Author results

3NZJ
  • Download 3nzj
  • View 3nzj
Molmil generated image of 3nzj
CRYSTAL STRUCTURE OF YEAST 20S PROTEASOME IN COMPLEX WITH LIGAND 2A
Descriptor:Proteasome component Y7, Proteasome component Y13, Proteasome component PRE6, ...
Authors:Groll, M., Gallastegui, N., Marechal, X., Le Ravalec, V., Basse, N., Richy, N., Genin, E., Huber, R., Moroder, M., Vidal, V., Reboud-Ravaux, M.
Deposit date:2010-07-16
Release date:2011-02-16
Last modified:2012-12-12
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:20S proteasome inhibition: designing noncovalent linear peptide mimics of the natural product TMC-95A.
Chemmedchem, 5, 2010
3NZW
  • Download 3nzw
  • View 3nzw
Molmil generated image of 3nzw
CRYSTAL STRUCTURE OF THE YEAST 20S PROTEASOME IN COMPLEX WITH 2B
Descriptor:Proteasome component Y7, Proteasome component Y13, Proteasome component PRE6, ...
Authors:Groll, M., Gallastegui, N., Marechal, X., Le Ravalec, V., Basse, N., Richy, N., Genin, E., Huber, R., Moroder, M., Vidal, V., Reboud-Ravaux, M.
Deposit date:2010-07-17
Release date:2011-02-16
Last modified:2012-12-12
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:20S proteasome inhibition: designing noncovalent linear peptide mimics of the natural product TMC-95A.
Chemmedchem, 5, 2010
3NZX
  • Download 3nzx
  • View 3nzx
Molmil generated image of 3nzx
CRYSTAL STRUCTURE OF THE YEAST 20S PROTEASOME IN COMPLEX WITH LIGAND 2C
Descriptor:Proteasome component Y7, Proteasome component Y13, Proteasome component PRE6, ...
Authors:Groll, M., Gallastegui, N., Marechal, X., Le Ravalec, V., Basse, N., Richy, N., Genin, E., Huber, R., Moroder, M., Vidal, V., Reboud-Ravaux, M.
Deposit date:2010-07-17
Release date:2011-02-16
Last modified:2012-12-12
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:20S proteasome inhibition: designing noncovalent linear peptide mimics of the natural product TMC-95A.
Chemmedchem, 5, 2010
4JSQ
  • Download 4jsq
  • View 4jsq
Molmil generated image of 4jsq
YEAST 20S PROTEASOME IN COMPLEX WITH THE DIMERIZED LINEAR MIMETIC OF TMC-95A - YCP:4E
Descriptor:Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, Proteasome subunit alpha type-4, ...
Authors:Desvergne, A., Genin, E., Marechal, X., Gallastegui, N., Dufau, L., Richy, N., Groll, M., Vidal, J., Reboud-Ravaux, M.
Deposit date:2013-03-22
Release date:2013-05-01
Last modified:2014-04-23
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Dimerized linear mimics of a natural cyclopeptide (TMC-95A) are potent noncovalent inhibitors of the eukaryotic 20S proteasome
J.Med.Chem., 56, 2013
4JSU
  • Download 4jsu
  • View 4jsu
Molmil generated image of 4jsu
YEAST 20S PROTEASOME IN COMPLEX WITH THE DIMERIZED LINEAR MIMETIC OF TMC-95A - YCP:3A
Descriptor:Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, Proteasome subunit alpha type-4, ...
Authors:Desvergne, A., Genin, E., Marechal, X., Gallastegui, N., Dufau, L., Richy, N., Groll, M., Vidal, J., Reboud-Ravaux, M.
Deposit date:2013-03-22
Release date:2013-05-01
Last modified:2014-04-23
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Dimerized linear mimics of a natural cyclopeptide (TMC-95A) are potent noncovalent inhibitors of the eukaryotic 20S proteasome
J.Med.Chem., 56, 2013
4JT0
  • Download 4jt0
  • View 4jt0
Molmil generated image of 4jt0
YEAST 20S PROTEASOME IN COMPLEX WITH THE DIMERIZED LINEAR MIMETIC OF TMC-95A - YCP:4A
Descriptor:Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, Proteasome subunit alpha type-4, ...
Authors:Desvergne, A., Genin, E., Marechal, X., Gallastegui, N., Dufau, L., Richy, N., Groll, M., Vidal, J., Reboud-Ravaux, M.
Deposit date:2013-03-22
Release date:2013-05-01
Last modified:2013-06-05
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Dimerized Linear Mimics of a Natural Cyclopeptide (TMC-95A) Are Potent Noncovalent Inhibitors of the Eukaryotic 20S Proteasome
J.Med.Chem., 2013
5BOU
  • Download 5bou
  • View 5bou
Molmil generated image of 5bou
YEAST 20S PROTEASOME IN COMPLEX WITH A BETA1 / BETA2 SPECIFIC NON-PEPTIDIC SULFONAMIDE LIGAND
Descriptor:Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, Proteasome subunit alpha type-4, ...
Authors:Beck, P., Groll, M.
Deposit date:2015-05-27
Release date:2015-08-19
Last modified:2015-09-16
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Identification of a beta 1/ beta 2-Specific Sulfonamide Proteasome Ligand by Crystallographic Screening.
Angew.Chem.Int.Ed.Engl., 54, 2015
6SHH
  • Download 6shh
  • View 6shh
Molmil generated image of 6shh
HUMAN KALLIKREIN 7 WITH AROMATIC COUMARINIC ESTER COMPOUND 1 COVALENTLY BOUND TO H57
Descriptor:Kallikrein-7, TRIETHYLENE GLYCOL, SULFATE ION, ...
Authors:Hanke, S., Straeter, N.
Deposit date:2019-08-06
Release date:2020-05-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural studies on the inhibitory binding mode of aromatic coumarinic esters to human kallikrein-related peptidase 7.
J.Med.Chem., 2020
6SHI
  • Download 6shi
  • View 6shi
Molmil generated image of 6shi
HUMAN KALLIKREIN 7 WITH AROMATIC COUMARINIC ESTER COMPOUND 2 COVALENTLY BOUND TO H57
Descriptor:Kallikrein-7, TRIETHYLENE GLYCOL, 6-methyl-2-oxidanylidene-chromene-3-carboxylic acid, ...
Authors:Hanke, S., Straeter, N.
Deposit date:2019-08-06
Release date:2020-05-20
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural studies on the inhibitory binding mode of aromatic coumarinic esters to human kallikrein-related peptidase 7.
J.Med.Chem., 2020
6SJU
  • Download 6sju
  • View 6sju
Molmil generated image of 6sju
HUMAN KALLIKREIN 7 WITH AROMATIC COUMARINIC ESTER COMPOUND 3 COVALENTLY BOUND TO H57
Descriptor:Kallikrein-7, TRIETHYLENE GLYCOL, SULFATE ION, ...
Authors:Hanke, S., Straeter, N.
Deposit date:2019-08-13
Release date:2020-05-20
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Structural studies on the inhibitory binding mode of aromatic coumarinic esters to human kallikrein-related peptidase 7.
J.Med.Chem., 2020
6Y4S
  • Download 6y4s
  • View 6y4s
Molmil generated image of 6y4s
HUMAN KALLIKREIN-RELATED PEPTIDASE 7 (KLK7) IN THE UNLIGANDED STATE
Descriptor:Kallikrein-7, TRIETHYLENE GLYCOL, SULFATE ION
Authors:Hanke, S., Strater, N.
Deposit date:2020-02-23
Release date:2020-05-20
Method:X-RAY DIFFRACTION (2.23 Å)
Cite:Structural studies on the inhibitory binding mode of aromatic coumarinic esters to human kallikrein-related peptidase 7.
J.Med.Chem., 2020