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2XQQ
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HUMAN DYNEIN LIGHT CHAIN (DYNLL2) IN COMPLEX WITH AN IN VITRO EVOLVED PEPTIDE (AC-SRGTQTE).
Descriptor:DYNEIN LIGHT CHAIN 2, CYTOPLASMIC, SAC-ARG-GLY-THR-GLN-THR-GLU, ...
Authors:Rapali, P., Radnai, L., Suveges, D., Hetenyi, C., Harmat, V., Tolgyesi, F., Wahlgren, W.Y., Katona, G., Nyitray, L., Pal, G.
Deposit date:2010-09-07
Release date:2011-05-04
Last modified:2019-03-06
Method:X-RAY DIFFRACTION (1.31 Å)
Cite:Directed Evolution Reveals the Binding Motif Preference of the Lc8/Dynll Hub Protein and Predicts Large Numbers of Novel Binders in the Human Proteome
Plos One, 6, 2011
2XTT
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BOVINE TRYPSIN IN COMPLEX WITH EVOLUTIONARY ENHANCED SCHISTOCERCA GREGARIA PROTEASE INHIBITOR 1 (SGPI-1-P02)
Descriptor:PROTEASE INHIBITOR SGPI-1, CATIONIC TRYPSIN, CALCIUM ION, ...
Authors:Wahlgren, W.Y., Pal, G., Kardos, J., Porrogi, P., Szenthe, B., Patthy, A., Graf, L., Katona, G.
Deposit date:2010-10-12
Release date:2010-11-10
Last modified:2017-07-12
Method:X-RAY DIFFRACTION (0.93 Å)
Cite:The Catalytic Aspartate is Protonated in the Michaelis Complex Formed between Trypsin and an in Vitro Evolved Substrate-Like Inhibitor: A Refined Mechanism of Serine Protease Action.
J.Biol.Chem., 286, 2011
3P8M
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HUMAN DYNEIN LIGHT CHAIN (DYNLL2) IN COMPLEX WITH AN IN VITRO EVOLVED PEPTIDE DIMERIZED BY LEUCINE ZIPPER
Descriptor:Dynein light chain 2, General control protein GCN4
Authors:Rapali, P., Radnai, L., Suveges, D., Hetenyi, C., Harmat, V., Tolgyesi, F., Wahlgren, W.Y., Katona, G., Nyitray, L., Pal, G.
Deposit date:2010-10-14
Release date:2011-08-31
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Directed evolution reveals the binding motif preference of the LC8/DYNLL hub protein and predicts large numbers of novel binders in the human proteome.
Plos One, 6, 2011
3TVJ
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CATALYTIC FRAGMENT OF MASP-2 IN COMPLEX WITH ITS SPECIFIC INHIBITOR DEVELOPED BY DIRECTED EVOLUTION ON SGCI SCAFFOLD
Descriptor:Mannan-binding lectin serine protease 2 A chain, Mannan-binding lectin serine protease 2 B chain, Protease inhibitor SGPI-2, ...
Authors:Heja, D., Harmat, V., Dobo, J., Szasz, R., Kekesi, K.A., Zavodszky, P., Gal, P., Pal, G.
Deposit date:2011-09-20
Release date:2012-04-25
Last modified:2012-06-27
Method:X-RAY DIFFRACTION (1.28 Å)
Cite:Monospecific Inhibitors Show That Both Mannan-binding Lectin-associated Serine Protease-1 (MASP-1) and -2 Are Essential for Lectin Pathway Activation and Reveal Structural Plasticity of MASP-2.
J.Biol.Chem., 287, 2012
4DJZ
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CATALYTIC FRAGMENT OF MASP-1 IN COMPLEX WITH ITS SPECIFIC INHIBITOR DEVELOPED BY DIRECTED EVOLUTION ON SGCI SCAFFOLD
Descriptor:Mannan-binding lectin serine protease 1 heavy chain, Mannan-binding lectin serine protease 1 light chain, Protease inhibitor SGPI-2
Authors:Heja, D., Harmat, V., Fodor, K., Wilmanns, M., Dobo, J., Kekesi, K.A., Zavodszky, P., Gal, P., Pal, G.
Deposit date:2012-02-03
Release date:2012-04-25
Last modified:2012-06-27
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Monospecific Inhibitors Show That Both Mannan-binding Lectin-associated Serine Protease-1 (MASP-1) and -2 Are Essential for Lectin Pathway Activation and Reveal Structural Plasticity of MASP-2.
J.Biol.Chem., 287, 2012
2B59
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THE TYPE II COHESIN DOCKERIN COMPLEX
Descriptor:COG1196: Chromosome segregation ATPases, Cellulosomal scaffolding protein A, CALCIUM ION
Authors:Adams, J.J., Smith, S.P., Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI)
Deposit date:2005-09-27
Release date:2005-10-11
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.11 Å)
Cite:Mechanism of bacterial cell-surface attachment revealed by the structure of cellulosomal type II cohesin-dockerin complex.
Proc.Natl.Acad.Sci.Usa, 103, 2006
4IGD
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CRYSTAL STRUCTURE OF THE ZYMOGEN CATALYTIC REGION OF HUMAN MASP-1
Descriptor:Mannan-binding lectin serine protease 1, GLYCEROL
Authors:Harmat, V., Megyeri, M., Vegh, A., Dobo, J.
Deposit date:2012-12-17
Release date:2013-02-13
Last modified:2013-07-10
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Quantitative characterization of the activation steps of mannan-binding lectin (MBL)-associated serine proteases (MASPs) points to the central role of MASP-1 in the initiation of the complement lectin pathway
J.Biol.Chem., 288, 2013