Author results

1MHE
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THE HUMAN NON-CLASSICAL MAJOR HISTOCOMPATIBILITY COMPLEX MOLECULE HLA-E
Descriptor:HLA CLASS I HISTOCOMPATIBILITY ANTIGEN HLA-E, BETA-2-MICROGLOBULIN, PEPTIDE (VMAPRTVLL), ...
Authors:O'Callaghan, C.A., Tormo, J., Willcox, B.E., Braud, V.B., Jakobsen, B.K., Stuart, D.I., Mcmichael, A.J., Bell, J.I., Jones, E.Y.
Deposit date:1998-08-24
Release date:1999-03-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Structural features impose tight peptide binding specificity in the nonclassical MHC molecule HLA-E.
Mol.Cell, 1, 1998
1AGB
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ANTAGONIST HIV-1 GAG PEPTIDES INDUCE STRUCTURAL CHANGES IN HLA B8-HIV-1 GAG PEPTIDE (GGRKKYKL-3R MUTATION)
Descriptor:B*0801, BETA-2 MICROGLOBULIN, HIV-1 GAG PEPTIDE (GGRKKYKL - 3R MUTATION)
Authors:Reid, S.W., Mcadam, S., Smith, K.J., Klenerman, P., O'Callaghan, C.A., Harlos, K., Jakobsen, B.K., Mcmichael, A.J., Bell, J., Stuart, D.I., Jones, E.Y.
Deposit date:1997-03-24
Release date:1997-06-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Antagonist HIV-1 Gag peptides induce structural changes in HLA B8.
J.Exp.Med., 184, 1996
1AGC
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ANTAGONIST HIV-1 GAG PEPTIDES INDUCE STRUCTURAL CHANGES IN HLA B8-HIV-1 GAG PEPTIDE (GGKKKYQL-7Q MUTATION)
Descriptor:B*0801, BETA-2 MICROGLOBULIN, HIV-1 GAG PEPTIDE (GGKKKYQL - 7Q MUTATION)
Authors:Reid, S.W., Mcadam, S., Smith, K.J., Klenerman, P., O'Callaghan, C.A., Harlos, K., Jakobsen, B.K., Mcmichael, A.J., Bell, J., Stuart, D.I., Jones, E.Y.
Deposit date:1997-03-24
Release date:1997-06-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Antagonist HIV-1 Gag peptides induce structural changes in HLA B8.
J.Exp.Med., 184, 1996
1AGD
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ANTAGONIST HIV-1 GAG PEPTIDES INDUCE STRUCTURAL CHANGES IN HLA B8-HIV-1 GAG PEPTIDE (GGKKKYKL-INDEX PEPTIDE)
Descriptor:B*0801, BETA-2 MICROGLOBULIN, HIV-1 GAG PEPTIDE (GGKKKYKL - INDEX PEPTIDE)
Authors:Reid, S.W., Mcadam, S., Smith, K.J., Klenerman, P., O'Callaghan, C.A., Harlos, K., Jakobsen, B.K., Mcmichael, A.J., Bell, J., Stuart, D.I., Jones, E.Y.
Deposit date:1997-03-24
Release date:1997-06-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Antagonist HIV-1 Gag peptides induce structural changes in HLA B8.
J.Exp.Med., 184, 1996
1AGE
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ANTAGONIST HIV-1 GAG PEPTIDES INDUCE STRUCTURAL CHANGES IN HLA B8-HIV-1 GAG PEPTIDE (GGKKKYRL-7R MUTATION)
Descriptor:B*0801, BETA-2 MICROGLOBULIN, HIV-1 GAG PEPTIDE (GGKKKYRL - 7R MUTATION)
Authors:Reid, S.W., Mcadam, S., Smith, K.J., Klenerman, P., O'Callaghan, C.A., Harlos, K., Jakobsen, B.K., Mcmichael, A.J., Bell, J., Stuart, D.I., Jones, E.Y.
Deposit date:1997-03-24
Release date:1997-06-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Antagonist HIV-1 Gag peptides induce structural changes in HLA B8.
J.Exp.Med., 184, 1996
1AGF
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ANTAGONIST HIV-1 GAG PEPTIDES INDUCE STRUCTURAL CHANGES IN HLA B8-HIV-1 GAG PEPTIDE (GGKKRYKL-5R MUTATION)
Descriptor:B*0801, BETA-2 MICROGLOBULIN, HIV-1 GAG PEPTIDE (GGKKRYKL - 5R MUTATION)
Authors:Reid, S.W., Mcadam, S., Smith, K.J., Klenerman, P., O'Callaghan, C.A., Harlos, K., Jakobsen, B.K., Mcmichael, A.J., Bell, J., Stuart, D.I., Jones, E.Y.
Deposit date:1997-03-24
Release date:1997-06-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Antagonist HIV-1 Gag peptides induce structural changes in HLA B8.
J.Exp.Med., 184, 1996
2BPD
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STRUCTURE OF MURINE DECTIN-1
Descriptor:DECTIN-1
Authors:Brown, J., O'Callaghan, C.A., Marshall, A.S.J., Gilbert, R.J.C., Siebold, C., Gordon, S., Brown, G.D., Jones, E.Y.
Deposit date:2005-04-19
Release date:2006-08-30
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structure of the Fungal Beta-Glucan-Binding Immune Receptor Dectin-1: Implications for Function.
Protein Sci., 16, 2007
2BPE
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STRUCTURE OF MURINE DECTIN-1
Descriptor:DECTIN-1, CALCIUM ION, CHLORIDE ION, ...
Authors:Brown, J., O'Callaghan, C.A., Marshall, A.S.J., Gilbert, R.J.C., Siebold, C., Gordon, S., Brown, G.D., Jones, E.Y.
Deposit date:2005-04-19
Release date:2006-08-31
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structure of the Fungal Beta-Glucan-Binding Immune Receptor Dectin-1: Implications for Function.
Protein Sci., 16, 2007
2BPH
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STRUCTURE OF MURINE DECTIN-1
Descriptor:DECTIN-1, MAGNESIUM ION
Authors:Brown, J., O'Callaghan, C.A., Marshall, A.S.J., Gilbert, R.J.C., Siebold, C., Gordon, S., Brown, G.D., Jones, E.Y.
Deposit date:2005-04-19
Release date:2006-08-31
Last modified:2019-04-10
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of the Fungal Beta-Glucan-Binding Immune Receptor Dectin-1: Implications for Function.
Protein Sci., 16, 2007
2C6U
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CRYSTAL STRUCTURE OF HUMAN CLEC-2 (CLEC1B)
Descriptor:CLEC1B PROTEIN
Authors:Watson, A.A., Brown, J., O'Callaghan, C.A.
Deposit date:2005-11-11
Release date:2006-11-20
Last modified:2017-07-12
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:The Crystal Structure and Mutational Binding Analysis of the Extracellular Domain of the Platelet-Activating Receptor Clec-2.
J.Biol.Chem., 282, 2007
2CIK
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INSIGHTS INTO CROSSREACTIVITY IN HUMAN ALLORECOGNITION: THE STRUCTURE OF HLA-B35011 PRESENTING AN EPITOPE DERIVED FROM CYTOCHROME P450.
Descriptor:HLA CLASS I HISTOCOMPATIBILITY ANTIGEN B-35 ALPHA CHAIN, BETA-2-MICROGLOBULIN, PEPTIDE, ...
Authors:Hourigan, C.S., Harkiolaki, M., Peterson, N.A., Bell, J.I., Jones, E.Y., O'Callaghan, C.A.
Deposit date:2006-03-22
Release date:2006-10-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:The Structure of the Human Allo-Ligand Hla-B3501 in Complex with a Cytochrome P450 Peptide: Steric Hindrance Influences Tcr Allo-Recognition.
Eur.J.Immunol., 36, 2006
2CL8
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DECTIN-1 IN COMPLEX WITH BETA-GLUCAN
Descriptor:DECTIN-1, CALCIUM ION, CHLORIDE ION, ...
Authors:Brown, J., O'Callaghan, C.A., Marshall, A.S.J., Gilbert, R.J.C., Siebold, C., Gordon, S., Brown, G.D., Jones, E.Y.
Deposit date:2006-04-26
Release date:2007-05-15
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of the Fungal Beta-Glucan-Binding Immune Receptor Dectin-1: Implications for Function.
Protein Sci., 16, 2007
2VRP
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STRUCTURE OF RHODOCYTIN
Descriptor:AGGRETIN ALPHA CHAIN, AGGRETIN BETA CHAIN, SODIUM ION, ...
Authors:Watson, A.A., O'Callaghan, C.A.
Deposit date:2008-04-09
Release date:2008-07-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.41 Å)
Cite:Crystal Structure of Rhodocytin, a Ligand for the Platelet-Activating Receptor Clec-2.
Protein Sci., 17, 2008
2WFQ
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CRYSTAL STRUCTURE OF THE N-TERMINAL SIGNALLING DOMAIN OF HUMAN DHH WITHOUT CALCIUM
Descriptor:DESERT HEDGEHOG PROTEIN N-PRODUCT, ZINC ION, SULFATE ION
Authors:Bishop, B., Aricescu, A.R., Harlos, K., O'Callaghan, C.A., Jones, E.Y., Siebold, C.
Deposit date:2009-04-14
Release date:2009-06-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural Insights Into Hedgehog Ligand Sequestration by the Human Hedgehog-Interacting Protein Hip
Nat.Struct.Mol.Biol., 16, 2009
2WFR
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CRYSTAL STRUCTURE OF THE N-TERMINAL SIGNALLING DOMAIN OF HUMAN DHH WITH CALCIUM
Descriptor:DESERT HEDGEHOG PROTEIN N-PRODUCT, ZINC ION, CALCIUM ION, ...
Authors:Bishop, B., Aricescu, A.R., Harlos, K., O'Callaghan, C.A., Jones, E.Y., Siebold, C.
Deposit date:2009-04-14
Release date:2009-06-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural Insights Into Hedgehog Ligand Sequestration by the Human Hedgehog-Interacting Protein Hip
Nat.Struct.Mol.Biol., 16, 2009
2WFT
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CRYSTAL STRUCTURE OF THE HUMAN HIP ECTODOMAIN
Descriptor:HEDGEHOG-INTERACTING PROTEIN, SODIUM ION, CHLORIDE ION
Authors:Bishop, B., Aricescu, A.R., Harlos, K., O'Callaghan, C.A., Jones, E.Y., Siebold, C.
Deposit date:2009-04-15
Release date:2009-06-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural Insights Into Hedgehog Ligand Sequestration by the Human Hedgehog-Interacting Protein Hip
Nat.Struct.Mol.Biol., 16, 2009
2WFX
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CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN HUMAN HEDGEHOG-INTERACTING PROTEIN HIP AND SONIC HEDGEHOG IN THE PRESENCE OF CALCIUM
Descriptor:SONIC HEDGEHOG PROTEIN N-PRODUCT, HEDGEHOG-INTERACTING PROTEIN, ZINC ION, ...
Authors:Bishop, B., Aricescu, A.R., Harlos, K., O'Callaghan, C.A., Jones, E.Y., Siebold, C.
Deposit date:2009-04-15
Release date:2009-06-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural Insights Into Hedgehog Ligand Sequestration by the Human Hedgehog-Interacting Protein Hip
Nat.Struct.Mol.Biol., 16, 2009
2WG3
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CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN HUMAN HEDGEHOG-INTERACTING PROTEIN HIP AND DESERT HEDGEHOG WITHOUT CALCIUM
Descriptor:DESERT HEDGEHOG PROTEIN N-PRODUCT, HEDGEHOG-INTERACTING PROTEIN, ZINC ION, ...
Authors:Bishop, B., Aricescu, A.R., Harlos, K., O'Callaghan, C.A., Jones, E.Y., Siebold, C.
Deposit date:2009-04-15
Release date:2009-06-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural Insights Into Hedgehog Ligand Sequestration by the Human Hedgehog-Interacting Protein Hip
Nat.Struct.Mol.Biol., 16, 2009
2WG4
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CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN HUMAN HEDGEHOG-INTERACTING PROTEIN HIP AND SONIC HEDGEHOG WITHOUT CALCIUM
Descriptor:SONIC HEDGEHOG PROTEIN N-PRODUCT, HEDGEHOG-INTERACTING PROTEIN, ZINC ION, ...
Authors:Bishop, B., Aricescu, A.R., Harlos, K., O'Callaghan, C.A., Jones, E.Y., Siebold, C.
Deposit date:2009-04-15
Release date:2009-06-30
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Structural Insights Into Hedgehog Ligand Sequestration by the Human Hedgehog-Interacting Protein Hip
Nat.Struct.Mol.Biol., 16, 2009
2YHF
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1.9 ANGSTROM CRYSTAL STRUCTURE OF CLEC5A
Descriptor:C-TYPE LECTIN DOMAIN FAMILY 5 MEMBER A
Authors:Watson, A.A., Lebedev, A.A., Murshudov, G.M., Vagin, A.A., Hall, B.A., O'Callaghan, C.A.
Deposit date:2011-04-30
Release date:2011-05-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural Flexibility of the Macrophage Dengue Virus Receptor Clec5A: Implications for Ligand Binding and Signaling.
J.Biol.Chem., 286, 2011
6GGM
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HLA-E*01:03 IN COMPLEX WITH THE MTB44 PEPTIDE VARIANT: MTB44*P2-PHE.
Descriptor:MHC class I antigen, Beta-2-microglobulin, Mtb44*P2-Phe peptide variant (ARG-PHE-PRO-ALA-LYS-ALA-PRO-LEU-LEU), ...
Authors:Walters, L.C., Gillespie, G.M., McMichael, A.J., Rozbesky, D., Jones, E.Y., Harlos, K.
Deposit date:2018-05-03
Release date:2018-08-08
Last modified:2018-08-22
Method:X-RAY DIFFRACTION (2.734 Å)
Cite:Pathogen-derived HLA-E bound epitopes reveal broad primary anchor pocket tolerability and conformationally malleable peptide binding.
Nat Commun, 9, 2018
6GH1
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HLA-E*01:03 IN COMPLEX WITH MTB44
Descriptor:MHC class I antigen, Beta-2-microglobulin, Enoyl-[acyl-carrier-protein] reductase [NADH], ...
Authors:Walters, L.C., Gillespie, G.M., McMichael, A.J., Rozbesky, D., Jones, E.Y., Harlos, K.
Deposit date:2018-05-04
Release date:2018-08-08
Last modified:2018-08-22
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Pathogen-derived HLA-E bound epitopes reveal broad primary anchor pocket tolerability and conformationally malleable peptide binding.
Nat Commun, 9, 2018
6GH4
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HLA-E*01:03 IN COMPLEX WITH THE MTB44 PEPTIDE VARIANT: MTB44*P2-GLN.
Descriptor:MHC class I antigen, Beta-2-microglobulin, ARG-GLN-PRO-ALA-LYS-ALA-PRO-LEU-LEU, ...
Authors:Walters, L.C., Gillespie, G.M., McMichael, A.J., Rozbesky, D., Jones, E.Y., Harlos, K.
Deposit date:2018-05-04
Release date:2018-08-08
Last modified:2018-08-22
Method:X-RAY DIFFRACTION (2.16 Å)
Cite:Pathogen-derived HLA-E bound epitopes reveal broad primary anchor pocket tolerability and conformationally malleable peptide binding.
Nat Commun, 9, 2018
6GHN
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HLA-E*01:03 IN COMPLEX WITH THE MTB44 PEPTIDE VARIANT: MTB44*P9-PHE.
Descriptor:HLA class I histocompatibility antigen, E alpha chain variant, Beta-2-microglobulin, ...
Authors:Walters, L.C., Gillespie, G.M., McMichael, A.J., Rozbesky, D., Jones, E.Y., Harlos, K.
Deposit date:2018-05-08
Release date:2018-08-08
Last modified:2018-08-22
Method:X-RAY DIFFRACTION (2.542 Å)
Cite:Pathogen-derived HLA-E bound epitopes reveal broad primary anchor pocket tolerability and conformationally malleable peptide binding.
Nat Commun, 9, 2018
6GL1
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HLA-E*01:03 IN COMPLEX WITH THE HIV EPITOPE, RL9HIV
Descriptor:MHC class I antigen, Beta-2-microglobulin, ARG-MET-TYR-SER-PRO-THR-SER-ILE-LEU, ...
Authors:Walters, L.C., Gillespie, G.M., McMichael, A.J., Rozbesky, D., Jones, E.Y., Harlos, K.
Deposit date:2018-05-22
Release date:2018-08-08
Last modified:2018-08-22
Method:X-RAY DIFFRACTION (2.623 Å)
Cite:Pathogen-derived HLA-E bound epitopes reveal broad primary anchor pocket tolerability and conformationally malleable peptide binding.
Nat Commun, 9, 2018