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1APO
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BU of 1apo by Molmil
THREE-DIMENSIONAL STRUCTURE OF THE APO FORM OF THE N-TERMINAL EGF-LIKE MODULE OF BLOOD COAGULATION FACTOR X AS DETERMINED BY NMR SPECTROSCOPY AND SIMULATED FOLDING
Descriptor: EGF-LIKE MODULE OF BLOOD COAGULATION FACTOR X, HYDROXIDE ION
Authors:Ullner, M, Selander, M, Persson, E, Stenflo, J, Drakenberg, T, Teleman, O.
Deposit date:1992-04-21
Release date:1994-01-31
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:Three-dimensional structure of the apo form of the N-terminal EGF-like module of blood coagulation factor X as determined by NMR spectroscopy and simulated folding.
Biochemistry, 31, 1992
5YUP
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BU of 5yup by Molmil
Crystal Structure of the Fab fragment of FVIIa antibody mAb4F5
Descriptor: the heavy chain of the Fab fragment of FVIIa antibody mAb4F5, the light chain of the Fab fragment of FVIIa antibody mAb4F5
Authors:Jiang, L.G, Persson, E, Huang, M.D.
Deposit date:2017-11-22
Release date:2019-06-19
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.81 Å)
Cite:Crystal structure, epitope, and functional impact of an antibody against a superactive FVIIa provide insights into allosteric mechanism.
Res Pract Thromb Haemost, 3, 2019
1QFK
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BU of 1qfk by Molmil
STRUCTURE OF HUMAN FACTOR VIIA AND ITS IMPLICATIONS FOR THE TRIGGERING OF BLOOD COAGULATION
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, COAGULATION FACTOR VIIA HEAVY CHAIN, ...
Authors:Pike, A.C.W, Brzozowski, A.M, Roberts, S.M, Olsen, O.H, Persson, E.
Deposit date:1999-04-12
Release date:1999-08-01
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of human factor VIIa and its implications for the triggering of blood coagulation.
Proc.Natl.Acad.Sci.USA, 96, 1999
1CCF
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BU of 1ccf by Molmil
How an Epidermal Growth Factor (EGF)-Like Domain Binds Calcium-High Resolution NMR Structure of the Calcium Form of the NH2-Terminal EGF-Like Domain in Coagulation Factor X
Descriptor: COAGULATION FACTOR X
Authors:Selander-Sunnerhagen, M, Ullner, M, Persson, M, Teleman, O, Stenflo, J, Drakenberg, T.
Deposit date:1993-05-19
Release date:1994-05-31
Last modified:2023-11-15
Method:SOLUTION NMR
Cite:How an epidermal growth factor (EGF)-like domain binds calcium. High resolution NMR structure of the calcium form of the NH2-terminal EGF-like domain in coagulation factor X.
J.Biol.Chem., 267, 1992
6R2W
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BU of 6r2w by Molmil
Crystal structure of the super-active FVIIa variant VYT in complex with tissue factor
Descriptor: CALCIUM ION, Coagulation factor VII, N-acetyl-D-phenylalanyl-N-[(2S,3S)-6-carbamimidamido-1-chloro-2-hydroxyhexan-3-yl]-L-phenylalaninamide, ...
Authors:Sorensen, A.B, Svensson, L.A, Gandhi, P.S.
Deposit date:2019-03-19
Release date:2019-12-11
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Beating tissue factor at its own game: Design and properties of a soluble tissue factor-independent coagulation factor VIIa.
J.Biol.Chem., 295, 2020
1WHF
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BU of 1whf by Molmil
COAGULATION FACTOR, NMR, 15 STRUCTURES
Descriptor: COAGULATION FACTOR X
Authors:Sunnerhagen, M, Olah, G.A, Stenflo, J, Forsen, S, Drakenberg, T, Trewhella, J.
Deposit date:1996-06-18
Release date:1997-05-15
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:The relative orientation of Gla and EGF domains in coagulation factor X is altered by Ca2+ binding to the first EGF domain. A combined NMR-small angle X-ray scattering study.
Biochemistry, 35, 1996
1WHE
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BU of 1whe by Molmil
COAGULATION FACTOR, NMR, 20 STRUCTURES
Descriptor: COAGULATION FACTOR X
Authors:Sunnerhagen, M, Olah, G.A, Stenflo, J, Forsen, S, Drakenberg, T, Trewhella, J.
Deposit date:1996-06-18
Release date:1997-05-15
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:The relative orientation of Gla and EGF domains in coagulation factor X is altered by Ca2+ binding to the first EGF domain. A combined NMR-small angle X-ray scattering study.
Biochemistry, 35, 1996
1BF9
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BU of 1bf9 by Molmil
N-TERMINAL EGF-LIKE DOMAIN FROM HUMAN FACTOR VII, NMR, 23 STRUCTURES
Descriptor: FACTOR VII
Authors:Muranyi, A, Finn, B.E, Gippert, G.P, Forsen, S, Stenflo, J, Drakenberg, T.
Deposit date:1998-05-28
Release date:1999-02-16
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:Solution structure of the N-terminal EGF-like domain from human factor VII.
Biochemistry, 37, 1998
1HCG
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BU of 1hcg by Molmil
STRUCTURE OF HUMAN DES(1-45) FACTOR XA AT 2.2 ANGSTROMS RESOLUTION
Descriptor: BLOOD COAGULATION FACTOR XA
Authors:Tulinsky, A, Padmanabhan, K.
Deposit date:1993-05-05
Release date:1995-05-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of human des(1-45) factor Xa at 2.2 A resolution.
J.Mol.Biol., 232, 1993
1JBU
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BU of 1jbu by Molmil
Coagulation Factor VII Zymogen (EGF2/Protease) in Complex with Inhibitory Exosite Peptide A-183
Descriptor: BENZAMIDINE, COAGULATION FACTOR VII, Peptide exosite inhibitor A-183, ...
Authors:Eigenbrot, C, Kirchhofer, D, Dennis, M.S, Santell, L, Lazarus, R.A, Stamos, J, Ultsch, M.H.
Deposit date:2001-06-06
Release date:2001-07-11
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2 Å)
Cite:The factor VII zymogen structure reveals reregistration of beta strands during activation.
Structure, 9, 2001
3ELA
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BU of 3ela by Molmil
Crystal structure of active site inhibited coagulation factor VIIA mutant in complex with soluble tissue factor
Descriptor: CALCIUM ION, Coagulation factor VIIA heavy chain, Coagulation factor VIIA light chain, ...
Authors:Bjelke, J.R, Fodje, M, Svensson, L.A.
Deposit date:2008-09-21
Release date:2008-11-04
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Mechanism of the Ca2+-induced enhancement of the intrinsic factor VIIa activity
J.Biol.Chem., 283, 2008

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