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1DCT
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BU of 1dct by Molmil
DNA (CYTOSINE-5) METHYLASE FROM HAEIII COVALENTLY BOUND TO DNA
Descriptor: CALCIUM ION, DNA (5'-D(*AP*CP*CP*AP*GP*CP*AP*GP*GP*(C49)P*CP*AP*CP*CP*AP*GP*TP*G)-3'), DNA (5'-D(*TP*CP*AP*CP*TP*GP*GP*TP*GP*GP*(C5M)P*CP*TP*GP*CP*TP*GP*G)-3'), ...
Authors:Reinisch, K.M, Chen, L, Verdine, G.L, Lipscomb, W.N.
Deposit date:1995-05-17
Release date:1995-09-15
Last modified:2019-11-20
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The crystal structure of HaeIII methyltransferase convalently complexed to DNA: an extrahelical cytosine and rearranged base pairing.
Cell(Cambridge,Mass.), 82, 1995
1EJ6
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BU of 1ej6 by Molmil
Reovirus core
Descriptor: LAMBDA1, LAMBDA2, SIGMA2, ...
Authors:Reinisch, K.M, Nibert, M.L, Harrison, S.C.
Deposit date:2000-02-29
Release date:2000-07-12
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Structure of the reovirus core at 3.6 A resolution.
Nature, 404, 2000
2OCY
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BU of 2ocy by Molmil
Complex of the guanine exchange factor Sec2p and the Rab GTPase Sec4p
Descriptor: Rab guanine nucleotide exchange factor SEC2, Ras-related protein SEC4
Authors:Reinisch, K.M, Dong, G.
Deposit date:2006-12-21
Release date:2007-02-27
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:A Catalytic Coiled Coil: Structural Insights into the Activation of the Rab GTPase Sec4p by Sec2p.
Mol.Cell, 25, 2007
2I91
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BU of 2i91 by Molmil
60kDa Ro autoantigen in complex with a fragment of misfolded RNA
Descriptor: 5'-R(*C*GP*GP*UP*AP*GP*GP*CP*UP*UP*UP*UP*CP*AP*A)-3', 5'-R(*GP*CP*CP*UP*AP*CP*CP*C)-3', 60 kDa SS-A/Ro ribonucleoprotein, ...
Authors:Reinisch, K.M, Stein, A.J.
Deposit date:2006-09-04
Release date:2006-10-17
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structural and biochemical basis for misfolded RNA recognition by the Ro autoantigen.
Nat.Struct.Mol.Biol., 13, 2006
3NYB
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BU of 3nyb by Molmil
Structure and function of the polymerase core of TRAMP, a RNA surveillance complex
Descriptor: Poly(A) RNA polymerase protein 2, Protein AIR2, ZINC ION
Authors:Reinisch, K.M, Hamill, S.
Deposit date:2010-07-14
Release date:2010-08-04
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.7007 Å)
Cite:Structure and function of the polymerase core of TRAMP, a RNA surveillance complex.
Proc.Natl.Acad.Sci.USA, 107, 2010
8EDV
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BU of 8edv by Molmil
Mitoguardin homolog (MIGA) delta TM residues 106-496 from Caenorhabditis elegans bound to modelled lipid phosphatidylethanolamine
Descriptor: DI-PALMITOYL-3-SN-PHOSPHATIDYLETHANOLAMINE, MItoGuArdin homolog
Authors:Hong, Z, Adlakha, J, Reinisch, K.M.
Deposit date:2022-09-06
Release date:2022-10-12
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Mitoguardin-2-mediated lipid transfer preserves mitochondrial morphology and lipid droplet formation.
J.Cell Biol., 221, 2022
3TW8
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BU of 3tw8 by Molmil
GEF domain of DENND 1B in complex with Rab GTPase Rab35
Descriptor: DENN domain-containing protein 1B, Ras-related protein Rab-35
Authors:Wu, X.D, Kummel, D, Reinisch, K.M.
Deposit date:2011-09-21
Release date:2011-11-16
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Insights regarding guanine nucleotide exchange from the structure of a DENN-domain protein complexed with its Rab GTPase substrate.
Proc.Natl.Acad.Sci.USA, 108, 2011
7U8T
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BU of 7u8t by Molmil
Vps13 adaptor binding domain in complex with Mcp1 PxP motif peptide
Descriptor: Mcp1 PxP motif,Putative vacuolar protein sorting-associated protein
Authors:Adlakha, J, Reinisch, K.M.
Deposit date:2022-03-09
Release date:2022-03-30
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural and biochemical insights into lipid transport by VPS13 proteins.
J.Cell Biol., 221, 2022
1S29
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BU of 1s29 by Molmil
La autoantigen N-terminal domain
Descriptor: La protein
Authors:Dong, G, Chakshusmathi, G, Wolin, S.L, Reinisch, K.M.
Deposit date:2004-01-08
Release date:2004-03-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structure of the La motif: a winged helix domain mediates RNA binding via a conserved aromatic patch.
Embo J., 23, 2004
5TOD
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BU of 5tod by Molmil
Transmembrane protein 24 SMP domain
Descriptor: Transmembrane protein 24
Authors:Lees, J.A, Reinisch, K.M.
Deposit date:2016-10-17
Release date:2017-03-01
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (2.96 Å)
Cite:Lipid transport by TMEM24 at ER-plasma membrane contacts regulates pulsatile insulin secretion.
Science, 355, 2017
5DSE
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BU of 5dse by Molmil
Crystal Structure of the TTC7B/Hyccin Complex
Descriptor: Hyccin, Tetratricopeptide repeat protein 7B
Authors:Wu, X, Baskin, J.M, Reinisch, K.M, De Camilli, P.
Deposit date:2015-09-17
Release date:2015-12-02
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:The leukodystrophy protein FAM126A (hyccin) regulates PtdIns(4)P synthesis at the plasma membrane.
Nat.Cell Biol., 18, 2016
5CQC
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BU of 5cqc by Molmil
Crystal structure of the legionella pneumophila effector protein RavZ
Descriptor: BARIUM ION, putative RavZ protein
Authors:Horenkamp, F.A, Reinisch, K.M.
Deposit date:2015-07-21
Release date:2015-09-09
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.985 Å)
Cite:The Legionella Anti-autophagy Effector RavZ Targets the Autophagosome via PI3P- and Curvature-Sensing Motifs.
Dev.Cell, 34, 2015
2B1E
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BU of 2b1e by Molmil
The structures of exocyst subunit Exo70p and the Exo84p C-terminal domains reveal a common motif
Descriptor: Exocyst complex component EXO70
Authors:Dong, G, Hutagalung, A.H, Fu, C, Novick, P, Reinisch, K.M.
Deposit date:2005-09-15
Release date:2005-11-01
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:The structures of exocyst subunit Exo70p and the Exo84p C-terminal domains reveal a common motif
Nat.Struct.Mol.Biol., 12, 2005
2AT2
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BU of 2at2 by Molmil
MOLECULAR STRUCTURE OF BACILLUS SUBTILIS ASPARTATE TRANSCARBAMOYLASE AT 3.0 ANGSTROMS RESOLUTION
Descriptor: ASPARTATE CARBAMOYLTRANSFERASE
Authors:Stevens, R.C, Reinisch, K.M, Lipscomb, W.N.
Deposit date:1992-07-20
Release date:1994-01-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3 Å)
Cite:Molecular structure of Bacillus subtilis aspartate transcarbamoylase at 3.0 A resolution.
Proc.Natl.Acad.Sci.USA, 88, 1991
2D2S
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BU of 2d2s by Molmil
Crystal Structure of the Exo84p C-terminal Domains
Descriptor: Exocyst complex component EXO84
Authors:Dong, G, Hutagalung, A.H, Fu, C, Novick, P, Reinisch, K.M.
Deposit date:2005-09-16
Release date:2005-11-01
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:The structures of exocyst subunit Exo70p and the Exo84p C-terminal domains reveal a common motif
Nat.Struct.Mol.Biol., 12, 2005
1YVP
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BU of 1yvp by Molmil
Ro autoantigen complexed with RNAs
Descriptor: 60-kDa SS-A/Ro ribonucleoprotein, ACETATE ION, MAGNESIUM ION, ...
Authors:Stein, A.J, Fuchs, G, Fu, C, Wolin, S.L, Reinisch, K.M.
Deposit date:2005-02-16
Release date:2005-06-07
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Insights into RNA Quality Control: The Ro Autoantigen Binds Misfolded RNAs via Its Central Cavity
Cell(Cambridge,Mass.), 121, 2005
1YVR
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BU of 1yvr by Molmil
Ro autoantigen
Descriptor: 60-kDa SS-A/Ro ribonucleoprotein
Authors:Stein, A.J, Fuchs, G, Fu, C, Wolin, S.L, Reinisch, K.M.
Deposit date:2005-02-16
Release date:2005-06-07
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural Insights into RNA Quality Control: The Ro Autoantigen Binds Misfolded RNAs via Its Central Cavity
Cell(Cambridge,Mass.), 121, 2005
3CUE
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BU of 3cue by Molmil
Crystal structure of a TRAPP subassembly activating the Rab Ypt1p
Descriptor: GTP-binding protein YPT1, PALMITIC ACID, Transport protein particle 18 kDa subunit, ...
Authors:Cai, Y, Reinisch, K.M.
Deposit date:2008-04-16
Release date:2008-07-08
Last modified:2012-03-21
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:The structural basis for activation of the Rab Ypt1p by the TRAPP membrane-tethering complexes.
Cell(Cambridge,Mass.), 133, 2008
3F8U
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BU of 3f8u by Molmil
Tapasin/ERp57 heterodimer
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Protein disulfide-isomerase A3ERp57, Tapasin
Authors:Dong, G, Reinisch, K.M.
Deposit date:2008-11-13
Release date:2009-01-13
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Insights into MHC class I peptide loading from the structure of the tapasin-ERp57 thiol oxidoreductase heterodimer.
Immunity, 30, 2009
6BQ1
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BU of 6bq1 by Molmil
Human PI4KIIIa lipid kinase complex
Descriptor: 5-{2-amino-1-[4-(morpholin-4-yl)phenyl]-1H-benzimidazol-6-yl}-N-(2-fluorophenyl)-2-methoxypyridine-3-sulfonamide, Phosphatidylinositol 4-kinase III alpha (PI4KA), Protein FAM126A, ...
Authors:Lees, J.A, Zhang, Y, Oh, M, Schauder, C.M, Yu, X, Baskin, J, Dobbs, K, Notarangelo, L.D, Camilli, P.D, Walz, T, Reinisch, K.M.
Deposit date:2017-11-27
Release date:2017-12-13
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Architecture of the human PI4KIII alpha lipid kinase complex.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
6CAY
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BU of 6cay by Molmil
Crystal structure of the first StART-like domain of Ysp2p/Lam2p in its apo and ergosterol-bound state.
Descriptor: ERGOSTEROL, Sterol-binding protein
Authors:Horenkamp, F.A, Valverde, D.P, Reinisch, K.M.
Deposit date:2018-02-01
Release date:2018-02-28
Last modified:2020-01-01
Method:X-RAY DIFFRACTION (2 Å)
Cite:Molecular basis for sterol transport by StART-like lipid transfer domains.
EMBO J., 37, 2018
6CBC
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BU of 6cbc by Molmil
Crystal structure of an N-terminal fragment of Vps13.
Descriptor: Vacuolar protein sorting-associated protein
Authors:Kumar, N, Horenkamp, F.A, Reinisch, K.M.
Deposit date:2018-02-02
Release date:2018-08-08
Last modified:2020-01-01
Method:X-RAY DIFFRACTION (3 Å)
Cite:VPS13A and VPS13C are lipid transport proteins differentially localized at ER contact sites.
J. Cell Biol., 217, 2018
4N5C
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BU of 4n5c by Molmil
Crystal structure of Ypp1
Descriptor: Cargo-transport protein YPP1
Authors:Wu, X, Chi, R.J, Baskin, J.M, Lucast, L, Burd, C.G, De Camilli, P, Reinisch, K.M.
Deposit date:2013-10-09
Release date:2014-01-22
Last modified:2014-03-19
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:Structural insights into assembly and regulation of the plasma membrane phosphatidylinositol 4-kinase complex.
Dev.Cell, 28, 2014
4N5A
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BU of 4n5a by Molmil
Crystal structure of Efr3
Descriptor: Protein EFR3
Authors:Wu, X, Chi, R.J, Baskin, J.M, Lucast, L, Burd, C.G, De Camilli, P, Reinisch, K.M.
Deposit date:2013-10-09
Release date:2014-01-22
Last modified:2014-03-19
Method:X-RAY DIFFRACTION (3.204 Å)
Cite:Structural insights into assembly and regulation of the plasma membrane phosphatidylinositol 4-kinase complex.
Dev.Cell, 28, 2014
4P42
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BU of 4p42 by Molmil
Extended-Synaptotagmin 2, SMP - C2A - C2B Domains
Descriptor: 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, 2-(2-{2-[2-(2-{2-[2-(2-{2-[4-(1,1,3,3-TETRAMETHYL-BUTYL)-PHENOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOX Y}-ETHOXY)-ETHANOL, Extended synaptotagmin-2
Authors:Schauder, C.M, Wu, X, Reinisch, K.M.
Deposit date:2014-03-10
Release date:2014-05-14
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.44 Å)
Cite:Structure of a lipid-bound extended synaptotagmin indicates a role in lipid transfer.
Nature, 510, 2014

 

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