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1PTS
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CRYSTAL STRUCTURE AND LIGAND BINDING STUDIES OF A SCREENED PEPTIDE COMPLEXED WITH STREPTAVIDIN
Descriptor:STREPTAVIDIN, PEPTIDE (FSHPQNT)
Authors:Weber, P.C., Pantoliano, M.W., Thompson, L.D.
Deposit date:1992-07-23
Release date:1994-01-31
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure and ligand-binding studies of a screened peptide complexed with streptavidin.
Biochemistry, 31, 1992
1R42
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NATIVE HUMAN ANGIOTENSIN CONVERTING ENZYME-RELATED CARBOXYPEPTIDASE (ACE2)
Descriptor:angiotensin I converting enzyme 2, disordered segment of collectrin homology domain, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Towler, P., Staker, B., Prasad, S.G., Menon, S., Ryan, D., Tang, J., Parsons, T., Fisher, M., Williams, D., Dales, N.A., Patane, M.A., Pantoliano, M.W.
Deposit date:2003-10-07
Release date:2004-02-03
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:ACE2 X-ray structures reveal a large hinge-bending motion important for inhibitor binding and catalysis.
J.Biol.Chem., 279, 2004
1R4L
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INHIBITOR BOUND HUMAN ANGIOTENSIN CONVERTING ENZYME-RELATED CARBOXYPEPTIDASE (ACE2)
Descriptor:angiotensin I converting enzyme 2, disordered segment of collectrin homology domain, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Towler, P., Staker, B., Prasad, S.G., Menon, S., Ryan, D., Tang, J., Parsons, T., Fisher, M., Williams, D., Dales, N.A., Patane, M.A., Pantoliano, M.W.
Deposit date:2003-10-07
Release date:2004-02-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:ACE2 X-ray structures reveal a large hinge-bending motion important for inhibitor binding and catalysis.
J.Biol.Chem., 279, 2004
1S01
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LARGE INCREASES IN GENERAL STABILITY FOR SUBTILISIN BPN(PRIME) THROUGH INCREMENTAL CHANGES IN THE FREE ENERGY OF UNFOLDING
Descriptor:Subtilisin BPN', CALCIUM ION, ISOPROPYL ALCOHOL
Authors:Whitlow, M., Howard, A.J., Wood, J.F.
Deposit date:1989-08-21
Release date:1990-10-15
Last modified:2018-02-14
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Large increases in general stability for subtilisin BPN' through incremental changes in the free energy of unfolding.
Biochemistry, 28, 1989
1AK9
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SUBTILISIN MUTANT 8321
Descriptor:SUBTILISIN 8321, CALCIUM ION, SODIUM ION, ...
Authors:Whitlow, M., Howard, A.J., Wood, J.F.
Deposit date:1997-05-30
Release date:1997-11-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Large increases in general stability for subtilisin BPN' through incremental changes in the free energy of unfolding.
Biochemistry, 28, 1989
1AU9
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SUBTILISIN BPN' MUTANT 8324 IN CITRATE
Descriptor:SUBTILISIN BPN', CALCIUM ION, UNKNOWN ATOM OR ION, ...
Authors:Whitlow, M., Howard, A.J., Wood, J.F.
Deposit date:1997-09-12
Release date:1997-12-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Large increases in general stability for subtilisin BPN' through incremental changes in the free energy of unfolding.
Biochemistry, 28, 1989
1A2Q
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SUBTILISIN BPN' MUTANT 7186
Descriptor:SUBTILISIN BPN', CALCIUM ION, ACETONE
Authors:Gilliland, G.L., Whitlow, M., Howard, A.J.
Deposit date:1998-01-08
Release date:1998-04-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Large increases in general stability for subtilisin BPN' through incremental changes in the free energy of unfolding.
Biochemistry, 28, 1989
1AQN
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SUBTILISIN MUTANT 8324
Descriptor:SUBTILISIN 8324, CALCIUM ION, UNKNOWN ATOM OR ION, ...
Authors:Whitlow, M., Howard, A.J., Wood, J.F.
Deposit date:1997-07-31
Release date:1998-01-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Large increases in general stabilityfor subtilisin BPN' through incremental changes in the free energy of unfolding
To be published
1SRF
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STRUCTURE-BASED DESIGN OF SYNTHETIC AZOBENZENE LIGANDS FOR STREPTAVIDIN
Descriptor:STREPTAVIDIN, 2-((3'-TERTBUTYL-4'-HYDROXYPHENYL)AZO)BENZOIC ACID
Authors:Weber, P.C., Salemme, F.R.
Deposit date:1994-02-17
Release date:1994-11-01
Last modified:2012-10-10
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure-Based Design of Synthetic Azobenzene Ligands for Streptavidin
J.Am.Chem.Soc., 116, 1994
1SRG
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STRUCTURE-BASED DESIGN OF SYNTHETIC AZOBENZENE LIGANDS FOR STREPTAVIDIN
Descriptor:STREPTAVIDIN, 2-((3'-METHYL-4'-HYDROXYPHENYL)AZO)BENZOIC ACID
Authors:Weber, P.C., Salemme, F.R.
Deposit date:1994-02-17
Release date:1994-12-20
Last modified:2012-10-10
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure-Based Design of Synthetic Azobenzene Ligands for Streptavidin
J.Am.Chem.Soc., 116, 1994
1SRH
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STRUCTURE-BASED DESIGN OF SYNTHETIC AZOBENZENE LIGANDS FOR STREPTAVIDIN
Descriptor:STREPTAVIDIN, 2-((3',5'-DIMETHOXY-4'-HYDROXYPHENYL)AZO)BENZOIC ACID
Authors:Weber, P.C., Salemme, F.R.
Deposit date:1994-02-17
Release date:1994-11-01
Last modified:2012-10-10
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure-Based Design of Synthetic Azobenzene Ligands for Streptavidin
J.Am.Chem.Soc., 116, 1994
1SRI
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STRUCTURE-BASED DESIGN OF SYNTHETIC AZOBENZENE LIGANDS FOR STREPTAVIDIN
Descriptor:STREPTAVIDIN, 2-((3',5'-DIMETHYL-4'-HYDROXYPHENYL)AZO)BENZOIC ACID
Authors:Weber, P.C., Salemme, F.R.
Deposit date:1994-02-17
Release date:1994-11-01
Last modified:2012-10-10
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structure-Based Design of Synthetic Azobenzene Ligands for Streptavidin
J.Am.Chem.Soc., 116, 1994
1SRJ
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STRUCTURE-BASED DESIGN OF SYNTHETIC AZOBENZENE LIGANDS FOR STREPTAVIDIN
Descriptor:STREPTAVIDIN, 2-((4'-HYDROXYNAPHTHYL)-AZO)BENZOIC ACID
Authors:Weber, P.C., Salemme, F.R.
Deposit date:1994-02-17
Release date:1994-11-01
Last modified:2012-10-10
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure-Based Design of Synthetic Azobenzene Ligands for Streptavidin
J.Am.Chem.Soc., 116, 1994
1SRE
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CRYSTALLOGRAPHIC AND THERMODYNAMIC COMPARISON OF NATURAL AND SYNTHETIC LIGANDS BOUND TO STREPTAVIDIN
Descriptor:STREPTAVIDIN, 2-((4'-HYDROXYPHENYL)-AZO)BENZOIC ACID
Authors:Weber, P.C., Salemme, F.R.
Deposit date:1994-02-17
Release date:1994-11-01
Last modified:2012-10-10
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Structure-Based Design of Synthetic Azobenzene Ligands for Streptavidin
J.Am.Chem.Soc., 116, 1994
1STP
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STRUCTURAL ORIGINS OF HIGH-AFFINITY BIOTIN BINDING TO STREPTAVIDIN
Descriptor:STREPTAVIDIN COMPLEX WITH BIOTIN, BIOTIN
Authors:Weber, P.C., Salemme, F.R.
Deposit date:1992-03-12
Release date:1992-10-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural origins of high-affinity biotin binding to streptavidin.
Science, 243, 1989