Author results

2M5K
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ATOMIC-RESOLUTION STRUCTURE OF A DOUBLET CROSS-BETA AMYLOID FIBRIL
Descriptor:Transthyretin
Authors:Fitzpatrick, A.W.P., Debelouchina, G.T., Bayro, M.J., Clare, D.K., Caporini, M.A., Bajaj, V.S., Jaroniec, C.P., Wang, L., Ladizhansky, V., Muller, S., MacPhee, C.E., Waudby, C.A., Mott, H.R., de Simone, A., Knowles, T.P.J., Saibil, H.R., Vendruscolo, M., Orlova, E.V., Griffin, R.G., Dobson, C.M.
Deposit date:2013-02-27
Release date:2013-12-04
Last modified:2018-07-18
Method:SOLID-STATE NMR (12.7 Å), ELECTRON MICROSCOPY
Cite:Atomic structure and hierarchical assembly of a cross-beta amyloid fibril.
Proc.Natl.Acad.Sci.USA, 110, 2013
2M5M
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ATOMIC-RESOLUTION STRUCTURE OF A TRIPLET CROSS-BETA AMYLOID FIBRIL
Descriptor:Transthyretin
Authors:Fitzpatrick, A.W.P., Debelouchina, G.T., Bayro, M.J., Clare, D.K., Caporini, M.A., Bajaj, V.S., Jaroniec, C.P., Wang, L., Ladizhansky, V., Muller, S., MacPhee, C.E., Waudby, C.A., Mott, H.R., de Simone, A., Knowles, T.P.J., Saibil, H.R., Vendruscolo, M., Orlova, E.V., Griffin, R.G., Dobson, C.M.
Deposit date:2013-02-27
Release date:2013-12-04
Last modified:2018-07-18
Method:SOLID-STATE NMR (12.2 Å), ELECTRON MICROSCOPY
Cite:Atomic structure and hierarchical assembly of a cross-beta amyloid fibril.
Proc.Natl.Acad.Sci.USA, 110, 2013
2M5N
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ATOMIC-RESOLUTION STRUCTURE OF A CROSS-BETA PROTOFILAMENT
Descriptor:Transthyretin
Authors:Fitzpatrick, A.W.P., Debelouchina, G.T., Bayro, M.J., Clare, D.K., Caporini, M.A., Bajaj, V.S., Jaroniec, C.P., Wang, L., Ladizhansky, V., Muller, S., MacPhee, C.E., Waudby, C.A., Mott, H.R., de Simone, A., Knowles, T.P.J., Saibil, H.R., Vendruscolo, M., Orlova, E.V., Griffin, R.G., Dobson, C.M.
Deposit date:2013-02-27
Release date:2013-07-17
Method:SOLID-STATE NMR
Cite:Atomic structure and hierarchical assembly of a cross-{beta} amyloid fibril.
Proc.Natl.Acad.Sci.USA, 110, 2013
3ZPK
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ATOMIC-RESOLUTION STRUCTURE OF A QUADRUPLET CROSS-BETA AMYLOID FIBRIL
Descriptor:TRANSTHYRETIN
Authors:Fitzpatrick, A.w.P., Debelouchina, G.T., Bayro, M.J., Clare, D.K., Caporini, M.A., Bajaj, V.S., Jaroniec, C.P., Wang, L., Ladizhansky, V., Muller, S.A., MacPhee, C.E., Waudby, C.A., Mott, H.R., de Simone, A., Knowles, T.P.J., Saibil, H.R., Vendruscolo, M., Orlova, E.V., Griffin, R.G., Dobson, C.M.
Deposit date:2013-02-28
Release date:2013-12-04
Last modified:2018-03-21
Method:SOLID-STATE NMR, ELECTRON MICROSCOPY
Cite:Atomic Structure and Hierarchical Assembly of a Cross-Beta Amyloid Fibril.
Proc.Natl.Acad.Sci.USA, 110, 2013
4A8D
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DEGP DODECAMER WITH BOUND OMP
Descriptor:PERIPLASMIC SERINE ENDOPROTEASE DEGP, OUTER MEMBRANE PROTEIN C
Authors:Malet, H., Krojer, T., Sawa, J., Schafer, E., Saibil, H.R., Ehrmann, M., Clausen, T.
Deposit date:2011-11-20
Release date:2012-01-11
Last modified:2017-08-30
Method:ELECTRON MICROSCOPY (28 Å)
Cite:Newly Folded Substrates Inside the Molecular Cage of the Htra Chaperone Degq
Nat.Struct.Mol.Biol., 19, 2012
1GR5
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SOLUTION STRUCTURE OF APO GROEL BY CRYO-ELECTRON MICROSCOPY
Descriptor:60 KDA CHAPERONIN
Authors:Ranson, N.A., Farr, G.W., Roseman, A.M., Gowen, B., Fenton, W.A., Horwich, A.L., Saibil, H.R.
Deposit date:2001-12-14
Release date:2002-01-28
Last modified:2019-10-23
Method:ELECTRON MICROSCOPY (7.9 Å)
Cite:ATP-Bound States of Groel Captured by Cryo-Electron Microscopy.
Cell(Cambridge,Mass.), 107, 2001
1GRU
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SOLUTION STRUCTURE OF GROES-ADP7-GROEL-ATP7 COMPLEX BY CRYO-EM
Descriptor:GROEL, GROES
Authors:Ranson, N.A., Farr, G.W., Roseman, A.M., Gowen, B., Fenton, W.A., Horwich, A.L., Saibil, H.R.
Deposit date:2001-12-16
Release date:2002-01-28
Last modified:2019-10-23
Method:ELECTRON MICROSCOPY (12.5 Å)
Cite:ATP-Bound States of Groel Captured by Cryo-Electron Microscopy.
Cell(Cambridge,Mass.), 107, 2001
2BK1
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THE PORE STRUCTURE OF PNEUMOLYSIN, OBTAINED BY FITTING THE ALPHA CARBON TRACE OF PERFRINGOLYSIN O INTO A CRYO-EM MAP
Descriptor:PERFRINGOLYSIN O
Authors:Tilley, S.J., Orlova, E.V., Gilbert, R.J.C., Andrew, P.W., Saibil, H.R.
Deposit date:2005-02-10
Release date:2005-05-04
Last modified:2017-04-19
Method:ELECTRON MICROSCOPY (29 Å)
Cite:Structural Basis of Pore Formation by the Bacterial Toxin Pneumolysin
Cell(Cambridge,Mass.), 121, 2005
2BK2
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THE PREPORE STRUCTURE OF PNEUMOLYSIN, OBTAINED BY FITTING THE ALPHA CARBON TRACE OF PERFRINGOLYSIN O INTO A CRYO-EM MAP
Descriptor:PERFRINGOLYSIN O
Authors:Tilley, S.J., Orlova, E.V., Gilbert, R.J.C., Andrew, P.W., Saibil, H.R.
Deposit date:2005-02-10
Release date:2005-05-04
Last modified:2013-01-16
Method:ELECTRON MICROSCOPY (28 Å)
Cite:Structural Basis of Pore Formation by the Bacterial Toxin Pneumolysin
Cell(Cambridge,Mass.), 121, 2005
2BYU
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NEGATIVE STAIN EM RECONSTRUCTION OF M.TUBERCULOSIS ACR1(HSP 16.3) FITTED WITH WHEAT SHSP DIMER
Descriptor:HEAT SHOCK PROTEIN 16.9B
Authors:Kennaway, C.K., Benesch, J.L.P., Gohlke, U., Wang, L., Robinson, C.V., Orlova, E.V., Saibil, H.R., Keep, N.H.
Deposit date:2005-08-05
Release date:2005-08-22
Last modified:2019-10-23
Method:ELECTRON MICROSCOPY (16.5 Å)
Cite:Dodecameric Structure of the Small Heat Shock Protein Acr1 from Mycobacterium Tuberculosis.
J.Biol.Chem., 280, 2005
2C7C
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FITTED COORDINATES FOR GROEL-ATP7-GROES CRYO-EM COMPLEX (EMD-1180)
Descriptor:60 KDA CHAPERONIN, 10 KDA CHAPERONIN MOLECULE: GROES, PROTEIN CPN10, ...
Authors:Ranson, N.A., Clare, D.K., Farr, G.W., Houldershaw, D., Horwich, A.L., Saibil, H.R.
Deposit date:2005-11-22
Release date:2006-01-25
Last modified:2019-10-23
Method:ELECTRON MICROSCOPY (7.7 Å)
Cite:Allosteric Signalling of ATP Hydrolysis in Groel-Groes Complexes.
Nat.Struct.Mol.Biol., 13, 2006
2C7D
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FITTED COORDINATES FOR GROEL-ADP7-GROES CRYO-EM COMPLEX (EMD-1181)
Descriptor:60 KDA CHAPERONIN, 10 KDA CHAPERONIN MOLECULE: GROES, PROTEIN CPN10, ...
Authors:Ranson, N.A., Clare, D.K., Farr, G.W., Houldershaw, D., Horwich, A.L., Saibil, H.R.
Deposit date:2005-11-22
Release date:2006-01-25
Last modified:2019-10-23
Method:ELECTRON MICROSCOPY (8.7 Å)
Cite:Allosteric Signalling of ATP Hydrolysis in Groel-Groes Complexes.
Nat.Struct.Mol.Biol., 13, 2006
2C7E
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REVISED ATOMIC STRUCTURE FITTING INTO A GROEL(D398A)-ATP7 CRYO-EM MAP (EMD 1047)
Descriptor:60 KDA CHAPERONIN, POTASSIUM ION, MAGNESIUM ION, ...
Authors:Ranson, N.A., Farr, G.W., Roseman, A.M., Gowen, B., Fenton, W.A., Horwich, A.L., Saibil, H.R.
Deposit date:2005-11-22
Release date:2006-02-16
Last modified:2019-10-23
Method:ELECTRON MICROSCOPY (9.7 Å)
Cite:ATP-Bound States of Groel Captured by Cryo-Electron Microscopy
Cell(Cambridge,Mass.), 107, 2001
2CGT
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GROEL-ADP-GP31 COMPLEX
Descriptor:60 KDA GROEL, CAPSID ASSEMBLY PROTEIN GP31
Authors:Clare, D.K., Bakkes, P.J., van Heerikhuizen, H., van der Vies, S.M., Saibil, H.R.
Deposit date:2006-03-09
Release date:2006-03-29
Last modified:2019-10-23
Method:ELECTRON MICROSCOPY (8.2 Å)
Cite:An Expanded Protein Folding Cage in the Groel-Gp31 Complex.
J.Mol.Biol., 358, 2006
2H50
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MULTIPLE DISTINCT ASSEMBLIES REVEAL CONFORMATIONAL FLEXIBILITY IN THE SMALL HEAT SHOCK PROTEIN HSP26
Descriptor:small heat shock protein Hsp26
Authors:White, H.E., Orlova, E.V., Chen, S., Wang, L., Ignatiou, A., Gowen, B., Stromer, T., Franzmann, T.M., Haslbeck, M., Buchner, J., Saibil, H.R.
Deposit date:2006-05-25
Release date:2006-08-01
Last modified:2019-11-06
Method:ELECTRON MICROSCOPY (10.8 Å)
Cite:Multiple distinct assemblies reveal conformational flexibility in the small heat shock protein hsp26
Structure, 14, 2006
2H53
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MULTIPLE DISTINCT ASSEMBLIES REVEAL CONFORMATIONAL FLEXIBILITY IN THE SMALL HEAT SHOCK PROTEIN HSP26
Descriptor:small heat shock protein Hsp26
Authors:White, H.E., Orlova, E.V., Chen, S., Wang, L., Ignatiou, A., Gowen, B., Stromer, T., Franzmann, T.M., Haslbeck, M., Buchner, J., Saibil, H.R.
Deposit date:2006-05-25
Release date:2006-08-01
Last modified:2019-11-06
Method:ELECTRON MICROSCOPY (11.5 Å)
Cite:Multiple distinct assemblies reveal conformational flexibility in the small heat shock protein hsp26
Structure, 14, 2006
2ZLE
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CRYO-EM STRUCTURE OF DEGP12/OMP
Descriptor:Protease do, Outer membrane protein C
Authors:Schaefer, E., Saibil, H.R.
Deposit date:2008-04-09
Release date:2008-06-03
Last modified:2017-02-08
Method:ELECTRON MICROSCOPY (28 Å)
Cite:Structural basis for the regulated protease and chaperone function of DegP
Nature, 453, 2008
3CS0
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CRYSTAL STRUCTURE OF DEGP24
Descriptor:Periplasmic serine endoprotease DegP, pentapeptide
Authors:Krojer, T., Sawa, J., Schaefer, E., Saibil, H.R., Ehrmann, M., Clausen, T.
Deposit date:2008-04-08
Release date:2008-05-27
Last modified:2019-11-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural basis for the regulated protease and chaperone function of DegP
Nature, 453, 2008
4A8A
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ASYMMETRIC CRYO-EM RECONSTRUCTION OF E. COLI DEGQ 12-MER IN COMPLEX WITH LYSOZYME
Descriptor:PERIPLASMIC PH-DEPENDENT SERINE ENDOPROTEASE DEGQ, LYSOZYME C
Authors:Malet, H., Canellas, F., Sawa, J., Yan, J., Thalassinos, K., Ehrmann, M., Clausen, T., Saibil, H.R.
Deposit date:2011-11-20
Release date:2011-12-28
Last modified:2017-08-23
Method:ELECTRON MICROSCOPY (14.2 Å)
Cite:Newly Folded Substrates Inside the Molecular Cage of the Htra Chaperone Degq
Nat.Struct.Mol.Biol., 19, 2012
4A8B
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SYMMETRIZED CRYO-EM RECONSTRUCTION OF E. COLI DEGQ 12-MER IN COMPLEX WITH LYSOZYMES
Descriptor:PERIPLASMIC PH-DEPENDENT SERINE ENDOPROTEASE DEGQ, LYSOZYME C
Authors:Malet, H., Canellas, F., Sawa, J., Yan, J., Thalassinos, K., Ehrmann, M., Clausen, T., Saibil, H.R.
Deposit date:2011-11-20
Release date:2012-01-11
Last modified:2017-08-23
Method:ELECTRON MICROSCOPY (13 Å)
Cite:Newly Folded Substrates Inside the Molecular Cage of the Htra Chaperone Degq
Nat.Struct.Mol.Biol., 19, 2012
4A8C
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SYMMETRIZED CRYO-EM RECONSTRUCTION OF E. COLI DEGQ 12-MER IN COMPLEX WITH A BINDING PEPTIDE
Descriptor:PERIPLASMIC PH-DEPENDENT SERINE ENDOPROTEASE DEGQ
Authors:Malet, H., Canellas, F., Sawa, J., Yan, J., Thalassinos, K., Ehrmann, M., Clausen, T., Saibil, H.R.
Deposit date:2011-11-20
Release date:2012-01-11
Last modified:2017-08-30
Method:ELECTRON MICROSCOPY (7.5 Å)
Cite:Newly Folded Substrates Inside the Molecular Cage of the Htra Chaperone Degq
Nat.Struct.Mol.Biol., 19, 2012
4A9G
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SYMMETRIZED CRYO-EM RECONSTRUCTION OF E. COLI DEGQ 24-MER IN COMPLEX WITH BETA-CASEIN
Descriptor:PERIPLASMIC PH-DEPENDENT SERINE ENDOPROTEASE DEGQ
Authors:Malet, H., Canellas, F., Sawa, J., Yan, J., Thalassinos, K., Ehrmann, M., Clausen, T., Saibil, H.R.
Deposit date:2011-11-26
Release date:2012-01-11
Last modified:2017-08-23
Method:ELECTRON MICROSCOPY (7.5 Å)
Cite:Newly Folded Substrates Inside the Molecular Cage of the Htra Chaperone Degq
Nat.Struct.Mol.Biol., 19, 2012
4AAQ
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ATP-TRIGGERED MOLECULAR MECHANICS OF THE CHAPERONIN GROEL
Descriptor:60 KDA CHAPERONIN, ADENOSINE-5'-TRIPHOSPHATE, PHOSPHATE ION, ...
Authors:Clare, D.K., Vasishtan, D., Stagg, S., Quispe, J., Farr, G.W., Topf, M., Horwich, A.L., Saibil, H.R.
Deposit date:2011-12-05
Release date:2012-12-12
Last modified:2017-08-30
Method:ELECTRON MICROSCOPY (8 Å)
Cite:ATP-Triggered Conformational Changes Delineate Substrate-Binding and -Folding Mechanics of the Groel Chaperonin.
Cell(Cambridge,Mass.), 149, 2012
4AAR
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ATP-TRIGGERED MOLECULAR MECHANICS OF THE CHAPERONIN GROEL
Descriptor:60 KDA CHAPERONIN, ADENOSINE-5'-TRIPHOSPHATE, PHOSPHATE ION, ...
Authors:Clare, D.K., Vasishtan, D., Stagg, S., Quispe, J., Farr, G.W., Topf, M., Horwich, A.L., Saibil, H.R.
Deposit date:2011-12-05
Release date:2012-12-12
Last modified:2017-08-23
Method:ELECTRON MICROSCOPY (8 Å)
Cite:ATP-Triggered Conformational Changes Delineate Substrate-Binding and -Folding Mechanics of the Groel Chaperonin.
Cell(Cambridge,Mass.), 149, 2012
4AAS
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ATP-TRIGGERED MOLECULAR MECHANICS OF THE CHAPERONIN GROEL
Descriptor:60 KDA CHAPERONIN, PHOSPHATE ION, MAGNESIUM ION, ...
Authors:Clare, D.K., Vasishtan, D., Stagg, S., Quispe, J., Farr, G.W., Topf, M., Horwich, A.L., Saibil, H.R.
Deposit date:2011-12-05
Release date:2012-12-12
Last modified:2017-08-23
Method:ELECTRON MICROSCOPY (8.5 Å)
Cite:ATP-Triggered Conformational Changes Delineate Substrate-Binding and -Folding Mechanics of the Groel Chaperonin.
Cell(Cambridge,Mass.), 149, 2012
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