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1IM3
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BU of 1im3 by Molmil
Crystal Structure of the human cytomegalovirus protein US2 bound to the MHC class I molecule HLA-A2/tax
Descriptor: HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, A-2 ALPHA CHAIN, Human T-cell lymphotropic virus type 1 Tax peptide, ...
Authors:Gewurz, B.E, Gaudet, R, Tortorella, D, Wang, E.W, Ploegh, H.L, Wiley, D.C.
Deposit date:2001-05-09
Release date:2001-06-06
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Antigen presentation subverted: Structure of the human cytomegalovirus protein US2 bound to the class I molecule HLA-A2.
Proc.Natl.Acad.Sci.USA, 98, 2001
1XD3
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BU of 1xd3 by Molmil
Crystal structure of UCHL3-UbVME complex
Descriptor: MAGNESIUM ION, METHYL 4-AMINOBUTANOATE, UBC protein, ...
Authors:Misaghi, S, Galardy, P.J, Meester, W.J.N, Ovaa, H, Ploegh, H.L, Gaudet, R.
Deposit date:2004-09-03
Release date:2004-11-23
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Structure of the Ubiquitin Hydrolase UCH-L3 Complexed with a Suicide Substrate
J.Biol.Chem., 280, 2005
2VE6
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BU of 2ve6 by Molmil
Crystal structure of a Murine MHC class I H2-Db molecule in complex with a photocleavable peptide
Descriptor: BETA-2-MICROGLOBULIN, H-2 CLASS I HISTOCOMPATIBILITY ANTIGEN D-B ALPHA CHAIN, SENDAI VIRUS EPITOPE RESIDUES 324-332 MODIFIED AT P7
Authors:Grotenbreg, G.M, Roan, N.R, Guillen, E, Meijers, R, Wang, J.H, Bell, G.W, Starnbach, M.N, Ploegh, H.L.
Deposit date:2007-10-17
Release date:2008-01-22
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Discovery of Cd8+ T Cell Epitopes in Chlamydia Trachomatis Infection Through Use of Caged Class I Mhc Tetramers.
Proc.Natl.Acad.Sci.USA, 105, 2008
2WDT
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BU of 2wdt by Molmil
Crystal structure of Plasmodium falciparum UCHL3 in complex with the suicide inhibitor UbVME
Descriptor: CHLORIDE ION, UBIQUITIN, UBIQUITIN CARBOXYL-TERMINAL HYDROLASE L3
Authors:Weihofen, W.A, Artavanis-Tsakonas, K, Gaudet, R, Ploegh, H.L.
Deposit date:2009-03-26
Release date:2009-12-29
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Characterization and Structural Studies of the Plasmodium Falciparum Ubiquitin and Nedd8 Hydrolase Uchl3.
J.Biol.Chem., 285, 2010
2WE6
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BU of 2we6 by Molmil
Crystal Structure of Plasmodium falciparum Ubiquitin Carboxyl- terminal Hydrolase 3 (UCHL3)
Descriptor: UBIQUITIN CARBOXYL-TERMINAL HYDROLASE L3
Authors:Weihofen, W.A, Artavanis-Tsakonas, K, Gaudet, R, Ploegh, H.L.
Deposit date:2009-03-27
Release date:2009-12-29
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.42 Å)
Cite:Characterization and Structural Studies of the Plasmodium Falciparum Ubiquitin and Nedd8 Hydrolase Uchl3.
J.Biol.Chem., 285, 2010
5TJW
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BU of 5tjw by Molmil
Influenza A virus Nucleoprotein in Complex with Inhibitory Nanobody
Descriptor: NP-specific inhibitory VHH, Nucleoprotein
Authors:Hanke, L, Knockenhauer, K.E, Ploegh, H.L, Schwartz, T.U.
Deposit date:2016-10-05
Release date:2016-12-21
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.231 Å)
Cite:The Antiviral Mechanism of an Influenza A Virus Nucleoprotein-Specific Single-Domain Antibody Fragment.
MBio, 7, 2016
5UKB
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BU of 5ukb by Molmil
VSV N PROTEIN IN COMPLEX WITH INHIBITORY NANOBODY 1004
Descriptor: Anti-vesicular stomatitis virus N VHH, Nucleocapsid, RNA (45-MER)
Authors:Hanke, L, Knockenhauer, K.E, Ploegh, H.L, Schwartz, T.U.
Deposit date:2017-01-20
Release date:2017-04-19
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (5.473 Å)
Cite:Vesicular stomatitis virus N protein-specific single-domain antibody fragments inhibit replication.
EMBO Rep., 18, 2017
5UK4
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BU of 5uk4 by Molmil
VESICULAR STOMATITS VIRUS N PROTEIN IN COMPLEX WITH INHIBITORY NANOBODY 1307
Descriptor: Anti-vesicular stomatitis virus N VHH, Nucleoprotein, RNA (45-MER)
Authors:Hanke, L, Knockenhauer, K.E, Ploegh, H.L, Schwartz, T.U.
Deposit date:2017-01-19
Release date:2017-04-19
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.204 Å)
Cite:Vesicular stomatitis virus N protein-specific single-domain antibody fragments inhibit replication.
EMBO Rep., 18, 2017
2J7Q
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BU of 2j7q by Molmil
Crystal structure of the ubiquitin-specific protease encoded by murine cytomegalovirus tegument protein M48 in complex with a ubquitin-based suicide substrate
Descriptor: GLYCEROL, MAGNESIUM ION, MCMV TEGUMENT PROTEIN M48 ENCODED UBIQUITIN- SPECIFIC PROTEASE, ...
Authors:Schlieker, C, Weihofen, W.A, Frijns, E, Kattenhorn, L.M, Gaudet, R, Ploegh, H.L.
Deposit date:2006-10-16
Release date:2007-03-20
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure of a Herpesvirus-Encoded Cysteine Protease Reveals a Unique Class of Deubiquitinating Enzymes
Mol.Cell, 25, 2007
2JX5
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BU of 2jx5 by Molmil
Solution structure of the ubiquitin domain N-terminal to the S27a ribosomal subunit of Giardia lamblia
Descriptor: GlUb(S27a)
Authors:Catic, A, Sun, Z.J, Ratner, D.M, Misaghi, S, Spooner, E, Samuelson, J, Wagner, G, Ploegh, H.L.
Deposit date:2007-11-07
Release date:2007-12-04
Last modified:2022-03-16
Method:SOLUTION NMR
Cite:Sequence and structure evolved separately in a ribosomal ubiquitin variant
EMBO J., 26, 2007
5H8O
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BU of 5h8o by Molmil
Crystal structure of an ASC-binding nanobody in complex with the CARD domain of ASC
Descriptor: Apoptosis-associated speck-like protein containing a CARD, VHH nanobody
Authors:Lu, A, Schmidt, F.I, Ruan, J, Tang, C, Wu, H, Ploegh, H.L.
Deposit date:2015-12-23
Release date:2016-04-06
Last modified:2016-05-18
Method:X-RAY DIFFRACTION (4.206 Å)
Cite:A single domain antibody fragment that recognizes the adaptor ASC defines the role of ASC domains in inflammasome assembly.
J.Exp.Med., 213, 2016
5H8D
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BU of 5h8d by Molmil
Crystal structure of an ASC binding nanobody
Descriptor: VHH nanobody
Authors:Lu, A, Schmidt, F.I, Ruan, J, Tang, C, Wu, H, Ploegh, H.L.
Deposit date:2015-12-23
Release date:2016-04-06
Last modified:2016-05-18
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:A single domain antibody fragment that recognizes the adaptor ASC defines the role of ASC domains in inflammasome assembly.
J.Exp.Med., 213, 2016
5FNA
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BU of 5fna by Molmil
Cryo-EM reconstruction of caspase-1 CARD
Descriptor: Caspase-1
Authors:Li, Y, Lu, A, Schmidt, F.I, Yin, Q, Chen, S, Fu, T.M, Tong, A.B, Ploegh, H.L, Mao, Y, Wu, H.
Deposit date:2015-11-11
Release date:2016-03-30
Last modified:2019-09-11
Method:ELECTRON MICROSCOPY (4.8 Å)
Cite:Molecular Basis of Caspase-1 Polymerization and its Inhibition by a Novel Capping Mechanism
Nat.Struct.Mol.Biol., 23, 2016
5KTE
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BU of 5kte by Molmil
Crystal structure of Deinococcus radiodurans MntH, an Nramp-family transition metal transporter
Descriptor: Divalent metal cation transporter MntH, Fab Heavy Chain, Fab Light Chain, ...
Authors:Bane, L.B, Gaudet, R, Weihofen, W.A, Singharoy, A.
Deposit date:2016-07-11
Release date:2016-11-23
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.941 Å)
Cite:Crystal Structure and Conformational Change Mechanism of a Bacterial Nramp-Family Divalent Metal Transporter.
Structure, 24, 2016
3H1D
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BU of 3h1d by Molmil
Structure of the HUWE1 HECT Domain
Descriptor: E3 ubiquitin-protein ligase HUWE1, SULFATE ION
Authors:Partridge, J.R, Schwartz, T.U.
Deposit date:2009-04-11
Release date:2009-12-08
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.892 Å)
Cite:A structural element within the HUWE1 HECT domain modulates self-ubiquitination and substrate ubiquitination activities.
J.Biol.Chem., 285, 2010
4XT3
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BU of 4xt3 by Molmil
Structure of a viral GPCR bound to human chemokine CX3CL1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fractalkine, G-protein coupled receptor homolog US28, ...
Authors:Burg, J.S, Jude, K.M, Waghray, D, Garcia, K.C.
Deposit date:2015-01-22
Release date:2015-03-04
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.801 Å)
Cite:Structural biology. Structural basis for chemokine recognition and activation of a viral G protein-coupled receptor.
Science, 347, 2015
4XT1
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BU of 4xt1 by Molmil
Structure of a nanobody-bound viral GPCR bound to human chemokine CX3CL1
Descriptor: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, CHOLESTEROL, Fractalkine, ...
Authors:Burg, J.S, Jude, K.M, Waghray, D, Garcia, K.C.
Deposit date:2015-01-22
Release date:2015-03-04
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.886 Å)
Cite:Structural biology. Structural basis for chemokine recognition and activation of a viral G protein-coupled receptor.
Science, 347, 2015
4QXW
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BU of 4qxw by Molmil
Crystal structure of the human CEACAM1 membrane distal amino terminal (N)-domain
Descriptor: Carcinoembryonic antigen-related cell adhesion molecule 1, MALONIC ACID, octyl beta-D-glucopyranoside
Authors:Huang, Y.H, Gandhi, A.K, Russell, A, Kondo, Y, Chen, Q, Petsko, G.A, Blumberg, R.S.
Deposit date:2014-07-22
Release date:2014-11-12
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:CEACAM1 regulates TIM-3-mediated tolerance and exhaustion.
Nature, 517, 2015
4YGA
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BU of 4yga by Molmil
CDPK1, from Toxoplasma gondii, bound to inhibitory VHH-1B7
Descriptor: CALCIUM ION, Calmodulin-domain protein kinase 1, VHH-1B7
Authors:Knockenhauer, K.E, Schwartz, T.U.
Deposit date:2015-02-26
Release date:2015-08-26
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (2.94 Å)
Cite:Allosteric activation of apicomplexan calcium-dependent protein kinases.
Proc.Natl.Acad.Sci.USA, 112, 2015
4TVS
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BU of 4tvs by Molmil
LAP1(aa356-583), H.sapiens, bound to VHH-BS1
Descriptor: GLYCEROL, SULFATE ION, Torsin-1A-interacting protein 1, ...
Authors:Sosa, B.A, Schwartz, T.U.
Deposit date:2014-06-27
Release date:2014-09-03
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:How lamina-associated polypeptide 1 (LAP1) activates Torsin.
Elife, 3, 2014
6X08
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BU of 6x08 by Molmil
Nup85-Seh1 from S. cerevisiae bound by VHH-SAN2
Descriptor: Nucleoporin NUP85, Nucleoporin SEH1, VHH-SAN2
Authors:Nordeen, S.A, Schwartz, T.U.
Deposit date:2020-05-15
Release date:2020-12-09
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (4.19 Å)
Cite:A nanobody suite for yeast scaffold nucleoporins provides details of the nuclear pore complex structure.
Nat Commun, 11, 2020
6X07
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BU of 6x07 by Molmil
Nic96 from S. cerevisiae bound by VHH-SAN12
Descriptor: Nucleoporin NIC96, VHH-SAN12
Authors:Andersen, K, Nordeen, S.A, Schwartz, T.U.
Deposit date:2020-05-15
Release date:2020-12-09
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:A nanobody suite for yeast scaffold nucleoporins provides details of the nuclear pore complex structure.
Nat Commun, 11, 2020
6X06
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BU of 6x06 by Molmil
Nup120 (aa1-757) from S. cerevisiae bound by VHH-SAN11
Descriptor: Nucleoporin NUP120, VHH-SAN11
Authors:Knockenhauer, K.E, Nordeen, S.A, Schwartz, T.U.
Deposit date:2020-05-15
Release date:2020-12-09
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (4.27 Å)
Cite:A nanobody suite for yeast scaffold nucleoporins provides details of the nuclear pore complex structure.
Nat Commun, 11, 2020
5WB1
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BU of 5wb1 by Molmil
Ligand-free US28 with stabilizing intracellular nanobody
Descriptor: Envelope protein US28, nanobody 7 fusion protein
Authors:Jude, K.M, Burg, J.S, Garcia, K.C.
Deposit date:2017-06-27
Release date:2018-06-13
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.508 Å)
Cite:Viral GPCR US28 can signal in response to chemokine agonists of nearly unlimited structural degeneracy.
Elife, 7, 2018
2F16
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BU of 2f16 by Molmil
Crystal structure of the yeast 20S proteasome in complex with bortezomib
Descriptor: N-[(1R)-1-(DIHYDROXYBORYL)-3-METHYLBUTYL]-N-(PYRAZIN-2-YLCARBONYL)-L-PHENYLALANINAMIDE, Proteasome component C1, Proteasome component C11, ...
Authors:Groll, M.
Deposit date:2005-11-14
Release date:2006-03-21
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal Structure of the Boronic Acid-Based Proteasome Inhibitor Bortezomib in Complex with the Yeast 20S Proteasome.
Structure, 14, 2006

 

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