Author results

3LQ6
  • Download 3lq6
  • View 3lq6
Molmil generated image of 3lq6
CRYSTAL STRUCTURE OF MURINE NOROVIRUS PROTRUDING (P) DOMAIN
Descriptor:Capsid protein
Authors:Rubin, J.R., Stuckey, J.A.
Deposit date:2010-02-08
Release date:2010-04-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:High-resolution x-ray structure and functional analysis of the murine norovirus 1 capsid protein protruding domain.
J.Virol., 84, 2010
3LQE
  • Download 3lqe
  • View 3lqe
Molmil generated image of 3lqe
X-RAY STRUCTURE OF THE MURINE NOROVIRUS (MNV)-1 CAPSID PROTEIN PROTRUDING (P) DOMAIN
Descriptor:Capsid protein
Authors:Rubin, J.R., Stuckey, J.A.
Deposit date:2010-02-09
Release date:2010-04-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:High-resolution x-ray structure and functional analysis of the murine norovirus 1 capsid protein protruding domain.
J.Virol., 84, 2010
2RIG
  • Download 2rig
  • View 2rig
Molmil generated image of 2rig
CRYSTAL STRUCTURE OF RECOMBINANT RABBIT INTERFERON-GAMMA AT 2.7-ANGSTROMS RESOLUTION
Descriptor:INTERFERON-GAMMA
Authors:Samudzi, C.T., Burton, L.E., Rubin, J.R.
Deposit date:1993-01-11
Release date:1993-01-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of recombinant rabbit interferon-gamma at 2.7-A resolution.
J.Biol.Chem., 266, 1991
1BKL
  • Download 1bkl
  • View 1bkl
Molmil generated image of 1bkl
SELF-ASSOCIATED APO SRC SH2 DOMAIN
Descriptor:PP60 V-SRC TYROSINE KINASE TRANSFORMING PROTEIN
Authors:Holland, D.R., Rubin, J.R.
Deposit date:1997-05-02
Release date:1997-07-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Novel Pp60Src Sh2 Domain Crystal Structures: A 2.0 Angstrom Co-Crystal Structure of a D-Amino Acid Substituted Phosphopeptide Complex and a 2.1 Angstrom Apo Structure Displaying Self-Association
To be Published
1BKM
  • Download 1bkm
  • View 1bkm
Molmil generated image of 1bkm
COCRYSTAL STRUCTURE OF D-AMINO ACID SUBSTITUTED PHOSPHOPEPTIDE COMPLEX
Descriptor:PP60 V-SRC TYROSINE KINASE TRANSFORMING PROTEIN, [[O-PHOSPHONO-N-ACETYL-TYROSINYL]-GLUTAMYL-3[CYCLOHEXYLMETHYL]ALANINYL]-AMINE
Authors:Holland, D.R., Rubin, J.R.
Deposit date:1997-05-02
Release date:1997-07-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure-Based Design of a Novel Series of Nonpeptide Ligands that Bind to the Pp60Src Sh2 Domain
J.Am.Chem.Soc., 119, 1997
1JWT
  • Download 1jwt
  • View 1jwt
Molmil generated image of 1jwt
CRYSTAL STRUCTURE OF THROMBIN IN COMPLEX WITH A NOVEL BICYCLIC LACTAM INHIBITOR
Descriptor:Prothrombin, 4-OXO-2-PHENYLMETHANESULFONYL-OCTAHYDRO-PYRROLO[1,2-A]PYRAZINE-6-CARBOXYLIC ACID [1-(N-HYDROXYCARBAMIMIDOYL)-PIPERIDIN-4-YLMETHYL]-AMIDE
Authors:Levesque, S., St-Denis, Y., Bachand, B., Preville, P., Leblond, L., Winocour, P.D., Edmunds, J.J., Rubin, J.R., Siddiqui, M.A.
Deposit date:2001-09-05
Release date:2002-02-27
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Novel bicyclic lactam inhibitors of thrombin: potency and selectivity optimization through P1 residues.
Bioorg.Med.Chem.Lett., 11, 2001
1QIB
  • Download 1qib
  • View 1qib
Molmil generated image of 1qib
CRYSTAL STRUCTURE OF GELATINASE A CATALYTIC DOMAIN
Descriptor:72 kDa type IV collagenase, ZINC ION, CALCIUM ION
Authors:Dhanaraj, V., Williams, M.G., Ye, Q.-Z., Molina, F., Johnson, L.L., Ortwine, D.F., Pavlovsky, A., Rubin, J.R., Skeean, R.W., White, A.D., Humblet, C., Hupe, D.J., Blundell, T.L.
Deposit date:1999-06-11
Release date:1999-11-19
Last modified:2017-05-31
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:X-ray structure of gelatinase A catalytic domain complexed with a hydroxamate inhibitor
Croatica Chemica Acta, 72, 1999
1RFB
  • Download 1rfb
  • View 1rfb
Molmil generated image of 1rfb
CRYSTAL STRUCTURE OF RECOMBINANT BOVINE INTERFERON-GAMMA AT 3.0 ANGSTROMS RESOLUTION
Descriptor:INTERFERON-GAMMA
Authors:Samudzi, C.T., Rubin, J.R.
Deposit date:1993-06-30
Release date:1994-01-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure of recombinant bovine interferon-gamma at 3.0 A resolution.
Acta Crystallogr.,Sect.D, 49, 1993
2ABJ
  • Download 2abj
  • View 2abj
Molmil generated image of 2abj
CRYSTAL STRUCTURE OF HUMAN BRANCHED CHAIN AMINO ACID TRANSAMINASE IN A COMPLEX WITH AN INHIBITOR, C16H10N2O4F3SCL, AND PYRIDOXAL 5' PHOSPHATE.
Descriptor:Branched-chain-amino-acid aminotransferase, cytosolic, N'-(5-CHLOROBENZOFURAN-2-CARBONYL)-2-(TRIFLUOROMETHYL)BENZENESULFONOHYDRAZIDE, ...
Authors:Ohren, J.F., Moreland, D.W., Rubin, J.R., Hu, H.L., McConnell, P.C., Mistry, A., Mueller, W.T., Scholten, J.D., Hasemann, C.H.
Deposit date:2005-07-15
Release date:2006-06-27
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The design and synthesis of human branched-chain amino acid aminotransferase inhibitors for treatment of neurodegenerative diseases.
Bioorg.Med.Chem.Lett., 16, 2006
2R8E
  • Download 2r8e
  • View 2r8e
Molmil generated image of 2r8e
CRYSTAL STRUCTURE OF YRBI FROM ESCHERICHIA COLI IN COMPLEX WITH MG
Descriptor:3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, MAGNESIUM ION, CHLORIDE ION
Authors:Tsodikov, O.V., Aggarwal, P., Rubin, J.R., Stuckey, J.A., Woodard, R., Biswas, T.
Deposit date:2007-09-10
Release date:2008-09-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:The Tail of KdsC: CONFORMATIONAL CHANGES CONTROL THE ACTIVITY OF A HALOACID DEHALOGENASE SUPERFAMILY PHOSPHATASE.
J.Biol.Chem., 284, 2009
2R8X
  • Download 2r8x
  • View 2r8x
Molmil generated image of 2r8x
CRYSTAL STRUCTURE OF YRBI PHOSPHATASE FROM ESCHERICHIA COLI
Descriptor:3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, CHLORIDE ION
Authors:Tsodikov, O.V., Aggarwal, P., Rubin, J.R., Stuckey, J.A., Woodard, R.W., Biswas, T.
Deposit date:2007-09-11
Release date:2008-09-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The Tail of KdsC: CONFORMATIONAL CHANGES CONTROL THE ACTIVITY OF A HALOACID DEHALOGENASE SUPERFAMILY PHOSPHATASE.
J.Biol.Chem., 284, 2009
2R8Y
  • Download 2r8y
  • View 2r8y
Molmil generated image of 2r8y
CRYSTAL STRUCTURE OF YRBI PHOSPHATASE FROM ESCHERICHIA COLI IN A COMPLEX WITH CA
Descriptor:YrbI from Escherichia coli, CALCIUM ION, CHLORIDE ION
Authors:Tsodikov, O.V., Aggarwal, P., Rubin, J.R., Stuckey, J.A., Woodard, R.W., Biswas, T.
Deposit date:2007-09-11
Release date:2008-09-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:The Tail of KdsC: CONFORMATIONAL CHANGES CONTROL THE ACTIVITY OF A HALOACID DEHALOGENASE SUPERFAMILY PHOSPHATASE.
J.Biol.Chem., 284, 2009
2R8Z
  • Download 2r8z
  • View 2r8z
Molmil generated image of 2r8z
CRYSTAL STRUCTURE OF YRBI PHOSPHATASE FROM ESCHERICHIA COLI IN COMPLEX WITH A PHOSPHATE AND A CALCIUM ION
Descriptor:3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, CALCIUM ION, PHOSPHATE ION
Authors:Tsodikov, O.V., Aggarwal, P., Rubin, J.R., Stuckey, J.A., Woodard, R.W., Biswas, T.
Deposit date:2007-09-11
Release date:2008-09-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The Tail of KdsC: CONFORMATIONAL CHANGES CONTROL THE ACTIVITY OF A HALOACID DEHALOGENASE SUPERFAMILY PHOSPHATASE.
J.Biol.Chem., 284, 2009
1ETU
  • Download 1etu
  • View 1etu
Molmil generated image of 1etu
STRUCTURAL DETAILS OF THE BINDING OF GUANOSINE DIPHOSPHATE TO ELONGATION FACTOR TU FROM E. COLI AS STUDIED BY X-RAY CRYSTALLOGRAPHY
Descriptor:ELONGATION FACTOR TU, MAGNESIUM ION, GUANOSINE-5'-DIPHOSPHATE
Authors:Clark, B.F.C., Lacour, T.F.M., Kjeldgaard, M., Morikawa, K., Nyborg, J., Rubin, R., Thirup, S.
Deposit date:1988-01-15
Release date:1988-07-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural details of the binding of guanosine diphosphate to elongation factor Tu from E. coli as studied by X-ray crystallography.
EMBO J., 4, 1985
1QIA
  • Download 1qia
  • View 1qia
Molmil generated image of 1qia
CRYSTAL STRUCTURE OF STROMELYSIN CATALYTIC DOMAIN
Descriptor:STROMELYSIN-1, ZINC ION, CALCIUM ION
Authors:Williams, M.G., Ye, Q.-Z., Molina, F., Johnson, L.L., Ortwine, D.F., Pavlovsky, A.G., Rubin, J.R., Skeean, R.W., White, A.D., Blundell, T.L., Humblet, C., Hupe, D.J., Dhanaraj, V.
Deposit date:1999-06-11
Release date:2003-02-11
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:X-ray structure of human stromelysin catalytic domain complexed with nonpeptide inhibitors: implications for inhibitor selectivity
Protein Sci., 8, 1999
1QIC
  • Download 1qic
  • View 1qic
Molmil generated image of 1qic
CRYSTAL STRUCTURE OF STROMELYSIN CATALYTIC DOMAIN
Descriptor:PROTEIN (STROMELYSIN-1), ZINC ION, CALCIUM ION
Authors:Williams, M.G., Ye, Q.-Z., Molina, F., Johnson, L.L., Ortwine, D.F., Pavlovsky, A.G., Rubin, J.R., Skeean, R.W., White, A.D., Blundell, T.L., Humblet, C., Hupe, D.J., Dhanaraj, V.
Deposit date:1999-06-11
Release date:2003-02-11
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:X-ray structure of human stromelysin catalytic domain complexed with nonpeptide inhibitors: implications for inhibitor selectivity
Protein Sci., 8, 1999
1SKJ
  • Download 1skj
  • View 1skj
Molmil generated image of 1skj
COCRYSTAL STRUCTURE OF UREA-SUBSTITUTED PHOSPHOPEPTIDE COMPLEX
Descriptor:PP60 V-SRC TYROSINE KINASE TRANSFORMING PROTEIN, 4-[3-CARBOXYMETHYL-3-(4-PHOSPHONOOXY-BENZYL)-UREIDO]-4-[(3-CYCLOHEXYL-PROPYL)-METHYL-CARBAMOYL]BUTYRIC ACID
Authors:Holland, D.R., Rubin, J.R.
Deposit date:1997-09-18
Release date:1998-02-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Design, synthesis, and cocrystal structure of a nonpeptide Src SH2 domain ligand.
J.Med.Chem., 40, 1997
3HYC
  • Download 3hyc
  • View 3hyc
Molmil generated image of 3hyc
CRYSTAL STRUCTURE OF E. COLI PHOSPHATASE YRBI, WITH MG, TETRAGONAL FORM
Descriptor:3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, MAGNESIUM ION, CHLORIDE ION
Authors:Tsodikov, O.V., Biswas, T.
Deposit date:2009-06-22
Release date:2009-09-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.06 Å)
Cite:The Tail of KdsC: CONFORMATIONAL CHANGES CONTROL THE ACTIVITY OF A HALOACID DEHALOGENASE SUPERFAMILY PHOSPHATASE.
J.Biol.Chem., 284, 2009
3I6B
  • Download 3i6b
  • View 3i6b
Molmil generated image of 3i6b
CRYSTAL STRUCTURE OF YRBI LACKING THE LAST 8 RESIDUES, IN COMPLEX WITH KDO AND INORGANIC PHOSPHATE
Descriptor:3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, MAGNESIUM ION, PHOSPHATE ION, ...
Authors:Biswas, T., Tsodikov, O.V.
Deposit date:2009-07-06
Release date:2009-09-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:The Tail of KdsC: CONFORMATIONAL CHANGES CONTROL THE ACTIVITY OF A HALOACID DEHALOGENASE SUPERFAMILY PHOSPHATASE.
J.Biol.Chem., 284, 2009
1TYA
  • Download 1tya
  • View 1tya
Molmil generated image of 1tya
STRUCTURAL ANALYSIS OF A SERIES OF MUTANTS OF TYROSYL-TRNA SYNTHETASE: ENHANCEMENT OF CATALYSIS BY HYDROPHOBIC INTERACTIONS
Descriptor:TYROSYL-tRNA SYNTHETASE, TYROSINE
Authors:Brown, K.A., De Meester, P., Blow, D.M.
Deposit date:1992-07-06
Release date:1994-01-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural Analysis of a Series of Mutants of Tyrosyl-tRNA Synthetase: Enhancement of Catalysis by Hydrophobic Interactions
To be Published
1TYB
  • Download 1tyb
  • View 1tyb
Molmil generated image of 1tyb
STRUCTURAL ANALYSIS OF A SERIES OF MUTANTS OF TYROSYL-TRNA SYNTHETASE: ENHANCEMENT OF CATALYSIS BY HYDROPHOBIC INTERACTIONS
Descriptor:TYROSYL-tRNA SYNTHETASE, TYROSINE
Authors:Brown, K.A., De Meester, P., Blow, D.M.
Deposit date:1992-07-06
Release date:1994-01-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Analysis of a Series of Mutants of Tyrosyl-tRNA Synthetase: Enhancement of Catalysis by Hydrophobic Interactions
To be Published
1TYC
  • Download 1tyc
  • View 1tyc
Molmil generated image of 1tyc
STRUCTURAL ANALYSIS OF A SERIES OF MUTANTS OF TYROSYL-TRNA SYNTHETASE: ENHANCEMENT OF CATALYSIS BY HYDROPHOBIC INTERACTIONS
Descriptor:TYROSYL-tRNA SYNTHETASE
Authors:Brown, K.A., Brick, P., De Meester, P., Blow, D.M.
Deposit date:1992-07-06
Release date:1994-01-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Analysis of a Series of Mutants of Tyrosyl-tRNA Synthetase: Enhancement of Catalysis by Hydrophobic Interactions
To be Published
1TYD
  • Download 1tyd
  • View 1tyd
Molmil generated image of 1tyd
STRUCTURE OF TYROSYL-TRNA SYNTHETASE REFINED AT 2.3 ANGSTROMS RESOLUTION. INTERACTION OF THE ENZYME WITH THE TYROSYL ADENYLATE INTERMEDIATE
Descriptor:TYROSYL-tRNA SYNTHETASE, TYROSINE
Authors:Brown, K.A., De Meester, P., Blow, D.M.
Deposit date:1992-07-06
Release date:1994-01-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of tyrosyl-tRNA synthetase refined at 2.3 A resolution. Interaction of the enzyme with the tyrosyl adenylate intermediate.
J.Mol.Biol., 208, 1989
2TS1
  • Download 2ts1
  • View 2ts1
Molmil generated image of 2ts1
STRUCTURE OF TYROSYL-T/RNA SYNTHETASE REFINED AT 2.3 ANGSTROMS RESOLUTION. INTERACTION OF THE ENZYME WITH THE TYROSYL ADENYLATE INTERMEDIATE
Descriptor:TYROSYL-TRNA SYNTHETASE
Authors:Brick, P., Bhat, T.N., Blow, D.M.
Deposit date:1989-06-29
Release date:1989-10-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of tyrosyl-tRNA synthetase refined at 2.3 A resolution. Interaction of the enzyme with the tyrosyl adenylate intermediate.
J.Mol.Biol., 208, 1989
3TS1
  • Download 3ts1
  • View 3ts1
Molmil generated image of 3ts1
STRUCTURE OF TYROSYL-T/RNA SYNTHETASE REFINED AT 2.3 ANGSTROMS RESOLUTION. INTERACTION OF THE ENZYME WITH THE TYROSYL ADENYLATE INTERMEDIATE
Descriptor:TYROSYL-TRNA SYNTHETASE, PHOSPHORIC ACID 2-AMINO-3-(4-HYDROXY-PHENYL)-PROPYL ESTER ADENOSIN-5'YL ESTER
Authors:Monteilhet, C., Brick, P., Blow, D.M.
Deposit date:1989-06-29
Release date:1989-10-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure of tyrosyl-tRNA synthetase refined at 2.3 A resolution. Interaction of the enzyme with the tyrosyl adenylate intermediate.
J.Mol.Biol., 208, 1989
<12>