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2VQI
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STRUCTURE OF THE P PILUS USHER (PAPC) TRANSLOCATION PORE
Descriptor:OUTER MEMBRANE USHER PROTEIN PAPC, LAURYL DIMETHYLAMINE-N-OXIDE, (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE
Authors:Remaut, H., Tang, C., Henderson, N.S., Pinkner, J.S., Wang, T., Hultgren, S.J., Thanassi, D.G., Li, H., Waksman, G.
Deposit date:2008-03-16
Release date:2008-05-27
Last modified:2019-01-16
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Fiber formation across the bacterial outer membrane by the chaperone/usher pathway.
Cell, 133, 2008
1HI9
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ZN-DEPENDENT D-AMINOPEPTIDASE DPPA FROM BACILLUS SUBTILIS, A SELF-COMPARTMENTALIZING PROTEASE.
Descriptor:DIPEPTIDE TRANSPORT PROTEIN DPPA, ZINC ION
Authors:Remaut, H., Bompard-Gilles, C., Goffin, C., Frere, J.M., Van Beeumen, J.
Deposit date:2001-01-04
Release date:2001-08-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of the Bacillus Subtilis D-Aminopeptidase Dppa Reveals a Novel Self-Compartmentalizing Protease
Nat.Struct.Biol., 8, 2001
2CNY
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SALMONELLA ENTERICA SAFA PILIN IN COMPLEX WITH A 19-RESIDUE SAFA NTE PEPTIDE (I15A MUTANT)
Descriptor:PUTATIVE OUTER MEMBRANE PROTEIN
Authors:Remaut, H., Rose, R.J., Hannan, T.J., Hultgren, S.J., Radford, S.E., Ashcroft, A.E., Waksman, G.
Deposit date:2006-05-25
Release date:2006-06-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Donor-Strand Exchange in Chaperone-Assisted Pilus Assembly Proceeds Through a Concerted Beta-Strand Displacement Mechanism
Mol.Cell, 22, 2006
2CNZ
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SALMONELLA ENTERICA SAFA PILIN IN COMPLEX WITH A 19-RESIDUE SAFA NTE PEPTIDE (V13A MUTANT)
Descriptor:PUTATIVE OUTER MEMBRANE PROTEIN
Authors:Remaut, H., Rose, R.J., Hannan, T.J., Hultgren, S.J., Radford, S.E., Ashcroft, A.E., Waksman, G.
Deposit date:2006-05-25
Release date:2006-06-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Donor-Strand Exchange in Chaperone-Assisted Pilus Assembly Proceeds Through a Concerted Beta-Strand Displacement Mechanism
Mol.Cell, 22, 2006
2CO1
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SALMONELLA ENTERICA SAFA PILIN IN COMPLEX WITH A 19-RESIDUE SAFA NTE PEPTIDE (F17A MUTANT)
Descriptor:PUTATIVE OUTER MEMBRANE PROTEIN
Authors:Remaut, H., Rose, R.J., Hannan, T.J., Hultgren, S.J., Radford, S.E., Ashcroft, A.E., Waksman, G.
Deposit date:2006-05-25
Release date:2006-06-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Donor-Strand Exchange in Chaperone-Assisted Pilus Assembly Proceeds Through a Concerted Beta-Strand Displacement Mechanism
Mol.Cell, 22, 2006
2CO2
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SALMONELLA ENTERICA SAFA PILIN IN COMPLEX WITH A 19-RESIDUE SAFA NTE PEPTIDE (F3A MUTANT)
Descriptor:SAFA PILUS SUBUNIT, SAFA N-TERMINAL EXTENSION
Authors:Remaut, H., Rose, R.J., Hannan, T.J., Hultgren, S.J., Radford, S.E., Ashcroft, A.E., Waksman, G.
Deposit date:2006-05-25
Release date:2006-06-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Donor-Strand Exchange in Chaperone-Assisted Pilus Assembly Proceeds Through a Concerted Beta-Strand Displacement Mechanism
Mol.Cell, 22, 2006
2CO3
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SALMONELLA ENTERICA SAFA PILIN, HEAD-TO-TAIL SWAPPED DIMER OF NTD1 MUTANT
Descriptor:SAFA PILUS SUBUNIT
Authors:Remaut, H., Rose, R.J., Hannan, T.J., Hultgren, S.J., Radford, S.E., Ashcroft, A.E., Waksman, G.
Deposit date:2006-05-25
Release date:2006-06-27
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Donor-Strand Exchange in Chaperone-Assisted Pilus Assembly Proceeds Through a Concerted Beta-Strand Displacement Mechanism
Mol.Cell, 22, 2006
2CO4
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SALMONELLA ENTERICA SAFA PILIN IN COMPLEX WITH A 19-RESIDUE SAFA NTE PEPTIDE
Descriptor:PUTATIVE OUTER MEMBRANE PROTEIN
Authors:Remaut, H., Rose, R.J., Hannan, T.J., Hultgren, S.J., Radford, S.E., Ashcroft, A.E., Waksman, G.
Deposit date:2006-05-25
Release date:2006-06-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Donor-Strand Exchange in Chaperone-Assisted Pilus Assembly Proceeds Through a Concerted Beta-Strand Displacement Mechanism
Mol.Cell, 22, 2006
2CO6
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SALMONELLA ENTERICA SAFA PILIN IN COMPLEX WITH THE SAFB CHAPERONE (TYPE I)
Descriptor:PUTATIVE OUTER MEMBRANE PROTEIN, PUTATIVE FIMBRIAE ASSEMBLY CHAPERONE
Authors:Remaut, H., Rose, R.J., Hannan, T.J., Hultgren, S.J., Radford, S.E., Ashcroft, A.E., Waksman, G.
Deposit date:2006-05-25
Release date:2006-06-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Donor-Strand Exchange in Chaperone-Assisted Pilus Assembly Proceeds Through a Concerted Beta-Strand Displacement Mechanism
Mol.Cell, 22, 2006
2CO7
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SALMONELLA ENTERICA SAFA PILIN IN COMPLEX WITH THE SAFB CHAPERONE (TYPE II)
Descriptor:SAFA PILUS SUBUNIT, PUTATIVE FIMBRIAE ASSEMBLY CHAPERONE, SULFATE ION
Authors:Remaut, H., Rose, R.J., Hannan, T.J., Hultgren, S.J., Radford, S.E., Ashcroft, A.E., Waksman, G.
Deposit date:2006-05-25
Release date:2006-06-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Donor-Strand Exchange in Chaperone-Assisted Pilus Assembly Proceeds Through a Concerted Beta-Strand Displacement Mechanism
Mol.Cell, 22, 2006
2J7L
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E. COLI P PILUS CHAPERONE PAPD IN COMPLEX WITH A PILUS BIOGENESIS INHIBITOR, PILICIDE 2C
Descriptor:CHAPERONE PROTEIN PAPD, (3R)-8-CYCLOPROPYL-6-(MORPHOLIN-4-YLMETHYL)-7-(1-NAPHTHYLMETHYL)-5-OXO-2,3-DIHYDRO-5H-[1,3]THIAZOLO[3,2-A]PYRIDINE-3-CARBOXYLIC ACID
Authors:Remaut, H., Pinkner, J.S., Hultgren, S.J., Almqvist, F., Waksman, G.
Deposit date:2006-10-12
Release date:2006-11-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Rationally Designed Small Compounds Inhibit Pilus Biogenesis in Uropathogenic Bacteria.
Proc.Natl.Acad.Sci.USA, 103, 2006
2XG4
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E. COLI P PILUS CHAPERONE-SUBUNIT COMPLEX PAPD-PAPH BOUND TO PILUS BIOGENESIS INHIBITOR, PILICIDE 2C
Descriptor:CHAPERONE PROTEIN PAPD, PAP FIMBRIAL MINOR PILIN PROTEIN, (3R)-8-CYCLOPROPYL-6-(MORPHOLIN-4-YLMETHYL)-7-(1-NAPHTHYLMETHYL)-5-OXO-2,3-DIHYDRO-5H-[1,3]THIAZOLO[3,2-A]PYRIDINE-3-CARBOXYLIC ACID, ...
Authors:Remaut, H., Phan, G., Buelens, F., Chorell, E., Pinkner, J.S., Edvinsson, S., Almqvist, F., Hultgren, S.J., Waksman, G.
Deposit date:2010-05-30
Release date:2010-07-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Design and Synthesis of C-2 Substituted Thiazolo and Dihydrothiazolo Ring-Fused 2-Pyridones: Pilicides with Increased Antivirulence Activity.
J.Med.Chem., 53, 2010
2XG5
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E. COLI P PILUS CHAPERONE-SUBUNIT COMPLEX PAPD-PAPH BOUND TO PILUS BIOGENESIS INHIBITOR, PILICIDE 5D
Descriptor:CHAPERONE PROTEIN PAPD, PAP FIMBRIAL MINOR PILIN PROTEIN, GLYCEROL, ...
Authors:Remaut, H., Phan, G., Buelens, F., Chorell, E., Pinkner, J.S., Edvinsson, S., Almqvist, F., Hultgren, S.J., Waksman, G.
Deposit date:2010-05-30
Release date:2010-07-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Design and Synthesis of C-2 Substituted Thiazolo and Dihydrothiazolo Ring-Fused 2-Pyridones: Pilicides with Increased Antivirulence Activity.
J.Med.Chem., 53, 2010
4WE2
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DONOR STRAND COMPLEMENTED FAEG OF F4AB FIMBRIAE
Descriptor:K88 fimbrial protein AB
Authors:Moonens, K., Van den Broeck, I., De Kerpel, M., Deboeck, F., Raymaekers, H., Remaut, H., De Greve, H.
Deposit date:2014-09-09
Release date:2015-02-04
Last modified:2015-04-08
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural and Functional Insight into the Carbohydrate Receptor Binding of F4 Fimbriae-producing Enterotoxigenic Escherichia coli.
J.Biol.Chem., 290, 2015
4WEI
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CRYSTAL STRUCTURE OF THE F4 FIMBRIAL ADHESIN FAEG IN COMPLEX WITH LACTOSE
Descriptor:K88 fimbrial protein AD, ALPHA-D-GLUCOSE, BETA-D-GALACTOSE
Authors:Moonens, K., Van den Broeck, I., De Kerpel, M., Deboeck, F., Raymaekers, H., Remaut, H., De Greve, H.
Deposit date:2014-09-10
Release date:2015-02-04
Last modified:2015-04-08
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural and Functional Insight into the Carbohydrate Receptor Binding of F4 Fimbriae-producing Enterotoxigenic Escherichia coli.
J.Biol.Chem., 290, 2015
4B4P
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CRYSTAL STRUCTURE OF THE LECTIN DOMAIN OF F18 FIMBRIAL ADHESIN FEDF.
Descriptor:F18 FIMBRIAL ADHESIN AC, BROMIDE ION, SULFATE ION
Authors:Moonens, K., Bouckaert, J., Coddens, A., Tran, T., Panjikar, S., De Kerpel, M., Cox, E., Remaut, H., De Greve, H.
Deposit date:2012-07-31
Release date:2012-08-15
Last modified:2012-10-03
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural Insight in Histo-Blood Group Binding by the F18 Fimbrial Adhesin Fedf.
Mol.Microbiol., 86, 2012
4B4Q
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CRYSTAL STRUCTURE OF THE LECTIN DOMAIN OF F18 FIMBRIAL ADHESIN FEDF IN COMPLEX WITH BLOOD GROUP A TYPE 1 HEXASACCHARIDE
Descriptor:F18 FIMBRIAL ADHESIN AC, N-ACETYL-2-DEOXY-2-AMINO-GALACTOSE, BETA-D-GALACTOSE, ...
Authors:Moonens, K., Bouckaert, J., Coddens, A., Tran, T., Panjikar, S., De Kerpel, M., Cox, E., Remaut, H., De Greve, H.
Deposit date:2012-07-31
Release date:2012-08-15
Last modified:2012-10-03
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Insight in Histo-Blood Group Binding by the F18 Fimbrial Adhesin Fedf.
Mol.Microbiol., 86, 2012
4B4R
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CRYSTAL STRUCTURE OF THE LECTIN DOMAIN OF F18 FIMBRIAL ADHESIN FEDF IN COMPLEX WITH BLOOD GROUP B TYPE 1 HEXASACCHARIDE
Descriptor:F18 FIMBRIAL ADHESIN AC, ALPHA D-GALACTOSE, BETA-D-GALACTOSE, ...
Authors:Moonens, K., Bouckaert, J., Coddens, A., Tran, T., Panjikar, S., De Kerpel, M., Cox, E., Remaut, H., De Greve, H.
Deposit date:2012-07-31
Release date:2012-08-15
Last modified:2012-10-03
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural Insight in Histo-Blood Group Binding by the F18 Fimbrial Adhesin Fedf.
Mol.Microbiol., 86, 2012
4WEM
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CO-COMPLEX STRUCTURE OF THE F4 FIMBRIAL ADHESIN FAEG VARIANT AC WITH LLAMA SINGLE DOMAIN ANTIBODY V1
Descriptor:K88 fimbrial protein AC, Anti-F4+ETEC bacteria VHH variable region, PHOSPHATE ION
Authors:Moonens, K., Van den Broeck, I., Pardon, E., De Kerpel, M., Remaut, H., De Greve, H.
Deposit date:2014-09-10
Release date:2015-02-04
Last modified:2015-04-15
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structural insight in the inhibition of adherence of F4 fimbriae producing enterotoxigenic Escherichia coli by llama single domain antibodies.
Vet. Res., 46, 2015
4WEN
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CO-COMPLEX STRUCTURE OF THE F4 FIMBRIAL ADHESIN FAEG VARIANT AC WITH LLAMA SINGLE DOMAIN ANTIBODY V2
Descriptor:K88 fimbrial protein AC, Anti-F4+ETEC bacteria VHH variable region
Authors:Moonens, K., Van den Broeck, I., Pardon, E., De Kerpel, M., Remaut, H., De Greve, H.
Deposit date:2014-09-10
Release date:2015-02-04
Last modified:2015-04-15
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Structural insight in the inhibition of adherence of F4 fimbriae producing enterotoxigenic Escherichia coli by llama single domain antibodies.
Vet. Res., 46, 2015
4WEU
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CO-COMPLEX STRUCTURE OF THE F4 FIMBRIAL ADHESIN FAEG VARIANT AD WITH LLAMA SINGLE DOMAIN ANTIBODY V3
Descriptor:Anti-F4+ETEC bacteria VHH variable region, K88 fimbrial protein AD
Authors:Moonens, K., Van den Broeck, I., Pardon, E., De Kerpel, M., Remaut, H., De Greve, H.
Deposit date:2014-09-11
Release date:2015-02-04
Last modified:2015-04-15
Method:X-RAY DIFFRACTION (2.61 Å)
Cite:Structural insight in the inhibition of adherence of F4 fimbriae producing enterotoxigenic Escherichia coli by llama single domain antibodies.
Vet. Res., 46, 2015
4P2C
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COMPLEX OF SHIGA TOXIN 2E WITH A NEUTRALIZING SINGLE-DOMAIN ANTIBODY
Descriptor:Shiga toxin 2e, subunit A, subunit B, ...
Authors:Lo, A.W.H., Moonens, K., De Kerpel, M., Brys, L., Pardon, E., Remaut, H., De Greve, H.
Deposit date:2014-03-03
Release date:2014-07-30
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2.818 Å)
Cite:The Molecular Mechanism of Shiga Toxin Stx2e Neutralization by a Single-domain Antibody Targeting the Cell Receptor-binding Domain.
J.Biol.Chem., 289, 2014
4W6W
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CO-COMPLEX STRUCTURE OF THE LECTIN DOMAIN OF F18 FIMBRIAL ADHESIN FEDF WITH INHIBITORY NANOBODY NBFEDF6
Descriptor:F18 fimbrial adhesin AC, NbFedF6
Authors:Moonens, K., De Kerpel, M., Annelies, C., Cox, E., Pardon, E., Remaut, H., De Greve, H.
Deposit date:2014-08-21
Release date:2014-12-17
Last modified:2018-02-07
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:Nanobody Mediated Inhibition of Attachment of F18 Fimbriae Expressing Escherichia coli.
Plos One, 9, 2014
4W6X
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CO-COMPLEX STRUCTURE OF THE LECTIN DOMAIN OF F18 FIMBRIAL ADHESIN FEDF WITH INHIBITORY NANOBODY NBFEDF7
Descriptor:F18 fimbrial adhesin AC, Nanobody NbFedF7
Authors:Moonens, K., De Kerpel, M., Coddens, A., Cox, E., Pardon, E., Remaut, H., De Greve, H.
Deposit date:2014-08-21
Release date:2014-12-17
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Nanobody Mediated Inhibition of Attachment of F18 Fimbriae Expressing Escherichia coli.
Plos One, 9, 2014
4W6Y
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CO-COMPLEX STRUCTURE OF THE LECTIN DOMAIN OF F18 FIMBRIAL ADHESIN FEDF WITH INHIBITORY NANOBODY NBFEDF9
Descriptor:F18 fimbrial adhesin AC, Nanobody NbFedF9, SULFATE ION
Authors:Moonens, K., De Kerpel, M., Coddens, A., Cox, E., Pardon, E., Remaut, H., De Greve, H.
Deposit date:2014-08-21
Release date:2014-12-17
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (1.57 Å)
Cite:Nanobody Mediated Inhibition of Attachment of F18 Fimbriae Expressing Escherichia coli.
Plos One, 9, 2014