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1SAC
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BU of 1sac by Molmil
THE STRUCTURE OF PENTAMERIC HUMAN SERUM AMYLOID P COMPONENT
Descriptor: ACETIC ACID, CALCIUM ION, SERUM AMYLOID P COMPONENT
Authors:White, H.E, Emsley, J, O'Hara, B.P, Oliva, G, Srinivasan, N, Tickle, I.J, Blundell, T.L, Pepys, M.B, Wood, S.P.
Deposit date:1994-01-27
Release date:1994-05-31
Last modified:2019-08-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of pentameric human serum amyloid P component.
Nature, 367, 1994
1B09
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BU of 1b09 by Molmil
HUMAN C-REACTIVE PROTEIN COMPLEXED WITH PHOSPHOCHOLINE
Descriptor: CALCIUM ION, PHOSPHOCHOLINE, PROTEIN (C-REACTIVE PROTEIN)
Authors:Thompson, D, Pepys, M.B, Wood, S.P.
Deposit date:1998-11-18
Release date:1999-12-03
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The physiological structure of human C-reactive protein and its complex with phosphocholine.
Structure Fold.Des., 7, 1999
2W08
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BU of 2w08 by Molmil
The structure of serum amyloid P component bound to 0-phospho- threonine
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, PHOSPHOTHREONINE, ...
Authors:Kolstoe, S.E, Pepys, M.B, Wood, S.P.
Deposit date:2008-08-12
Release date:2009-04-14
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Molecular Dissection of Alzheimer'S Disease Neuropathology by Depletion of Serum Amyloid P Component.
Proc.Natl.Acad.Sci.USA, 106, 2009
4FXL
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BU of 4fxl by Molmil
Crystal structure of the D76N Beta-2 Microglobulin mutant
Descriptor: ACETATE ION, Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, ...
Authors:Ricagno, S, Bellotti, V, Pepys, M.B, Stoppini, M, Bolognesi, M.
Deposit date:2012-07-03
Release date:2012-08-15
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Hereditary systemic amyloidosis due to Asp76Asn variant beta-2-microglobulin.
N.Engl.J.Med., 366, 2012
1GNH
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BU of 1gnh by Molmil
HUMAN C-REACTIVE PROTEIN
Descriptor: C-REACTIVE PROTEIN, CALCIUM ION
Authors:Shrive, A.K, Cheetham, G.M.T, Holden, D, Myles, D.A, Turnell, W.G, Volanakis, J.E, Pepys, M.B, Bloomer, A.C, Greenhough, T.J.
Deposit date:1996-03-01
Release date:1997-01-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Three dimensional structure of human C-reactive protein.
Nat.Struct.Biol., 3, 1996
1LGN
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BU of 1lgn by Molmil
DECAMERIC DAMP COMPLEX OF HUMAN SERUM AMYLOID P COMPONENT
Descriptor: 2'-DEOXYADENOSINE-5'-MONOPHOSPHATE, CALCIUM ION, SERUM AMYLOID P COMPONENT
Authors:Hohenester, E, Pepys, M.B, Wood, S.P.
Deposit date:1996-12-04
Release date:1997-12-24
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of a decameric complex of human serum amyloid P component with bound dAMP.
J.Mol.Biol., 269, 1997
1GYK
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BU of 1gyk by Molmil
Serum Amyloid P Component co-crystallised with MOBDG at neutral pH
Descriptor: CALCIUM ION, METHYL 4,6-O-[(1R)-1-CARBOXYETHYLIDENE]-BETA-D-GALACTOPYRANOSIDE, SERUM AMYLOID P-COMPONENT
Authors:Thompson, D, Pepys, M.B, Tickle, I, Wood, S.P.
Deposit date:2002-04-25
Release date:2003-05-22
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The Structures of Crystalline Complexes of Human Serum Amyloid P Component with its Carbohydrate Ligand, the Cyclic Pyruvate Acetal of Galactose
J.Mol.Biol., 320, 2002
3IPB
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BU of 3ipb by Molmil
Human Transthyretin (TTR) complexed with a palindromic bivalent amyloid inhibitor (11 carbon linker).
Descriptor: 2,2'-{undecane-1,11-diylbis[oxy(3,5-dichlorobenzene-4,1-diyl)imino]}dibenzoic acid, Transthyretin
Authors:Kolstoe, S.E, Wood, S.P, Pepys, M.B.
Deposit date:2009-08-17
Release date:2010-11-17
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Trapping of palindromic ligands within native transthyretin prevents amyloid formation.
Proc.Natl.Acad.Sci.USA, 107, 2010
3IPE
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BU of 3ipe by Molmil
Human Transthyretin (TTR) complexed with a palindromic bivalent amyloid inhibitor (7 carbon linker).
Descriptor: 2,2'-{heptane-1,7-diylbis[oxy(3,5-dichlorobenzene-4,1-diyl)imino]}dibenzoic acid, Transthyretin
Authors:Kolstoe, S.E, Wood, S.P, Pepys, M.B.
Deposit date:2009-08-17
Release date:2010-11-17
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Trapping of palindromic ligands within native transthyretin prevents amyloid formation.
Proc.Natl.Acad.Sci.USA, 107, 2010
3KQR
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BU of 3kqr by Molmil
The structure of serum amyloid p component bound to phosphoethanolamine
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, PHOSPHORIC ACID MONO-(2-AMINO-ETHYL) ESTER, ...
Authors:Mikolajek, H, Kolstoe, S.E, Wood, S.P, Pepys, M.B.
Deposit date:2009-11-17
Release date:2010-12-08
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural basis of ligand specificity in the human pentraxins, C-reactive protein and serum amyloid P component.
J.Mol.Recognit., 24, 2011
3L2Y
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BU of 3l2y by Molmil
The structure of C-reactive protein bound to phosphoethanolamine
Descriptor: C-reactive protein, CALCIUM ION, PHOSPHORIC ACID MONO-(2-AMINO-ETHYL) ESTER
Authors:Mikolajek, H, Kolstoe, S.E, Wood, S.P, Pepys, M.B.
Deposit date:2009-12-15
Release date:2010-12-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural basis of ligand specificity in the human pentraxins, C-reactive protein and serum amyloid P component.
J.Mol.Recognit., 24, 2011
2BX5
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BU of 2bx5 by Molmil
Is FR1 the antibody's Achillies heel
Descriptor: VD9 VKI LIGHT-CHAIN
Authors:James, L.C.
Deposit date:2005-07-22
Release date:2006-11-15
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Beta-Edge Interactions in a Pentadecameric Human Antibody Vkappa Domain.
J.Mol.Biol., 367, 2007
3M1O
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BU of 3m1o by Molmil
Human Transthyretin (TTR) complexed with 2-((3,5-dichloro-4-hydroxyphenyl)amino)benzoic acid
Descriptor: 2-[(3,5-dichloro-4-hydroxyphenyl)amino]benzoic acid, Transthyretin
Authors:Kolstoe, S.E, Wood, S.P.
Deposit date:2010-03-05
Release date:2010-11-17
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Trapping of palindromic ligands within native transthyretin prevents amyloid formation.
Proc.Natl.Acad.Sci.USA, 107, 2010
4AVV
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BU of 4avv by Molmil
Structure of CPHPC bound to Serum Amyloid P Component
Descriptor: (2R)-1-[6-[(2R)-2-carboxypyrrolidin-1-yl]-6-oxidanylidene-hexanoyl]pyrrolidine-2-carboxylic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Kolstoe, S.E, Jenvey, M.C, Wood, S.P.
Deposit date:2012-05-29
Release date:2013-06-19
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Interaction of Serum Amyloid P Component with Hexanoyl Bis(D-Proline) (Cphpc)
Acta Crystallogr.,Sect.D, 70, 2014
4AVS
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BU of 4avs by Molmil
Structure of N-Acetyl-L-Proline bound to Serum Amyloid P Component
Descriptor: 1-ACETYL-L-PROLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Kolstoe, S, Wood, S.P.
Deposit date:2012-05-29
Release date:2013-06-19
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.399 Å)
Cite:Interaction of Serum Amyloid P Component with Hexanoyl Bis(D-Proline) (Cphpc)
Acta Crystallogr.,Sect.D, 70, 2014
4AVT
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BU of 4avt by Molmil
Structure of CPHPC bound to Serum Amyloid P Component
Descriptor: (2R)-1-[6-[(2R)-2-carboxypyrrolidin-1-yl]-6-oxidanylidene-hexanoyl]pyrrolidine-2-carboxylic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Kolstoe, S.E, Purvis, A, Wood, S.P.
Deposit date:2012-05-29
Release date:2013-06-19
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Interaction of Serum Amyloid P Component with Hexanoyl Bis(D-Proline) (Cphpc)
Acta Crystallogr.,Sect.D, 70, 2014
4AYU
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BU of 4ayu by Molmil
Structure of N-Acetyl-D-Proline bound to serum amyloid P component
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, GLYCEROL, ...
Authors:Hughes, P, Kolstoe, S.E, Wood, S.P.
Deposit date:2012-06-22
Release date:2013-07-10
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Interaction of Serum Amyloid P Component with Hexanoyl Bis(D-Proline) (Cphpc)
Acta Crystallogr.,Sect.D, 70, 2014
4MRB
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BU of 4mrb by Molmil
Wild Type Human Transthyretin pH 7.5
Descriptor: CALCIUM ION, Transthyretin
Authors:Chen, W.J, Wood, S.P.
Deposit date:2013-09-17
Release date:2014-01-08
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.27 Å)
Cite:Proteolytic cleavage of Ser52Pro variant transthyretin triggers its amyloid fibrillogenesis.
Proc.Natl.Acad.Sci.USA, 111, 2014
4MRC
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BU of 4mrc by Molmil
Human Transthyretin Ser52Pro Mutant
Descriptor: CALCIUM ION, Transthyretin
Authors:Chen, W.J, Wood, S.P.
Deposit date:2013-09-17
Release date:2014-01-08
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:Proteolytic cleavage of Ser52Pro variant transthyretin triggers its amyloid fibrillogenesis.
Proc.Natl.Acad.Sci.USA, 111, 2014
1LOZ
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BU of 1loz by Molmil
AMYLOIDOGENIC VARIANT (I56T) VARIANT OF HUMAN LYSOZYME
Descriptor: LYSOZYME
Authors:Sunde, M, Blake, C.C.F.
Deposit date:1997-01-16
Release date:1997-04-01
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Instability, unfolding and aggregation of human lysozyme variants underlying amyloid fibrillogenesis.
Nature, 385, 1997
1LYY
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BU of 1lyy by Molmil
AMYLOIDOGENIC VARIANT (ASP67HIS) OF HUMAN LYSOZYME
Descriptor: LYSOZYME
Authors:Sunde, M, Blake, C.C.F.
Deposit date:1997-01-16
Release date:1997-04-01
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Instability, unfolding and aggregation of human lysozyme variants underlying amyloid fibrillogenesis.
Nature, 385, 1997
1QTJ
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BU of 1qtj by Molmil
CRYSTAL STRUCTURE OF LIMULUS POLYPHEMUS SAP
Descriptor: PROTEIN (SERUM AMYLOID P COMPONENT)
Authors:Shrive, A.K, Metcalfe, A.M, Cartwright, J.R, Greenhough, T.J.
Deposit date:1999-06-28
Release date:2000-06-28
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (3 Å)
Cite:C-reactive protein and SAP-like pentraxin are both present in Limulus polyphemus haemolymph: crystal structure of Limulus SAP.
J.Mol.Biol., 290, 1999

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