Author results

4PP6
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CRYSTAL STRUCTURE OF THE ESTROGEN RECEPTOR ALPHA LIGAND-BINDING DOMAIN IN COMPLEX WITH RESVERATROL
Descriptor:Estrogen receptor, Nuclear receptor coactivator 2, RESVERATROL
Authors:Nwachukwu, J.C., Srinivasan, S., Bruno, N.E., Parent, A.A., Hughes, T.S., Pollock, J.A., Gjyshi, O., Cavett, V., Nowak, J., Garcia-Ordonez, R.D., Houtman, R., Griffin, P.R., Kojetin, D.J., Katzenellenbogen, J.A., Conkright, M.D., Nettles, K.W.
Deposit date:2014-02-26
Release date:2014-05-07
Last modified:2014-06-11
Method:X-RAY DIFFRACTION (2.201 Å)
Cite:Resveratrol modulates the inflammatory response via an estrogen receptor-signal integration network.
Elife, 3, 2014
4PPP
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CRYSTAL STRUCTURE OF THE ESTROGEN RECEPTOR ALPHA LIGAND-BINDING DOMAIN IN COMPLEX WITH FLUORO-RESVERATROL
Descriptor:Estrogen receptor, Nuclear receptor coactivator 2, 5-[(E)-2-(3-fluoro-4-hydroxyphenyl)ethenyl]benzene-1,3-diol
Authors:Nwachukwu, J.C., Srinivasan, S., Bruno, N.E., Parent, A.A., Hughes, T.S., Pollock, J.A., Gjyshi, O., Cavett, V., Nowak, J., Garcia-Ordonez, R.D., Houtman, R., Griffin, P.R., Kojetin, D.J., Katzenellenbogen, J.A., Conkright, M.D., Nettles, K.W.
Deposit date:2014-02-27
Release date:2014-05-07
Last modified:2014-06-11
Method:X-RAY DIFFRACTION (2.686 Å)
Cite:Resveratrol modulates the inflammatory response via an estrogen receptor-signal integration network.
Elife, 3, 2014
4PPS
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CRYSTAL STRUCTURE OF THE ESTROGEN RECEPTOR ALPHA LIGAND-BINDING DOMAIN IN COMPLEX WITH AN A-CD RING ESTROGEN DERIVATIVE
Descriptor:Estrogen receptor, Nuclear receptor coactivator 2, (1S,3aR,5R,7aS)-5-(4-hydroxyphenyl)-7a-methyloctahydro-1H-inden-1-ol
Authors:Nwachukwu, J.C., Srinivasan, S., Bruno, N.E., Parent, A.A., Hughes, T.S., Pollock, J.A., Gjyshi, O., Cavett, V., Nowak, J., Garcia-Ordonez, R.D., Houtman, R., Griffin, P.R., Kojetin, D.J., Katzenellenbogen, J.A., Conkright, M.D., Nettles, K.W.
Deposit date:2014-02-27
Release date:2014-05-07
Last modified:2014-06-11
Method:X-RAY DIFFRACTION (1.929 Å)
Cite:Resveratrol modulates the inflammatory response via an estrogen receptor-signal integration network.
Elife, 3, 2014
4ZN7
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CRYSTAL STRUCTURE OF THE ER-ALPHA LIGAND-BINDING DOMAIN (Y537S) IN COMPLEX WITH DIETHYLSTILBESTROL
Descriptor:Estrogen receptor, Nuclear receptor coactivator 2, DIETHYLSTILBESTROL
Authors:Nwachukwu, J.C., Srinivasan, S., Zheng, Y., Wang, S., Min, J., Dong, C., Liao, Z., Cavett, V., Nowak, J., Houtman, R., Carlson, K.E., Josan, J.S., Elemento, O., Katzenellenbogen, J.A., Zhou, H.B., Nettles, K.W.
Deposit date:2015-05-04
Release date:2016-05-04
Method:X-RAY DIFFRACTION (1.934 Å)
Cite:Predictive features of ligand-specific signaling through the estrogen receptor.
Mol.Syst.Biol., 12, 2016
4ZNH
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CRYSTAL STRUCTURE OF THE ER-ALPHA LIGAND-BINDING DOMAIN (Y537S) IN COMPLEX WITH A 2-FLUORO-SUBSTITUTED OBHS DERIVATIVE
Descriptor:Estrogen receptor, Nuclear receptor-interacting peptide, 2-fluorophenyl (1S,2R,4S)-5,6-bis(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hept-5-ene-2-sulfonate
Authors:Nwachukwu, J.C., Srinivasan, S., Zheng, Y., Wang, S., Min, J., Dong, C., Liao, Z., Cavett, V., Nowak, J., Houtman, R., Carlson, K.E., Josan, J.S., Elemento, O., Katzenellenbogen, J.A., Zhou, H.B., Nettles, K.W.
Deposit date:2015-05-04
Release date:2016-05-04
Last modified:2016-07-20
Method:X-RAY DIFFRACTION (1.933 Å)
Cite:Predictive features of ligand-specific signaling through the estrogen receptor.
Mol.Syst.Biol., 12, 2016
4ZNS
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CRYSTAL STRUCTURE OF THE ER-ALPHA LIGAND-BINDING DOMAIN (Y537S) IN COMPLEX WITH A 3-FLUORO-SUBSTITUTED OBHS DERIVATIVE
Descriptor:Estrogen receptor, Nuclear receptor-interacting peptide, 3-fluorophenyl (1S,2R,4S)-5,6-bis(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hept-5-ene-2-sulfonate
Authors:Nwachukwu, J.C., Srinivasan, S., Zheng, Y., Wang, S., Min, J., Dong, C., Liao, Z., Cavett, V., Nowak, J., Houtman, R., Carlson, K.E., Josan, J.S., Elemento, O., Katzenellenbogen, J.A., Zhou, H.B., Nettles, K.W.
Deposit date:2015-05-05
Release date:2016-05-04
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Predictive features of ligand-specific signaling through the estrogen receptor.
Mol.Syst.Biol., 12, 2016
4ZNT
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CRYSTAL STRUCTURE OF THE ER-ALPHA LIGAND-BINDING DOMAIN (Y537S) IN COMPLEX WITH A 3-BROMO-SUBSTITUTED OBHS DERIVATIVE
Descriptor:Estrogen receptor, Nuclear receptor-interacting peptide, 3-bromophenyl (1S,2R,4S)-5,6-bis(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hept-5-ene-2-sulfonate
Authors:Nwachukwu, J.C., Srinivasan, S., Zheng, Y., Wang, S., Min, J., Dong, C., Liao, Z., Cavett, V., Nowak, J., Houtman, R., Carlson, K.E., Josan, J.S., Elemento, O., Katzenellenbogen, J.A., Zhou, H.B., Nettles, K.W.
Deposit date:2015-05-05
Release date:2016-05-04
Method:X-RAY DIFFRACTION (1.903 Å)
Cite:Predictive features of ligand-specific signaling through the estrogen receptor.
Mol.Syst.Biol., 12, 2016
4ZNU
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CRYSTAL STRUCTURE OF THE ER-ALPHA LIGAND-BINDING DOMAIN (Y537S) IN COMPLEX WITH A 2-METHYL-SUBSTITUTED OBHS DERIVATIVE
Descriptor:Estrogen receptor, Nuclear receptor-interacting peptide, 2-methylphenyl (1S,2R,4S)-5,6-bis(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hept-5-ene-2-sulfonate
Authors:Nwachukwu, J.C., Srinivasan, S., Zheng, Y., Wang, S., Min, J., Dong, C., Liao, Z., Cavett, V., Nowak, J., Houtman, R., Carlson, K.E., Josan, J.S., Elemento, O., Katzenellenbogen, J.A., Zhou, H.B., Nettles, K.W.
Deposit date:2015-05-05
Release date:2016-05-04
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Predictive features of ligand-specific signaling through the estrogen receptor.
Mol.Syst.Biol., 12, 2016
4ZNV
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CRYSTAL STRUCTURE OF THE ER-ALPHA LIGAND-BINDING DOMAIN (Y537S) IN COMPLEX WITH A 2-METHOXY-SUBSTITUTED OBHS DERIVATIVE
Descriptor:Estrogen receptor, Nuclear receptor-interacting peptide, 2-methoxyphenyl (1S,2R,4S)-5,6-bis(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hept-5-ene-2-sulfonate
Authors:Nwachukwu, J.C., Srinivasan, S., Zheng, Y., Wang, S., Min, J., Dong, C., Liao, Z., Cavett, V., Nowak, J., Houtman, R., Carlson, K.E., Josan, J.S., Elemento, O., Katzenellenbogen, J.A., Zhou, H.B., Nettles, K.W.
Deposit date:2015-05-05
Release date:2016-05-04
Method:X-RAY DIFFRACTION (1.771 Å)
Cite:Predictive features of ligand-specific signaling through the estrogen receptor.
Mol.Syst.Biol., 12, 2016
4ZNW
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CRYSTAL STRUCTURE OF THE ER-ALPHA LIGAND-BINDING DOMAIN (Y537S) IN COMPLEX WITH A 4-BROMO-SUBSTITUTED OBHS DERIVATIVE
Descriptor:Estrogen receptor, Nuclear receptor-interacting peptide, 4-bromophenyl (1S,2R,4S)-5,6-bis(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hept-5-ene-2-sulfonate
Authors:Nwachukwu, J.C., Srinivasan, S., Zheng, Y., Wang, S., Min, J., Dong, C., Liao, Z., Cavett, V., Nowak, J., Houtman, R., Carlson, K.E., Josan, J.S., Elemento, O., Katzenellenbogen, J.A., Zhou, H.B., Nettles, K.W.
Deposit date:2015-05-05
Release date:2016-05-04
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:Predictive features of ligand-specific signaling through the estrogen receptor.
Mol.Syst.Biol., 12, 2016
5DI7
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CRYSTAL STRUCTURE OF THE ER-ALPHA LIGAND-BINDING DOMAIN IN COMPLEX WITH AN METHYL-SUBSTITUTED A-CD RING ESTROGEN DERIVATIVE (1S,3AR,5S,7AS)-5-(4-HYDROXY-2-METHYLPHENYL)-7A-METHYLOCTAHYDRO-1H-INDEN-1-OL
Descriptor:Estrogen receptor, Nuclear receptor coactivator 2, (1S,3aR,5S,7aS)-5-(4-hydroxy-2-methylphenyl)-7a-methyloctahydro-1H-inden-1-ol
Authors:Nwachukwu, J.C., Srinivasan, S., Zheng, Y., Wang, S., Min, J., Dong, C., Liao, Z., Cavett, V., Nowak, J., Houtman, R., Carlson, K.E., Josan, J.S., Elemento, O., Katzenellenbogen, J.A., Zhou, H.B., Nettles, K.W.
Deposit date:2015-08-31
Release date:2016-05-04
Method:X-RAY DIFFRACTION (2.241 Å)
Cite:Predictive features of ligand-specific signaling through the estrogen receptor.
Mol.Syst.Biol., 12, 2016
5DID
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CRYSTAL STRUCTURE OF THE ER-ALPHA LIGAND-BINDING DOMAIN IN COMPLEX WITH A DIFLUORO-SUBSTITUTED A-CD RING ESTROGEN DERIVATIVE (1S,3AR,5S,7AS)-5-(2,3-DIFLUORO-4-HYDROXYPHENYL)-7A-METHYLOCTAHYDRO-1H-INDEN-1-OL
Descriptor:Estrogen receptor, Nuclear receptor coactivator 2, (1S,3aR,5S,7aS)-5-(2,3-difluoro-4-hydroxyphenyl)-7a-methyloctahydro-1H-inden-1-ol
Authors:Nwachukwu, J.C., Srinivasan, S., Zheng, Y., Wang, S., Min, J., Dong, C., Liao, Z., Cavett, V., Nowak, J., Houtman, R., Carlson, K.E., Josan, J.S., Elemento, O., Katzenellenbogen, J.A., Zhou, H.B., Nettles, K.W.
Deposit date:2015-08-31
Release date:2016-05-04
Method:X-RAY DIFFRACTION (2.24 Å)
Cite:Predictive features of ligand-specific signaling through the estrogen receptor.
Mol.Syst.Biol., 12, 2016
5DIE
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CRYSTAL STRUCTURE OF THE ER-ALPHA LIGAND-BINDING DOMAIN IN COMPLEX WITH A TRIFLUORO-SUBSTITUTED A-CD RING ESTROGEN DERIVATIVE (1S,3AR,5S,7AS)-7A-METHYL-5-(2,3,5-TRIFLUORO-4-HYDROXYPHENYL)OCTAHYDRO-1H-INDEN-1-OL
Descriptor:Estrogen receptor, Nuclear receptor coactivator 2, (1S,3aR,5S,7aS)-7a-methyl-5-(2,3,5-trifluoro-4-hydroxyphenyl)octahydro-1H-inden-1-ol
Authors:Nwachukwu, J.C., Srinivasan, S., Zheng, Y., Wang, S., Min, J., Dong, C., Liao, Z., Cavett, V., Nowak, J., Houtman, R., Carlson, K.E., Josan, J.S., Elemento, O., Katzenellenbogen, J.A., Zhou, H.B., Nettles, K.W.
Deposit date:2015-08-31
Release date:2016-05-04
Method:X-RAY DIFFRACTION (2.24 Å)
Cite:Predictive features of ligand-specific signaling through the estrogen receptor.
Mol.Syst.Biol., 12, 2016
5DIG
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CRYSTAL STRUCTURE OF THE ER-ALPHA LIGAND-BINDING DOMAIN IN COMPLEX WITH A TRIFLUOROMETHYL-SUBSTITUTED A-CD RING ESTROGEN DERIVATIVE (1S,3AR,5S,7AS)-5-[4-HYDROXY-2-(TRIFLUOROMETHYL)PHENYL]-7A-METHYLOCTAHYDRO-1H-INDEN-1-OL
Descriptor:Estrogen receptor, Nuclear receptor coactivator 2, (1S,3aR,5S,7aS)-5-[4-hydroxy-2-(trifluoromethyl)phenyl]-7a-methyloctahydro-1H-inden-1-ol
Authors:Nwachukwu, J.C., Srinivasan, S., Zheng, Y., Wang, S., Min, J., Dong, C., Liao, Z., Cavett, V., Nowak, J., Houtman, R., Carlson, K.E., Josan, J.S., Elemento, O., Katzenellenbogen, J.A., Zhou, H.B., Nettles, K.W.
Deposit date:2015-09-01
Release date:2016-05-04
Method:X-RAY DIFFRACTION (2.24 Å)
Cite:Predictive features of ligand-specific signaling through the estrogen receptor.
Mol.Syst.Biol., 12, 2016
5DK9
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CRYSTAL STRUCTURE OF THE ER-ALPHA LIGAND-BINDING DOMAIN IN COMPLEX WITH A PHENYLAMINO-SUBSTITUTED ETHYL TRIARYL-ETHYLENE DERIVATIVE 4,4'-{2-[3-(PHENYLAMINO)PHENYL]BUT-1-ENE-1,1-DIYL}DIPHENOL
Descriptor:Estrogen receptor, Nuclear receptor coactivator 2, 4,4'-{2-[3-(phenylamino)phenyl]but-1-ene-1,1-diyl}diphenol
Authors:Nwachukwu, J.C., Srinivasan, S., Zheng, Y., Wang, S., Min, J., Dong, C., Liao, Z., Cavett, V., Nowak, J., Houtman, R., Carlson, K.E., Josan, J.S., Elemento, O., Katzenellenbogen, J.A., Zhou, H.B., Nettles, K.W.
Deposit date:2015-09-03
Release date:2016-05-04
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Predictive features of ligand-specific signaling through the estrogen receptor.
Mol.Syst.Biol., 12, 2016
5DKB
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CRYSTAL STRUCTURE OF THE ER-ALPHA LIGAND-BINDING DOMAIN IN COMPLEX WITH A 3-METHYLPHENYLAMINO-SUBSTITUTED ETHYL TRIARYL-ETHYLENE DERIVATIVE 4,4'-(2-{3-[(3-METHYLPHENYL)AMINO]PHENYL}BUT-1-ENE-1,1-DIYL)DIPHENOL
Descriptor:Estrogen receptor, Nuclear receptor coactivator 2, 4,4'-(2-{3-[(3-methylphenyl)amino]phenyl}but-1-ene-1,1-diyl)diphenol
Authors:Nwachukwu, J.C., Srinivasan, S., Zheng, Y., Wang, S., Min, J., Dong, C., Liao, Z., Cavett, V., Nowak, J., Houtman, R., Carlson, K.E., Josan, J.S., Elemento, O., Katzenellenbogen, J.A., Zhou, H.B., Nettles, K.W.
Deposit date:2015-09-03
Release date:2016-05-04
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Predictive features of ligand-specific signaling through the estrogen receptor.
Mol.Syst.Biol., 12, 2016
5DKE
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CRYSTAL STRUCTURE OF THE ER-ALPHA LIGAND-BINDING DOMAIN IN COMPLEX WITH A 3-NAPHTHYL-SUBSTITUTED, METHYL, CIS-DIARYL-ETHYLENE COMPOUND 4,4'-[2-(NAPHTHALEN-2-YL)PROP-1-ENE-1,1-DIYL]DIPHENOL
Descriptor:Estrogen receptor, Nuclear receptor coactivator 2, 4,4'-[2-(naphthalen-2-yl)prop-1-ene-1,1-diyl]diphenol
Authors:Nwachukwu, J.C., Srinivasan, S., Zheng, Y., Wang, S., Min, J., Dong, C., Liao, Z., Cavett, V., Nowak, J., Houtman, R., Carlson, K.E., Josan, J.S., Elemento, O., Katzenellenbogen, J.A., Zhou, H.B., Nettles, K.W.
Deposit date:2015-09-03
Release date:2016-05-04
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Predictive features of ligand-specific signaling through the estrogen receptor.
Mol.Syst.Biol., 12, 2016
5DKG
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CRYSTAL STRUCTURE OF THE ER-ALPHA LIGAND-BINDING DOMAIN IN COMPLEX WITH A T-BUTYL-SUBSTITUTED, METHYL, TRIARYL-ETHYLENE DERIVATIVE 4,4'-[2-(4-TERT-BUTYLPHENYL)PROP-1-ENE-1,1-DIYL]DIPHENOL
Descriptor:Estrogen receptor, Nuclear receptor coactivator 2, 4,4'-[2-(4-tert-butylphenyl)prop-1-ene-1,1-diyl]diphenol
Authors:Nwachukwu, J.C., Srinivasan, S., Zheng, Y., Wang, S., Min, J., Dong, C., Liao, Z., Cavett, V., Nowak, J., Houtman, R., Carlson, K.E., Josan, J.S., Elemento, O., Katzenellenbogen, J.A., Zhou, H.B., Nettles, K.W.
Deposit date:2015-09-03
Release date:2016-05-04
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Predictive features of ligand-specific signaling through the estrogen receptor.
Mol.Syst.Biol., 12, 2016
5DKS
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CRYSTAL STRUCTURE OF THE ER-ALPHA LIGAND-BINDING DOMAIN IN COMPLEX WITH A 2-NAPHTHYLAMINO-SUBSTITUTED, ETHYL, TRIARYL-ETHYLENE DERIVATIVE 4,4'-{2-[3-(NAPHTHALEN-1-YLAMINO)PHENYL]BUT-1-ENE-1,1-DIYL}DIPHENOL
Descriptor:Estrogen receptor, Nuclear receptor coactivator 2, 4,4'-{2-[3-(naphthalen-1-ylamino)phenyl]but-1-ene-1,1-diyl}diphenol
Authors:Nwachukwu, J.C., Srinivasan, S., Zheng, Y., Wang, S., Min, J., Dong, C., Liao, Z., Cavett, V., Nowak, J., Houtman, R., Carlson, K.E., Josan, J.S., Elemento, O., Katzenellenbogen, J.A., Zhou, H.B., Nettles, K.W.
Deposit date:2015-09-03
Release date:2016-05-04
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Predictive features of ligand-specific signaling through the estrogen receptor.
Mol.Syst.Biol., 12, 2016
5DL4
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CRYSTAL STRUCTURE OF THE ER-ALPHA LIGAND-BINDING DOMAIN IN COMPLEX WITH A PHENYLAMINO-SUBSTITUTED, METHYL, TRIARYL-ETHYLENE DERIVATIVE 4,4'-{2-[3-(PHENYLAMINO)PHENYL]PROP-1-ENE-1,1-DIYL}DIPHENOL
Descriptor:Estrogen receptor, Nuclear receptor coactivator 2, 4,4'-{2-[3-(phenylamino)phenyl]prop-1-ene-1,1-diyl}diphenol
Authors:Nwachukwu, J.C., Srinivasan, S., Zheng, Y., Wang, S., Min, J., Dong, C., Liao, Z., Cavett, V., Nowak, J., Houtman, R., Carlson, K.E., Josan, J.S., Elemento, O., Katzenellenbogen, J.A., Zhou, H.B., Nettles, K.W.
Deposit date:2015-09-04
Release date:2016-05-04
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Predictive features of ligand-specific signaling through the estrogen receptor.
Mol.Syst.Biol., 12, 2016
5DLR
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CRYSTAL STRUCTURE OF THE ER-ALPHA LIGAND-BINDING DOMAIN IN COMPLEX WITH A TRIARYL-ETHYLENE COMPOUND 4,4'-(2-PHENYLETHENE-1,1-DIYL)DIPHENOL
Descriptor:Estrogen receptor, Nuclear receptor coactivator 2, 4,4'-(2-phenylethene-1,1-diyl)diphenol
Authors:Nwachukwu, J.C., Srinivasan, S., Zheng, Y., Wang, S., Min, J., Dong, C., Liao, Z., Cavett, V., Nowak, J., Houtman, R., Carlson, K.E., Josan, J.S., Elemento, O., Katzenellenbogen, J.A., Zhou, H.B., Nettles, K.W.
Deposit date:2015-09-07
Release date:2016-05-04
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:Predictive features of ligand-specific signaling through the estrogen receptor.
Mol.Syst.Biol., 12, 2016
5DMC
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CRYSTAL STRUCTURE OF THE ER-ALPHA LIGAND-BINDING DOMAIN IN COMPLEX WITH A NITRILE-SUBSTITUTED TRIARYL-ETHYLENE DERIVATIVE 3,3-BIS(4-HYDROXYPHENYL)-2-PHENYLPROP-2-ENENITRILE
Descriptor:Estrogen receptor, Nuclear receptor coactivator 2, 3,3-bis(4-hydroxyphenyl)-2-phenylprop-2-enenitrile
Authors:Nwachukwu, J.C., Srinivasan, S., Zheng, Y., Wang, S., Min, J., Dong, C., Liao, Z., Cavett, V., Nowak, J., Houtman, R., Carlson, K.E., Josan, J.S., Elemento, O., Katzenellenbogen, J.A., Zhou, H.B., Nettles, K.W.
Deposit date:2015-09-08
Release date:2016-05-04
Method:X-RAY DIFFRACTION (2.403 Å)
Cite:Predictive features of ligand-specific signaling through the estrogen receptor.
Mol.Syst.Biol., 12, 2016
5DMF
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CRYSTAL STRUCTURE OF THE ER-ALPHA LIGAND-BINDING DOMAIN IN COMPLEX WITH A 4-FLUOROPHENYLAMINO-SUBSTITUTED, METHYL TRIARYL-ETHYLENE DERIVATIVE 4,4'-(2-{3-[(4-FLUOROPHENYL)AMINO]PHENYL}PROP-1-ENE-1,1-DIYL)DIPHENOL
Descriptor:Estrogen receptor, Nuclear receptor coactivator 2, 4,4'-(2-{3-[(4-fluorophenyl)amino]phenyl}prop-1-ene-1,1-diyl)diphenol
Authors:Nwachukwu, J.C., Srinivasan, S., Zheng, Y., Wang, S., Min, J., Dong, C., Liao, Z., Cavett, V., Nowak, J., Houtman, R., Carlson, K.E., Josan, J.S., Elemento, O., Katzenellenbogen, J.A., Zhou, H.B., Nettles, K.W.
Deposit date:2015-09-08
Release date:2016-05-04
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Predictive features of ligand-specific signaling through the estrogen receptor.
Mol.Syst.Biol., 12, 2016
5DP0
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CRYSTAL STRUCTURE OF THE ER-ALPHA LIGAND-BINDING DOMAIN IN COMPLEX WITH A 4-FLUOROPHENYLAMINO-SUBSTITUTED TRIARYL-ETHYLENE DERIVATIVE 4,4'-(2-{3-[(4-FLUOROPHENYL)AMINO]PHENYL}ETHENE-1,1-DIYL)DIPHENOL
Descriptor:Estrogen receptor, Nuclear receptor coactivator 2, 4,4'-(2-{3-[(4-fluorophenyl)amino]phenyl}ethene-1,1-diyl)diphenol
Authors:Nwachukwu, J.C., Srinivasan, S., Zheng, Y., Wang, S., Min, J., Dong, C., Liao, Z., Cavett, V., Nowak, J., Houtman, R., Carlson, K.E., Josan, J.S., Elemento, O., Katzenellenbogen, J.A., Zhou, H.B., Nettles, K.W.
Deposit date:2015-09-11
Release date:2016-05-04
Method:X-RAY DIFFRACTION (2.382 Å)
Cite:Predictive features of ligand-specific signaling through the estrogen receptor.
Mol.Syst.Biol., 12, 2016
5DRJ
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CRYSTAL STRUCTURE OF THE ER-ALPHA LIGAND-BINDING DOMAIN IN COMPLEX WITH A DICHLORO-SUBSTITUTED, 3-METHYL 2,5-DIARYLTHIOPHENE-CORE LIGAND 4,4'-(3-METHYLTHIENE-2,5-DIYL)BIS(3-CHLOROPHENOL)
Descriptor:Estrogen receptor, Nuclear receptor coactivator 2, 4,4'-(3-methylthiene-2,5-diyl)bis(3-chlorophenol)
Authors:Nwachukwu, J.C., Srinivasan, S., Zheng, Y., Wang, S., Min, J., Dong, C., Liao, Z., Cavett, V., Nowak, J., Houtman, R., Carlson, K.E., Josan, J.S., Elemento, O., Katzenellenbogen, J.A., Zhou, H.B., Nettles, K.W.
Deposit date:2015-09-15
Release date:2016-05-04
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:Predictive features of ligand-specific signaling through the estrogen receptor.
Mol.Syst.Biol., 12, 2016