Author results

6NXD
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TYPE I L-ASPARAGINASE FROM ESCHERICHIA COLI IN COMPLEX WITH CITRATE AT PH 4
Descriptor:L-asparaginase 1, CHLORIDE ION, CITRIC ACID, ...
Authors:Lubkowski, J., Wlodawer, A.
Deposit date:2019-02-08
Release date:2019-08-07
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Opportunistic complexes of E. coli L-asparaginases with citrate anions
Sci Rep, 9, 2019
6NXC
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ECAI(T162A) MUTANT IN COMPLEX WITH CITRATE AT PH 4
Descriptor:L-asparaginase 1, CITRIC ACID, 1,2-ETHANEDIOL, ...
Authors:Lubkowski, J., Wlodawer, A.
Deposit date:2019-02-08
Release date:2019-08-07
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:Opportunistic complexes of E. coli L-asparaginases with citrate anions
Sci Rep, 9, 2019
6NXB
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ECAII IN COMPLEX WITH CITRATE AT PH 7
Descriptor:L-asparaginase 2, CITRIC ACID, GLYCEROL
Authors:Lubkowski, J., Wlodawer, A.
Deposit date:2019-02-08
Release date:2019-08-07
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Opportunistic complexes of E. coli L-asparaginases with citrate anions
Sci Rep, 9, 2019
6NXA
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ECAII(T89V,K162T) MUTANT IN COMPLEX WITH CITRATE AT PH 7
Descriptor:L-asparaginase 2, ACETIC ACID, GLYCEROL
Authors:Lubkowski, J., Wlodawer, A.
Deposit date:2019-02-08
Release date:2019-08-07
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Opportunistic complexes of E. coli L-asparaginases with citrate anions
Sci Rep, 9, 2019
6NX9
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ECAII(T89V,K162T) MUTANT IN COMPLEX WITH CITRATE AT PH 7
Descriptor:L-asparaginase 2, ACETIC ACID, IMIDAZOLE, ...
Authors:Lubkowski, J., Wlodawer, A.
Deposit date:2019-02-08
Release date:2019-08-07
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Opportunistic complexes of E. coli L-asparaginases with citrate anions
Sci Rep, 9, 2019
6NX8
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ECAII(T89V,K162T) MUTANT IN COMPLEX WITH CITRATE AT PH 6.2
Descriptor:L-asparaginase 2, ACETIC ACID, CITRIC ACID
Authors:Lubkowski, J., Wlodawer, A.
Deposit date:2019-02-08
Release date:2019-08-07
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Opportunistic complexes of E. coli L-asparaginases with citrate anions
Sci Rep, 9, 2019
6NX7
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ECAII(T89V,K162T) MUTANT IN COMPLEX WITH CITRATE AT PH 5.6
Descriptor:L-asparaginase 2, ACETIC ACID, CITRIC ACID
Authors:Lubkowski, J., Wlodawer, A.
Deposit date:2019-02-08
Release date:2019-08-07
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Opportunistic complexes of E. coli L-asparaginases with citrate anions
Sci Rep, 9, 2019
6NX6
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ECAII(T89V,K162T) MUTANT IN COMPLEX WITH CITRATE AT PH 5
Descriptor:L-asparaginase 2, ACETIC ACID, CITRIC ACID
Authors:Lubkowski, J., Wlodawer, A.
Deposit date:2019-02-08
Release date:2019-08-07
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Opportunistic complexes of E. coli L-asparaginases with citrate anions
Sci Rep, 9, 2019
6NR1
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THE X-RAY CRYSTAL STRUCTURE OF STREPTOCOCCUS PNEUMONIAE FATTY ACID KINASE (FAK) B2 PROTEIN LOADED WITH VACCENIC ACID (C18:1 DELTA11) TO 2.1 ANGSTROM RESOLUTION
Descriptor:Fatty Acid Kinase (Fak) B2 protein (SPR1019), VACCENIC ACID, GLYCEROL
Authors:Cuypers, M.G., Gullett, J.M., Subramanian, C., White, S.W., Rock, C.O.
Deposit date:2019-01-22
Release date:2019-08-21
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The X-ray crystal structure of Streptococcus pneumoniae Fatty Acid Kinase (Fak) B2 protein loaded with Vaccenic acid (C18:1 delta11) to 2.1 Angstrom resolution
To Be Published
6NOK
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THE X-RAY CRYSTAL STRUCTURE OF STREPTOCOCCUS PNEUMONIAE FATTY ACID KINASE (FAK) B1 PROTEIN LOADED WITH MYRISTIC ACID (C14:0) TO 1.69 ANGSTROM RESOLUTION
Descriptor:Fatty Acid Kinase (Fak) B1 protein, MYRISTIC ACID, SODIUM ION
Authors:Cuypers, M.G., Gullett, J.M., Subramanian, C., White, S.W., Rock, C.O.
Deposit date:2019-01-16
Release date:2019-08-21
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:The X-ray crystal structure of Streptococcus pneumoniae Fatty Acid Kinase (Fak) B1 protein loaded with myristic acid (C14:0) to 1.69 Angstrom resolution
To Be Published
6DKE
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THE X-RAY CRYSTAL STRUCTURE OF STREPTOCOCCUS PNEUMONIAE FATTY ACID KINASE (FAK) B1 PROTEIN LOADED WITH PALMITIC ACID (C16:0) TO 1.76 ANGSTROM RESOLUTION
Descriptor:Fatty Acid Kinase (Fak) B1 protein, PALMITIC ACID
Authors:Cuypers, M.G., Subramanian, C., White, S.W., Rock, C.O.
Deposit date:2018-05-29
Release date:2019-05-29
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:The X-ray crystal structure of Streptococcus pneumoniae Fatty Acid Kinase (Fak) B1 protein loaded with palmitic acid (C16:0) to 1.76 Angstrom resolution
To Be Published
6DJ6
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THE X-RAY CRYSTAL STRUCTURE OF THE STREPTOCOCCUS PNEUMONIAE FATTY ACID KINASE (FAK) B2 PROTEIN LOADED WITH CIS-OLEIC ACID TO 1.9 ANGSTROM RESOLUTION
Descriptor:Fatty Acid Kinase (Fak) B2 protein (SPR1019), GLYCEROL, OLEIC ACID, ...
Authors:Cuypers, M.G., Subramanian, C., White, S.W., Rock, C.O.
Deposit date:2018-05-24
Release date:2019-05-29
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The X-ray crystal structure of the Streptococcus pneumoniae Fatty Acid Kinase (Fak) B2 protein (SPR1019) loaded with cis-oleic acid to 1.9 Angstrom resolution
To Be Published
6CNG
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THE X-RAY CRYSTAL STRUCTURE OF THE STREPTOCOCCUS PNEUMONIAE FATTY ACID KINASE (FAK) B3 PROTEIN LOADED WITH LINOLEIC ACID TO 1.47 ANGSTROM RESOLUTION
Descriptor:Fatty Acid Kinase (Fak) B3 protein, LINOLEIC ACID, SODIUM ION, ...
Authors:Cuypers, M.G., Subramanian, C., White, S.W., Rock, C.O.
Deposit date:2018-03-08
Release date:2019-07-03
Method:X-RAY DIFFRACTION (1.47 Å)
Cite:The X-ray crystal structure of the Streptococcus pneumoniae Fatty Acid Kinase (Fak) B3 protein loaded with linoleic acid to 1.47 Angstrom resolution
To Be Published
6CLV
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STAPHYLOCOCCUS AUREUS DIHYDROPTEROATE SYNTHASE (SADHPS) F17L E208K DOUBLE MUTANT STRUCTURE
Descriptor:Dihydropteroate synthase, 4-{[(2-amino-4-oxo-3,4-dihydropteridin-6-yl)methyl]amino}-N-(3,4-dimethyl-1,2-oxazol-5-yl)benzene-1-sulfonamide
Authors:Gajewski, S., Griffith, E.C., Wu, Y., White, S.W.
Deposit date:2018-03-02
Release date:2018-08-22
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The Structural and Functional Basis for Recurring Sulfa Drug Resistance Mutations inStaphylococcus aureusDihydropteroate Synthase.
Front Microbiol, 9, 2018
6CLU
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STAPHYLOCOCCUS AUREUS DIHYDROPTEROATE SYNTHASE (SADHPS) F17L E208K DOUBLE MUTANT STRUCTURE
Descriptor:Dihydropteroate synthase
Authors:Gajewski, S., Griffith, E.C., Wu, Y., White, S.W.
Deposit date:2018-03-02
Release date:2018-08-22
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:The Structural and Functional Basis for Recurring Sulfa Drug Resistance Mutations inStaphylococcus aureusDihydropteroate Synthase.
Front Microbiol, 9, 2018
6B9I
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THE CRYSTAL STRUCTURE OF THE STAPHYLOCOCCUS AUREUS FATTY ACID KINASE (FAK) B1 PROTEIN LOADED WITH 14-METHYLHEXADECANOIC ACID (ANTEISO C17:0) TO 1.93 ANGSTROM RESOLUTION
Descriptor:Fatty acid Kinase (Fak) B1, (14S)-14-methylhexadecanoic acid, GLYCEROL, ...
Authors:Cuypers, M.G., Ericson, M., Subramanian, C., White, S.W., Rock, C.O.
Deposit date:2017-10-10
Release date:2018-10-10
Last modified:2019-01-16
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Acyl-chain selectivity and physiological roles ofStaphylococcus aureusfatty acid-binding proteins.
J. Biol. Chem., 294, 2019
6B3V
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PANK3 COMPLEX WITH COMPOUND PZ-2891
Descriptor:Pantothenate kinase 3, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, MAGNESIUM ION, ...
Authors:White, S.W., Yun, M.
Deposit date:2017-09-25
Release date:2018-08-29
Last modified:2018-11-28
Method:X-RAY DIFFRACTION (1.601 Å)
Cite:A therapeutic approach to pantothenate kinase associated neurodegeneration.
Nat Commun, 9, 2018
6ALW
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THE CRYSTAL STRUCTURE OF THE STAPHYLOCOCCUS AUREUS FATTY ACID KINASE (FAK) B1 PROTEIN LOADED WITH 12-METHYL MYRISTIC ACID (C15:0) TO 1.63 ANGSTROM RESOLUTION
Descriptor:EDD domain protein, DegV family, (12S)-12-methyltetradecanoic acid, ...
Authors:Cuypers, M.G., Ericson, M., Subramanian, C., White, S.W., Rock, C.O.
Deposit date:2017-08-08
Release date:2018-11-21
Last modified:2019-01-16
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:Acyl-chain selectivity and physiological roles ofStaphylococcus aureusfatty acid-binding proteins.
J. Biol. Chem., 294, 2019
5WOO
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THE CRYSTAL STRUCTURE OF THE STAPHYLOCOCCUS AUREUS FATTY ACID KINASE (FAK) B1 PROTEIN LOADED WITH MYRISTIC ACID (C14:0) TO 1.78 ANGSTROM RESOLUTION
Descriptor:EDD domain protein, DegV family, MYRISTIC ACID, ...
Authors:Cuypers, M.G., Ericson, M., Subramanian, C., White, S.W., Rock, C.O.
Deposit date:2017-08-02
Release date:2018-11-21
Last modified:2019-01-16
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Acyl-chain selectivity and physiological roles ofStaphylococcus aureusfatty acid-binding proteins.
J. Biol. Chem., 294, 2019
5V85
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THE CRYSTAL STRUCTURE OF THE PROTEIN OF DEGV FAMILY COG1307 FROM RUMINOCOCCUS GNAVUS ATCC 29149 (ALTERNATIVE REFINEMENT OF PDB 3JR7 WITH VACCENIC ACID)
Descriptor:EDD domain protein, DegV family, VACCENIC ACID, ...
Authors:Cuypers, M.G., Ericson, M., subramanian, C., White, S.W., Rock, C.O.
Deposit date:2017-03-21
Release date:2018-11-21
Method:X-RAY DIFFRACTION (2.003 Å)
Cite:The crystal structure of the Staphylococcus aureus Fatty acid Kinase (Fak) B1 protein loaded with palmitic acid to 1.83 Angstroem resolution
J.Biol.Chem., 2018
5UXY
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THE CRYSTAL STRUCTURE OF A DEGV FAMILY PROTEIN FROM EUBACTERIUM ELIGENS LOADED WITH HEPTADECANOIC ACID TO 1.80 ANGSTROM RESOLUTION (ALTERNATIVE REFINEMENT OF PDB 3FDJ WITH HEPTADECANOIC ACID)
Descriptor:DegV family protein, SODIUM ION, ACETIC ACID, ...
Authors:Cuypers, M.G., Ericson, M., subramanian, C., White, S.W., Rock, C.O.
Deposit date:2017-02-23
Release date:2018-11-21
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The crystal structure of the Staphylococcus aureus Fatty acid Kinase (Fak) B1 protein loaded with palmitic acid to 1.83 Angstroem resolution
J.Biol.Chem., 2018
5UTO
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THE CRYSTAL STRUCTURE OF THE STAPHYLOCOCCUS AUREUS FATTY ACID KINASE (FAK) B1 PROTEIN LOADED WITH PALMITIC ACID TO 1.83 ANGSTROM RESOLUTION
Descriptor:EDD domain protein, DegV family, PALMITIC ACID
Authors:Cuypers, M.G., Ericson, M., Subramanian, C., Broussard, T.C., Miller, D.J., White, S.W., Rock, C.O.
Deposit date:2017-02-15
Release date:2018-02-21
Last modified:2018-11-21
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:The crystal structure of the Staphylococcus aureus Fatty acid Kinase (Fak) B1 protein loaded with palmitic acid to 1.83 Angstroem resolution
J.Biol.Chem., 2018
5KYM
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CRYSTAL STRUCTURE OF THE 1-ACYL-SN-GLYCEROPHOSPHATE (LPA) ACYLTRANSFERASE, PLSC, FROM THERMOTOGA MARITIMA
Descriptor:1-acyl-sn-glycerol-3-phosphate acyltransferase, 1-HEPTADECANOYL-2-TRIDECANOYL-3-GLYCEROL-PHOSPHONYL CHOLINE, nonane, ...
Authors:Robertson, R.M., Yao, J., Gajewski, S., Kumar, G., Martin, E.W., Rock, C.O., White, S.W.
Deposit date:2016-07-21
Release date:2017-07-26
Last modified:2017-08-16
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:A two-helix motif positions the lysophosphatidic acid acyltransferase active site for catalysis within the membrane bilayer.
Nat. Struct. Mol. Biol., 24, 2017
5KQD
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PANK3:PALMITOYL-COA COMPLEX
Descriptor:Pantothenate kinase 3, Palmitoyl-CoA, SULFATE ION
Authors:White, S.W., Yun, M.
Deposit date:2016-07-06
Release date:2016-08-31
Last modified:2016-10-26
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Allosteric Regulation of Mammalian Pantothenate Kinase.
J.Biol.Chem., 291, 2016
5KQ8
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PANK3-AMPPN COMPLEX
Descriptor:Pantothenate kinase 3, AMP PHOSPHORAMIDATE, MAGNESIUM ION, ...
Authors:White, S.W., Yun, M.
Deposit date:2016-07-05
Release date:2016-08-31
Last modified:2016-10-26
Method:X-RAY DIFFRACTION (2.002 Å)
Cite:Allosteric Regulation of Mammalian Pantothenate Kinase.
J.Biol.Chem., 291, 2016