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4DQO
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BU of 4dqo by Molmil
Crystal Structure of PG16 Fab in Complex with V1V2 Region from HIV-1 strain ZM109
Descriptor: 1FD6-V1V2 scaffold ZM109 HIV-1 strain, N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, PG16 Fab Heavy Chain, ...
Authors:Pancera, M, McLellan, J.S, Kwong, P.D.
Deposit date:2012-02-16
Release date:2013-03-06
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.438 Å)
Cite:Structural basis for diverse N-glycan recognition by HIV-1-neutralizing V1-V2-directed antibody PG16.
Nat.Struct.Mol.Biol., 20, 2013
3MME
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BU of 3mme by Molmil
Structure and functional dissection of PG16, an antibody with broad and potent neutralization of HIV-1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, PG16 HEAVY CHAIN FAB, ...
Authors:Pancera, M, McLellan, J, Zhou, T, Zhu, J, Kwong, P.
Deposit date:2010-04-19
Release date:2010-06-09
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.97 Å)
Cite:Crystal structure of PG16 and chimeric dissection with somatically related PG9: structure-function analysis of two quaternary-specific antibodies that effectively neutralize HIV-1.
J.Virol., 84, 2010
4TVP
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BU of 4tvp by Molmil
Crystal Structure of the HIV-1 BG505 SOSIP.664 Env Trimer Ectodomain, Comprising Atomic-Level Definition of Pre-Fusion gp120 and gp41, in Complex with Human Antibodies PGT122 and 35O22
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 35O22 Heavy chain, ...
Authors:Pancera, M, Zhou, T, Kwong, P.D.
Deposit date:2014-06-27
Release date:2014-10-08
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structure and immune recognition of trimeric pre-fusion HIV-1 Env.
Nature, 514, 2014
3JWO
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BU of 3jwo by Molmil
Structure of HIV-1 gp120 with gp41-Interactive Region: Layered Architecture and Basis of Conformational Mobility
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, FAB 48D Heavy CHAIN, FAB 48D LIGHT CHAIN, ...
Authors:Pancera, M, Majeed, S, Huang, C.C, Kwon, Y.D, Zhou, T, Robinson, J.E, Sodroski, J, Wyatt, R, Kwong, P.D.
Deposit date:2009-09-18
Release date:2009-12-29
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.51 Å)
Cite:Structure of HIV-1 gp120 with gp41-interactive region reveals layered envelope architecture and basis of conformational mobility.
Proc.Natl.Acad.Sci.USA, 107, 2010
3JWD
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BU of 3jwd by Molmil
Structure of HIV-1 gp120 with gp41-Interactive Region: Layered Architecture and Basis of Conformational Mobility
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, FAB 48D HEAVY CHAIN, FAB 48D LIGHT CHAIN, ...
Authors:Pancera, M, Majeed, S, Ban, Y.A, Chen, L, Huang, C.C, Kong, L, Kwon, Y.D, Stuckey, J, Zhou, T, Robinson, J.E, Schief, W.R, Sodroski, J, Wyatt, R, Kwong, P.D.
Deposit date:2009-09-18
Release date:2009-12-29
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.61 Å)
Cite:Structure of HIV-1 gp120 with gp41-interactive region reveals layered envelope architecture and basis of conformational mobility.
Proc.Natl.Acad.Sci.USA, 107, 2010
3LRS
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BU of 3lrs by Molmil
Structure of PG16, an antibody with broad and potent neutralization of HIV-1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, PG-16 Heavy Chain Fab, PG-16 Light Chain Fab
Authors:Pancera, M, Kwong, P.D.
Deposit date:2010-02-11
Release date:2010-06-09
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.37 Å)
Cite:Crystal structure of PG16 and chimeric dissection with somatically related PG9: structure-function analysis of two quaternary-specific antibodies that effectively neutralize HIV-1.
J.Virol., 84, 2010
5U7O
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BU of 5u7o by Molmil
Crystal Structure of HIV-1 BG505 SOSIP.664 Prefusion Env Trimer Bound to Small Molecule HIV-1 Entry Inhibitor BMS-626529 in Complex with Human Antibodies PGT122 and 35O22 at 3.8 Angstrom
Descriptor: 1-[4-(benzenecarbonyl)piperazin-1-yl]-2-[4-methoxy-7-(3-methyl-1H-1,2,4-triazol-1-yl)-1H-pyrrolo[2,3-c]pyridin-3-yl]ethane-1,2-dione, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Pancera, M, Lai, Y.-T, Kwong, P.D.
Deposit date:2016-12-12
Release date:2017-08-30
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3.031 Å)
Cite:Crystal structures of trimeric HIV envelope with entry inhibitors BMS-378806 and BMS-626529.
Nat. Chem. Biol., 13, 2017
5U7M
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BU of 5u7m by Molmil
Crystal Structure of HIV-1 BG505 SOSIP.664 Prefusion Env Trimer Bound to Small Molecule HIV-1 Entry Inhibitor BMS-378806 in Complex with Human Antibodies PGT122 and 35O22 at 3.8 Angstrom
Descriptor: 1-[(2R)-4-(benzenecarbonyl)-2-methylpiperazin-1-yl]-2-(4-methoxy-1H-pyrrolo[2,3-b]pyridin-3-yl)ethane-1,2-dione, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Pancera, M, Lai, Y.-T, Kwong, P.D.
Deposit date:2016-12-12
Release date:2017-08-30
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3.025 Å)
Cite:Crystal structures of trimeric HIV envelope with entry inhibitors BMS-378806 and BMS-626529.
Nat. Chem. Biol., 13, 2017
4TOY
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BU of 4toy by Molmil
Structure of 35O22 Fab, a HIV-1 neutralizing antibody
Descriptor: 35O22 Fab Heavy chain, 35O22 Fab Light chain
Authors:Pancera, M, Kwong, P.D.
Deposit date:2014-06-06
Release date:2014-09-03
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.551 Å)
Cite:Broad and potent HIV-1 neutralization by a human antibody that binds the gp41-gp120 interface.
Nature, 515, 2014
5UTF
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BU of 5utf by Molmil
Crystal Structure of a Stabilized DS-SOSIP.6mut BG505 gp140 HIV-1 Env Trimer, Containing Mutations I201C-P433C (DS), L154M, Y177W, N300M, N302M, T320L, I420M in Complex with Human Antibodies PGT122 and 35O22 at 4.3 A
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 35022 Heavy chain, ...
Authors:Pancera, M, Chuang, G.-Y, Xu, K, Kwong, P.D.
Deposit date:2017-02-14
Release date:2017-03-29
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.503 Å)
Cite:Structure-Based Design of a Soluble Prefusion-Closed HIV-1 Env Trimer with Reduced CD4 Affinity and Improved Immunogenicity.
J. Virol., 91, 2017
3U4B
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BU of 3u4b by Molmil
CH04H/CH02L Fab P4
Descriptor: CH02 Light chain, CH04 Heavy chain
Authors:Pancera, M, Louder, R, Mclellan, J.S, KWong, P.D.
Deposit date:2011-10-07
Release date:2011-11-30
Last modified:2011-12-21
Method:X-RAY DIFFRACTION (2.893 Å)
Cite:Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9.
Nature, 480, 2011
6B5P
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BU of 6b5p by Molmil
Structure of PfCSP peptide 20 with human antibody CIS42
Descriptor: CIS42 Fab Heavy chain, CIS42 Fab Light chain, pfCSP peptide 20: ASN-PRO-ASP-PRO-ASN-ALA-ASN-PRO-ASN-VAL-ASP
Authors:Pancera, M, Weidle, C.
Deposit date:2017-09-29
Release date:2018-03-21
Last modified:2018-04-25
Method:X-RAY DIFFRACTION (2.297 Å)
Cite:A human monoclonal antibody prevents malaria infection by targeting a new site of vulnerability on the parasite.
Nat. Med., 24, 2018
6B5R
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BU of 6b5r by Molmil
Structure of PfCSP peptide 21 with human antibody CIS42
Descriptor: CIS42 Fab Heavy chain, CIS42 Fab Light chain, PfCSP peptide 21: ASN-PRO-ASP-PRO-ASN-ALA-ASN-PRO-ASN-VAL-ASP-PRO-ASN
Authors:Pancera, M, Weidle, C.
Deposit date:2017-09-29
Release date:2018-03-21
Last modified:2018-04-25
Method:X-RAY DIFFRACTION (1.775 Å)
Cite:A human monoclonal antibody prevents malaria infection by targeting a new site of vulnerability on the parasite.
Nat. Med., 24, 2018
6B5M
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BU of 6b5m by Molmil
Structure of PfCSP peptide 21 with human protective antibody CIS43
Descriptor: 1,2-ETHANEDIOL, CIS43 Fab Heavy chain, CIS43 Fab Light chain, ...
Authors:Pancera, M, Weidle, C.
Deposit date:2017-09-29
Release date:2018-03-21
Last modified:2018-04-25
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:A human monoclonal antibody prevents malaria infection by targeting a new site of vulnerability on the parasite.
Nat. Med., 24, 2018
6B5T
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BU of 6b5t by Molmil
Structure of PfCSP peptide 29 with human antibody CIS42
Descriptor: AMMONIUM ION, CIS42 Fab Heavy chain, CIS42 Fab Light chain, ...
Authors:Pancera, M, Weidle, C.
Deposit date:2017-09-29
Release date:2018-03-21
Last modified:2018-04-25
Method:X-RAY DIFFRACTION (2.222 Å)
Cite:A human monoclonal antibody prevents malaria infection by targeting a new site of vulnerability on the parasite.
Nat. Med., 24, 2018
6B5N
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BU of 6b5n by Molmil
Structure of PfCSP peptide 25 with human protective antibody CIS43
Descriptor: CIS43 Fab Heavy chain, CIS43 Fab Light chain, pfCSP peptide 25: ASN-VAL-ASP-PRO-ASN-ALA-ASN-PRO-ASN-VAL-ASP
Authors:Pancera, M, Weidle, C.
Deposit date:2017-09-29
Release date:2018-03-21
Last modified:2018-04-25
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:A human monoclonal antibody prevents malaria infection by targeting a new site of vulnerability on the parasite.
Nat. Med., 24, 2018
6B5O
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BU of 6b5o by Molmil
Structure of PfCSP peptide 29 with human protective antibody CIS43
Descriptor: CIS43 Fab Heavy chain, CIS43 Fab Light chain, PfCSP peptide 29: ASN-PRO-ASN-ALA-ASN-PRO-ASN-ALA-ASN
Authors:Pancera, M, Weidle, C.
Deposit date:2017-09-29
Release date:2018-03-21
Last modified:2018-04-25
Method:X-RAY DIFFRACTION (2.194 Å)
Cite:A human monoclonal antibody prevents malaria infection by targeting a new site of vulnerability on the parasite.
Nat. Med., 24, 2018
6B5L
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BU of 6b5l by Molmil
Structure of PfCSP peptide 20 with human protective antibody CIS43
Descriptor: CIS43 Fab Heavy chain, CIS43 Fab Light Chain, PfCSP peptide 20: ASN-PRO-ASP-PRO-ASN-ALA-ASN-PRO-ASN-VAL
Authors:Pancera, M, Weidle, C.
Deposit date:2017-09-29
Release date:2018-03-21
Last modified:2018-04-25
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:A human monoclonal antibody prevents malaria infection by targeting a new site of vulnerability on the parasite.
Nat. Med., 24, 2018
6B5S
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BU of 6b5s by Molmil
Structure of PfCSP peptide 25 with human antibody CIS42
Descriptor: AMMONIUM ION, CIS42 Fab Heavy chain, CIS42 Fab Light chain, ...
Authors:Pancera, M, Weidle, C.
Deposit date:2017-09-29
Release date:2018-03-21
Last modified:2019-01-09
Method:X-RAY DIFFRACTION (1.983 Å)
Cite:A human monoclonal antibody prevents malaria infection by targeting a new site of vulnerability on the parasite.
Nat. Med., 24, 2018
5TF1
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BU of 5tf1 by Molmil
Structure of chimeric 02-CC Fab, a VRC01-like germline antibody
Descriptor: 02-CC Fab Heavy chain, O2-CC Fab Light Chain
Authors:Pancera, M.
Deposit date:2016-09-23
Release date:2016-11-16
Last modified:2019-12-11
Method:X-RAY DIFFRACTION (1.858 Å)
Cite:Differences in Allelic Frequency and CDRH3 Region Limit the Engagement of HIV Env Immunogens by Putative VRC01 Neutralizing Antibody Precursors.
Cell Rep, 17, 2016
5TGB
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BU of 5tgb by Molmil
Structure of chimeric 02-CB Fab, a VRC01-like germline antibody
Descriptor: 02-CB Fab Heavy Chain, 02-CB Fab Light Chain
Authors:Pancera, M.
Deposit date:2016-09-27
Release date:2016-11-09
Last modified:2019-12-11
Method:X-RAY DIFFRACTION (2.741 Å)
Cite:Differences in Allelic Frequency and CDRH3 Region Limit the Engagement of HIV Env Immunogens by Putative VRC01 Neutralizing Antibody Precursors.
Cell Rep, 17, 2016
5TFS
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BU of 5tfs by Molmil
Structure of chimeric 02-K Fab, a VRC01-like germline antibody
Descriptor: 02-K Fab Heavy chain, 02-K Fab Light chain, SULFATE ION
Authors:Pancera, M.
Deposit date:2016-09-26
Release date:2016-11-09
Last modified:2019-12-11
Method:X-RAY DIFFRACTION (2.319 Å)
Cite:Differences in Allelic Frequency and CDRH3 Region Limit the Engagement of HIV Env Immunogens by Putative VRC01 Neutralizing Antibody Precursors.
Cell Rep, 17, 2016
6BLA
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BU of 6bla by Molmil
Structure of AMM01 Fab, an anti EBV gH/gL neutralizing antibody
Descriptor: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, AMM01 Fab Heavy chain, ...
Authors:Pancera, M, Weidle, C, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2017-11-09
Release date:2018-04-25
Last modified:2019-11-13
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:An Antibody Targeting the Fusion Machinery Neutralizes Dual-Tropic Infection and Defines a Site of Vulnerability on Epstein-Barr Virus.
Immunity, 48, 2018
6C5V
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BU of 6c5v by Molmil
An anti-gH/gL antibody that neutralizes dual-tropic infection defines a site of vulnerability on Epstein-Barr virus
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody Fab AMMO1 heavy chain, Antibody Fab AMMO1 light chain, ...
Authors:Snijder, J, Ortego, M.S, Weidle, C, Stuart, A.B, Gray, M.A, McElrath, M.J, Pancera, M, Veesler, D, McGuire, A.T, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2018-01-16
Release date:2018-05-02
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (4.8 Å)
Cite:An Antibody Targeting the Fusion Machinery Neutralizes Dual-Tropic Infection and Defines a Site of Vulnerability on Epstein-Barr Virus.
Immunity, 48, 2018
6U9U
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BU of 6u9u by Molmil
Structure of GM9_TH8seq732127 FAB
Descriptor: 1,2-ETHANEDIOL, FORMIC ACID, GM9_TH8seq732127 FAB heavy chain, ...
Authors:Singh, S, Liban, T.J, Pancera, M.
Deposit date:2019-09-09
Release date:2019-11-06
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:Extensive dissemination and intraclonal maturation of HIV Env vaccine-induced B cell responses.
J.Exp.Med., 217, 2020

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