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3ZEV
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BU of 3zev by Molmil
Structure of Thermostable Agonist-bound Neurotensin Receptor 1 Mutant without Lysozyme Fusion
Descriptor: GLYCINE, NEUROTENSIN, NEUROTENSIN RECEPTOR 1 TM86V
Authors:Egloff, P, Hillenbrand, M, Schlinkmann, K.M, Batyuk, A, Mittl, P, Plueckthun, A.
Deposit date:2012-12-07
Release date:2014-01-29
Last modified:2014-02-26
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure of Signaling-Competent Neurotensin Receptor 1 Obtained by Directed Evolution in Escherichia Coli
Proc.Natl.Acad.Sci.USA, 111, 2014
1MJ0
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BU of 1mj0 by Molmil
SANK E3_5: an artificial Ankyrin repeat protein
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, SANK E3_5 Protein, SULFATE ION
Authors:Kohl, A, Binz, H.K, Forrer, P, Stumpp, M.T, Plueckthun, A, Gruetter, M.G.
Deposit date:2002-08-26
Release date:2003-01-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.031 Å)
Cite:Designed to be stable: Crystal structure of a consensus ankyrin repeat protein
Proc.Natl.Acad.Sci.USA, 100, 2003
4BV0
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BU of 4bv0 by Molmil
High Resolution Structure of Evolved Agonist-bound Neurotensin Receptor 1 Mutant without Lysozyme Fusion
Descriptor: NEUROTENSIN RECEPTOR TYPE 1, NEUROTENSIN/NEUROMEDIN N
Authors:Egloff, P, Hillenbrand, M, Scott, D.J, Schlinkmann, K.M, Heine, P, Balada, S, Batyuk, A, Mittl, P, Schuetz, M, Plueckthun, A.
Deposit date:2013-06-24
Release date:2014-01-29
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structure of Signaling-Competent Neurotensin Receptor 1 Obtained by Directed Evolution in Escherichia Coli
Proc.Natl.Acad.Sci.USA, 111, 2014
4BUO
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BU of 4buo by Molmil
High Resolution Structure of Thermostable Agonist-bound Neurotensin Receptor 1 Mutant without Lysozyme Fusion
Descriptor: GLYCINE, NEUROTENSIN RECEPTOR TYPE 1, NEUROTENSIN/NEUROMEDIN N
Authors:Egloff, P, Hillenbrand, M, Schlinkmann, K.M, Batyuk, A, Mittl, P, Plueckthun, A.
Deposit date:2013-06-21
Release date:2014-01-29
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Structure of Signaling-Competent Neurotensin Receptor 1 Obtained by Directed Evolution in Escherichia Coli
Proc.Natl.Acad.Sci.USA, 111, 2014
4BWB
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BU of 4bwb by Molmil
Structure of Evolved Agonist-bound Neurotensin Receptor 1 Mutant without Lysozyme Fusion
Descriptor: NEUROTENSIN, NEUROTENSIN RECEPTOR TYPE 1
Authors:Egloff, P, Hillenbrand, M, Scott, D.J, Schlinkmann, K.M, Heine, P, Balada, S, Batyuk, A, Mittl, P, Plueckthun, A.
Deposit date:2013-07-01
Release date:2014-01-29
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.57 Å)
Cite:Structure of Signaling-Competent Neurotensin Receptor 1 Obtained by Directed Evolution in Escherichia Coli
Proc.Natl.Acad.Sci.USA, 111, 2014
6F5E
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BU of 6f5e by Molmil
Crystal structure of DARPin-DARPin rigid fusion, variant DD_D12_10_47 in complex JNK1a1 and JIP1 peptide
Descriptor: C-Jun-amino-terminal kinase-interacting protein 1, DD_D12_10_47, Mitogen-activated protein kinase 8
Authors:Wu, Y, Mittl, P.R, Honegger, A, Batyuk, A, Plueckthun, A.
Deposit date:2017-12-01
Release date:2017-12-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of DARPin-DARPin rigid fusion, variant DD_D12_10_47 in complex JNK1a1 and JIP1 peptide
To be published
5AQB
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BU of 5aqb by Molmil
DARPin-based Crystallization Chaperones exploit Molecular Geometry as a Screening Dimension in Protein Crystallography
Descriptor: 3G61_DB15V4, GREEN FLUORESCENT PROTEIN
Authors:Batyuk, A, Wu, Y, Honegger, A, Heberling, M, Plueckthun, A.
Deposit date:2015-09-21
Release date:2016-03-23
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.37 Å)
Cite:Darpin-Based Crystallization Chaperones Exploit Molecular Geometry as a Screening Dimension in Protein Crystallography
J.Mol.Biol., 428, 2016
5AQ9
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BU of 5aq9 by Molmil
DARPin-based Crystallization Chaperones exploit Molecular Geometry as a Screening Dimension in Protein Crystallography
Descriptor: MALTOSE-BINDING PERIPLASMIC PROTEIN, OFF7_DB08V4
Authors:Batyuk, A, Wu, Y, Honegger, A, Heberling, M, Plueckthun, A.
Deposit date:2015-09-21
Release date:2016-03-23
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Darpin-Based Crystallization Chaperones Exploit Molecular Geometry as a Screening Dimension in Protein Crystallography
J.Mol.Biol., 428, 2016
5AQA
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BU of 5aqa by Molmil
DARPin-based Crystallization Chaperones exploit Molecular Geometry as a Screening Dimension in Protein Crystallography
Descriptor: OFF7_DB04V3, THIOCYANATE ION
Authors:Batyuk, A, Wu, Y, Honegger, A, Heberling, M, Plueckthun, A.
Deposit date:2015-09-21
Release date:2016-03-23
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Darpin-Based Crystallization Chaperones Exploit Molecular Geometry as a Screening Dimension in Protein Crystallography
J.Mol.Biol., 428, 2016
5AQ7
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BU of 5aq7 by Molmil
DARPin-based Crystallization Chaperones exploit Molecular Geometry as a Screening Dimension in Protein Crystallography
Descriptor: D12_DB04V3, MALONATE ION
Authors:Batyuk, A, Wu, Y, Honegger, A, Heberling, M, Plueckthun, A.
Deposit date:2015-09-21
Release date:2016-03-23
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Darpin-Based Crystallization Chaperones Exploit Molecular Geometry as a Screening Dimension in Protein Crystallography
J.Mol.Biol., 428, 2016
5AQ8
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BU of 5aq8 by Molmil
DARPin-based Crystallization Chaperones exploit Molecular Geometry as a Screening Dimension in Protein Crystallography
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, OFF7_DB12V4, THIOCYANATE ION
Authors:Batyuk, A, Wu, Y, Honegger, A, Heberling, M, Plueckthun, A.
Deposit date:2015-09-21
Release date:2016-03-23
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:Darpin-Based Crystallization Chaperones Exploit Molecular Geometry as a Screening Dimension in Protein Crystallography
J.Mol.Biol., 428, 2016
1KTR
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BU of 1ktr by Molmil
Crystal Structure of the Anti-His Tag Antibody 3D5 Single-Chain Fragment (scFv) in Complex with a Oligohistidine peptide
Descriptor: Anti-his tag antibody 3d5 variable light chain, Peptide linker, Anti-his tag antibody 3d5 variable heavy chain, ...
Authors:Kaufmann, M, Lindner, P, Honegger, A, Blank, K, Tschopp, M, Capitani, G, Plueckthun, A, Gruetter, M.G.
Deposit date:2002-01-17
Release date:2002-05-15
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of the anti-His tag antibody 3D5 single-chain fragment complexed to its antigen.
J.Mol.Biol., 318, 2002
5FIO
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BU of 5fio by Molmil
DARPins as a new tool for experimental phasing in protein crystallography
Descriptor: MALTOSE-BINDING PERIPLASMIC PROTEIN, MERCURY (II) ION, NI3C DARPIN MUTANT5 HG-SITE N1
Authors:Batyuk, A, Honegger, A, Andres, F, Briand, C, Gruetter, M, Plueckthun, A.
Deposit date:2015-09-30
Release date:2016-11-16
Last modified:2019-10-23
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Darpins as a New Tool for Experimental Phasing in Protein Crystallography
To be Published
5FIN
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BU of 5fin by Molmil
DARPins as a new tool for experimental phasing in protein crystallography
Descriptor: MERCURY (II) ION, NI3C DARPIN MUTANT5 HG-SITE N1
Authors:Batyuk, A, Honegger, A, Andres, F, Briand, C, Gruetter, M, Plueckthun, A.
Deposit date:2015-09-30
Release date:2016-11-16
Last modified:2017-07-05
Method:X-RAY DIFFRACTION (2.34 Å)
Cite:Darpins as a New Tool for Experimental Phasing in Protein Crystallography
To be Published
2V7N
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BU of 2v7n by Molmil
Unusual twinning in crystals of the CitS binding antibody Fab fragment f3p4
Descriptor: IMMUNOGLOBULIN HEAVY CHAIN, IMMUNOGLOBULIN LIGHT CHAIN
Authors:Frey, D, Huber, T, Plueckthun, A, Gruetter, M.G.
Deposit date:2007-07-31
Release date:2008-06-17
Last modified:2019-05-22
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Structure of the Recombinant Antibody Fab Fragment F3P4.
Acta Crystallogr.,Sect.D, 64, 2008
1SVX
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BU of 1svx by Molmil
Crystal structure of a designed selected Ankyrin Repeat protein in complex with the Maltose Binding Protein
Descriptor: Ankyrin Repeat Protein off7, Maltose-binding periplasmic protein
Authors:Binz, H.K, Amstutz, P, Kohl, A, Stumpp, M.T, Briand, C, Forrer, P, Gruetter, M.G, Plueckthun, A.
Deposit date:2004-03-30
Release date:2004-05-25
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.24 Å)
Cite:High-affinity binders selected from designed ankyrin repeat protein libraries
NAT.BIOTECHNOL., 22, 2004
1TD4
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BU of 1td4 by Molmil
Crystal structure of VSHP_BPP21 in space group H3 with high resolution.
Descriptor: Head decoration protein
Authors:Chang, C, Forrer, P, Ott, D, Wlodawer, A, Plueckthun, A.
Deposit date:2004-05-21
Release date:2004-11-02
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Kinetic Stability and Crystal Structure of the Viral Capsid Protein SHP.
J.Mol.Biol., 344, 2004
1TD0
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BU of 1td0 by Molmil
Viral capsid protein SHP at pH 5.5
Descriptor: Head decoration protein
Authors:Chang, C, Forrer, P, Ott, D, Wlodawer, A, Plueckthun, A.
Deposit date:2004-05-21
Release date:2004-11-02
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Kinetic Stability and Crystal Structure of the Viral Capsid Protein SHP
J.Mol.Biol., 344, 2004
1TD3
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BU of 1td3 by Molmil
Crystal structure of VSHP_BPP21 in space group C2
Descriptor: Head decoration protein
Authors:Chang, C, Forrer, P, Ott, D, Wlodawer, A, Plueckthun, A.
Deposit date:2004-05-21
Release date:2004-11-02
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.37 Å)
Cite:Kinetic Stability and Crystal Structure of the Viral Capsid Protein SHP.
J.Mol.Biol., 344, 2004
1TCZ
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BU of 1tcz by Molmil
Crystal structure of a truncated version of the phage lamda protein gpD
Descriptor: Head decoration protein
Authors:Chang, C, Plueckthun, A, Wlodawer, A.
Deposit date:2004-05-21
Release date:2004-06-15
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal structure of a truncated version of the phage lambda protein gpD.
Proteins, 57, 2004
4HRL
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BU of 4hrl by Molmil
Structural Basis for Eliciting a Cytotoxic Effect in HER2-Overexpressing Cancer Cells via Binding to the Extracellular Domain of HER2
Descriptor: Designed Ankyrin Repeat Protein 9_29, Receptor tyrosine-protein kinase erbB-2
Authors:Jost, C, Schilling, J, Plueckthun, A.
Deposit date:2012-10-28
Release date:2013-10-16
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Structural Basis for Eliciting a Cytotoxic Effect in HER2-Overexpressing Cancer Cells via Binding to the Extracellular Domain of HER2.
Structure, 21, 2013
4HRN
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BU of 4hrn by Molmil
Structural Basis for Eliciting a Cytotoxic Effect in HER2-Overexpressing Cancer Cells via Binding to the Extracellular Domain of HER2
Descriptor: Designed Ankyrin Repeat Protein H10-2-G, Receptor tyrosine-protein kinase erbB-2
Authors:Jost, C, Schilling, J, Plueckthun, A.
Deposit date:2012-10-28
Release date:2013-10-16
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structural Basis for Eliciting a Cytotoxic Effect in HER2-Overexpressing Cancer Cells via Binding to the Extracellular Domain of HER2.
Structure, 21, 2013
4HRM
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BU of 4hrm by Molmil
Structural Basis for Eliciting a Cytotoxic Effect in HER2-Overexpressing Cancer Cells via Binding to the Extracellular Domain of HER2
Descriptor: Designed Ankyrin Repeat Protein 9_26, Domain I of receptor tyrosine-protein kinase erbB-2
Authors:Jost, C, Schilling, J, Plueckthun, A.
Deposit date:2012-10-28
Release date:2013-10-16
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural Basis for Eliciting a Cytotoxic Effect in HER2-Overexpressing Cancer Cells via Binding to the Extracellular Domain of HER2.
Structure, 21, 2013
4K5C
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BU of 4k5c by Molmil
From DARPins to LoopDARPins: Novel LoopDARPin Design Allows the Selection of Low Picomolar Binders in a Single Round of Ribosome Display
Descriptor: Loop Designed Ankyrin Repeat Protein Nran1_G06_C
Authors:Schilling, J, Schoeppe, J, Plueckthun, A.
Deposit date:2013-04-14
Release date:2013-11-13
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:From DARPins to LoopDARPins: novel LoopDARPin design allows the selection of low picomolar binders in a single round of ribosome display
J.Mol.Biol., 426, 2014
7DNE
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BU of 7dne by Molmil
DARPin 5m3_D12 in complex with V3-IY (MN) crown mimetic
Descriptor: DARPin 5m3_D12, V3-IY (MN) crown mimetic peptide
Authors:Wu, Y, Plueckthun, A.
Deposit date:2020-12-09
Release date:2021-12-22
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Distinct conformations of the HIV-1 V3 loop crown are targetable for broad neutralization.
Nat Commun, 12, 2021

 

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