Author results

4FHA
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STRUCTURE OF DIHYDRODIPICOLINATE SYNTHASE FROM STREPTOCOCCUS PNEUMONIAE,BOUND TO PYRUVATE AND LYSINE
Descriptor:Dihydrodipicolinate synthase, LYSINE, SODIUM ION
Authors:Perugini, M.A., Dogovski, C., Parker, M.W., Gorman, M.A.
Deposit date:2012-06-06
Release date:2013-09-18
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Structure, Function, Stability and Knockout Phenotype of Dihydrodipicolinate Synthase from Streptococcus pneumoniae
To be Published
3TUU
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STRUCTURE OF DIHYDRODIPICOLINATE SYNTHASE FROM THE COMMON GRAPEVINE
Descriptor:dihydrodipicolinate synthase, BROMIDE ION, CHLORIDE ION
Authors:Perugini, M.A., Dobson, R.C., Atkinson, S.C.
Deposit date:2011-09-19
Release date:2012-07-25
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal, Solution and In silico Structural Studies of Dihydrodipicolinate Synthase from the Common Grapevine.
Plos One, 7, 2012
3HIJ
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CRYSTAL STRUCTURE OF DIHYDRODIPICOLINATE SYNTHASE FROM BACILLUS ANTHRACIS IN COMPLEX WITH ITS SUBSTRATE, PYRUVATE
Descriptor:Dihydrodipicolinate synthase, GLYCEROL, SODIUM ION
Authors:Voss, J.E., Scally, S.W., Dobson, R.C.J., Perugini, M.A.
Deposit date:2009-05-20
Release date:2009-11-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Substrate-mediated Stabilization of a Tetrameric Drug Target Reveals Achilles Heel in Anthrax.
J.Biol.Chem., 285, 2010
4JO8
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CRYSTAL STRUCTURE OF THE ACTIVATING LY49H RECEPTOR IN COMPLEX WITH M157 (G1F STRAIN)
Descriptor:M157, Killer cell lectin-like receptor 8, N-ACETYL-D-GLUCOSAMINE
Authors:Berry, R., Ng, N., Saunders, P.M., Vivian, J.P., Lin, J., Deuss, F.A., Corbett, A.J., Forbes, C.A., Widjaja, J.M., Sullivan, L.C., McAlister, A.D., Perugini, M.A., Call, M.J., Scalzo, A.A., Degli-Esposti, M.A., Coudert, J.D., Beddoe, T., Brooks, A.G., Rossjohn, J.
Deposit date:2013-03-18
Release date:2013-05-22
Last modified:2013-07-10
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Targeting of a natural killer cell receptor family by a viral immunoevasin
Nat.Immunol., 14, 2013
3DEN
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STRUCTURE OF E. COLI DHDPS MUTANT Y107W
Descriptor:Dihydrodipicolinate synthase, POTASSIUM ION, GLYCEROL, ...
Authors:Pearce, F.G., Gerrard, J.A., Perugini, M.A., Jameson, G.B.
Deposit date:2008-06-10
Release date:2008-11-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Mutating the tight-dimer interface of dihydrodipicolinate synthase disrupts the enzyme quaternary structure: toward a monomeric enzyme
Biochemistry, 47, 2008
1PY9
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THE CRYSTAL STRUCTURE OF AN AUTOANTIGEN IN MULTIPLE SCLEROSIS
Descriptor:Myelin-oligodendrocyte glycoprotein, SULFATE ION
Authors:Clements, C.S., Reid, H.H., Beddoe, T., Tynan, F.E., Perugini, M.A., Johns, T.G., Bernard, C.C., Rossjohn, J.
Deposit date:2003-07-08
Release date:2003-09-30
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The crystal structure of myelin oligodendrocyte glycoprotein, a key autoantigen in multiple sclerosis
Proc.Natl.Acad.Sci.USA, 100, 2003
2OJP
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THE CRYSTAL STRUCTURE OF A DIMERIC MUTANT OF DIHYDRODIPICOLINATE SYNTHASE FROM E.COLI- DHDPS-L197Y
Descriptor:Dihydrodipicolinate synthase, GLYCEROL
Authors:Griffin, M.D.W., Dobson, R.C.J., Antonio, L., Perugini, M.A., Jameson, G.B., Gerrard, J.A.
Deposit date:2007-01-13
Release date:2008-01-01
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Evolution of quaternary structure in a homotetrameric enzyme.
J.Mol.Biol., 380, 2008
2VTY
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VACCINIA VIRUS ANTI-APOPTOTIC F1L IS A NOVEL BCL-2-LIKE DOMAIN SWAPPED DIMER
Descriptor:PROTEIN F1
Authors:Kvansakul, M., Yang, H., Fairlie, W.D., Czabotar, P.E., Fischer, S.F., Perugini, M.A., Huang, D.C.S., Colman, P.M.
Deposit date:2008-05-19
Release date:2008-06-24
Last modified:2012-01-18
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Vaccinia Virus Anti-Apoptotic F1L is a Novel Bcl-2-Like Domain-Swapped Dimer that Binds a Highly Selective Subset of Bh3-Containing Death Ligands.
Cell Death Differ., 15, 2008
2Y6W
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STRUCTURE OF A BCL-W DIMER
Descriptor:BCL-2-LIKE PROTEIN 2, DI(HYDROXYETHYL)ETHER, TRIETHYLENE GLYCOL
Authors:Lee, E.F., Evangelista, M., Pettikiriarachchi, A., Dogovski, C., Perugini, M.A., Colman, P.M., Fairlie, W.D.
Deposit date:2011-01-27
Release date:2011-10-26
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structure of a Bcl-W Domain-Swapped Dimer: Implications for the Function of Bcl-2 Family Proteins.
Structure, 19, 2011
3DAQ
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CRYSTAL STRUCTURE OF DIHYDRODIPICOLINATE SYNTHASE FROM METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS
Descriptor:Dihydrodipicolinate synthase, CHLORIDE ION, GLYCEROL
Authors:Dobson, R.C.J., Burgess, B.R., Jameson, G.B., Gerrard, J.A., Parker, M.W., Perugini, M.A.
Deposit date:2008-05-29
Release date:2008-08-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Structure and evolution of a novel dimeric enzyme from a clinically-important bacterial pathogen.
J.Biol.Chem., 2008
3IRD
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STRUCTURE OF DIHYDRODIPICOLINATE SYNTHASE FROM CLOSTRIDIUM BOTULINUM
Descriptor:Dihydrodipicolinate synthase, D-MALATE, SODIUM ION, ...
Authors:Dobson, R.C.J., Atkinson, S., Perugini, M.A.
Deposit date:2009-08-22
Release date:2009-09-22
Last modified:2018-06-20
Method:X-RAY DIFFRACTION (2.23 Å)
Cite:Structure of Cbot-DHDPS
To be Published
4HNN
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DIHYDRODIPICOLINATE SYNTHASE FROM THE COMMON GRAPEVINE WITH PYRUVATE AND LYSINE
Descriptor:Dihydrodipicolinate synthase, LYSINE
Authors:Atkinson, S.C., Dobson, R.C.J., Perugini, M.A.
Deposit date:2012-10-19
Release date:2013-09-04
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural, kinetic and computational investigation of Vitis vinifera DHDPS reveals new insight into the mechanism of lysine-mediated allosteric inhibition.
Plant Mol.Biol., 81, 2013
4I7U
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DIHYDRODIPICOLINATE SYNTHASE OF AGROBACTERIUM TUMEFACIENS
Descriptor:Dihydrodipicolinate synthase, GLYCEROL
Authors:Atkinson, S.C., Dogovski, C., Dobson, R.C.J., Perugini, M.A.
Deposit date:2012-11-30
Release date:2013-12-04
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structure, function and allostery of the bona fide DHDPS from the plant pathogen Agrobacterium tumefaciens
To be Published
4I7V
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AGROBACTERIUM TUMEFACIENS DHDPS WITH PYRUVATE
Descriptor:Dihydrodipicolinate synthase
Authors:Atkinson, S.C., Dogovski, C., Dobson, R.C.J., Perugini, M.A.
Deposit date:2012-12-01
Release date:2013-12-04
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Structure, function and allostery of the bona fide DHDPS from the plant pathogen Agrobacterium tumefaciens
To be Published
4I7W
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AGROBACTERIUM TUMEFACIENS DHDPS WITH LYSINE AND PYRUVATE
Descriptor:Dihydrodipicolinate synthase, LYSINE, GLYCEROL
Authors:Atkinson, S.C., Dogovski, C., Dobson, R.C.J., Perugini, M.A.
Deposit date:2012-12-01
Release date:2013-12-04
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Structure, function and allostery of the bona fide DHDPS from the plant pathogen Agrobacterium tumefaciens
To be Published
4ICN
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DIHYDRODIPICOLINATE SYNTHASE FROM SHEWANELLA BENTHICA
Descriptor:DIHYDRODIPICOLINATE SYNTHASE, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLYCEROL, ...
Authors:Wubben, J.M., Paxman, J.J., Dogovski, C., Parker, M.W., Perugini, M.A.
Deposit date:2012-12-10
Release date:2013-12-11
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Cold enzymology offers insight into molecular evolution in quaternary structure
To be Published
4IJZ
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CRYSTAL STRUCTURE OF DIAMINOPIMELATE EPIMERASE FROM ESCHERICHIA COLI
Descriptor:Diaminopimelate epimerase, NITRATE ION
Authors:Hor, L., Dobson, R.C.J., Hutton, C.A., Perugini, M.A.
Deposit date:2012-12-24
Release date:2013-02-20
Last modified:2013-04-17
Method:X-RAY DIFFRACTION (2 Å)
Cite:Dimerization of bacterial diaminopimelate epimerase is essential for catalysis
J.Biol.Chem., 288, 2013
4IK0
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CRYSTAL STRUCTURE OF DIAMINOPIMELATE EPIMERASE Y268A MUTANT FROM ESCHERICHIA COLI
Descriptor:Diaminopimelate epimerase, IODIDE ION
Authors:Hor, L., Dobson, R.C.J., Hutton, C.A., Perugini, M.A.
Deposit date:2012-12-24
Release date:2013-02-20
Last modified:2013-04-17
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Dimerization of bacterial diaminopimelate epimerase is essential for catalysis
J.Biol.Chem., 288, 2013
4PFM
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SHEWANELLA BENTHICA DHDPS WITH LYSINE AND PYRUVATE
Descriptor:4-hydroxy-tetrahydrodipicolinate synthase, LYSINE, GLYCEROL, ...
Authors:Wubben, J.M., Paxman, J.J., Dogovski, C., Panjikar, S., Perugini, M.A.
Deposit date:2014-04-30
Release date:2015-05-06
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.327 Å)
Cite:Defining a Molecular Determinant of Lysine-Mediated Allosteric Inhibition of DHDPS.
To Be Published
4XG1
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PSYCHROMONAS INGRAHAMII DIAMINOPIMELATE DECARBOXYLASE WITH LLP
Descriptor:Diaminopimelate decarboxylase, THIOCYANATE ION, POTASSIUM ION, ...
Authors:Peverelli, M.G., Wubben, J.M., Panjikar, S., Perugini, M.A.
Deposit date:2014-12-30
Release date:2016-03-09
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Expression to crystallization of diaminopimelate decarboxylase from the psychrophile Psychromonas ingrahamii
To Be Published
5KT0
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DIHYDRODIPICOLINATE REDUCTASE FROM THE INDUSTRIAL AND EVOLUTIONARILY IMPORTANT CYANOBACTERIA ANABAENA VARIABILIS.
Descriptor:4-hydroxy-tetrahydrodipicolinate reductase, MAGNESIUM ION
Authors:Christensen, J.B., Soares da Costa, T.P., Faou, P., Pearce, F.G., Panjikar, S., Perugini, M.A.
Deposit date:2016-07-10
Release date:2016-09-07
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (2.83 Å)
Cite:Dihydrodipicolinate Reductase from the industrial and evolutionarily important cyanobacteria Anabaena variabilis.
To Be Published
3VFL
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STRUCTURE, FUNCTION, STABILITY AND KNOCKOUT PHENOTYPE OF DIHYDRODIPICOLINATE SYNTHASE FROM STREPTOCOCCUS PNEUMONIAE
Descriptor:Dihydrodipicolinate synthase, POTASSIUM ION, GLYCEROL, ...
Authors:Gorman, M.A.
Deposit date:2012-01-10
Release date:2013-06-12
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:Structure, Function, Stability and Knockout Phenotype of Dihydrodipicolinate Synthase from Streptococcus pneumoniae
To be Published
5KTL
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DIHYDRODIPICOLINATE SYNTHASE FROM THE INDUSTRIAL AND EVOLUTIONARILY IMPORTANT CYANOBACTERIA ANABAENA VARIABILIS.
Descriptor:4-hydroxy-tetrahydrodipicolinate synthase, MANGANESE (II) ION
Authors:Christensen, J.B., Panjikar, S., Perugini, M.
Deposit date:2016-07-11
Release date:2016-11-30
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Structure and Function of Cyanobacterial DHDPS and DHDPR.
Sci Rep, 6, 2016
3HA4
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CRYSTAL STRUCTURE OF THE TYPE ONE MEMBRANE PROTEIN MIX1 FROM LEISHMANIA
Descriptor:MIX1, CARBONATE ION
Authors:Gorman, M.A., Walsh, P.J., Parker, M.W.
Deposit date:2009-05-01
Release date:2010-05-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of the Leishmania major MIX protein: A scaffold protein that mediates protein-protein interactions.
Protein Sci., 20, 2011
4KH3
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STRUCTURE OF A BACTERIAL SELF-ASSOCIATING PROTEIN
Descriptor:Antigen 43, MALONATE ION
Authors:Heras, B., Gee, C.L., Schembri, M.A., Totsika, M.
Deposit date:2013-04-30
Release date:2014-01-15
Last modified:2015-06-17
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The antigen 43 structure reveals a molecular Velcro-like mechanism of autotransporter-mediated bacterial clumping.
Proc.Natl.Acad.Sci.USA, 111, 2014
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