Author results

1EBL
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THE 1.8 A CRYSTAL STRUCTURE AND ACTIVE SITE ARCHITECTURE OF BETA-KETOACYL-[ACYL CARRIER PROTEIN] SYNTHASE III (FABH) FROM ESCHERICHIA COLI
Descriptor:BETA-KETOACYL-ACP SYNTHASE III, COENZYME A
Authors:Davies, C., Heath, R.J., White, S.W., Rock, C.O.
Deposit date:2000-01-24
Release date:2000-02-11
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The 1.8 A crystal structure and active-site architecture of beta-ketoacyl-acyl carrier protein synthase III (FabH) from escherichia coli.
Structure Fold.Des., 8, 2000
1ESM
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STRUCTURAL BASIS FOR THE FEEDBACK REGULATION OF ESCHERICHIA COLI PANTOTHENATE KINASE BY COENZYME A
Descriptor:PANTOTHENATE KINASE, COENZYME A
Authors:Yun, M., Park, C.G., Kim, J.Y., Rock, C.O., Jackowski, S., Park, H.W.
Deposit date:2000-04-10
Release date:2000-09-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis for the feedback regulation of Escherichia coli pantothenate kinase by coenzyme A.
J.Biol.Chem., 275, 2000
1ESN
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STRUCTURAL BASIS FOR THE FEEDBACK REGULATION OF ESCHERICHIA COLI PANTOTHENATE KINASE BY COENZYME A
Descriptor:PANTOTHENATE KINASE, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
Authors:Yun, M., Park, C.G., Kim, J.Y., Rock, C.O., Jackowski, S., Park, H.W.
Deposit date:2000-04-10
Release date:2000-11-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural basis for the feedback regulation of Escherichia coli pantothenate kinase by coenzyme A.
J.Biol.Chem., 275, 2000
1FJ4
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THE STRUCTURE OF BETA-KETOACYL-[ACYL CARRIER PROTEIN] SYNTHASE I IN COMPLEX WITH THIOLACTOMYCIN, IMPLICATIONS FOR DRUG DESIGN
Descriptor:BETA-KETOACYL-[ACYL CARRIER PROTEIN] SYNTHASE I, THIOLACTOMYCIN
Authors:Price, A.C., Choi, K., Heath, R.J., Li, Z., White, S.W., Rock, C.O.
Deposit date:2000-08-07
Release date:2000-08-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Inhibition of beta-ketoacyl-acyl carrier protein synthases by thiolactomycin and cerulenin. Structure and mechanism.
J.Biol.Chem., 276, 2001
1FJ8
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THE STRUCTURE OF BETA-KETOACYL-[ACYL CARRIER PROTEIN] SYNTHASE I IN COMPLEX WITH CERULENIN, IMPLICATIONS FOR DRUG DESIGN
Descriptor:BETA-KETOACYL-[ACYL CARRIER PROTEIN] SYNTHASE I, (2S, 3R)-3-HYDROXY-4-OXO-7,10-TRANS,TRANS-DODECADIENAMIDE
Authors:Price, A.C., Choi, K., Heath, R.J., Li, Z., White, S.W., Rock, C.O.
Deposit date:2000-08-07
Release date:2000-08-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:Inhibition of beta-ketoacyl-acyl carrier protein synthases by thiolactomycin and cerulenin. Structure and mechanism.
J.Biol.Chem., 276, 2001
1G5X
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THE STRUCTURE OF BETA-KETOACYL-[ACYL CARRIER PROTEIN] SYNTHASE I
Descriptor:BETA-KETOACYL ACYL CARRIER PROTEIN SYNTHASE I
Authors:Zhang, Y.M., Rao, M.S., Heath, R.J., Price, A.C., Olson, A.J., Rock, C.O., White, S.W.
Deposit date:2000-11-02
Release date:2000-11-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Identification and analysis of the acyl carrier protein (ACP) docking site on beta-ketoacyl-ACP synthase III.
J.Biol.Chem., 276, 2001
1HW1
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THE FADR-DNA COMPLEX: TRANSCRIPTIONAL CONTROL OF FATTY ACID METABOLISM IN ESCHERICHIA COLI
Descriptor:FATTY ACID METABOLISM REGULATOR PROTEIN, SULFATE ION, ZINC ION
Authors:Xu, Y., Heath, R.J., Li, Z., Rock, C.O., White, S.W.
Deposit date:2001-01-09
Release date:2001-01-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:The FadR.DNA complex. Transcriptional control of fatty acid metabolism in Escherichia coli.
J.Biol.Chem., 276, 2001
1HW2
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FADR-DNA COMPLEX: TRANSCRIPTIONAL CONTROL OF FATTY ACID METABOLISM IN ECHERICHIA COLI
Descriptor:5'-D(*CP*GP*AP*TP*CP*TP*GP*GP*TP*CP*CP*GP*AP*CP*CP*AP*GP*AP*TP*GP*CP*T)-3', 5'-D(*G*CP*AP*TP*CP*TP*GP*GP*TP*CP*GP*GP*AP*CP*CP*AP*GP*AP*TP*CP*GP*A)-3', FATTY ACID METABOLISM REGULATOR PROTEIN, ...
Authors:Xu, Y., Heath, R.J., Li, Z., Rock, C.O., White, S.W.
Deposit date:2001-01-09
Release date:2001-01-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:The FadR.DNA complex. Transcriptional control of fatty acid metabolism in Escherichia coli.
J.Biol.Chem., 276, 2001
1I01
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CRYSTAL STRUCTURE OF BETA-KETOACYL [ACYL CARRIER PROTEIN] REDUCTASE FROM E. COLI.
Descriptor:BETA-KETOACYL [ACP] REDUCTASE
Authors:Price, A.C., Rock, C.O., White, S.W.
Deposit date:2001-01-27
Release date:2001-02-07
Last modified:2014-11-12
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of beta-ketoacyl-[acyl carrier protein] reductase from Escherichia coli: negative cooperativity and its structural basis.
Biochemistry, 40, 2001
1KLP
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THE SOLUTION STRUCTURE OF ACYL CARRIER PROTEIN FROM MYCOBACTERIUM TUBERCULOSIS
Descriptor:MEROMYCOLATE EXTENSION ACYL CARRIER PROTEIN
Authors:Wong, H.C., Liu, G., Zhang, Y.-M., Rock, C.O., Zheng, J.
Deposit date:2001-12-12
Release date:2002-06-07
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:The solution structure of acyl carrier protein from Mycobacterium tuberculosis.
J.Biol.Chem., 277, 2002
1M7E
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CRYSTAL STRUCTURE OF THE PHOSPHOTYROSINE BINDING DOMAIN(PTB) OF MOUSE DISABLED 2(DAB2):IMPLICATIONS FOR REELING SIGNALING
Descriptor:Disabled homolog 2, NGYENPTYK peptide
Authors:Yun, M., Keshvara, L., Park, C.-G., Zhang, Y.-M., Dickerson, J.B., Zheng, J., Rock, C.O., Curran, T., Park, H.-W.
Deposit date:2002-07-19
Release date:2003-08-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Crystal structures of the Dab homology domains of mouse disabled 1 and 2
J.Biol.Chem., 278, 2003
1OQN
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CRYSTAL STRUCTURE OF THE PHOSPHOTYROSINE BINDING DOMAIN (PTB) OF MOUSE DISABLED 1 (DAB1)
Descriptor:Disabled homolog 1, Alzheimer's disease amyloid A4 protein homolog, D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE
Authors:Yun, M., Keshvara, L., Park, C.-G., Zhang, Y.-M., Dickerson, J.B., Zheng, J., Rock, C.O., Curran, T., Park, H.-W.
Deposit date:2003-03-10
Release date:2003-08-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structures of the Dab homology domains of mouse disabled 1 and 2
J.Biol.Chem., 278, 2003
1OX0
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THE CRYSTAL STRUCTURE OF BETA-KETOACYL-[ACYL CARRIER PROTEIN] SYNTHASE II FROM STREPTOCOCCUS PNEUMONIAE
Descriptor:Beta ketoacyl-acyl carrier protein synthase, MAGNESIUM ION
Authors:Price, A.C., Rock, C.O., White, S.W.
Deposit date:2003-03-31
Release date:2003-04-22
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:The 1.3-Angstrom-Resolution Crystal Structure of beta-Ketoacyl-Acyl Carrier Protein Synthase II from Streptococcus pneumoniae.
J.Bacteriol., 185, 2003
1OXH
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THE CRYSTAL STRUCTURE OF BETA-KETOACYL-[ACYL CARRIER PROTEIN] SYNTHASE II FROM STREPTOCOCCUS PNEUMONIAE, TRICLINIC FORM
Descriptor:Beta ketoacyl-acyl carrier protein synthase, MAGNESIUM ION
Authors:Price, A.C., Rock, C.O., White, S.W.
Deposit date:2003-04-02
Release date:2003-04-22
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:The 1.3-Angstrom-Resolution Crystal Structure of beta-Ketoacyl-Acyl Carrier Protein Synthase II from Streptococcus pneumoniae.
J.Bacteriol., 185, 2003
1P3R
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CRYSTAL STRUCTURE OF THE PHOSPHOTYROSIN BINDING DOMAIN(PTB) OF MOUSE DISABLED 1(DAB1)
Descriptor:Disabled homolog 2
Authors:Yun, M., Keshvara, L., Park, C.G., Zhang, Y.M., Dickerson, J.B., Zheng, J., Rock, C.O., Curran, T., Park, H.W.
Deposit date:2003-04-18
Release date:2003-08-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structures of the Dab homology domains of mouse disabled 1 and 2.
J.Biol.Chem., 278, 2003
1Q7B
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THE STRUCTURE OF BETAKETOACYL-[ACP] REDUCTASE FROM E. COLI IN COMPLEX WITH NADP+
Descriptor:3-oxoacyl-[acyl-carrier protein] reductase, CALCIUM ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Price, A.C., Zhang, Y.-M., Rock, C.O., White, S.M.
Deposit date:2003-08-17
Release date:2004-02-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Cofactor-Induced Conformational Rearrangements Establish a Catalytically Competent Active Site and a Proton Relay Conduit in FabG
Structure, 12, 2004
1Q7C
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THE STRUCTURE OF BETAKETOACYL-[ACP] REDUCTASE Y151F MUTANT IN COMPLEX WITH NADPH FRAGMENT
Descriptor:3-oxoacyl-[acyl-carrier protein] reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Price, A.C., Zhang, Y.-M., Rock, C.O., White, S.M.
Deposit date:2003-08-17
Release date:2004-02-17
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Cofactor-Induced Conformational Rearrangements Establish a Catalytically Competent Active Site and a Proton Relay Conduit in FabG
Structure, 12, 2004
1SQ5
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CRYSTAL STRUCTURE OF E. COLI PANTOTHENATE KINASE
Descriptor:Pantothenate kinase, PANTOTHENOIC ACID, ADENOSINE-5'-DIPHOSPHATE
Authors:Ivey, R.A., Zhang, Y.-M., Virga, K.G., Hevener, K., Lee, R.E., Rock, C.O., Jackowski, S., Park, H.-W.
Deposit date:2004-03-17
Release date:2004-09-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The structure of the pantothenate kinase.ADP.pantothenate ternary complex reveals the relationship between the binding sites for substrate, allosteric regulator, and antimetabolites.
J.Biol.Chem., 279, 2004
1U1Z
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THE STRUCTURE OF (3R)-HYDROXYACYL-ACP DEHYDRATASE (FABZ)
Descriptor:(3R)-hydroxymyristoyl-[acyl carrier protein] dehydratase, SULFATE ION
Authors:Kimber, M.S., Martin, F., Lu, Y., Houston, S., Vedadi, M., Dharamsi, A., Fiebig, K.M., Schmid, M., Rock, C.O.
Deposit date:2004-07-16
Release date:2004-09-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The Structure of (3R)-hydroxyacyl-acyl carrier protein dehydratase (FabZ) from Pseudomonas aeruginosa
J.Biol.Chem., 279, 2004
2ALM
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CRYSTAL STRUCTURE ANALYSIS OF A MUTANT BETA-KETOACYL-[ACYL CARRIER PROTEIN] SYNTHASE II FROM STREPTOCOCCUS PNEUMONIAE
Descriptor:3-oxoacyl-(acyl-carrier-protein) synthase II, MAGNESIUM ION
Authors:Zhang, Y.M., Hurlbert, J., White, S.W., Rock, C.O.
Deposit date:2005-08-07
Release date:2005-08-30
Last modified:2011-11-16
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Roles of the active site water, histidine 303, and phenylalanine 396 in the catalytic mechanism of the elongation condensing enzyme of Streptococcus pneumoniae.
J.Biol.Chem., 281, 2006
2F9T
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STRUCTURE OF THE TYPE III COAA FROM PSEUDOMONAS AERUGINOSA
Descriptor:Pantothenate Kinase
Authors:Leonardi, R., Yun, M.K., Chohnan, S., White, S.W., Rock, C.O., Jackowski, S.
Deposit date:2005-12-06
Release date:2006-08-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Prokaryotic Type II and Type III Pantothenate Kinases: The Same Monomer Fold Creates Dimers with Distinct Catalytic Properties.
Structure, 14, 2006
2F9W
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STRUCTURE OF THE TYPE III COAA FROM PSEUDOMONAS AERUGINOSA
Descriptor:Pantothenate Kinase, PANTOTHENOIC ACID, 1,2-ETHANEDIOL, ...
Authors:Leonardi, R., Yun, M.K., Chohnan, S., White, S.W., Rock, C.O., Jackowski, S.
Deposit date:2005-12-06
Release date:2006-08-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Prokaryotic Type II and Type III Pantothenate Kinases: The Same Monomer Fold Creates Dimers with Distinct Catalytic Properties.
Structure, 14, 2006
2GQD
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THE CRYSTAL STRUCTURE OF B-KETOACYL-ACP SYNTHASE II (FABF) FROM STAPHYLOCOCCUS AUREUS
Descriptor:3-oxoacyl-[acyl-carrier-protein] synthase 2
Authors:Miller, D.J., White, S.W., Zhang, Y.M., Rock, C.O.
Deposit date:2006-04-20
Release date:2006-05-02
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The crystal structure of B-ketoacyl-ACP synthase II (FabF) from Staphylococcus aureus
To be Published
2HIM
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CRYSTAL STRUCTURE AND ALLOSTERIC REGULATION OF THE CYTOPLASMIC ESCHERICHIA COLI L-ASPARAGINASE I
Descriptor:L-asparaginase 1, ASPARTIC ACID, ASPARAGINE, ...
Authors:Yun, M.K., Nourse, A., White, S.W., Rock, C.O., Heath, R.J.
Deposit date:2006-06-29
Release date:2007-05-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:Crystal Structure and Allosteric Regulation of the Cytoplasmic Escherichia coli L-Asparaginase I.
J.Mol.Biol., 369, 2007
2P2D
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CRYSTAL STRUCTURE AND ALLOSTERIC REGULATION OF THE CYTOPLASMIC ESCHERICHIA COLI L-ASPARAGINASE I
Descriptor:L-ASPARAGINASE I, GLYCEROL
Authors:Yun, M.-K., Nourse, A., White, S.W., Rock, C.O., Heath, R.J.
Deposit date:2007-03-07
Release date:2007-05-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Crystal Structure and Allosteric Regulation of the Cytoplasmic Escherichia colil-Asparaginase I
J.Mol.Biol., 369, 2007
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