Author results

6HUD
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CRYO-EM STRUCTURE OF CARDIAC AMYLOID FIBRILS FROM AN IMMUNOGLOBULIN LIGHT CHAIN (AL) AMYLOIDOSIS PATIENT.
Descriptor:Monoclonal immunoglobulin light chains (LC)
Authors:Paissoni, C., Camilloni, C.
Deposit date:2018-10-06
Release date:2019-03-27
Last modified:2019-04-03
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Cryo-EM structure of cardiac amyloid fibrils from an immunoglobulin light chain AL amyloidosis patient.
Nat Commun, 10, 2019
5MTL
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CRYSTAL STRUCTURE OF AN AMYLOIDOGENIC LIGHT CHAIN
Descriptor:light chain dimer,IGL@ protein,IGL@ protein
Authors:Oberti, L., Rognoni, P., Russo, R., Bacarizo, J., Bolognesi, M., Ricagno, S.
Deposit date:2017-01-10
Release date:2017-12-13
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Concurrent structural and biophysical traits link with immunoglobulin light chains amyloid propensity.
Sci Rep, 7, 2017
5MUD
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CRYSTAL STRUCTURE OF AN AMYLOIDOGENIC LIGHT CHAIN DIMER H6
Descriptor:light chain dimer,IGL@ protein
Authors:Oberti, L., Bacarizo, J., Maritan, M., Rognoni, P., Bolognesi, M., Ricagno, S.
Deposit date:2017-01-13
Release date:2017-12-13
Method:X-RAY DIFFRACTION (2.34 Å)
Cite:Concurrent structural and biophysical traits link with immunoglobulin light chains amyloid propensity.
Sci Rep, 7, 2017
5MUH
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CRYSTAL STRUCTURE OF AN AMYLOIDOGENIC LIGHT CHAIN DIMER H7
Descriptor:light chain dimer
Authors:Oberti, L., Rognoni, P., Russo, R., Maritan, M., Bacarizo, J., Bolognesi, M., Ricagno, S.
Deposit date:2017-01-13
Release date:2017-12-13
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Concurrent structural and biophysical traits link with immunoglobulin light chains amyloid propensity.
Sci Rep, 7, 2017
5MVG
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CRYSTAL STRUCTURE OF NON-AMYLOIDOGENIC LIGHT CHAIN DIMER M7
Descriptor:light chain dimer, GLYCEROL
Authors:Oberti, L., Rognoni, P., Bacarizo, J., Bolognesi, M., Ricagno, S.
Deposit date:2017-01-16
Release date:2017-12-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Concurrent structural and biophysical traits link with immunoglobulin light chains amyloid propensity.
Sci Rep, 7, 2017
5M6A
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CRYSTAL STRUCTURE OF CARDIOTOXIC BENCE-JONES LIGHT CHAIN DIMER H9
Descriptor:Bence-Jones light chain, GLYCEROL, PHOSPHATE ION
Authors:Oberti, L., Rognoni, P., Bacarizo, J., Bolognesi, M., Ricagno, S.
Deposit date:2016-10-24
Release date:2017-11-15
Last modified:2017-12-13
Method:X-RAY DIFFRACTION (1.64 Å)
Cite:Concurrent structural and biophysical traits link with immunoglobulin light chains amyloid propensity.
Sci Rep, 7, 2017
5M6I
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CRYSTAL STRUCTURE OF NON-CARDIOTOXIC BENCE-JONES LIGHT CHAIN DIMER M8
Descriptor:light chain dimer, SODIUM ION
Authors:Oberti, L., Rognoni, P., Russo, R., Bacarizo, J., Bolognesi, M., Ricagno, S.
Deposit date:2016-10-25
Release date:2017-11-15
Last modified:2017-12-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Concurrent structural and biophysical traits link with immunoglobulin light chains amyloid propensity.
Sci Rep, 7, 2017
5M76
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CRYSTAL STRUCTURE OF CARDIOTOXIC BENCE-JONES LIGHT CHAIN DIMER H10
Descriptor:light chain dimer, BROMIDE ION
Authors:Oberti, L., Rognoni, P., Bacarizo, J., Bolognesi, M., Ricagno, S.
Deposit date:2016-10-26
Release date:2017-11-15
Last modified:2017-12-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Concurrent structural and biophysical traits link with immunoglobulin light chains amyloid propensity.
Sci Rep, 7, 2017
5LLL
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CRYSTAL STRUCTURE OF DACM WILD TYPE TRANSTHYRETIN
Descriptor:Transthyretin
Authors:Sala, B.M., Ghadami, S.A., Bemporad, F., Chiti, F., Ricagno, S.
Deposit date:2016-07-27
Release date:2017-06-07
Last modified:2017-12-13
Method:X-RAY DIFFRACTION (1.42 Å)
Cite:FRET studies of various conformational states adopted by transthyretin.
Cell. Mol. Life Sci., 74, 2017
5LLV
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CRYSTAL STRUCTURE OF DACM F87M/L110M TRANSTHYRETIN MUTANT
Descriptor:Transthyretin, CHLORIDE ION, ACETATE ION
Authors:Sala, B.M., Ghadami, S.A., Bemporad, F., Chiti, F., Ricagno, S.
Deposit date:2016-07-28
Release date:2017-06-07
Last modified:2017-12-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:FRET studies of various conformational states adopted by transthyretin.
Cell. Mol. Life Sci., 74, 2017
5FAE
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N184K PATHOLOGICAL VARIANT OF GELSOLIN DOMAIN 2 (TRIGONAL FORM)
Descriptor:Gelsolin, CALCIUM ION, SULFATE ION, ...
Authors:Boni, F., Milani, M., Ricagno, S., Bolognesi, M., de Rosa, M.
Deposit date:2015-12-11
Release date:2016-10-05
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Molecular basis of a novel renal amyloidosis due to N184K gelsolin variant.
Sci Rep, 6, 2016
5FAF
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N184K PATHOLOGICAL VARIANT OF GELSOLIN DOMAIN 2 (ORTHORHOMBIC FORM)
Descriptor:Gelsolin, CALCIUM ION, GLYCEROL, ...
Authors:Boni, F., Milani, M., Ricagno, s., Bolognesi, M., de Rosa, M.
Deposit date:2015-12-11
Release date:2016-10-05
Method:X-RAY DIFFRACTION (1.05 Å)
Cite:Molecular basis of a novel renal amyloidosis due to N184K gelsolin variant.
Sci Rep, 6, 2016
5LP6
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CRYSTAL STRUCTURE OF TUBULIN-STATHMIN-TTL-THIOCOLCHICINE COMPLEX
Descriptor:Tubulin alpha-1B chain, Tubulin beta-2B chain, Stathmin-4, ...
Authors:Marangon, J., Christodoulou, M., Casagrande, F., Tiana, G., Dalla Via, L., Aliverti, A., Passarella, D., Cappelletti, G., Ricagno, S.
Deposit date:2016-08-11
Release date:2016-09-21
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Tools for the rational design of bivalent microtubule-targeting drugs.
Biochem. Biophys. Res. Commun., 479, 2016
5CS7
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THE CRYSTAL STRUCTURE OF WT BETA2-MICROGLOBULIN AT ROOM TEMPERATURE
Descriptor:Beta-2-microglobulin
Authors:de Rosa, M., Mota, C.S., de Sanctis, D., Bolognesi, M., Ricagno, S.
Deposit date:2015-07-23
Release date:2016-08-10
Last modified:2018-06-27
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Conformational dynamics in crystals reveal the molecular bases for D76N beta-2 microglobulin aggregation propensity.
Nat Commun, 9, 2018
5CSB
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THE CRYSTAL STRUCTURE OF BETA2-MICROGLOBULIN D76N MUTANT AT ROOM TEMPERATURE
Descriptor:Beta-2-microglobulin
Authors:de Rosa, M., Mota, C.S., de Sanctis, D., Bolognesi, M., Ricagno, S.
Deposit date:2015-07-23
Release date:2016-08-10
Last modified:2018-06-27
Method:X-RAY DIFFRACTION (1.719 Å)
Cite:Conformational dynamics in crystals reveal the molecular bases for D76N beta-2 microglobulin aggregation propensity.
Nat Commun, 9, 2018
5CSG
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THE CRYSTAL STRUCTURE OF BETA2-MICROGLOBULIN R97Q MUTANT
Descriptor:Beta-2-microglobulin, ACETATE ION
Authors:de Rosa, M., Bolognesi, M., Ricagno, S.
Deposit date:2015-07-23
Release date:2016-08-10
Last modified:2018-06-27
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Conformational dynamics in crystals reveal the molecular bases for D76N beta-2 microglobulin aggregation propensity.
Nat Commun, 9, 2018
5CFH
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HUMAN BETA-2 MICROGLOBULIN DOUBLE MUTANT W60G-Y63W
Descriptor:Beta-2-microglobulin
Authors:Sala, B.M., De Rosa, M., Bolognesi, M., Ricagno, S.
Deposit date:2015-07-08
Release date:2016-05-18
Method:X-RAY DIFFRACTION (1.49 Å)
Cite:Rational design of mutations that change the aggregation rate of a protein while maintaining its native structure and stability.
Sci Rep, 6, 2016
5CKA
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HUMAN BETA-2 MICROGLOBULIN DOUBLE MUTANT W60G-N83V
Descriptor:Beta-2-microglobulin, GLYCEROL, ACETATE ION, ...
Authors:Sala, B.M., De Rosa, M., Bolognesi, M., Ricagno, S.
Deposit date:2015-07-15
Release date:2016-05-18
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Rational design of mutations that change the aggregation rate of a protein while maintaining its native structure and stability.
Sci Rep, 6, 2016
5CKG
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HUMAN BETA-2 MICROGLOBULIN MUTANT V85E
Descriptor:Beta-2-microglobulin, ACETATE ION, GLYCEROL
Authors:Sala, B.M., De Rosa, M., Bolognesi, M., Ricagno, S.
Deposit date:2015-07-15
Release date:2016-05-18
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Rational design of mutations that change the aggregation rate of a protein while maintaining its native structure and stability.
Sci Rep, 6, 2016
4RMQ
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CRYSTAL STRUCTURE OF THE D59N BETA-2 MICROGLOBULIN MUTANT
Descriptor:Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER
Authors:de Rosa, M., Bolognesi, M., Ricagno, S.
Deposit date:2014-10-22
Release date:2015-11-18
Last modified:2015-12-09
Method:X-RAY DIFFRACTION (1.461 Å)
Cite:Decoding the Structural Bases of D76N 2-Microglobulin High Amyloidogenicity through Crystallography and Asn-Scan Mutagenesis.
Plos One, 10, 2015
4RMR
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CRYSTAL STRUCTURE OF THE D38N BETA-2 MICROGLOBULIN MUTANT
Descriptor:Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, ACETATE ION
Authors:de Rosa, M., Bolognesi, M., Ricagno, S.
Deposit date:2014-10-22
Release date:2015-11-18
Last modified:2015-12-09
Method:X-RAY DIFFRACTION (1.529 Å)
Cite:Decoding the Structural Bases of D76N 2-Microglobulin High Amyloidogenicity through Crystallography and Asn-Scan Mutagenesis.
Plos One, 10, 2015
4RMS
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CRYSTAL STRUCTURE OF THE D53N BETA-2 MICROGLOBULIN MUTANT
Descriptor:Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, ACETATE ION
Authors:de Rosa, M., Bolognesi, M., Ricagno, S.
Deposit date:2014-10-22
Release date:2015-11-18
Last modified:2015-12-09
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Decoding the Structural Bases of D76N 2-Microglobulin High Amyloidogenicity through Crystallography and Asn-Scan Mutagenesis.
Plos One, 10, 2015
4RMT
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CRYSTAL STRUCTURE OF THE D98N BETA-2 MICROGLOBULIN MUTANT
Descriptor:Beta-2-microglobulin, TRIETHYLENE GLYCOL, DI(HYDROXYETHYL)ETHER, ...
Authors:de Rosa, M., Bolognesi, M., Ricagno, S.
Deposit date:2014-10-22
Release date:2015-11-18
Last modified:2015-12-09
Method:X-RAY DIFFRACTION (1.242 Å)
Cite:Decoding the Structural Bases of D76N 2-Microglobulin High Amyloidogenicity through Crystallography and Asn-Scan Mutagenesis.
Plos One, 10, 2015
4RMU
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CRYSTAL STRUCTURE OF THE D76E BETA-2 MICROGLOBULIN MUTANT
Descriptor:Beta-2-microglobulin, TRIETHYLENE GLYCOL
Authors:de Rosa, M., Bolognesi, M., Ricagno, S.
Deposit date:2014-10-22
Release date:2015-11-18
Last modified:2018-06-27
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Conformational dynamics in crystals reveal the molecular bases for D76N beta-2 microglobulin aggregation propensity.
Nat Commun, 9, 2018
4RMV
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CRYSTAL STRUCTURE OF THE D76H BETA-2 MICROGLOBULIN MUTANT
Descriptor:Beta-2-microglobulin, ACETATE ION, TRIETHYLENE GLYCOL
Authors:de Rosa, M., Bolognesi, M., Ricagno, S.
Deposit date:2014-10-22
Release date:2015-11-18
Last modified:2018-06-27
Method:X-RAY DIFFRACTION (1.463 Å)
Cite:Conformational dynamics in crystals reveal the molecular bases for D76N beta-2 microglobulin aggregation propensity.
Nat Commun, 9, 2018
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