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6GDH
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HOLLIDAY JUNCTIONS FORMED FROM TELOMERIC DNA
Descriptor:DNA (5'-D(*CP*TP*AP*AP*CP*CP*CP*TP*AP*A)-3'), DNA (5'-D(*TP*TP*AP*GP*GP*GP*TP*TP*AP*G)-3')
Authors:Parkinson, G.N., Haider, S., Li, P., Khiali, S., Munnur, D., Ramanathan, A.
Deposit date:2018-04-23
Release date:2018-11-07
Last modified:2018-11-21
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Holliday Junctions Formed from Human Telomeric DNA.
J. Am. Chem. Soc., 140, 2018
6GDN
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HOLLIDAY JUNCTIONS FORMED FROM TELOMERIC DNA
Descriptor:Telomere DNA (42-MER), MAGNESIUM ION
Authors:Parkinson, G.N., Haider, S., Li, P., Khiali, S., Munnur, D., Ramanathan, A.
Deposit date:2018-04-24
Release date:2018-11-07
Last modified:2018-11-21
Method:X-RAY DIFFRACTION (3 Å)
Cite:Holliday Junctions Formed from Human Telomeric DNA.
J. Am. Chem. Soc., 140, 2018
6GDS
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HOLLIDAY JUNCTIONS FORMED FROM TELOMERIC DNA
Descriptor:Telomeric DNA (5' CTAACCCTAA) 10mer, Telomeric DNA (5'-TTAGGGTTAG)-3') 10mer
Authors:Parkinson, G.N., Haider, S., Li, P., Khiali, S., Munnur, D., Ramanathan, A.
Deposit date:2018-04-24
Release date:2018-11-07
Last modified:2018-11-21
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Holliday Junctions Formed from Human Telomeric DNA.
J. Am. Chem. Soc., 140, 2018
4JOA
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CRYSTAL STRUCTURE OF HUMAN ANAPLASTIC LYMPHOMA KINASE IN COMPLEX WITH 7-AZAINDOLE BASED INHIBITOR
Descriptor:ALK tyrosine kinase receptor, 3-[1-(2,5-difluorobenzyl)-1H-pyrazol-4-yl]-5-(1-methyl-1H-pyrazol-4-yl)-1H-pyrrolo[2,3-b]pyridine
Authors:Hosahalli, S., Krishnamurthy, N.R., Lakshminarasimhan, A.
Deposit date:2013-03-18
Release date:2013-07-17
Last modified:2014-04-23
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Discovery of 7-azaindole based anaplastic lymphoma kinase (ALK) inhibitors: wild type and mutant (L1196M) active compounds with unique binding mode
Bioorg.Med.Chem.Lett., 23, 2013
4QL8
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CRYSTAL STRUCTURE OF ANDROGEN RECEPTOR IN COMPLEX WITH THE LIGAND
Descriptor:Androgen receptor, 2-chloro-4-[(3S,3aS,4S)-4-hydroxy-3-methoxy-3a,4,5,6-tetrahydro-3H-pyrrolo[1,2-b]pyrazol-2-yl]-3-methylbenzonitrile
Authors:Krishnamurthy, N., Sangeetha, R., Ghadiyaram, C., Sasmal, S., Subramanya, H.S.
Deposit date:2014-06-11
Release date:2015-06-17
Last modified:2016-03-23
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:3-alkoxy-pyrrolo[1,2-b]pyrazolines as selective androgen receptor modulators with ideal physicochemical properties for transdermal administration
J.Med.Chem., 57, 2014
5E3H
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STRUCTURAL BASIS FOR RNA RECOGNITION AND ACTIVATION OF RIG-I
Descriptor:Probable ATP-dependent RNA helicase DDX58, RNA (5'-R(*CP*GP*AP*CP*GP*CP*UP*AP*GP*CP*GP*U)-3'), ZINC ION, ...
Authors:Jiang, F., Miller, M.T., Marcotrigiano, J.
Deposit date:2015-10-02
Release date:2015-11-18
Last modified:2017-08-09
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural basis of RNA recognition and activation by innate immune receptor RIG-I.
Nature, 479, 2011
5EAJ
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CRYSTAL STRUCTURE OF DHFR IN 0% ISOPROPANOL
Descriptor:Dihydrofolate reductase, FOLIC ACID, CALCIUM ION, ...
Authors:Cuneo, M.J., Agarwal, P.K.
Deposit date:2015-10-16
Release date:2016-09-21
Last modified:2018-09-12
Method:X-RAY DIFFRACTION (1.701 Å)
Cite:Modulating Enzyme Activity by Altering Protein Dynamics with Solvent.
Biochemistry, 57, 2018
5EFM
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BECLIN 1 FLEXIBLE-HELICAL DOMIAN (FHD) (141-171)
Descriptor:Beclin-1, SULFATE ION
Authors:Sinha, S., Mei, Y.
Deposit date:2015-10-23
Release date:2016-07-20
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Conformational Flexibility Enables the Function of a BECN1 Region Essential for Starvation-Mediated Autophagy.
Biochemistry, 55, 2016
5F98
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CRYSTAL STRUCTURE OF RIG-I IN COMPLEX WITH CAP-0 RNA
Descriptor:Probable ATP-dependent RNA helicase DDX58, RNA (5'-R(P*GP*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP*AP*UP*AP*UP*UP*AP*UP*AP*UP*UP*C)-3'), ZINC ION, ...
Authors:Wang, C., Marcotrigiano, J., Miller, M., Jiang, F.
Deposit date:2015-12-09
Release date:2016-01-13
Last modified:2016-01-27
Method:X-RAY DIFFRACTION (3.28 Å)
Cite:Structural basis for m7G recognition and 2'-O-methyl discrimination in capped RNAs by the innate immune receptor RIG-I.
Proc.Natl.Acad.Sci.USA, 113, 2016
5F9F
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CRYSTAL STRUCTURE OF RIG-I HELICASE-RD IN COMPLEX WITH 24-MER BLUNT-END HAIRPIN RNA
Descriptor:Probable ATP-dependent RNA helicase DDX58, RNA (5'-R(*GP*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP*AP*UP*AP*UP*UP*AP*UP*AP*UP*UP*C)-3'), ZINC ION, ...
Authors:Wang, C., Marcotrigiano, J., Miller, M.T., Jiang, F.
Deposit date:2015-12-09
Release date:2016-01-13
Last modified:2016-01-27
Method:X-RAY DIFFRACTION (2.601 Å)
Cite:Structural basis for m7G recognition and 2'-O-methyl discrimination in capped RNAs by the innate immune receptor RIG-I.
Proc.Natl.Acad.Sci.USA, 113, 2016
5F9H
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CRYSTAL STRUCTURE OF RIG-I HELICASE-RD IN COMPLEX WITH 24-MER 5' TRIPHOSPHATE HAIRPIN RNA
Descriptor:Probable ATP-dependent RNA helicase DDX58, RNA (5'-R(P*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP*AP*UP*AP*UP*UP*AP*UP*AP*UP*UP*C)-3'), ZINC ION, ...
Authors:Wang, C., Marcotrigiano, J., Miller, M., Jiang, F.
Deposit date:2015-12-09
Release date:2016-01-13
Last modified:2016-04-06
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural basis for m7G recognition and 2'-O-methyl discrimination in capped RNAs by the innate immune receptor RIG-I.
Proc.Natl.Acad.Sci.USA, 113, 2016
5UJX
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CRYSTAL STRUCTURE OF DHFR IN 20% ISOPROPANOL
Descriptor:Dihydrofolate reductase, FOLIC ACID, ISOPROPYL ALCOHOL, ...
Authors:Cuneo, M.J., Agarwal, P.K.
Deposit date:2017-01-19
Release date:2017-12-27
Last modified:2018-09-12
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Modulating Enzyme Activity by Altering Protein Dynamics with Solvent.
Biochemistry, 57, 2018