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1LW6
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BU of 1lw6 by Molmil
Crystal Structure of the Complex of Subtilisin BPN' with Chymotrypsin Inhibitor 2 at 1.5 Angstrom Resolution
Descriptor: CALCIUM ION, SUBTILISIN BPN', SUBTILISIN-CHYMOTRYPSIN INHIBITOR-2A, ...
Authors:Radisky, E.S, Koshland JR, D.E.
Deposit date:2002-05-30
Release date:2002-08-21
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:A clogged gutter mechanism for protease inhibitors.
Proc.Natl.Acad.Sci.USA, 99, 2002
1TM7
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BU of 1tm7 by Molmil
crystal structure of the complex of subtilisin BPN' with chymotrypsin inhibitor 2 M59Y mutant
Descriptor: CALCIUM ION, CITRIC ACID, PENTAETHYLENE GLYCOL, ...
Authors:Radisky, E.S, Kwan, G, Karen Lu, C.J, Koshland Jr, D.E.
Deposit date:2004-06-10
Release date:2004-11-09
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.59 Å)
Cite:Binding, Proteolytic, and Crystallographic Analyses of Mutations at the Protease-Inhibitor Interface of the Subtilisin BPN'/Chymotrypsin Inhibitor 2 Complex(,).
Biochemistry, 43, 2004
1TM4
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BU of 1tm4 by Molmil
crystal structure of the complex of subtilsin BPN'with chymotrypsin inhibitor 2 M59G mutant
Descriptor: CALCIUM ION, CITRIC ACID, PENTAETHYLENE GLYCOL, ...
Authors:Radisky, E.S, Kwan, G, Karen Lu, C.J, Koshland Jr, D.E.
Deposit date:2004-06-10
Release date:2004-11-09
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Binding, Proteolytic, and Crystallographic Analyses of Mutations at the Protease-Inhibitor Interface of the Subtilisin BPN'/Chymotrypsin Inhibitor 2 Complex(,).
Biochemistry, 43, 2004
1TMG
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BU of 1tmg by Molmil
crystal structure of the complex of subtilisin BPN' with chymotrypsin inhibitor 2 M59F mutant
Descriptor: CALCIUM ION, CITRIC ACID, PENTAETHYLENE GLYCOL, ...
Authors:Radisky, E.S, Kwan, G, Karen Lu, C.J, Koshland Jr, D.E.
Deposit date:2004-06-10
Release date:2004-11-09
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:Binding, Proteolytic, and Crystallographic Analyses of Mutations at the Protease-Inhibitor Interface of the Subtilisin BPN'/Chymotrypsin Inhibitor 2 Complex(,).
Biochemistry, 43, 2004
1TM1
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BU of 1tm1 by Molmil
CRYSTAL STRUCTURE OF THE COMPLEX OF SUBTILISIN BPN' WITH CHYMOTRYPSIN INHIBITOR 2
Descriptor: CALCIUM ION, CITRIC ACID, PENTAETHYLENE GLYCOL, ...
Authors:Radisky, E.S, Kwan, G, Karen Lu, C.J, Koshland Jr, D.E.
Deposit date:2004-06-10
Release date:2004-11-09
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Binding, Proteolytic, and Crystallographic Analyses of Mutations at the Protease-Inhibitor Interface of the Subtilisin BPN'/Chymotrypsin Inhibitor 2 Complex(,).
Biochemistry, 43, 2004
1TM5
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BU of 1tm5 by Molmil
crystal structure of the complex of subtilisin BPN' with chymotrypsin inhibitor 2 M59A mutant
Descriptor: CALCIUM ION, CITRIC ACID, PENTAETHYLENE GLYCOL, ...
Authors:Radisky, E.S, Kwan, G, Karen Lu, C.J, Koshland Jr, D.E.
Deposit date:2004-06-10
Release date:2004-11-09
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Binding, Proteolytic, and Crystallographic Analyses of Mutations at the Protease-Inhibitor Interface of the Subtilisin BPN'/Chymotrypsin Inhibitor 2 Complex(,).
Biochemistry, 43, 2004
1TM3
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BU of 1tm3 by Molmil
crystal structure of the complex of subtilisin BPN' with chymotrypsin inhibitor 2 M59k mutant
Descriptor: CALCIUM ION, CITRIC ACID, PENTAETHYLENE GLYCOL, ...
Authors:Radisky, E.S, Kwan, G, Karen Lu, C.J, Koshland Jr, D.E.
Deposit date:2004-06-10
Release date:2004-11-09
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.57 Å)
Cite:Binding, Proteolytic, and Crystallographic Analyses of Mutations at the Protease-Inhibitor Interface of the Subtilisin BPN'/Chymotrypsin Inhibitor 2 Complex(,).
Biochemistry, 43, 2004
1TO1
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BU of 1to1 by Molmil
crystal structure of the complex of subtilisin BPN' with chymotrypsin inhibitor 2 Y61A mutant
Descriptor: CALCIUM ION, CITRIC ACID, PENTAETHYLENE GLYCOL, ...
Authors:Radisky, E.S, Kwan, G, Karen Lu, C.J, Koshland Jr, D.E.
Deposit date:2004-06-11
Release date:2004-11-09
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:Binding, Proteolytic, and Crystallographic Analyses of Mutations at the Protease-Inhibitor Interface of the Subtilisin BPN'/Chymotrypsin Inhibitor 2 Complex(,).
Biochemistry, 43, 2004
1TO2
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BU of 1to2 by Molmil
crystal structure of the complex of subtilisin BPN' with chymotrypsin inhibitor 2 M59K, in pH 9 cryosoak
Descriptor: CALCIUM ION, CITRIC ACID, POLYETHYLENE GLYCOL (N=34), ...
Authors:Radisky, E.S, Kwan, G, Karen Lu, C.J, Koshland Jr, D.E.
Deposit date:2004-06-11
Release date:2004-11-09
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Binding, Proteolytic, and Crystallographic Analyses of Mutations at the Protease-Inhibitor Interface of the Subtilisin BPN'/Chymotrypsin Inhibitor 2 Complex(,).
Biochemistry, 43, 2004
1Y3C
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BU of 1y3c by Molmil
Crystal structure of the complex of subtilisin BPN' with chymotrypsin inhibitor 2 R62A mutant
Descriptor: CALCIUM ION, CITRIC ACID, POLYETHYLENE GLYCOL (N=34), ...
Authors:Radisky, E.S, Lu, C.J, Kwan, G, Koshland Jr, D.E.
Deposit date:2004-11-24
Release date:2005-05-17
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:Role of the intramolecular hydrogen bond network in the inhibitory power of chymotrypsin inhibitor 2
Biochemistry, 44, 2005
1Y3B
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BU of 1y3b by Molmil
Crystal structure of the complex of subtilisin BPN' with chymotrypsin inhibitor 2 E60S mutant
Descriptor: CALCIUM ION, CITRIC ACID, POLYETHYLENE GLYCOL (N=34), ...
Authors:Radisky, E.S, Lu, C.J, Kwan, G, Koshland Jr, D.E.
Deposit date:2004-11-24
Release date:2005-05-17
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Role of the intramolecular hydrogen bond network in the inhibitory power of chymotrypsin inhibitor 2
Biochemistry, 44, 2005
1Y48
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BU of 1y48 by Molmil
Crystal structure of the complex of subtilisin BPN' with chymotrypsin inhibitor 2 R65A mutant
Descriptor: CALCIUM ION, CITRIC ACID, POLYETHYLENE GLYCOL (N=34), ...
Authors:Radisky, E.S, Lu, C.J, Kwan, G, Koshland Jr, D.E.
Deposit date:2004-11-30
Release date:2005-05-17
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:Role of the intramolecular hydrogen bond network in the inhibitory power of chymotrypsin inhibitor 2
Biochemistry, 44, 2005
1Y33
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BU of 1y33 by Molmil
Crystal structure of the complex of subtilisin BPN' with chymotrypsin inhibitor 2 T58P mutant
Descriptor: CALCIUM ION, CITRIC ACID, POLYETHYLENE GLYCOL (N=34), ...
Authors:Radisky, E.S, Lu, C.J, Kwan, G, Koshland Jr, D.E.
Deposit date:2004-11-23
Release date:2005-05-17
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Role of the intramolecular hydrogen bond network in the inhibitory power of chymotrypsin inhibitor 2
Biochemistry, 44, 2005
1Y34
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BU of 1y34 by Molmil
Crystal structure of the complex of subtilisin BPN' with chymotrypsin inhibitor 2 E60A mutant
Descriptor: CALCIUM ION, CITRIC ACID, POLYETHYLENE GLYCOL (N=34), ...
Authors:Radisky, E.S, Lu, C.J, Kwan, G, Koshland Jr, D.E.
Deposit date:2004-11-23
Release date:2005-05-17
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Role of the intramolecular hydrogen bond network in the inhibitory power of chymotrypsin inhibitor 2
Biochemistry, 44, 2005
1Y4A
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BU of 1y4a by Molmil
Crystal structure of the complex of subtilisin BPN' with chymotrypsin inhibitor 2 M59R/E60S mutant
Descriptor: CALCIUM ION, CITRIC ACID, POLYETHYLENE GLYCOL (N=34), ...
Authors:Radisky, E.S, Lu, C.J, Kwan, G, Koshland Jr, D.E.
Deposit date:2004-11-30
Release date:2005-05-17
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Role of the intramolecular hydrogen bond network in the inhibitory power of chymotrypsin inhibitor 2
Biochemistry, 44, 2005
1Y1K
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BU of 1y1k by Molmil
Crystal structure of the complex of subtilisin BPN' with chymotrypsin inhibitor 2 T58A mutant
Descriptor: CALCIUM ION, CITRIC ACID, POLYETHYLENE GLYCOL (N=34), ...
Authors:Radisky, E.S, Lu, C.J, Kwan, G, Koshland Jr, D.E.
Deposit date:2004-11-18
Release date:2005-05-17
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.56 Å)
Cite:Role of the intramolecular hydrogen bond network in the inhibitory power of chymotrypsin inhibitor 2
Biochemistry, 44, 2005
1Y3F
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BU of 1y3f by Molmil
Crystal structure of the complex of subtilisin BPN' with chymotrypsin inhibitor 2 F69A mutant
Descriptor: CALCIUM ION, CITRIC ACID, POLYETHYLENE GLYCOL (N=34), ...
Authors:Radisky, E.S, Lu, C.J, Kwan, G, Koshland Jr, D.E.
Deposit date:2004-11-24
Release date:2005-05-17
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:Role of the intramolecular hydrogen bond network in the inhibitory power of chymotrypsin inhibitor 2
Biochemistry, 44, 2005
1Y3D
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BU of 1y3d by Molmil
Crystal structure of the complex of subtilisin BPN' with chymotrypsin inhibitor 2 R67A mutant
Descriptor: CALCIUM ION, CITRIC ACID, POLYETHYLENE GLYCOL (N=34), ...
Authors:Radisky, E.S, Lu, C.J, Kwan, G, Koshland Jr, D.E.
Deposit date:2004-11-24
Release date:2005-05-17
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Role of the intramolecular hydrogen bond network in the inhibitory power of chymotrypsin inhibitor 2
Biochemistry, 44, 2005
1Y4D
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BU of 1y4d by Molmil
Crystal structure of the complex of subtilisin BPN' with chymotrypsin inhibitor 2 M59R/E60S mutant
Descriptor: CALCIUM ION, SODIUM ION, chymotrypsin inhibitor 2, ...
Authors:Radisky, E.S, Lu, C.J, Kwan, G, Koshland Jr, D.E.
Deposit date:2004-11-30
Release date:2005-05-17
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2 Å)
Cite:Role of the intramolecular hydrogen bond network in the inhibitory power of chymotrypsin inhibitor 2
Biochemistry, 44, 2005
2AGG
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BU of 2agg by Molmil
succinyl-AAPK-trypsin acyl-enzyme at 1.28 A resolution
Descriptor: CALCIUM ION, SULFATE ION, beta-trypsin, ...
Authors:Radisky, E.S, Lee, J.M, Lu, C.J, Koshland Jr, D.E.
Deposit date:2005-07-26
Release date:2006-05-16
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.28 Å)
Cite:Insights into the serine protease mechanism from atomic resolution structures of trypsin reaction intermediates
Proc.Natl.Acad.Sci.USA, 103, 2006
2AGI
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BU of 2agi by Molmil
The leupeptin-trypsin covalent complex at 1.14 A resolution
Descriptor: CALCIUM ION, SULFATE ION, beta-trypsin, ...
Authors:Radisky, E.S, Lee, J.M, Lu, C.J, Koshland Jr, D.E.
Deposit date:2005-07-26
Release date:2006-05-16
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.14 Å)
Cite:Insights into the serine protease mechanism from atomic resolution structures of trypsin reaction intermediates
Proc.Natl.Acad.Sci.USA, 103, 2006
2AGE
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BU of 2age by Molmil
Succinyl-AAPR-trypsin acyl-enzyme at 1.15 A resolution
Descriptor: CALCIUM ION, beta-trypsin, succinyl-Ala-Ala-Pro-Arg
Authors:Radisky, E.S, Lee, J.M, Lu, C.J, Koshland Jr, D.E.
Deposit date:2005-07-26
Release date:2006-05-16
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.15 Å)
Cite:Insights into the serine protease mechanism from atomic resolution structures of trypsin reaction intermediates
Proc.Natl.Acad.Sci.USA, 103, 2006
2AH4
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BU of 2ah4 by Molmil
guanidinobenzoyl-trypsin acyl-enzyme at 1.13 A resolution
Descriptor: 4-carbamimidamidobenzoic acid, CALCIUM ION, SULFATE ION, ...
Authors:Radisky, E.S, Lee, J.M, Lu, C.J, Koshland Jr, D.E.
Deposit date:2005-07-26
Release date:2006-05-16
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.13 Å)
Cite:Insights into the serine protease mechanism from atomic resolution structures of trypsin reaction intermediates
Proc.Natl.Acad.Sci.USA, 103, 2006
5C67
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BU of 5c67 by Molmil
Human Mesotrypsin in complex with amyloid precursor protein inhibitor variant APPI-M17G/I18F/F34V
Descriptor: Amyloid beta A4 protein, Trypsin-3
Authors:Kayode, O, Sankaran, B, Radisky, E.S.
Deposit date:2015-06-22
Release date:2016-05-04
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Combinatorial protein engineering of proteolytically resistant mesotrypsin inhibitors as candidates for cancer therapy.
Biochem.J., 473, 2016
3V96
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BU of 3v96 by Molmil
Complex of matrix metalloproteinase-10 catalytic domain (MMP-10cd) with tissue inhibitor of metalloproteinases-1 (TIMP-1)
Descriptor: CALCIUM ION, Metalloproteinase inhibitor 1, PHOSPHATE ION, ...
Authors:Batra, J, Soares, A.S, Radisky, E.S.
Deposit date:2011-12-23
Release date:2012-03-28
Last modified:2012-07-25
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Matrix metalloproteinase-10 (MMP-10) interaction with tissue inhibitors of metalloproteinases TIMP-1 and TIMP-2: binding studies and crystal structure.
J.Biol.Chem., 287, 2012

 

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