1COL
| REFINED STRUCTURE OF THE PORE-FORMING DOMAIN OF COLICIN A AT 2.4 ANGSTROMS RESOLUTION | Descriptor: | COLICIN A | Authors: | Parker, M.W, Postma, J.P.M, Pattus, F, Tucker, A.D, Tsernoglou, D. | Deposit date: | 1991-07-06 | Release date: | 1992-07-15 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Refined structure of the pore-forming domain of colicin A at 2.4 A resolution. J.Mol.Biol., 224, 1992
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1Z52
| Proaerolysin Mutant W373L | Descriptor: | Aerolysin | Authors: | Parker, M.W, Feil, S.C, Tang, J.W. | Deposit date: | 2005-03-16 | Release date: | 2006-03-07 | Last modified: | 2021-11-10 | Method: | X-RAY DIFFRACTION (2.38 Å) | Cite: | Crystal Structure of Proaerolysin at 2.3 A Resolution and Structural Analyses of Single-site Mutants as a Basis for Understanding Membrane Insertion of the Toxin To be Published
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1PRE
| PROAEROLYSIN | Descriptor: | PROAEROLYSIN | Authors: | Parker, M.W, Buckley, J.T, Postma, J.P.M, Tucker, A.D, Tsernoglou, D. | Deposit date: | 1995-09-15 | Release date: | 1996-10-14 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structure of the Aeromonas toxin proaerolysin in its water-soluble and membrane-channel states. Nature, 367, 1994
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5DIM
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5DHL
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4QDQ
| Physical basis for Nrp2 ligand binding | Descriptor: | GLYCEROL, Neuropilin-2, SULFATE ION | Authors: | Parker, M.W, Vander Kooi, C.W. | Deposit date: | 2014-05-14 | Release date: | 2015-04-15 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structural Basis for VEGF-C Binding to Neuropilin-2 and Sequestration by a Soluble Splice Form. Structure, 23, 2015
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4QDR
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4QDS
| Physical basis for Nrp2 ligand binding | Descriptor: | ACETATE ION, GLYCEROL, Neuropilin-2 | Authors: | Parker, M.W, Vander Kooi, C.W. | Deposit date: | 2014-05-14 | Release date: | 2015-04-15 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural Basis for VEGF-C Binding to Neuropilin-2 and Sequestration by a Soluble Splice Form. Structure, 23, 2015
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4NKQ
| Structure of a Cytokine Receptor Complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Cytokine receptor common subunit beta, Granulocyte-macrophage colony-stimulating factor, ... | Authors: | Parker, M.W, Broughton, S.E. | Deposit date: | 2013-11-13 | Release date: | 2015-09-23 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (3.301 Å) | Cite: | Conformational Changes in the GM-CSF Receptor Suggest a Molecular Mechanism for Affinity Conversion and Receptor Signaling. Structure, 24, 2016
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4ZGH
| Structure of Sugar Binding Protein Pneumolysin | Descriptor: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, GOLD (I) CYANIDE ION, ... | Authors: | Parker, M.W, Feil, S.C, Morton, C. | Deposit date: | 2015-04-23 | Release date: | 2016-03-09 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Crystal structure of Streptococcus pneumoniae pneumolysin provides key insights into early steps of pore formation. Sci Rep, 5, 2015
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1D5S
| CRYSTAL STRUCTURE OF CLEAVED ANTITRYPSIN POLYMER | Descriptor: | P1-ARG ANTITRYPSIN | Authors: | Dunstone, M.A, Dai, W, Whisstock, J.C, Rossjohn, J, Pike, R.N, Feil, S.C, Le Bonneic, B.F, Parker, M.W, Bottomley, S.P. | Deposit date: | 1999-10-11 | Release date: | 2000-04-02 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Cleaved antitrypsin polymers at atomic resolution. Protein Sci., 9, 2000
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6XD4
| CDC-like protein | Descriptor: | ACETATE ION, Hemolysin, SODIUM ION | Authors: | Morton, C.J, Parker, M.W, Lawrence, S.L, Johnstone, B.A, Tweten, R.K. | Deposit date: | 2020-06-09 | Release date: | 2021-04-21 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | A Key Motif in the Cholesterol-Dependent Cytolysins Reveals a Large Family of Related Proteins. Mbio, 11, 2020
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1ZGN
| Crystal Structure of the Glutathione Transferase Pi in Complex with Dinitrosyl-diglutathionyl Iron Complex | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, FE (III) ION, GLUTATHIONE, ... | Authors: | Parker, L.J, Adams, J.J, Parker, M.W. | Deposit date: | 2005-04-21 | Release date: | 2005-11-01 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Nitrosylation of human glutathione transferase P1-1 with dinitrosyl diglutathionyl iron complex in vitro and in vivo J.Biol.Chem., 280, 2005
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4TKX
| Structure of Protease | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, LEAD (II) ION, ... | Authors: | Gorman, M.A, Parker, M.W. | Deposit date: | 2014-05-28 | Release date: | 2014-12-31 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structure of the lysine specific protease Kgp from Porphyromonas gingivalis, a target for improved oral health. Protein Sci., 24, 2015
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4RS1
| Crystal structure of receptor-cytokine complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Granulocyte-macrophage colony-stimulating factor, ... | Authors: | Broughton, S.E, Parker, M.W, Dhagat, U. | Deposit date: | 2014-11-06 | Release date: | 2015-11-11 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.68 Å) | Cite: | Conformational Changes in the GM-CSF Receptor Suggest a Molecular Mechanism for Affinity Conversion and Receptor Signaling. Structure, 24, 2016
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1Z0M
| the glycogen-binding domain of the AMP-activated protein kinase beta1 subunit | Descriptor: | 5'-AMP-activated protein kinase, beta-1 subunit, Cycloheptakis-(1-4)-(alpha-D-glucopyranose) | Authors: | Polekhina, G, Gupta, A, van Denderen, B.J, Feil, S.C, Kemp, B.E, Stapleton, D, Parker, M.W. | Deposit date: | 2005-03-02 | Release date: | 2005-10-25 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.91 Å) | Cite: | Structural Basis for Glycogen Recognition by AMP-Activated Protein Kinase. Structure, 13, 2005
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1Z0N
| the glycogen-binding domain of the AMP-activated protein kinase | Descriptor: | 5'-AMP-activated protein kinase, beta-1 subunit, Cycloheptakis-(1-4)-(alpha-D-glucopyranose) | Authors: | Polekhina, G, Gupta, A, van Denderen, B.J, Feil, S.C, Kemp, B.E, Stapleton, D, Parker, M.W. | Deposit date: | 2005-03-02 | Release date: | 2005-10-25 | Last modified: | 2021-11-10 | Method: | X-RAY DIFFRACTION (1.49 Å) | Cite: | Structural Basis for Glycogen Recognition by AMP-Activated Protein Kinase. Structure, 13, 2005
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5DCG
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5DAL
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5DAK
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19GS
| Glutathione s-transferase p1-1 | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 3,3'-(4,5,6,7-TETRABROMO-3-OXO-1(3H)-ISOBENZOFURANYLIDENE)BIS [6-HYDROXYBENZENESULFONIC ACID]ANION, GLUTATHIONE, ... | Authors: | Oakley, A.J, Lo Bello, M, Parker, M.W. | Deposit date: | 1997-12-14 | Release date: | 1998-12-30 | Last modified: | 2023-08-02 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | The ligandin (non-substrate) binding site of human Pi class glutathione transferase is located in the electrophile binding site (H-site). J.Mol.Biol., 291, 1999
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1A87
| COLICIN N | Descriptor: | COLICIN N | Authors: | Vetter, I.R, Parker, M.W, Tucker, A.D, Lakey, J.H, Pattus, F, Tsernoglou, D. | Deposit date: | 1998-04-03 | Release date: | 1999-04-06 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Crystal structure of a colicin N fragment suggests a model for toxicity. Structure, 6, 1998
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2A2R
| Crystal Structure of Glutathione Transferase Pi in complex with S-nitrosoglutathione | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-AMINO-5-[1-(CARBOXYLATOMETHYLCARBAMOYL)-2-NITROSOSULFANYL-ETHYL]AMINO-5-OXO-PENTANOATE, CALCIUM ION, ... | Authors: | Parker, L.J, Morton, C.J, Adams, J.J, Parker, M.W. | Deposit date: | 2005-06-23 | Release date: | 2006-06-06 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Calorimetric and structural studies of the nitric oxide carrier S-nitrosoglutathione bound to human glutathione transferase P1-1 Protein Sci., 15, 2006
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2A2S
| Crystal Structure of Human Glutathione Transferase in complex with S-nitrosoglutathione in the absence of reducing agent | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-AMINO-5-[1-(CARBOXYLATOMETHYLCARBAMOYL)-2-NITROSOSULFANYL-ETHYL]AMINO-5-OXO-PENTANOATE, CALCIUM ION, ... | Authors: | Parker, L.J, Morton, C.J, Adams, J.J, Parker, M.W. | Deposit date: | 2005-06-23 | Release date: | 2006-06-06 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Calorimetric and structural studies of the nitric oxide carrier S-nitrosoglutathione bound to human glutathione transferase P1-1 Protein Sci., 15, 2006
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6PRO
| MnSOD from Geobacillus stearothermophilus | Descriptor: | MANGANESE (II) ION, Superoxide dismutase | Authors: | Adams, J.J, Morton, C.J, Parker, M.W. | Deposit date: | 2019-07-10 | Release date: | 2020-05-20 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.263 Å) | Cite: | The Crystal Structure of the Manganese Superoxide Dismutase from Geobacillus stearothermophilus: Parker and Blake (1988) Revisited Aust.J.Chem., 73, 2020
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