5YFM | |
5YFN | | HUMAN ISOCITRATE DEHYDROGENASE 1 BOUND WITH ISOCITRATE | | Descriptor: | Isocitrate dehydrogenase [NADP] cytoplasmic, MAGNESIUM ION, ISOCITRIC ACID, ... | | Authors: | Nordlund, P., Chen, D., Jansson, A., Larsson, A. | | Deposit date: | 2017-09-21 | | Release date: | 2017-10-25 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Human isocitrate dehydrogenase 1 bound with isocitrate
To Be Published
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2VKQ | | CRYSTAL STRUCTURE OF HUMAN CYTOSOLIC 5'-NUCLEOTIDASE III (CN-III, NT5C3) IN COMPLEX WITH BERYLLIUM TRIFLUORIDE | | Descriptor: | CYTOSOLIC 5'-NUCLEOTIDASE III, BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION | | Authors: | Wallden, K., Moche, M., Arrowsmith, C.H., Berglund, H., Busam, R., Collins, R., Dahlgren, L.G., Edwards, A., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Herman, M.D., Johansson, A., Johansson, I., Kallas, A., Karlberg, T., Kotenyova, T., Lehtio, L., Nilsson, M.E., Nyman, T., Persson, C., Sagemark, J., Thorsell, A.G., Tresaugues, L., van den Berg, S., Weigelt, J., Welin, M., Nordlund, P., Structural Genomics Consortium (SGC) | | Deposit date: | 2007-12-21 | | Release date: | 2008-01-08 | | Last modified: | 2015-04-22 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Crystal Structure of Human Cytosolic 5'- Nucleotidase III
To be Published
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1BIQ | | RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 BETA CHAIN MUTANT E238A | | Descriptor: | PROTEIN R2 OF RIBONUCLEOTIDE REDUCTASE, FE (II) ION, FE (III) ION, ... | | Authors: | Logan, D.T., Demare, F., Persson, B.O., Slaby, A., Sjoberg, B.M., Nordlund, P. | | Deposit date: | 1998-06-18 | | Release date: | 1999-01-13 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | Crystal structures of two self-hydroxylating ribonucleotide reductase protein R2 mutants: structural basis for the oxygen-insertion step of hydroxylation reactions catalyzed by diiron proteins.
Biochemistry, 37, 1998
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1MRR | |
1MTY | | METHANE MONOOXYGENASE HYDROXYLASE FROM METHYLOCOCCUS CAPSULATUS (BATH) | | Descriptor: | METHANE MONOOXYGENASE HYDROXYLASE, FE (III) ION | | Authors: | Rosenzweig, A.C., Nordlund, P., Lippard, S.J., Frederick, C.A. | | Deposit date: | 1996-07-10 | | Release date: | 1997-04-21 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Crystal structures of the methane monooxygenase hydroxylase from Methylococcus capsulatus (Bath): implications for substrate gating and component interactions.
Proteins, 29, 1997
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1PFR | | RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 BETA CHAIN | | Descriptor: | PROTEIN R2 OF RIBONUCLEOTIDE REDUCTASE, FE (III) ION, MERCURY (II) ION | | Authors: | Logan, D.T., Su, X.D., Aberg, A., Regnstrom, K., Hajdu, J., Eklund, H., Nordlund, P. | | Deposit date: | 1996-12-03 | | Release date: | 1997-03-12 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Crystal structure of reduced protein R2 of ribonucleotide reductase: the structural basis for oxygen activation at a dinuclear iron site.
Structure, 4, 1996
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1PHR | | THE CRYSTAL STRUCTURE OF A LOW MOLECULAR PHOSPHOTYROSINE PROTEIN PHOSPHATASE | | Descriptor: | LOW MOLECULAR WEIGHT PHOSPHOTYROSINE PROTEIN PHOSPHATASE, SULFATE ION | | Authors: | Su, X.-D., Taddei, N., Stefani, M., Ramponi, G., Nordlund, P. | | Deposit date: | 1994-07-05 | | Release date: | 1995-07-31 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | The crystal structure of a low-molecular-weight phosphotyrosine protein phosphatase.
Nature, 370, 1994
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1XIK | | RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 BETA CHAIN | | Descriptor: | PROTEIN R2 OF RIBONUCLEOTIDE REDUCTASE, FE (II) ION, MERCURY (II) ION | | Authors: | Logan, D.T., Su, X.-D., Aberg, A., Regnstrom, K., Hajdu, J., Eklund, H., Nordlund, P. | | Deposit date: | 1996-08-06 | | Release date: | 1997-03-12 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Crystal structure of reduced protein R2 of ribonucleotide reductase: the structural basis for oxygen activation at a dinuclear iron site.
Structure, 4, 1996
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2BW0 | | CRYSTAL STRUCTURE OF THE HYDROLASE DOMAIN OF HUMAN 10-FORMYLTETRAHYDROFOLATE 2 DEHYDROGENASE | | Descriptor: | 10-FORMYLTETRAHYDROFOLATE DEHYDROGENASE, SULFATE ION | | Authors: | Ogg, D.J., Stenmark, P., Arrowsmith, C., Edwards, A., Ehn, M., Graslund, S., Hammarstrom, M., Hallberg, M., Kotenyova, T., Nilsson-Ehle, P., Nordlund, P., Persson, C., Sagemark, J., Schuler, H., Sundstrom, M., Thorsell, A., Dobritzsch, D., Weigelt, J. | | Deposit date: | 2005-07-07 | | Release date: | 2005-07-08 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Structures of the Hydrolase Domain of Human 10-Formyltetrahydrofolate Dehydrogenase and its Complex with a Substrate Analogue.
Acta Crystallogr.,Sect.D, 62, 2006
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2BZN | | CRYSTAL STRUCTURE OF HUMAN GUANOSINE MONOPHOSPHATE REDUCTASE 2 GMPR2 IN COMPLEX WITH IMP | | Descriptor: | GMP REDUCTASE 2, INOSINIC ACID | | Authors: | Stenmark, P., Kursula, P., Arrowsmith, C., Berglund, H., Edwards, A., Ehn, M., Graslund, S., Hammarstrom, M., Hallberg, B.M., Kotenyova, T., Nilsson-Ehle, P., Nordlund, P., Ogg, D., Persson, C., Sagemark, J., Schuler, H., Sundstrom, M., Thorsell, A., Weigelt, J. | | Deposit date: | 2005-08-19 | | Release date: | 2005-09-02 | | Last modified: | 2011-11-30 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | Cofactor Mobility Determines Reaction Outcome in the Impdh and Gmpr (Beta-Alpha)(8) Barrel Enzymes.
Nat.Chem.Biol., 7, 2011
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2C4K | | CRYSTAL STRUCTURE OF HUMAN PHOSPHORIBOSYLPYROPHOSPHATE SYNTHETASE- ASSOCIATED PROTEIN 39 (PAP39) | | Descriptor: | PHOSPHORIBOSYL PYROPHOSPHATE SYNTHETASE-ASSOCIATED PROTEIN 1, SULFATE ION, TRIS(HYDROXYETHYL)AMINOMETHANE | | Authors: | Kursula, P., Stenmark, P., Arrowsmith, C., Berglund, H., Edwards, A., Ehn, M., Flodin, S., Graslund, S., Hammarstrom, M., Hallberg, B.M., Holmberg Schiavone, L., Kotenyova, T., Nilsson-Ehle, P., Ogg, D., Persson, C., Sagemark, J., Schuler, H., Sundstrom, M., Thorsell, A.G., Van Den Berg, S., Weigelt, J., Nordlund, P. | | Deposit date: | 2005-10-20 | | Release date: | 2005-10-24 | | Last modified: | 2018-01-17 | | Method: | X-RAY DIFFRACTION (2.65 Å) | | Cite: | Crystal Structure of Human Phosphoribosylpyrophosphate Synthetase-Associated Protein 39 (Pap39)
To be Published
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2C6Q | | CRYSTAL STRUCTURE OF HUMAN GUANOSINE MONOPHOSPHATE REDUCTASE 2 GMPR2 IN COMPLEX WITH IMP AND NADPH | | Descriptor: | GMP REDUCTASE 2, INOSINIC ACID, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | Authors: | Kursula, P., Stenmark, P., Arrowsmith, C., Berglund, H., Edwards, A., Ehn, M., Graslund, S., Hammarstrom, M., Hallberg, B.M., Kotenyova, T., Nilsson-Ehle, P., Ogg, D., Persson, C., Sagemark, J., Schuler, H., Sundstrom, M., Thorsell, A., Weigelt, J., Nordlund, P. | | Deposit date: | 2005-11-11 | | Release date: | 2005-11-30 | | Last modified: | 2011-11-30 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Cofactor Mobility Determines Reaction Outcome in the Impdh and Gmpr (Beta-Alpha)(8) Barrel Enzymes.
Nat.Chem.Biol., 7, 2011
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2CAR | | CRYSTAL STRUCTURE OF HUMAN INOSINE TRIPHOSPHATASE | | Descriptor: | INOSINE TRIPHOSPHATE PYROPHOSPHATASE | | Authors: | Stenmark, P., Kursula, P., Arrowsmith, C., Berglund, H., Edwards, A., Ehn, M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Hallberg, B.M., Hogbom, M., Holmberg Schiavone, L., Kotenyova, T., Nilsson-Ehle, P., Nyman, T., Ogg, D., Persson, C., Sagemark, J., Schuler, H., Sundstrom, M., Thorsell, A.G., van den Berg, S., Weigelt, J., Nordlund, P. | | Deposit date: | 2005-12-22 | | Release date: | 2006-01-04 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.09 Å) | | Cite: | Crystal Structure of Human Inosine Triphosphatase. Substrate Binding and Implication of the Inosine Triphosphatase Deficiency Mutation P32T.
J.Biol.Chem., 282, 2007
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2CFI | | THE HYDROLASE DOMAIN OF HUMAN 10-FTHFD IN COMPLEX WITH 6- FORMYLTETRAHYDROPTERIN | | Descriptor: | 10-FORMYLTETRAHYDROFOLATE DEHYDROGENASE, SULFATE ION, 6-FORMYLTETRAHYDROPTERIN | | Authors: | Kursula, P., Stenmark, P., Arrowsmith, C., Edwards, A., Ehn, M., Graslund, S., Hammarstrom, M., Hallberg, M., Kotenyova, T., Nilsson-Ehle, P., Nordlund, P., Ogg, D.J., Persson, C., Sagemark, J., Schuler, H., Sundstrom, M., Thorsell, A., Weigelt, J. | | Deposit date: | 2006-02-21 | | Release date: | 2006-03-14 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Structures of the Hydrolase Domain of Human 10-Formyltetrahydrofolate Dehydrogenase and its Complex with a Substrate Analogue.
Acta Crystallogr.,Sect.D, 62, 2006
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2F73 | | CRYSTAL STRUCTURE OF HUMAN FATTY ACID BINDING PROTEIN 1 (FABP1) | | Descriptor: | Fatty acid-binding protein, liver | | Authors: | Kursula, P., Thorsell, A.G., Arrowsmith, C., Berglund, H., Edwards, A., Ehn, M., Flodin, S., Graslund, S., Hammarstrom, M., Holmberg Schiavone, L., Kotenyova, T., Nilsson-Ehle, P., Nordlund, P., Nyman, T., Ogg, D., Persson, C., Sagemark, J., Stenmark, P., Sundstrom, M., van den Berg, S., Weigelt, J., Hallberg, B.M., Structural Genomics Consortium (SGC) | | Deposit date: | 2005-11-30 | | Release date: | 2005-12-13 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Crystal structure of human FABP1
To be Published
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2FIM | | STRUCTURE OF THE C-TERMINAL DOMAIN OF HUMAN TUBBY-LIKE PROTEIN 1 | | Descriptor: | Tubby related protein 1, 3-(N,N-DIMETHYLOCTYLAMMONIO)PROPANESULFONATE, SULFATE ION | | Authors: | Hallberg, B.M., Ogg, D., Arrowsmith, C., Berglund, H., Edwards, A., Ehn, M., Flodin, S., Graslund, S., Hammarstrom, M., Hogbom, M., Holmberg-Schiavone, L., Kotenyova, T., Kursula, P., Nilsson-Ehle, P., Nordlund, P., Nyman, T., Sagemark, J., Stenmark, P., Sundstrom, M., Thorsell, A.G., Van Den Berg, S., Weigelt, J., Persson, C. | | Deposit date: | 2005-12-29 | | Release date: | 2006-02-07 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structure of the C-terminal domain of Human Tubby-like protein 1
To be published
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2FVZ | | HUMAN INOSITOL MONOPHOSPHOSPHATASE 2 | | Descriptor: | Inositol monophosphatase 2 | | Authors: | Ogg, D., Hallberg, B.M., Arrowsmith, C., Berglund, H., Collins, R., Edwards, A., Ehn, M., Flodin, S., Graslund, S., Hammarstrom, M., Hogbom, M., Holmberg-Schiavone, L., Kotenyova, T., Kursula, P., Nilsson-Ehle, P., Nordlund, P., Nyman, T., Persson, C., Sagemark, J., Stenmark, P., Sundstrom, M., Van Den Berg, S., Weigelt, J., Thorsell, A.G., Structural Genomics Consortium (SGC) | | Deposit date: | 2006-01-31 | | Release date: | 2006-02-21 | | Last modified: | 2018-05-23 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structure of Human Inositol Monophosphatase 2
To be published
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2GSE | | CRYSTAL STRUCTURE OF HUMAN DIHYDROPYRIMIDINEASE-LIKE 2 | | Descriptor: | Dihydropyrimidinase-related protein 2, CALCIUM ION | | Authors: | Ogg, D., Stenmark, P., Arrowsmith, C., Berglund, H., Collins, R., Edwards, A., Ehn, M., Flodin, S., Flores, A., Graslund, S., Hallberg, B.M., Hammarstrom, M., Kotenyova, T., Kursula, P., Nilsson-Ehle, P., Nyman, T., Persson, C., Sagemark, J., Sundstrom, M., Holmberg-Schiavone, L., Thorsell, A.G., Uppenberg, J., Van Den Berg, S., Weigelt, J., Nordlund, P., Structural Genomics Consortium (SGC) | | Deposit date: | 2006-04-26 | | Release date: | 2006-05-09 | | Last modified: | 2018-01-24 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | The structure of human collapsin response mediator protein 2, a regulator of axonal growth.
J.Neurochem., 101, 2007
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2J2C | | CRYSTAL STRUCTURE OF HUMAN CYTOSOLIC 5'-NUCLEOTIDASE II (NT5C2, CN-II) | | Descriptor: | CYTOSOLIC PURINE 5'-NUCLEOTIDASE, GLYCEROL, SULFATE ION, ... | | Authors: | Wallden, K., Stenmark, P., Arrowsmith, C., Berglund, H., Busam, R., Collins, R., Edwards, A., Ehn, M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Hallberg, B.M., Holmberg Schiavone, L., Hogbom, M., Karlberg, T., Kotenyova, T., Loppnau, P., Magnusdottir, A., Nilsson-Ehle, P., Nyman, T., Ogg, D., Persson, C., Sagemark, J., Sundstrom, M., Uppenberg, J., Thorsell, A.G., Van Den Berg, S., Weigelt, J., Welin, M., Nordlund, P. | | Deposit date: | 2006-08-16 | | Release date: | 2006-09-19 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Crystal Structure of Human Cytosolic 5'- Nucleotidase II: Insights Into Allosteric Regulation and Substrate Recognition
J.Biol.Chem., 282, 2007
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2J4E | | THE ITP COMPLEX OF HUMAN INOSINE TRIPHOSPHATASE | | Descriptor: | INOSINE TRIPHOSPHATE PYROPHOSPHATASE, INOSINE 5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | Authors: | Stenmark, P., Kursula, P., Arrowsmith, C., Berglund, H., Busam, R., Collins, R., Edwards, A., Ehn, M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Hallberg, B.M., Holmbergschiavone, L., Hogbom, M., Kotenyova, T., Landry, R., Loppnau, P., Magnusdottir, A., Nilsson-Ehle, P., Nyman, T., Ogg, D., Persson, C., Sagemark, J., Sundstrom, M., Uppenberg, J., Thorsell, A.G., Schuler, H., Van Den Berg, S., Wallden, K., Weigelt, J., Nordlund, P. | | Deposit date: | 2006-08-29 | | Release date: | 2006-09-20 | | Last modified: | 2013-11-20 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Crystal Structure of Human Inosine Triphosphatase: Substrate Binding and Implication of the Inosine Triphosphatase Deficiency Mutation P32T.
J.Biol.Chem., 282, 2007
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2JC9 | | CRYSTAL STRUCTURE OF HUMAN CYTOSOLIC 5'-NUCLEOTIDASE II IN COMPLEX WITH ADENOSINE | | Descriptor: | CYTOSOLIC PURINE 5'-NUCLEOTIDASE, GLYCEROL, MAGNESIUM ION, ... | | Authors: | Wallden, K., Stenmark, P., Arrowsmith, C., Berglund, H., Busam, R., Collins, R., Edwards, A., Ehn, M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Hallberg, B.M., Holmberg, S.L., Hogbom, M., Karlberg, T., Kotenyova, T., Magnusdottir, A., Nilsson-Ehle, P., Nyman, T., Ogg, D., Persson, C., Sagemark, J., Sundstrom, M., Uppenberg, J., Thorsell, A.G., Van Den Berg, S., Loppnau, P., Weigelt, J., Welin, M., Nordlund, P. | | Deposit date: | 2006-12-21 | | Release date: | 2007-01-02 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Crystal Structure of Human Cytosolic 5'-Nucleotidase II: Insights Into Allosteric Regulation and Substrate Recognition
J.Biol.Chem., 282, 2007
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2JCM | | CRYSTAL STRUCTURE OF HUMAN CYTOSOLIC 5'-NUCLEOTIDASE II IN COMPLEX WITH BERYLLIUM TRIFLUORIDE | | Descriptor: | CYTOSOLIC PURINE 5'-NUCLEOTIDASE, UNKNOWN ATOM OR ION, MAGNESIUM ION, ... | | Authors: | Wallden, K., Stenmark, P., Arrowsmith, C., Berglund, H., Busam, R., Collins, R., Edwards, A., Ehn, M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Hallberg, B.M., Holmberg Schiavone, L., Hogbom, M., Karlberg, T., Kotenyova, T., Magnusdottir, A., Nilsson-Ehle, P., Nyman, T., Ogg, D., Persson, C., Sagemark, J., Sundstrom, M., Uppenberg, J., Thorsell, A.G., Van Den Berg, S., Loppnau, P., Weigelt, J., Welin, M., Nordlund, P. | | Deposit date: | 2006-12-27 | | Release date: | 2007-01-30 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | Crystal Structure of Human Cytosolic 5'- Nucleotidase II: Insights Into Allosteric Regulation and Substrate Recognition
J.Biol.Chem., 282, 2007
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2VO1 | | CRYSTAL STRUCTURE OF THE SYNTHETASE DOMAIN OF HUMAN CTP SYNTHETASE | | Descriptor: | CTP SYNTHASE 1, SULFATE ION | | Authors: | Stenmark, P., Kursula, P., Arrowsmith, C., Berglund, H., Edwards, A., Ehn, M., Flodin, S., Graslund, S., Hammarstrom, M., Hallberg, B.M., Holmberg-Schiavone, L., Kotenyoa, T., Moche, M., Nilsson-Ehle, P., Ogg, D., Persson, C., Sagemark, J., Schuler, H., Sundstrom, M., Thorsell, A.G., Van Den Berg, S., Weigelt, J., Nordlund, P. | | Deposit date: | 2008-02-08 | | Release date: | 2008-03-11 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structure of the Synthetase Domain of Human Ctp Synthetase, a Target for Anticancer Therapy.
Acta Crystallogr.,Sect.F, 62, 2006
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2XJD | |
