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1CDW
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BU of 1cdw by Molmil
HUMAN TBP CORE DOMAIN COMPLEXED WITH DNA
Descriptor: DNA (5'-D(*CP*AP*GP*CP*CP*TP*TP*TP*TP*AP*TP*AP*GP*CP*AP*G)-3'), DNA (5'-D(*CP*TP*GP*CP*TP*AP*TP*AP*AP*AP*AP*GP*GP*CP*TP*G)-3'), PROTEIN (TATA BINDING PROTEIN (TBP))
Authors:Nikolov, D.B, Chen, H, Halay, E.D, Hoffmann, A, Roeder, R.G, Burley, S.K.
Deposit date:1996-04-11
Release date:1996-12-23
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of a human TATA box-binding protein/TATA element complex.
Proc.Natl.Acad.Sci.USA, 93, 1996
1VOK
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BU of 1vok by Molmil
ARABIDOPSIS THALIANA TBP (DIMER)
Descriptor: SULFATE ION, TATA-BOX-BINDING PROTEIN
Authors:Nikolov, D.B, Burley, S.K.
Deposit date:1996-04-29
Release date:1996-11-08
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:2.1 A resolution refined structure of a TATA box-binding protein (TBP).
Nat.Struct.Biol., 1, 1994
1VOL
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BU of 1vol by Molmil
TFIIB (HUMAN CORE DOMAIN)/TBP (A.THALIANA)/TATA ELEMENT TERNARY COMPLEX
Descriptor: DNA (5'-D(*CP*AP*GP*CP*CP*CP*TP*TP*TP*TP*AP*TP*AP*GP*CP*C)-3'), DNA (5'-D(*GP*GP*CP*TP*AP*TP*AP*AP*AP*AP*GP*GP*GP*CP*TP*G)-3'), PROTEIN (TATA BINDING PROTEIN (TBP)), ...
Authors:Nikolov, D.B, Chen, H, Halay, E.D, Usheva, A.U, Hisatake, K, Lee, D.K, Roeder, R.G, Burley, S.K.
Deposit date:1996-04-29
Release date:1996-11-08
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of a TFIIB-TBP-TATA-element ternary complex.
Nature, 377, 1995
8GH4
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BU of 8gh4 by Molmil
Complex of Adam 10 disentegrin cysteine rich domains with human monoclonal antibody
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody heavy chain, Antibody light chain, ...
Authors:Nikolov, D.B, Saha, N, Xu, K, Goldgur, Y.
Deposit date:2023-03-09
Release date:2023-08-30
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Fully human monoclonal antibody targeting activated ADAM10 on colorectal cancer cells.
Biomed Pharmacother, 161, 2023
7S7K
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BU of 7s7k by Molmil
Crystal structure of the EphB2 extracellular domain
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ephrin type-B receptor 2, ...
Authors:Xu, Y, Xu, K, Nikolov, D.B.
Deposit date:2021-09-16
Release date:2021-10-27
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:The Ephb2 Receptor Uses Homotypic, Head-to-Tail Interactions within Its Ectodomain as an Autoinhibitory Control Mechanism.
Int J Mol Sci, 22, 2021
5L0Q
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BU of 5l0q by Molmil
Crystal structure of the complex between ADAM10 D+C domain and a conformation specific mAb 8C7.
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Disintegrin and metalloproteinase domain-containing protein 10, MAGNESIUM ION, ...
Authors:Xu, K, Saha, N, Nikolov, D.B.
Deposit date:2016-07-28
Release date:2016-11-09
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.759 Å)
Cite:An activated form of ADAM10 is tumor selective and regulates cancer stem-like cells and tumor growth.
J.Exp.Med., 213, 2016
5EVM
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BU of 5evm by Molmil
Crystal Structure of Nipah Virus Fusion Glycoprotein in the Prefusion State
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0, MALONATE ION, ...
Authors:Xu, K, Nikolov, D.B.
Deposit date:2015-11-20
Release date:2015-12-16
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.367 Å)
Cite:Crystal Structure of the Pre-fusion Nipah Virus Fusion Glycoprotein Reveals a Novel Hexamer-of-Trimers Assembly.
Plos Pathog., 11, 2015
1FVI
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BU of 1fvi by Molmil
CRYSTAL STRUCTURE OF CHLORELLA VIRUS DNA LIGASE-ADENYLATE
Descriptor: ADENOSINE MONOPHOSPHATE, CHLORELLA VIRUS DNA LIGASE-ADENYLATE, SULFATE ION
Authors:Odell, M, Sriskanda, V, Shuman, S, Nikolov, D.B.
Deposit date:2000-09-20
Release date:2000-11-22
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of eukaryotic DNA ligase-adenylate illuminates the mechanism of nick sensing and strand joining.
Mol.Cell, 6, 2000
6PD4
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BU of 6pd4 by Molmil
Crystal Structure of Hendra Virus Attachment G Glycoprotein
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Attachment glycoprotein, ...
Authors:Xu, K, Nikolov, D.B.
Deposit date:2019-06-18
Release date:2019-11-27
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:New insights into the Hendra virus attachment and entry process from structures of the virus G glycoprotein and its complex with Ephrin-B2.
PLoS ONE, 7, 2012
6PDL
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BU of 6pdl by Molmil
Crystal Structure of Hendra Virus Attachment G Glycoprotein in Complex with Receptor Ephrin-B2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Attachment glycoprotein, ...
Authors:Xu, K, Nikolov, D.B.
Deposit date:2019-06-19
Release date:2019-11-27
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:New insights into the Hendra virus attachment and entry process from structures of the virus G glycoprotein and its complex with Ephrin-B2.
PLoS ONE, 7, 2012
2GY5
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BU of 2gy5 by Molmil
Tie2 Ligand-Binding Domain Crystal Structure
Descriptor: 2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiopoietin-1 receptor, ...
Authors:Barton, W.A, Nikolov, D.B.
Deposit date:2006-05-09
Release date:2006-06-06
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structures of the Tie2 receptor ectodomain and the angiopoietin-2-Tie2 complex.
Nat.Struct.Mol.Biol., 13, 2006
2GY7
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BU of 2gy7 by Molmil
Angiopoietin-2/Tie2 Complex Crystal Structure
Descriptor: 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Barton, W.A, Nikolov, D.B.
Deposit date:2006-05-09
Release date:2006-06-06
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:Crystal structures of the Tie2 receptor ectodomain and the angiopoietin-2-Tie2 complex.
Nat.Struct.Mol.Biol., 13, 2006
3MX0
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BU of 3mx0 by Molmil
Crystal Structure of EphA2 ectodomain in complex with ephrin-A5
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ephrin type-A receptor 2, ...
Authors:Himanen, J.P, Yermekbayeva, L, Janes, P.W, Walker, J.R, Xu, K, Atapattu, L, Rajashankar, K.R, Mensinga, A, Lackmann, M, Nikolov, D.B, Dhe-Paganon, S.
Deposit date:2010-05-06
Release date:2010-06-30
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3.506 Å)
Cite:Architecture of Eph receptor clusters.
Proc.Natl.Acad.Sci.USA, 107, 2010
3HEI
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BU of 3hei by Molmil
Ligand Recognition by A-Class Eph Receptors: Crystal Structures of the EphA2 Ligand-Binding Domain and the EphA2/ephrin-A1 Complex
Descriptor: Ephrin type-A receptor 2, Ephrin-A1
Authors:Himanen, J.P, Goldgur, Y, Miao, H, Myshkin, E, Guo, H, Buck, M, Nguyen, M, Rajashankar, K.R, Wang, B, Nikolov, D.B.
Deposit date:2009-05-08
Release date:2009-06-30
Last modified:2021-03-31
Method:X-RAY DIFFRACTION (2 Å)
Cite:Ligand recognition by A-class Eph receptors: crystal structures of the EphA2 ligand-binding domain and the EphA2/ephrin-A1 complex.
Embo Rep., 10, 2009
3HPN
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BU of 3hpn by Molmil
Ligand recognition by A-class EPH receptors: crystal structures of the EPHA2 ligand-binding domain and the EPHA2/EPHRIN-A1 complex
Descriptor: Ephrin type-A receptor 2
Authors:Himanen, J.P, Goldgur, Y, Miao, H, Myshkin, E, Guo, H, Buck, M, Nguyen, M, Rajashankar, K.R, Wang, B, Nikolov, D.B.
Deposit date:2009-06-04
Release date:2009-06-30
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.52 Å)
Cite:Ligand recognition by A-class Eph receptors: crystal structures of the EphA2 ligand-binding domain and the EphA2/ephrin-A1 complex.
Embo Rep., 10, 2009
4JYO
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BU of 4jyo by Molmil
Structural basis for angiopoietin-1 mediated signaling initiation
Descriptor: Angiopoietin-1, CALCIUM ION
Authors:Yu, X, Seegar, T.C.M, Dalton, A.C, Tzvetkova-Robev, D, Goldgur, Y, Nikolov, D.B, Barton, W.A.
Deposit date:2013-03-31
Release date:2013-05-08
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis for angiopoietin-1-mediated signaling initiation.
Proc.Natl.Acad.Sci.USA, 110, 2013
4JZC
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BU of 4jzc by Molmil
Angiopoietin-2 fibrinogen domain TAG mutant
Descriptor: Angiopoietin-2
Authors:Yu, X, Seegar, T.C.M, Dalton, A.C, Tzvetkova-Robev, D, Goldgur, Y, Nikolov, D.B, Barton, W.A.
Deposit date:2013-04-02
Release date:2013-05-08
Last modified:2013-05-15
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural basis for angiopoietin-1-mediated signaling initiation.
Proc.Natl.Acad.Sci.USA, 110, 2013
4K0V
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BU of 4k0v by Molmil
Structural basis for angiopoietin-1 mediated signaling initiation
Descriptor: Angiopoietin-1, TEK tyrosine kinase variant
Authors:Yu, X, Seegar, T.C.M, Dalton, A.C, Tzvetkova-Robev, D, Goldgur, Y, Nikolov, D.B, Barton, W.A.
Deposit date:2013-04-04
Release date:2013-05-08
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (4.51 Å)
Cite:Structural basis for angiopoietin-1-mediated signaling initiation.
Proc.Natl.Acad.Sci.USA, 110, 2013
6P72
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BU of 6p72 by Molmil
Crystal Structure of the Cedar henipavirus Attachment G Glycoprotein global domain
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Attachment glycoprotein, ...
Authors:Xu, K, Nikolov, D.B, Xu, Y.
Deposit date:2019-06-04
Release date:2019-09-25
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3.283 Å)
Cite:Structural and functional analyses reveal promiscuous and species specific use of ephrin receptors by Cedar virus.
Proc.Natl.Acad.Sci.USA, 116, 2019
6P7S
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BU of 6p7s by Molmil
Crystal Structure of the Cedar henipavirus Attachment G Glycoprotein globular domain in complex with the receptor ephrin-B1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Attachment glycoprotein, ...
Authors:Xu, K, Nikolov, D.B, Xu, Y.
Deposit date:2019-06-06
Release date:2019-09-25
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3.49 Å)
Cite:Structural and functional analyses reveal promiscuous and species specific use of ephrin receptors by Cedar virus.
Proc.Natl.Acad.Sci.USA, 116, 2019
6P7Y
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BU of 6p7y by Molmil
Crystal Structure of the Cedar henipavirus Attachment G Glycoprotein globular domain in complex with the receptor ephrin-B2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Attachment glycoprotein, ...
Authors:Xu, K, Nikolov, D.B, Xu, Y.
Deposit date:2019-06-06
Release date:2019-09-25
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.844 Å)
Cite:Structural and functional analyses reveal promiscuous and species specific use of ephrin receptors by Cedar virus.
Proc.Natl.Acad.Sci.USA, 116, 2019
1SHX
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BU of 1shx by Molmil
Ephrin A5 ligand structure
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ephrin-A5
Authors:Himanen, J.P, Barton, W.A, Nikolov, D.B, Jeffrey, P.D.
Deposit date:2004-02-26
Release date:2005-04-19
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Three distinct molecular surfaces in ephrin-A5 are essential for a functional interaction with EphA3.
J.Biol.Chem., 280, 2005
1Z3U
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BU of 1z3u by Molmil
Structure of the Angiopoietin-2 Recptor Binding Domain and Identification of Surfaces Involved in Tie2 Recognition
Descriptor: Angiopoietin-2, CALCIUM ION
Authors:Barton, W.A, Tzvetkova, D, Nikolov, D.B.
Deposit date:2005-03-14
Release date:2005-07-12
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structure of the angiopoietin-2 receptor binding domain and identification of surfaces involved in Tie2 recognition.
Structure, 13, 2005
1Z3S
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BU of 1z3s by Molmil
Angiopoietin-2 Receptor Binding Domain
Descriptor: Angiopoietin-2, CALCIUM ION
Authors:Barton, W.A, Tzvetkova, D, Nikolov, D.B.
Deposit date:2005-03-14
Release date:2005-07-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structure of the angiopoietin-2 receptor binding domain and identification of surfaces involved in Tie2 recognition.
Structure, 13, 2005
2AO7
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BU of 2ao7 by Molmil
Adam10 Disintegrin and cysteine- rich domain
Descriptor: ADAM 10, SULFATE ION
Authors:Janes, P.W, Saha, N, Barton, W.A, Kolev, M.V, Wimmer-Kleikamp, S.H, Nievergall, E, Blobel, C.P, Himanen, J.-P, Lackmann, M, Nikolov, D.B.
Deposit date:2005-08-12
Release date:2006-08-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Adam meets Eph: an ADAM substrate recognition module acts as a molecular switch for ephrin cleavage in trans.
Cell(Cambridge,Mass.), 123, 2005

 

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