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4D0A
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BU of 4d0a by Molmil
3D EM map of the sodium proton antiporter MjNhaP1 from Methanocaldococcus jannaschii
Descriptor: NA(+)/H(+) ANTIPORTER 1
Authors:Paulino, C, Woehlert, D, Yildiz, O, Kuhlbrandt, W.
Deposit date:2014-04-25
Release date:2014-12-10
Last modified:2023-12-20
Method:ELECTRON CRYSTALLOGRAPHY (6 Å)
Cite:3D Em Map of the Sodium Proton Antiporter Mjnhap1 from Methanocaldococcus Jannaschii
Elife, 3, 2014
5NL2
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BU of 5nl2 by Molmil
cryo-EM structure of the mTMEM16A ion channel at 6.6 A resolution.
Descriptor: Anoctamin-1
Authors:Paulino, C, Neldner, Y, Lam, K.M, Kalienkova, V, Brunner, J.D, Schenck, S, Dutzler, R.
Deposit date:2017-04-03
Release date:2017-06-07
Last modified:2018-02-28
Method:ELECTRON MICROSCOPY (6.6 Å)
Cite:Structural basis for anion conduction in the calcium-activated chloride channel TMEM16A.
Elife, 6, 2017
5OYB
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BU of 5oyb by Molmil
Structure of calcium-bound mTMEM16A chloride channel at 3.75 A resolution
Descriptor: Anoctamin-1, CALCIUM ION
Authors:Paulino, C, Kalienkova, V, Lam, K.M, Neldner, Y, Dutzler, R.
Deposit date:2017-09-08
Release date:2017-12-20
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (3.75 Å)
Cite:Activation mechanism of the calcium-activated chloride channel TMEM16A revealed by cryo-EM.
Nature, 552, 2017
5OYG
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BU of 5oyg by Molmil
Structure of calcium-free mTMEM16A chloride channel at 4.06 A resolution
Descriptor: Anoctamin-1
Authors:Paulino, C, Kalienkova, V, Lam, K.M, Neldner, Y, Dutzler, R.
Deposit date:2017-09-08
Release date:2017-12-20
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (4.06 Å)
Cite:Activation mechanism of the calcium-activated chloride channel TMEM16A revealed by cryo-EM.
Nature, 552, 2017
4CZB
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BU of 4czb by Molmil
Structure of the sodium proton antiporter MjNhaP1 from Methanocaldococcus jannaschii at pH 8.
Descriptor: NA(+)/H(+) ANTIPORTER 1, POTASSIUM ION, TRIS(HYDROXYETHYL)AMINOMETHANE
Authors:Woehlert, D, Paulino, C, Kapotova, E, Kuhlbrandt, W, Yildiz, O.
Deposit date:2014-04-16
Release date:2014-12-10
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:3D Em Map of the Sodium Proton Antiporter Mjnhap1 from Methanocaldococcus Jannaschii
Elife, 3, 2014
7ZRI
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BU of 7zri by Molmil
Cryo-EM structure of the KdpFABC complex in a nucleotide-free E1 conformation loaded with K+
Descriptor: CARDIOLIPIN, POTASSIUM ION, Potassium-transporting ATPase ATP-binding subunit, ...
Authors:Hielkema, L, Stock, C, Silberberg, J.M, Corey, R.A, Wunnicke, D, Stansfeld, P.J, Haenelt, I, Paulino, C.
Deposit date:2022-05-04
Release date:2022-11-16
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Inhibited KdpFABC transitions into an E1 off-cycle state.
Elife, 11, 2022
7ZRM
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BU of 7zrm by Molmil
Cryo-EM map of the unphosphorylated KdpFABC complex in the E1-P_ADP conformation, under turnover conditions
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, POTASSIUM ION, ...
Authors:Hielkema, L, Stock, C, Silberberg, J.M, Corey, R.A, Wunnicke, D, Dubach, V.R.A, Stansfeld, P.J, Haenelt, I, Paulino, C.
Deposit date:2022-05-04
Release date:2022-11-16
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Inhibited KdpFABC transitions into an E1 off-cycle state.
Elife, 11, 2022
7ZRD
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BU of 7zrd by Molmil
Cryo-EM map of the WT KdpFABC complex in the E1-P tight conformation, stabilised with the inhibitor orthovanadate
Descriptor: CARDIOLIPIN, POTASSIUM ION, Potassium-transporting ATPase ATP-binding subunit, ...
Authors:Hielkema, L, Stock, C, Silberberg, J.M, Corey, R.A, Wunnicke, D, Stansfeld, P.J, Haenelt, I, Paulino, C.
Deposit date:2022-05-04
Release date:2022-11-16
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Inhibited KdpFABC transitions into an E1 off-cycle state.
Elife, 11, 2022
7ZRJ
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BU of 7zrj by Molmil
Cryo-EM structure of the KdpFABC complex in a nucleotide-free E1 conformation loaded with K+
Descriptor: CARDIOLIPIN, POTASSIUM ION, Potassium-transporting ATPase ATP-binding subunit, ...
Authors:Hielkema, L, Stock, C, Silberberg, J.M, Corey, R.A, Wunnicke, D, Stansfeld, P.J, Haenelt, I, Paulino, C.
Deposit date:2022-05-04
Release date:2022-11-16
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Inhibited KdpFABC transitions into an E1 off-cycle state.
Elife, 11, 2022
7ZRE
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BU of 7zre by Molmil
Cryo-EM map of the WT KdpFABC complex in the E1-P tight conformation, under turnover conditions
Descriptor: CARDIOLIPIN, POTASSIUM ION, Potassium-transporting ATPase ATP-binding subunit, ...
Authors:Hielkema, L, Stock, C, Silberberg, J.M, Corey, R.A, Wunnicke, D, Dubach, V.R.A, Stansfeld, P.J, Haenelt, I, Paulino, C.
Deposit date:2022-05-04
Release date:2022-11-16
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Inhibited KdpFABC transitions into an E1 off-cycle state.
Elife, 11, 2022
7ZRG
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BU of 7zrg by Molmil
Cryo-EM map of the WT KdpFABC complex in the E1_ATPearly conformation, under turnover conditions
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CARDIOLIPIN, POTASSIUM ION, ...
Authors:Hielkema, L, Stock, C, Silberberg, J.M, Corey, R.A, Rheinberger, J, Wunnicke, D, Dubach, V.R.A, Stansfeld, P.J, Haenelt, I, Paulino, C.
Deposit date:2022-05-04
Release date:2022-11-16
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Inhibited KdpFABC transitions into an E1 off-cycle state.
Elife, 11, 2022
7ZRK
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BU of 7zrk by Molmil
Cryo-EM map of the WT KdpFABC complex in the E1-P_ADP conformation, under turnover conditions
Descriptor: ADENOSINE-5'-DIPHOSPHATE, CARDIOLIPIN, POTASSIUM ION, ...
Authors:Hielkema, L, Stock, C, Silberberg, J.M, Corey, R.A, Wunnicke, D, Dubach, V.R.A, Stansfeld, P.J, Haenelt, I, Paulino, C.
Deposit date:2022-05-04
Release date:2022-11-16
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Inhibited KdpFABC transitions into an E1 off-cycle state.
Elife, 11, 2022
7ZRL
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BU of 7zrl by Molmil
Cryo-EM map of the unphosphorylated KdpFABC complex in the E2-P conformation, under turnover conditions
Descriptor: POTASSIUM ION, Potassium-transporting ATPase ATP-binding subunit, Potassium-transporting ATPase KdpC subunit, ...
Authors:Hielkema, L, Stock, C, Silberberg, J.M, Corey, R.A, Wunnicke, D, Dubach, V.R.A, Stansfeld, P.J, Haenelt, I, Paulino, C.
Deposit date:2022-05-04
Release date:2022-11-16
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Inhibited KdpFABC transitions into an E1 off-cycle state.
Elife, 11, 2022
7ZRH
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BU of 7zrh by Molmil
Cryo-EM structure of the KdpFABC complex in a nucleotide-free E1 conformation loaded with K+
Descriptor: CARDIOLIPIN, POTASSIUM ION, Potassium-transporting ATPase ATP-binding subunit, ...
Authors:Hielkema, L, Stock, C, Silberberg, J.M, Corey, R.A, Wunnicke, D, Stansfeld, P.J, Haenelt, I, Paulino, C.
Deposit date:2022-05-04
Release date:2022-11-16
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Inhibited KdpFABC transitions into an E1 off-cycle state.
Elife, 11, 2022
7NNP
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BU of 7nnp by Molmil
Rb-loaded cryo-EM structure of the E1-ATP KdpFABC complex.
Descriptor: CARDIOLIPIN, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, Potassium-transporting ATPase ATP-binding subunit, ...
Authors:Silberberg, J.M, Corey, R.A, Hielkema, L, Stock, C, Stansfeld, P.J, Paulino, C, Haenelt, I.
Deposit date:2021-02-25
Release date:2021-07-28
Last modified:2021-09-29
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Deciphering ion transport and ATPase coupling in the intersubunit tunnel of KdpFABC.
Nat Commun, 12, 2021
7NNL
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BU of 7nnl by Molmil
Cryo-EM structure of the KdpFABC complex in an E1-ATP conformation loaded with K+
Descriptor: CARDIOLIPIN, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, POTASSIUM ION, ...
Authors:Silberberg, J.M, Corey, R.A, Hielkema, L, Stock, C, Stansfeld, P.J, Paulino, C, Haenelt, I.
Deposit date:2021-02-25
Release date:2021-07-28
Last modified:2021-09-29
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Deciphering ion transport and ATPase coupling in the intersubunit tunnel of KdpFABC.
Nat Commun, 12, 2021
6GCT
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BU of 6gct by Molmil
cryo-EM structure of the human neutral amino acid transporter ASCT2
Descriptor: GLUTAMINE, Neutral amino acid transporter B(0)
Authors:Garaeva, A.A, Oostergetel, G.T, Gati, C, Guskov, A, Paulino, C, Slotboom, D.J.
Deposit date:2018-04-19
Release date:2018-06-13
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (3.85 Å)
Cite:Cryo-EM structure of the human neutral amino acid transporter ASCT2.
Nat. Struct. Mol. Biol., 25, 2018
7P78
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BU of 7p78 by Molmil
SARS-CoV-2 spike protein in complex with sybody#15 and sybody#68 in a 1up/1up-out/1down conformation
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(5-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Walter, J.D, Hutter, C.A.J, Garaeva, A.A, Scherer, M, Zimmermann, I, Wyss, M, Rheinberger, J, Ruedin, Y, Earp, J.C, Egloff, P, Sorgenfrei, M, Huerlimann, L.M, Gonda, I, Meier, G, Remm, S, Thavarasah, S, Zimmer, G, Slotboom, D.J, Paulino, C, Plattet, P, Seeger, M.A.
Deposit date:2021-07-19
Release date:2021-08-04
Last modified:2022-04-20
Method:ELECTRON MICROSCOPY (3.32 Å)
Cite:Biparatopic sybodies neutralize SARS-CoV-2 variants of concern and mitigate drug resistance.
Embo Rep., 23, 2022
7P79
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BU of 7p79 by Molmil
SARS-CoV-2 spike protein in complex with sybodyb#15 in a 1up/1up-out/1down conformation.
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(5-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Walter, J.D, Hutter, C.A.J, Garaeva, A.A, Scherer, M, Zimmermann, I, Wyss, M, Rheinberger, J, Ruedin, Y, Earp, J.C, Egloff, P, Sorgenfrei, M, Huerlimann, L.M, Gonda, I, Meier, G, Remm, S, Thavarasah, S, Zimmer, G, Slotboom, D.J, Paulino, C, Plattet, P, Seeger, M.A.
Deposit date:2021-07-19
Release date:2021-08-04
Last modified:2022-04-20
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Biparatopic sybodies neutralize SARS-CoV-2 variants of concern and mitigate drug resistance.
Embo Rep., 23, 2022
7P7A
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BU of 7p7a by Molmil
SARS-CoV-2 spike protein in complex with sybody#68 in a 2up/1flexible conformation
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(5-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Walter, J.D, Hutter, C.A.J, Garaeva, A.A, Scherer, M, Zimmermann, I, Wyss, M, Rheinberger, J, Ruedin, Y, Earp, J.C, Egloff, P, Sorgenfrei, M, Huerlimann, L.M, Gonda, I, Meier, G, Remm, S, Thavarasah, S, Zimmer, G, Slotboom, D.J, Paulino, C, Plattet, P, Seeger, M.A.
Deposit date:2021-07-19
Release date:2021-08-04
Last modified:2022-04-20
Method:ELECTRON MICROSCOPY (4.76 Å)
Cite:Biparatopic sybodies neutralize SARS-CoV-2 variants of concern and mitigate drug resistance.
Embo Rep., 23, 2022
7P7B
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BU of 7p7b by Molmil
SARS-CoV-2 spike protein in complex with sybody no68 in a 1up/2down conformation
Descriptor: Spike glycoprotein
Authors:Walter, J.D, Hutter, C.A.J, Garaeva, A.A, Scherer, M, Zimmermann, I, Wyss, M, Rheinberger, J, Ruedin, Y, Earp, J.C, Egloff, P, Sorgenfrei, M, Huerlimann, L.M, Gonda, I, Meier, G, Remm, S, Thavarasah, S, Zimmer, G, Slotboom, D.J, Paulino, C, Plattet, P, Seeger, M.A.
Deposit date:2021-07-19
Release date:2021-08-04
Last modified:2022-04-20
Method:ELECTRON MICROSCOPY (3.13 Å)
Cite:Biparatopic sybodies neutralize SARS-CoV-2 variants of concern and mitigate drug resistance.
Embo Rep., 23, 2022
7P77
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BU of 7p77 by Molmil
SARS-CoV-2 spike protein in complex with sybody#15 and sybody#68 in a 3up conformation
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(5-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Walter, J.D, Hutter, C.A.J, Garaeva, A.A, Scherer, M, Zimmermann, I, Wyss, M, Rheinberger, J, Ruedin, Y, Earp, J.C, Egloff, P, Sorgenfrei, M, Huerlimann, L.M, Gonda, I, Meier, G, Remm, S, Thavarasah, S, Zimmer, G, Slotboom, D.J, Paulino, C, Plattet, P, Seeger, M.A.
Deposit date:2021-07-19
Release date:2021-08-04
Last modified:2022-04-20
Method:ELECTRON MICROSCOPY (2.98 Å)
Cite:Biparatopic sybodies neutralize SARS-CoV-2 variants of concern and mitigate drug resistance.
Embo Rep., 23, 2022
6HRA
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BU of 6hra by Molmil
Cryo-EM structure of the KdpFABC complex in an E1 outward-facing state (state 1)
Descriptor: POTASSIUM ION, Potassium-transporting ATPase ATP-binding subunit, Potassium-transporting ATPase KdpC subunit, ...
Authors:Stock, C, Hielkema, L, Tascon, I, Wunnicke, D, Oostergetel, G.T, Azkargorta, M, Paulino, C, Haenelt, I.
Deposit date:2018-09-26
Release date:2018-12-05
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Cryo-EM structures of KdpFABC suggest a K+transport mechanism via two inter-subunit half-channels.
Nat Commun, 9, 2018
6HRB
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BU of 6hrb by Molmil
Cryo-EM structure of the KdpFABC complex in an E2 inward-facing state (state 2)
Descriptor: POTASSIUM ION, Potassium-transporting ATPase ATP-binding subunit, Potassium-transporting ATPase KdpC subunit, ...
Authors:Stock, C, Hielkema, L, Tascon, I, Wunnicke, D, Oostergetel, G.T, Azkargorta, M, Paulino, C, Haenelt, I.
Deposit date:2018-09-26
Release date:2018-12-05
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Cryo-EM structures of KdpFABC suggest a K+transport mechanism via two inter-subunit half-channels.
Nat Commun, 9, 2018
8BMP
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BU of 8bmp by Molmil
Cryo-EM structure of the folate-specific ECF transporter complex in MSP2N2 lipid nanodiscs bound to ATP and ADP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Energy-coupling factor transporter ATP-binding protein EcfA1, ...
Authors:Thangaratnarajah, C, Rheinberger, J, Paulino, C, Slotboom, D.J.
Deposit date:2022-11-10
Release date:2023-08-02
Last modified:2023-08-09
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Expulsion mechanism of the substrate-translocating subunit in ECF transporters.
Nat Commun, 14, 2023

 

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