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6URQ
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BU of 6urq by Molmil
Complex structure of human poly-ADP-ribosyltransferase TNKS1 ARC2-ARC3 and P antigen family member 4 (PAGE4)
Descriptor: GLYCEROL, P antigen family member 4, Poly [ADP-ribose] polymerase tankyrase-1, ...
Authors:Zheng, Y, Koirala, S, Miller, D, Potts, P.R.
Deposit date:2019-10-24
Release date:2020-07-29
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Tissue-Specific Regulation of the Wnt/ beta-Catenin Pathway by PAGE4 Inhibition of Tankyrase.
Cell Rep, 32, 2020
6WJH
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BU of 6wjh by Molmil
Crystal structure of MAGE-A11 bound to the PCF11 degron
Descriptor: Fusion protein of PCF11 and MAGE-A11
Authors:Miller, D.J, Huang, X.
Deposit date:2020-04-13
Release date:2020-10-14
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:Structural basis for substrate recognition and chemical inhibition of oncogenic MAGE ubiquitin ligases.
Nat Commun, 11, 2020
6WWB
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BU of 6wwb by Molmil
Crystal Structure of the second bromodomain of human BRD2 in complex with the compound 3b
Descriptor: 1,2-ETHANEDIOL, 2-((S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)-N-((1-(4-(2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)acetamido)butyl)-1H-1,2,3-triazol-4-yl)methyl)acetamide, Bromodomain-containing protein 2
Authors:White, S.W, Yun, M.
Deposit date:2020-05-08
Release date:2021-11-17
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.31 Å)
Cite:Phenyl-Glutarimides: Alternative Cereblon Binders for the Design of PROTACs.
Angew.Chem.Int.Ed.Engl., 60, 2021
5WY5
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BU of 5wy5 by Molmil
Crystal structure of MAGEG1 and NSE1 complex
Descriptor: MAGNESIUM ION, Melanoma-associated antigen G1, Non-structural maintenance of chromosomes element 1 homolog, ...
Authors:Yang, M, Gao, J.
Deposit date:2017-01-11
Release date:2017-05-03
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.92 Å)
Cite:Mage-Ring Protein Complexes Comprise A Family Of E3 Ubiquitin Ligases.
Mol.Cell, 39, 2010

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