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3LAJ
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THE STRUCTURE OF THE INTERMEDIATE COMPLEX OF THE ARGININE REPRESSOR FROM MYCOBACTERIUM TUBERCULOSIS BOUND TO ITS DNA OPERATOR AND L-ARGININE.
分子名称:Arginine repressor, 5'-D(*TP*TP*GP*CP*AP*TP*AP*AP*CP*GP*AP*TP*GP*CP*AP*A)-3', 5'-D(*TP*TP*GP*CP*AP*TP*CP*GP*TP*TP*AP*TP*GP*CP*AP*A)-3', ...
著者Cherney, L.T., Cherney, M.M., Garen, C.R., James, M.N.G., Mycobacterium Tuberculosis Structural Proteomics Project (XMTB)
登録日2010-01-06
公開日2010-05-05
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.306 Å)
主引用文献crystal structure of the intermediate complex of the arginine repressor from Mycobacterium tuberculosis bound with its DNA operator reveals detailed mechanism of arginine repression.
J.Mol.Biol., 399, 2010
3KGF
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THE STRUCTURE OF 3-DEOXY-D-ARABINO-HEPTULOSONATE 7-PHOSPHATE SYNTHASE FROM MYCOBACTERIUM TUBERCULOSIS COMPLEXED WITH PHENYLALANINE AND TRYPTOPHAN
分子名称:Probable 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase AroG, PHENYLALANINE, TRYPTOPHAN, ...
著者Parker, E.J., Jameson, G.B., Jiao, W., Webby, C.J., Baker, E.N., Baker, H.M., Mycobacterium Tuberculosis Structural Proteomics Project (XMTB)
登録日2009-10-29
公開日2010-07-28
最終更新日2012-02-22
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Synergistic allostery, a sophisticated regulatory network for the control of aromatic amino acid biosynthesis in Mycobacterium tuberculosis
J.Biol.Chem., 285, 2010
1Z8F
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GUANYLATE KINASE DOUBLE MUTANT A58C, T157C FROM MYCOBACTERIUM TUBERCULOSIS (RV1389)
分子名称:Guanylate kinase, FORMIC ACID
著者Chan, S., Sawaya, M.R., Choi, B., Zocchi, G., Perry, L.J., Mycobacterium Tuberculosis Structural Proteomics Project (XMTB)
登録日2005-03-30
公開日2005-04-12
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal Structure of Guanylate Kinase from Mycobacterium tuberculosis (Rv1389)
To be Published
2A2J
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CRYSTAL STRUCTURE OF A PUTATIVE PYRIDOXINE 5'-PHOSPHATE OXIDASE (RV2607) FROM MYCOBACTERIUM TUBERCULOSIS
分子名称:Pyridoxamine 5'-phosphate oxidase
著者Pedelacq, J.-D., Rho, B.-S., Kim, C.-Y., Waldo, G.S., Lekin, T.P., Segelke, B.W., Rupp, B., Hung, L.-W., Kim, S.-I., Terwilliger, T.C., Mycobacterium Tuberculosis Structural Proteomics Project (XMTB)
登録日2005-06-22
公開日2005-08-23
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of a putative pyridoxine 5'-phosphate oxidase (Rv2607) from Mycobacterium tuberculosis.
Proteins, 62, 2005
2B7O
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THE STRUCTURE OF 3-DEOXY-D-ARABINO-HEPTULOSONATE 7-PHOSPHATE SYNTHASE FROM MYCOBACTERIUM TUBERCULOSIS
分子名称:3-deoxy-D-arabino-heptulosonate 7-phosphate synthase AroG, MANGANESE (II) ION, SULFATE ION, ...
著者Webby, C.J., Baker, H.M., Lott, J.S., Baker, E.N., Parker, E.J., Mycobacterium Tuberculosis Structural Proteomics Project (XMTB)
登録日2005-10-05
公開日2005-10-18
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The structure of 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase from Mycobacterium tuberculosis reveals a common catalytic scaffold and ancestry for type I and type II enzymes
J.Mol.Biol., 354, 2005
2E3J
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THE CRYSTAL STRUCTURE OF EPOXIDE HYDROLASE B (RV1938) FROM MYCOBACTERIUM TUBERCULOSIS AT 2.1 ANGSTROM
分子名称:EPOXIDE HYDROLASE EPHB, ACETATE ION
著者Biswal, B.K., Mycobacterium Tuberculosis Structural Proteomics Project (XMTB)
登録日2006-11-27
公開日2007-12-04
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The molecular structure of epoxide hydrolase B from Mycobacterium tuberculosis and its complex with a urea-based inhibitor.
J.Mol.Biol., 381, 2008
2FYF
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STRUCTURE OF A PUTATIVE PHOSPHOSERINE AMINOTRANSFERASE FROM MYCOBACTERIUM TUBERCULOSIS
分子名称:phosphoserine aminotransferase, SULFATE ION, TETRACHLOROPLATINATE(II), ...
著者Coulibaly, F., Lassalle, E., Baker, E.N., Mycobacterium Tuberculosis Structural Proteomics Project (XMTB)
登録日2006-02-07
公開日2007-01-16
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structure of phosphoserine aminotransferase from Mycobacterium tuberculosis.
Acta Crystallogr.,Sect.D, 68, 2012
2I3A
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CRYSTAL STRUCTURE OF N-ACETYL-GAMMA-GLUTAMYL-PHOSPHATE REDUCTASE (RV1652) FROM MYCOBACTERIUM TUBERCULOSIS
分子名称:N-acetyl-gamma-glutamyl-phosphate reductase, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL
著者Cherney, L.T., Cherney, M.M., Garen, C.R., Moraidin, F., James, M.N.G., Mycobacterium Tuberculosis Structural Proteomics Project (XMTB)
登録日2006-08-17
公開日2006-08-29
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Crystal Structure of N-acetyl-gamma-glutamyl-phosphate Reductase from Mycobacterium tuberculosis in Complex with NADP(+).
J.Mol.Biol., 367, 2007
2I3G
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CRYSTAL STRUCTURE OF N-ACETYL-GAMMA-GLUTAMYL-PHOSPHATE REDUCTASE (RV1652) FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH NADP+.
分子名称:N-acetyl-gamma-glutamyl-phosphate reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL
著者Cherney, L.T., Cherney, M.M., Garen, C.R., Moraidin, F., James, M.N.G., Mycobacterium Tuberculosis Structural Proteomics Project (XMTB), TB Structural Genomics Consortium (TBSGC)
登録日2006-08-18
公開日2006-09-05
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Crystal Structure of N-acetyl-gamma-glutamyl-phosphate Reductase from Mycobacterium tuberculosis in Complex with NADP(+).
J.Mol.Biol., 367, 2007
2O2E
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MYCOBACTERIUM TUBERCULOSIS TRYPTOPHAN SYNTHASE BETA SUBUNIT DIMER (APOFORM)
分子名称:Tryptophan synthase beta chain
著者Burenkov, G.P., Kachalova, G.S., Bartunik, H.D., Mycobacterium Tuberculosis Structural Proteomics Project (XMTB)
登録日2006-11-29
公開日2008-04-08
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure Tryptophan SYNTHASE beta subunit dimer from MYCOBACTERIUM TUBERCULOSIS
To be Published
2O2J
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MYCOBACTERIUM TUBERCULOSIS TRYPTOPHAN SYNTHASE BETA CHAIN DIMER (APOFORM)
分子名称:Tryptophan synthase beta chain
著者Burenkov, G.P., Kachalova, G.S., Bartunik, H.D., Mycobacterium Tuberculosis Structural Proteomics Project (XMTB)
登録日2006-11-29
公開日2008-04-08
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (2.56 Å)
主引用文献Structure Tryptophan SYNTHASE beta chain dimer from MYCOBACTERIUM Tuberculosis
To be Published
3NE3
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MYCOBACTERIUM TUBERCULOSIS ACYL CARRIER PROTEIN SYNTHASE APO STRUCTURE
分子名称:Holo-[acyl-carrier-protein] synthase
著者Gokulan, K., Mycobacterium Tuberculosis Structural Proteomics Project (XMTB)
登録日2010-06-08
公開日2010-07-28
最終更新日2019-07-17
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Mycobacterium tuberculosis acyl carrier protein synthase adopts two different pH-dependent structural conformations.
Acta Crystallogr.,Sect.D, 67, 2011
4JAO
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CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS PKS11 REVEALS INTERMEDIATES IN THE SYNTHESIS OF METHYL-BRANCHED ALKYLPYRONES
分子名称:Alpha-pyrone synthesis polyketide synthase-like Pks11, PALMITIC ACID, (2S)-2-methylheptadecan-1-ol
著者Gokulan, K., Sacchettini, J.C., Mycobacterium Tuberculosis Structural Proteomics Project (XMTB)
登録日2013-02-18
公開日2013-04-24
最終更新日2013-11-27
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Crystal structure of Mycobacterium tuberculosis polyketide synthase 11 (PKS11) reveals intermediates in the synthesis of methyl-branched alkylpyrones.
J.Biol.Chem., 288, 2013
4JAP
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CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS PKS11 REVEALS INTERMEDIATES IN THE SYNTHESIS OF METHYL-BRANCHED ALKYLPYRONES
分子名称:Alpha-pyrone synthesis polyketide synthase-like Pks11, PALMITIC ACID, COENZYME A, ...
著者Gokulan, K., Sacchettini, J.C., Mycobacterium Tuberculosis Structural Proteomics Project (XMTB)
登録日2013-02-19
公開日2013-04-24
最終更新日2013-11-27
実験手法X-RAY DIFFRACTION (1.833 Å)
主引用文献Crystal structure of Mycobacterium tuberculosis polyketide synthase 11 (PKS11) reveals intermediates in the synthesis of methyl-branched alkylpyrones.
J.Biol.Chem., 288, 2013
4JAQ
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CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS PKS11 REVEALS INTERMEDIATES IN THE SYNTHESIS OF METHYL-BRANCHED ALKYLPYRONES
分子名称:Alpha-pyrone synthesis polyketide synthase-like Pks11, 3,5-dioxoicosanoic acid, COENZYME A, ...
著者Gokulan, K., Sacchettini, J.C., Mycobacterium Tuberculosis Structural Proteomics Project (XMTB)
登録日2013-02-19
公開日2013-04-24
最終更新日2013-11-27
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献Crystal structure of Mycobacterium tuberculosis polyketide synthase 11 (PKS11) reveals intermediates in the synthesis of methyl-branched alkylpyrones.
J.Biol.Chem., 288, 2013
4JAR
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CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS PKS11 IN COMPLEX WITH POLYKETIDE INTERMEDIATES AND EVIDENCE THAT IT SYNTHESIZE ALKYLPYRONES
分子名称:Alpha-pyrone synthesis polyketide synthase-like Pks11
著者Gokulan, K., Sacchettini, J.C., Mycobacterium Tuberculosis Structural Proteomics Project (XMTB)
登録日2013-02-19
公開日2013-04-24
最終更新日2013-11-27
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献Crystal structure of Mycobacterium tuberculosis polyketide synthase 11 (PKS11) reveals intermediates in the synthesis of methyl-branched alkylpyrones.
J.Biol.Chem., 288, 2013
4JAT
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CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS PKS11 REVEALS INTERMEDIATES IN THE SYNTHESIS OF METHYL-BRANCHED ALKYLPYRONES
分子名称:Alpha-pyrone synthesis polyketide synthase-like Pks11, PALMITIC ACID
著者Gokulan, K., Sacchettini, J.C., Mycobacterium Tuberculosis Structural Proteomics Project (XMTB)
登録日2013-02-19
公開日2013-04-24
最終更新日2014-05-21
実験手法X-RAY DIFFRACTION (2.42 Å)
主引用文献Crystal structure of Mycobacterium tuberculosis polyketide synthase 11 (PKS11) reveals intermediates in the synthesis of methyl-branched alkylpyrones.
J.Biol.Chem., 288, 2013
4JD3
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CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS PKS11 REVEALS INTERMEDIATES IN THE SYNTHESIS OF METHYL-BRANCHED ALKYLPYRONES
分子名称:Alpha-pyrone synthesis polyketide synthase-like Pks11, PALMITIC ACID, COENZYME A
著者Gokulan, K., Sacchettini, J.C., Mycobacterium Tuberculosis Structural Proteomics Project (XMTB)
登録日2013-02-22
公開日2013-04-24
最終更新日2014-05-21
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Crystal structure of Mycobacterium tuberculosis polyketide synthase 11 (PKS11) reveals intermediates in the synthesis of methyl-branched alkylpyrones.
J.Biol.Chem., 288, 2013
5CYY
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STRUCTURE OF THE C-TERMINAL DOMAINS OF DIPZ FROM MYCOBACTERIUM TUBERCULOSIS
分子名称:Protein DipZ
著者Goldstone, D.C., Metcalf, P., Baker, E.N., Mycobacterium Tuberculosis Structural Proteomics Project (XMTB)
登録日2015-07-31
公開日2016-01-13
最終更新日2018-04-18
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure of the ectodomain of the electron transporter Rv2874 from Mycobacterium tuberculosis reveals a thioredoxin-like domain combined with a carbohydrate-binding module.
Acta Crystallogr D Struct Biol, 72, 2016
1YS6
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CRYSTAL STRUCTURE OF THE RESPONSE REGULATORY PROTEIN PRRA FROM MYCOBACTERIUM TUBERCULOSIS
分子名称:Transcriptional regulatory protein prrA, CALCIUM ION, GLYCEROL
著者Nowak, E., Panjikar, S., Tucker, P., Mycobacterium Tuberculosis Structural Proteomics Project (XMTB)
登録日2005-02-07
公開日2006-02-07
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献Crystal structure of the response regulatory protein PrrA from Mycobacterium Tuberculosis
To be published
1YS7
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CRYSTAL STRUCTURE OF THE RESPONSE REGULATOR PROTEIN PRRA COMPLEXED WITH MG2+
分子名称:Transcriptional regulatory protein prrA, MAGNESIUM ION, ACETATE ION, ...
著者Nowak, E., Panjikar, S., Tucker, P., Mycobacterium Tuberculosis Structural Proteomics Project (XMTB)
登録日2005-02-07
公開日2006-02-07
最終更新日2016-12-28
実験手法X-RAY DIFFRACTION (1.58 Å)
主引用文献The structural basis of signal transduction for the response regulator PrrA from Mycobacterium tuberculosis.
J.Biol.Chem., 281, 2006
1YSR
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CRYSTAL STRUCTURE OF ATP BINDING DOMAIN OF PRRB FROM MYCOBACTERIUM TUBERCULOSIS
分子名称:Sensor-type histidine kinase prrB, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLYCEROL
著者Nowak, E., Panjikar, S., Tucker, P., Mycobacterium Tuberculosis Structural Proteomics Project (XMTB)
登録日2005-02-09
公開日2005-07-12
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Crystal Structure of ATP binding domain of PrrB from Mycobacterium Tuberculosis
To be published
1Z9W
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TETRAMERIC STRUCTURE OF APO-7,8-DIHYDRONEOPTERIN ALDOLASE FROM MYCOBACTERIUM TUBERCULOSIS
分子名称:Dihydroneopterin aldolase
著者Goulding, C.W., Apostol, M.I., Sawaya, M.R., Philips, M., Parseghian, A., Eisenberg, D., Mycobacterium Tuberculosis Structural Proteomics Project (XMTB)
登録日2005-04-05
公開日2005-04-19
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Regulation by oligomerization in a mycobacterial folate biosynthetic enzyme.
J.Mol.Biol., 349, 2005
2A11
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CRYSTAL STRUCTURE OF NUCLEASE DOMAIN OF RIBONUCLASE III FROM MYCOBACTERIUM TUBERCULOSIS
分子名称:Ribonuclease III, CALCIUM ION
著者Akey, D.L., Berger, J.M., Mycobacterium Tuberculosis Structural Proteomics Project (XMTB)
登録日2005-06-17
公開日2005-07-05
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structure of the nuclease domain of ribonuclease III from M. tuberculosis at 2.1 A
Protein Sci., 14, 2005
6DNP
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CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS MALATE SYNTHASE IN COMPLEX WITH 2-F-3-METHYL-6-F-PHENYLDIKETOACID
分子名称:Malate synthase G, MAGNESIUM ION, (2Z)-4-(2,6-difluoro-3-methylphenyl)-2-hydroxy-4-oxobut-2-enoic acid, ...
著者Krieger, I.V., Sacchettini, J.C., TB Structural Genomics Consortium (TBSGC), Mycobacterium Tuberculosis Structural Proteomics Project (XMTB)
登録日2018-06-07
公開日2018-09-05
最終更新日2018-10-31
実験手法X-RAY DIFFRACTION (1.711 Å)
主引用文献Anion-pi Interactions in Computer-Aided Drug Design: Modeling the Inhibition of Malate Synthase by Phenyl-Diketo Acids.
J Chem Inf Model, 58, 2018
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