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5YAK
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BU of 5yak by Molmil
The crystal structure of human IYD Thr239 mutant with ligand 3-Fluorotyrosine (F-Tyr)
Descriptor: 3-FLUOROTYROSINE, FLAVIN MONONUCLEOTIDE, Iodotyrosine deiodinase 1
Authors:Hu, J.M, Rokita, S.E, Schlessman, J.
Deposit date:2017-09-01
Release date:2018-08-08
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Redox control of iodotyrosine deiodinase
Protein Sci., 28, 2019
6TYK
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BU of 6tyk by Molmil
Crystal structure of iodotyrosine deiodinase (IYD) in the semiquinone form bound to FMN and 3-iodo-L-tyrosine
Descriptor: 3-IODO-TYROSINE, CHLORIDE ION, FLAVIN MONONUCLEOTIDE, ...
Authors:Sun, Z, Kavran, J.M, Rokita, S.E.
Deposit date:2019-08-09
Release date:2021-04-07
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Structure of Tn IYD bound in the semiquinone form bound to FMN and 3-iodo-L-tyrosine
To Be Published
6Q1L
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BU of 6q1l by Molmil
Crystal structure of oxidized iodotyrosine deiodinase (IYD) bound to FMN and 3-iodo-L-tyrosine
Descriptor: 3-IODO-TYROSINE, CHLORIDE ION, FLAVIN MONONUCLEOTIDE, ...
Authors:Sun, Z, Kavran, J.M, Rokita, S.E.
Deposit date:2019-08-05
Release date:2021-04-07
Last modified:2022-04-20
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:The minimal structure for iodotyrosine deiodinase function is defined by an outlier protein from the thermophilic bacterium Thermotoga neapolitana.
J.Biol.Chem., 297, 2021
3TNZ
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BU of 3tnz by Molmil
Crystal structure of Mus musculus iodotyrosine deiodinase (IYD) C217A, C239A bound to FMN and mono-iodotyrosine (MIT)
Descriptor: 3-IODO-TYROSINE, CITRATE ANION, FLAVIN MONONUCLEOTIDE, ...
Authors:Buss, J.M, McTamney, P.M, Rokita, S.E.
Deposit date:2011-09-02
Release date:2012-02-29
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Expression of a soluble form of iodotyrosine deiodinase for active site characterization by engineering the native membrane protein from Mus musculus.
Protein Sci., 21, 2012
3TO0
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BU of 3to0 by Molmil
Crystal structure of Mus musculus iodotyrosine deiodinase (IYD) C217A, C239A bound to FMN
Descriptor: ACETATE ION, FLAVIN MONONUCLEOTIDE, Iodotyrosine deiodinase 1, ...
Authors:Buss, J.M, McTamney, P.M, Rokita, S.E.
Deposit date:2011-09-02
Release date:2012-02-29
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.655 Å)
Cite:Expression of a soluble form of iodotyrosine deiodinase for active site characterization by engineering the native membrane protein from Mus musculus.
Protein Sci., 21, 2012
6Q1B
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BU of 6q1b by Molmil
Crystal structure of oxidized iodotyrosine deiodinase (IYD) bound to FMN and 3-fluoro-L-tyrosine
Descriptor: 3-FLUOROTYROSINE, CHLORIDE ION, FLAVIN MONONUCLEOTIDE, ...
Authors:Sun, Z, Kavran, J.M, Rokita, S.E.
Deposit date:2019-08-03
Release date:2021-02-03
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.596 Å)
Cite:Crystal structure of oxidized Tn IYD bound to FMN and 3-fluoro-L-tyrosine
To Be Published
6PZ0
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BU of 6pz0 by Molmil
Crystal structure of oxidized iodotyrosine deiodinase (IYD) bound to FMN and L-Tyrosine
Descriptor: CHLORIDE ION, FLAVIN MONONUCLEOTIDE, TYROSINE, ...
Authors:Sun, Z, Kavran, J.M, Rokita, S.E.
Deposit date:2019-07-31
Release date:2021-02-03
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The minimal structure for iodotyrosine deiodinase function is defined by an outlier protein from the thermophilic bacterium Thermotoga neapolitana.
J.Biol.Chem., 297, 2021
5KO8
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BU of 5ko8 by Molmil
Crystal structure of haliscomenobacter hydrossis iodotyrosine deiodinase (IYD) bound to FMN and mono-iodotyrosine (I-Tyr)
Descriptor: 3-IODO-TYROSINE, FLAVIN MONONUCLEOTIDE, Nitroreductase
Authors:Ingavat, N, Kavran, J.M, Sun, Z, Rokita, S.E.
Deposit date:2016-06-29
Release date:2017-02-15
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Active Site Binding Is Not Sufficient for Reductive Deiodination by Iodotyrosine Deiodinase.
Biochemistry, 56, 2017
3GH8
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BU of 3gh8 by Molmil
Crystal structure of Mus musculus iodotyrosine deiodinase (IYD) bound to FMN and di-iodotyrosine (DIT)
Descriptor: 3,5-DIIODOTYROSINE, FLAVIN MONONUCLEOTIDE, Iodotyrosine dehalogenase 1, ...
Authors:Thomas, S.R, McTamney, P.M, Adler, J.M, LaRonde-LeBlanc, N, Rokita, S.E.
Deposit date:2009-03-03
Release date:2009-05-12
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.61 Å)
Cite:Crystal structure of iodotyrosine deiodinase, a novel flavoprotein responsible for iodide salvage in thyroid glands.
J.Biol.Chem., 284, 2009
3GB5
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BU of 3gb5 by Molmil
Crystal structure of Mus musculus iodotyrosine deiodinase (IYD) bound to FMN
Descriptor: ACETATE ION, FLAVIN MONONUCLEOTIDE, Iodotyrosine dehalogenase 1, ...
Authors:Thomas, S.R, McTamney, P.M, Adler, J.M, LaRonde-LeBlanc, N, Rokita, S.E.
Deposit date:2009-02-18
Release date:2009-05-12
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of iodotyrosine deiodinase, a novel flavoprotein responsible for iodide salvage in thyroid glands.
J.Biol.Chem., 284, 2009
3GFD
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BU of 3gfd by Molmil
Crystal structure of Mus musculus iodotyrosine deiodinase (IYD) bound to FMN and mono-iodotyrosine (MIT)
Descriptor: 3-IODO-TYROSINE, FLAVIN MONONUCLEOTIDE, GLYCEROL, ...
Authors:Thomas, S.R, McTamney, P.M, Adler, J.M, LaRonde-LeBlanc, N, Rokita, S.E.
Deposit date:2009-02-26
Release date:2009-05-12
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Crystal structure of iodotyrosine deiodinase, a novel flavoprotein responsible for iodide salvage in thyroid glands.
J.Biol.Chem., 284, 2009
5KRD
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BU of 5krd by Molmil
Crystal structure of haliscomenobacter hydrossis iodotyrosine deiodinase (IYD) bound to FMN and 2-iodophenol (2IP)
Descriptor: 2-iodanylphenol, FLAVIN MONONUCLEOTIDE, Nitroreductase
Authors:Ingavat, N, Kavran, J.M, Sun, Z, Rokita, S.
Deposit date:2016-07-07
Release date:2017-02-15
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.103 Å)
Cite:Active Site Binding Is Not Sufficient for Reductive Deiodination by Iodotyrosine Deiodinase.
Biochemistry, 56, 2017
5KO7
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BU of 5ko7 by Molmil
Crystal structure of haliscomenobacter hydrossis iodotyrosine deiodinase (IYD) bound to FMN
Descriptor: FLAVIN MONONUCLEOTIDE, Nitroreductase
Authors:Ingavat, N, Kavran, J.M, Sun, Z, Rokita, S.
Deposit date:2016-06-29
Release date:2017-02-15
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.248 Å)
Cite:Active Site Binding Is Not Sufficient for Reductive Deiodination by Iodotyrosine Deiodinase.
Biochemistry, 56, 2017
4TTB
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BU of 4ttb by Molmil
Crystal structure of homo sapiens IODOTYROSINE DEIODINASE (IYD) bound to FMN
Descriptor: FLAVIN MONONUCLEOTIDE, Iodotyrosine dehalogenase 1
Authors:Chuenchor, W, Hu, J, Rokita, S.
Deposit date:2014-06-20
Release date:2014-11-26
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.447 Å)
Cite:A Switch between One- and Two-electron Chemistry of the Human Flavoprotein Iodotyrosine Deiodinase Is Controlled by Substrate.
J.Biol.Chem., 290, 2015
4TTC
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BU of 4ttc by Molmil
Crystal structure of homo sapiens IODOTYROSINE DEIODINASE bound to FMN and mono-iodotyrosine (MIT)
Descriptor: 3-IODO-TYROSINE, FLAVIN MONONUCLEOTIDE, Iodotyrosine dehalogenase 1
Authors:Chuenchor, W, Hu, J, Rokita, S.
Deposit date:2014-06-20
Release date:2014-11-26
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:A Switch between One- and Two-electron Chemistry of the Human Flavoprotein Iodotyrosine Deiodinase Is Controlled by Substrate.
J.Biol.Chem., 290, 2015

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