Author results

1TND
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THE 2.2 ANGSTROMS CRYSTAL STRUCTURE OF TRANSDUCIN-ALPHA COMPLEXED WITH GTP GAMMA S
Descriptor:TRANSDUCIN, MAGNESIUM ION, CACODYLATE ION, ...
Authors:Noel, J.P., Hamm, H.E., Sigler, P.B.
Deposit date:1994-03-31
Release date:1994-07-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The 2.2 A crystal structure of transducin-alpha complexed with GTP gamma S.
Nature, 366, 1993
3LZ9
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THE CRYSTAL STRUCTURE OF 5-EPI-ARISTOLOCHENE SYNTHASE M4 MUTANT COMPLEXED WITH (2-TRANS,6-TRANS)-2-FLUOROFARNESYL DIPHOSPHATE
Descriptor:Aristolochene synthase, (2Z,6E)-2-fluoro-3,7,11-trimethyldodeca-2,6,10-trien-1-yl trihydrogen diphosphate, MAGNESIUM ION
Authors:Noel, J.P., Dellas, N., Faraldos, J.A., Zhao, M., Hess Jr., B.A., Smentek, L., Coates, R.M., O'Maille, P.E.
Deposit date:2010-03-01
Release date:2010-04-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Structural elucidation of cisoid and transoid cyclization pathways of a sesquiterpene synthase using 2-fluorofarnesyl diphosphates.
Acs Chem.Biol., 5, 2010
3M00
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CRYSTAL STRUCTURE OF 5-EPI-ARISTOLOCHENE SYNTHASE M4 MUTANT COMPLEXED WITH (2-CIS,6-TRANS)-2-FLUOROFARNESYL DIPHOSPHATE
Descriptor:Aristolochene synthase, (2E,6E)-2-fluoro-3,7,11-trimethyldodeca-2,6,10-trien-1-yl trihydrogen diphosphate, MAGNESIUM ION
Authors:Noel, J.P., Dellas, N., Faraldos, J.A., Zhao, M., Hess Jr., B.A., Smentek, L., Coates, R.M., O'Maille, P.E.
Deposit date:2010-03-02
Release date:2010-07-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural elucidation of cisoid and transoid cyclization pathways of a sesquiterpene synthase using 2-fluorofarnesyl diphosphates.
Acs Chem.Biol., 5, 2010
3M01
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THE CRYSTAL STRUCTURE OF 5-EPI-ARISTOLOCHENE SYNTHASE COMPLEXED WITH (2-TRANS,6-TRANS)-2-FLUOROFARNESYL DIPHOSPHATE
Descriptor:Aristolochene synthase, (2Z,6E)-2-fluoro-3,7,11-trimethyldodeca-2,6,10-trien-1-yl trihydrogen diphosphate, MAGNESIUM ION, ...
Authors:Noel, J.P., Dellas, N., Faraldos, J.A., Zhao, M., Hess Jr., B.A., Smentek, L., Coates, R.M., O'Maille, P.E.
Deposit date:2010-03-02
Release date:2010-07-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural elucidation of cisoid and transoid cyclization pathways of a sesquiterpene synthase using 2-fluorofarnesyl diphosphates.
Acs Chem.Biol., 5, 2010
3M02
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THE CRYSTAL STRUCTURE OF 5-EPI-ARISTOLOCHENE SYNTHASE COMPLEXED WITH (2-CIS,6-TRANS)-2-FLUOROFARNESYL DIPHOSPHATE
Descriptor:Aristolochene synthase, MAGNESIUM ION, (2E,6E)-2-fluoro-3,7,11-trimethyldodeca-2,6,10-trien-1-yl trihydrogen diphosphate
Authors:Noel, J.P., Dellas, N., Faraldos, J.A., Zhao, M., Hess Jr., B.A., Smentek, L., Coates, R.M., O'Maille, P.E.
Deposit date:2010-03-02
Release date:2010-07-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural elucidation of cisoid and transoid cyclization pathways of a sesquiterpene synthase using 2-fluorofarnesyl diphosphates.
Acs Chem.Biol., 5, 2010
4DI5
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CO-CRYSTAL STRUCTURE OF WT 5-EPI-ARISTOLOCHENE SYNTHASE FROM NICOTIANA TOBACCUM WITH GERANILINE
Descriptor:5-epi-aristolochene synthase, ACETATE ION, Geraniline, ...
Authors:Noel, J.P., Starks, C., Crenshaw, C.M.
Deposit date:2012-01-30
Release date:2012-02-29
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Co-crystal structure of WT 5-epi-Aristolochene synthase from Nicotiana tobaccum with geraniline
To be Published
1PIN
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PIN1 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FROM HOMO SAPIENS
Descriptor:PEPTIDYL-PROLYL CIS-TRANS ISOMERASE, ALANINE, PROLINE, ...
Authors:Noel, J.P., Ranganathan, R., Hunter, T.
Deposit date:1998-06-21
Release date:1998-10-14
Last modified:2014-02-26
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Structural and functional analysis of the mitotic rotamase Pin1 suggests substrate recognition is phosphorylation dependent.
Cell(Cambridge,Mass.), 89, 1997
2ITK
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HUMAN PIN1 BOUND TO D-PEPTIDE
Descriptor:Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, D-Peptide, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL
Authors:Noel, J.P., Zhang, Y.
Deposit date:2006-10-19
Release date:2007-05-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Structural basis for high-affinity peptide inhibition of human Pin1.
Acs Chem.Biol., 2, 2007
2Q5A
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HUMAN PIN1 BOUND TO L-PEPTIDE
Descriptor:Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, Five residue peptide, 3,6,9,12,15,18-HEXAOXAICOSANE
Authors:Noel, J.P., Zhang, Y.
Deposit date:2007-05-31
Release date:2007-06-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural basis for high-affinity peptide inhibition of human Pin1.
Acs Chem.Biol., 2, 2007
2Q6I
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SALL WITH CLDA AND LMET
Descriptor:Hypothetical protein, 5'-CHLORO-5'-DEOXYADENOSINE, METHIONINE, ...
Authors:Noel, J.P., Pojer, F.
Deposit date:2007-06-05
Release date:2007-12-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Discovery and characterization of a marine bacterial SAM-dependent chlorinase
Nat.Chem.Biol., 4, 2008
2Q6O
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SALL-Y70T WITH SAM AND CL
Descriptor:Hypothetical Protein, CHLORIDE ION, S-ADENOSYLMETHIONINE
Authors:Noel, J.P., Pojer, F.
Deposit date:2007-06-05
Release date:2007-12-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Discovery and characterization of a marine bacterial SAM-dependent chlorinase
Nat.Chem.Biol., 4, 2008
4DOI
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CRYSTAL STRUCTURE OF ARABIDOPSIS THALIANA CHALCONE ISOMERASE AT3G55120 (ATCHI)
Descriptor:Chalcone--flavonone isomerase 1, NITRATE ION
Authors:Noel, J.P., Louie, G.V., Bowman, M.E.
Deposit date:2012-02-09
Release date:2012-05-09
Last modified:2012-06-06
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Evolution of the chalcone-isomerase fold from fatty-acid binding to stereospecific catalysis.
Nature, 485, 2012
4DOK
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CRYSTAL STRUCTURE OF ARABIDOPSIS THALIANA CHALCONE-ISOMERASE LIKE PROTEIN AT5G05270 (ATCHIL)
Descriptor:Similarity to chalcone-flavonone isomerase, CALCIUM ION, ACETATE ION
Authors:Noel, J.P., Louie, G.V., Bowman, M.E.
Deposit date:2012-02-09
Release date:2012-05-09
Last modified:2012-06-06
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Evolution of the chalcone-isomerase fold from fatty-acid binding to stereospecific catalysis.
Nature, 485, 2012
4DOL
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CRYSTAL STRUCTURE OF ARABIDOPSIS THALIANA FATTY-ACID BINDING PROTEIN AT1G53520 (ATFAP3)
Descriptor:At1g53520, PALMITIC ACID
Authors:Noel, J.P., Louie, G.V., Bowman, M.E.
Deposit date:2012-02-09
Release date:2012-05-09
Last modified:2012-06-06
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Evolution of the chalcone-isomerase fold from fatty-acid binding to stereospecific catalysis.
Nature, 485, 2012
4DOO
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CRYSTAL STRUCTURE OF ARABIDOPSIS THALIANA FATTY-ACID BINDING PROTEIN AT3G63170 (ATFAP1)
Descriptor:Chalcone-flavanone isomerase family protein, LAURIC ACID, POTASSIUM ION
Authors:Noel, J.P., Pojer, F., Louie, G.V., Bowman, M.E.
Deposit date:2012-02-09
Release date:2012-05-09
Last modified:2012-06-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Evolution of the chalcone-isomerase fold from fatty-acid binding to stereospecific catalysis.
Nature, 485, 2012
4QJK
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CRYSTAL STRUCTURE OF M. TUBERCULOSIS PHOSPHOPANTETHEINYL TRANSFERASE PPTT
Descriptor:Phosphopantetheinyl transferase PptT, COENZYME A, SULFATE ION
Authors:Noel, J.P., Burkart, M.D., Vickery, C.R.
Deposit date:2014-06-04
Release date:2014-07-16
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.59 Å)
Cite:Structure, biochemistry, and inhibition of essential 4'-phosphopantetheinyl transferases from two species of mycobacteria.
Acs Chem.Biol., 9, 2014
4QJL
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CRYSTAL STRUCTURE OF M. ULCERANS PHOSPHOPANTETHEINYL TRANSFERASE MUPPT
Descriptor:Phosphopantetheinyl transferase, PptII, COENZYME A, ...
Authors:Noel, J.P., Burkart, M.D., Vickery, C.R.
Deposit date:2014-06-04
Release date:2014-07-16
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structure, biochemistry, and inhibition of essential 4'-phosphopantetheinyl transferases from two species of mycobacteria.
Acs Chem.Biol., 9, 2014
4R1S
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CRYSTAL STRUCTURE OF PETUNIA HYDRIDA CINNAMOYL-COA REDUCTASE
Descriptor:cinnamoyl CoA reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Noel, J.P., Louie, G.V., Bowman, M.E., Bomati, E.K.
Deposit date:2014-08-07
Release date:2014-10-01
Last modified:2014-11-12
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural Studies of Cinnamoyl-CoA Reductase and Cinnamyl-Alcohol Dehydrogenase, Key Enzymes of Monolignol Biosynthesis.
Plant Cell, 26, 2014
4R1T
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CRYSTAL STRUCTURE OF PETUNIA HYDRIDA CINNAMOYL-COA REDUCTASE
Descriptor:cinnamoyl CoA reductase, molecular iodine
Authors:Noel, J.P., Louie, G.V., Bowman, M.E., Bomati, E.K.
Deposit date:2014-08-07
Release date:2014-10-01
Last modified:2014-11-12
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural Studies of Cinnamoyl-CoA Reductase and Cinnamyl-Alcohol Dehydrogenase, Key Enzymes of Monolignol Biosynthesis.
Plant Cell, 26, 2014
4R1U
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CRYSTAL STRUCTURE OF MEDICAGO TRUNCATULA CINNAMOYL-COA REDUCTASE
Descriptor:Cinnamoyl CoA reductase, ACETATE ION
Authors:Noel, J.P., Bomati, E.K., Louie, G.V., Bowman, M.E.
Deposit date:2014-08-07
Release date:2014-10-01
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:Structural Studies of Cinnamoyl-CoA Reductase and Cinnamyl-Alcohol Dehydrogenase, Key Enzymes of Monolignol Biosynthesis.
Plant Cell, 26, 2014
5DHI
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NICOTIANA TABACUM 5-EPI-ARISTOLOCHENE SYNTHASE MUTANT W273E - NONALKYLATED
Descriptor:5-epi-aristolochene synthase, MAGNESIUM ION
Authors:Noel, J.P., Kersten, R.D.
Deposit date:2015-08-31
Release date:2015-09-16
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Mechanism-Based Post-Translational Modification and Inactivation in Terpene Synthases.
Acs Chem.Biol., 10, 2015
5DHK
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NICOTIANA TABACUM 5-EPI-ARISTOLOCHENE SYNTHASE MUTANT W273E - ALKYLATED
Descriptor:5-epi-aristolochene synthase, MAGNESIUM ION, FARNESYL
Authors:Noel, J.P., Kersten, R.K.
Deposit date:2015-08-31
Release date:2015-09-16
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (2.43 Å)
Cite:Mechanism-Based Post-Translational Modification and Inactivation in Terpene Synthases.
Acs Chem.Biol., 10, 2015
6DBY
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CRYSTAL STRUCTURE OF NUDIX 1 FROM ARABIDOPSIS THALIANA
Descriptor:Nudix hydrolase 1, MAGNESIUM ION
Authors:Noel, J.P., Thomas, S.T., Dudareva, N., Henry, L.K.
Deposit date:2018-05-03
Release date:2018-09-19
Method:X-RAY DIFFRACTION (2 Å)
Cite:Contribution of isopentenyl phosphate to plant terpenoid metabolism.
Nat Plants, 4, 2018
6DBZ
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CRYSTAL STRUCTURE OF NUDIX 1 FROM ARABIDOPSIS THALIANA COMPLEXED WITH ISOPENTENYL DIPHOSPHATE
Descriptor:Nudix hydrolase 1, ISOPENTYL PYROPHOSPHATE, MAGNESIUM ION
Authors:Noel, J.P., Thomas, S.T., Dudareva, N., Henry, L.K.
Deposit date:2018-05-03
Release date:2018-09-19
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Contribution of isopentenyl phosphate to plant terpenoid metabolism.
Nat Plants, 4, 2018
6N0X
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CRYSTAL STRUCTURE OF ANAEROLINEA THERMOPHILA MEVALONATE 5-PHOSPHATE DECARBOXYLASE COMPLEXED WITH (R)-MVAP
Descriptor:Diphosphomevalonate decarboxylase, (3R)-3-HYDROXY-3-METHYL-5-(PHOSPHONOOXY)PENTANOIC ACID
Authors:Noel, J.P., Thomas, S.T., Louie, G.V.
Deposit date:2018-11-07
Release date:2019-07-17
Method:X-RAY DIFFRACTION (1.44 Å)
Cite:Substrate specificity and engineering of mevalonate 5-phosphate decarboxylase.
Acs Chem.Biol., 2019