AMINO-7-OXONANOATE SYNTHASE), SULFATE ION
Authors:Alexeev, D., Alexeeva, M., Baxter, R.L., Campopiano, D.J., Webster, S.P., Sawyer, L.
Deposit date:1998-08-31
Release date:1999-08-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:The crystal structure of 8-amino-7-oxononanoate synthase: a bacterial PLP-dependent, acyl-CoA-condensing enzyme.
J.Mol.Biol., 284, 1998
1DTY
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CRYSTAL STRUCTURE OF ADENOSYLMETHIONINE-8-AMINO-7-OXONANOATE AMINOTRANSFERASE WITH PYRIDOXAL PHOSPHATE COFACTOR.
Descriptor:ADENOSYLMETHIONINE-8-AMINO-7-OXONONANOATE AMINOTRANSFERASE, SODIUM ION, PYRIDOXAL-5'-PHOSPHATE
Authors:Alexeev, D., Sawyer, L., Baxter, R.L., Alexeeva, M.V., Campopiano, D.
Deposit date:2000-01-13
Release date:2000-02-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:Crystal structure of adenosylmethionine-8-amino-7-oxonanoate aminotransferase with pyridoxal phosphate cofactor
to be published
1GQN
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NATIVE 3-DEHYDROQUINASE FROM SALMONELLA TYPHI
Descriptor:3-DEHYDROQUINATE DEHYDRATASE
Authors:Lee, W.-H., Perles, L.A., Nagem, R.A.P., Polikarpov, I., Sawyer, L.
Deposit date:2001-11-26
Release date:2003-11-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Comparison of Different Crystal Forms of 3-Dehydroquinase from Salmonella Typhi and its Implications for Enzyme Activity
Acta Crystallogr.,Sect.D, 58, 2002
1GX8
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BOVINE BETA-LACTOGLOBULIN COMPLEXED WITH RETINOL, TRIGONAL LATTICE Z
Descriptor:BETA-LACTOGLOBULIN, RETINOL
Authors:Kontopidis, G., Sawyer, L.
Deposit date:2002-03-29
Release date:2002-06-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The Ligand-Binding Site of Bovine Beta-Lactoglobulin: Evidence for a Function?
J.Mol.Biol., 318, 2002
1GX9
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BOVINE BETA-LACTOGLOBULIN COMPLEXED WITH RETINOIC ACID, TRIGONAL LATTICE Z
Descriptor:BETA-LACTOGLOBULIN, RETINOIC ACID
Authors:Kontopidis, G., Sawyer, L.
Deposit date:2002-03-29
Release date:2002-06-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.34 Å)
Cite:The Ligand-Binding Site of Bovine Beta-Lactoglobulin: Evidence for a Function?
J.Mol.Biol., 318, 2002
1L9W
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CRYSTAL STRUCTURE OF 3-DEHYDROQUINASE FROM SALMONELLA TYPHI COMPLEXED WITH REACTION PRODUCT
Descriptor:3-dehydroquinate dehydratase aroD, 3-AMINO-4,5-DIHYDROXY-CYCLOHEX-1-ENECARBOXYLATE
Authors:Lee, W.H., Perles, L.A., Nagem, R.A.P., Shrive, A.K., Hawkins, A., Sawyer, L., Polikarpov, I.
Deposit date:2002-03-26
Release date:2003-03-26
Last modified:2012-02-08
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Comparison of different crystal forms of 3-dehydroquinase from Salmonella typhi and its implication for the enzyme activity.
Acta Crystallogr.,Sect.D, 58, 2002
1QG5
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HIGH RESOLUTION CRYSTAL STRUCTURE OF THE BOVINE BETA-LACTOGLOBULIN (ISOFORM A)
Descriptor:BETA-LACTOGLOBULIN
Authors:Oliveira, K.M.G., Sawyer, L., Polikarpov, I.
Deposit date:1999-04-20
Release date:2001-04-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structures of bovine beta-lactoglobulin in the orthorhombic space group C222(1). Structural differences between genetic variants A and B and features of the Tanford transition.
Eur.J.Biochem., 268, 2001
4CK4
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OVINE BETA-LACTOGLOBULIN AT ATOMIC RESOLUTION
Descriptor:BETA_LACTOGLOBULIN-1/B, SULFATE ION, AMMONIUM ION, ...
Authors:Kontopidis, G., Nordle, A., Sawyer, L.
Deposit date:2013-12-27
Release date:2014-10-08
Last modified:2015-05-27
Method:X-RAY DIFFRACTION (1.12 Å)
Cite:Ovine Beta-Lactoglobulin at Atomic Resolution
Acta Crystallogr.,Sect.F, 70, 2014
1UBI
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SYNTHETIC STRUCTURAL AND BIOLOGICAL STUDIES OF THE UBIQUITIN SYSTEM. PART 1
Descriptor:UBIQUITIN
Authors:Alexeev, D., Bury, S.M., Turner, M.A., Ogunjobi, O.M., Muir, T.W., Ramage, R., Sawyer, L.
Deposit date:1994-02-03
Release date:1994-05-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Synthetic, structural and biological studies of the ubiquitin system: the total chemical synthesis of ubiquitin.
Biochem.J., 299, 1994
2DHQ
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3-DEHYDROQUINATE DEHYDRATASE FROM MYCOBACTERIUM TUBERCULOSIS
Descriptor:PROTEIN (3-DEHYDROQUINATE DEHYDRATASE)
Authors:Gourley, D.G., Hawkins, A.R., Coggins, J.R., Isaacs, N.W.
Deposit date:1999-01-29
Release date:1999-05-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:The two types of 3-dehydroquinase have distinct structures but catalyze the same overall reaction.
Nat.Struct.Biol., 6, 1999
2G6W
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SUICIDE INHIBITION OF A-OXAMINE SYNTHASE: STRUCTURES OF THE COVALENT ADDUCTS OF 8-AMINO-7-OXONANOATE SYNTHASE WITH TRIFLUOROALANINE
Descriptor:8-amino-7-oxononanoate synthase, (4-{(E)-[(2,2-DIFLUOROETHYL)IMINO]METHYL}-5-HYDROXY-6-METHYLPYRIDIN-3-YL)METHYL DIHYDROGEN PHOSPHATE
Authors:Alexeev, D.
Deposit date:2006-02-26
Release date:2006-04-25
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:Suicide inhibition of alpha-oxamine synthases: structures of the covalent adducts of 8-amino-7-oxononanoate synthase with trifluoroalanine.
Org.Biomol.Chem., 4, 2006
3EST
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STRUCTURE OF NATIVE PORCINE PANCREATIC ELASTASE AT 1.65 ANGSTROMS RESOLUTION
Descriptor:PORCINE PANCREATIC ELASTASE, CALCIUM ION, SULFATE ION
Authors:Meyer, E.F., Cole, G., Radhakrishnan, R., Epp, O.
Deposit date:1987-09-17
Release date:1988-01-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structure of native porcine pancreatic elastase at 1.65 A resolutions.
Acta Crystallogr.,Sect.B, 44, 1988
6GE7
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THERMODYNAMIC, CRYSTALLOGRAPHIC AND COMPUTATIONAL STUDIES OF NON MAMMALIAN FATTY ACID BINDING TO BOVINE B-LACTOGLOBULIN
Descriptor:Beta-lactoglobulin, nonadecanoic acid
Authors:Kontopidis, G., Rovoli, M.
Deposit date:2018-04-25
Release date:2018-06-20
Last modified:2018-07-11
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Thermodynamic, crystallographic and computational studies of non-mammalian fatty acid binding to bovine beta-Lactoglobulin.
Int. J. Biol. Macromol., 118, 2018
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