1ZLB
| Crystal structure of catalytically-active phospholipase A2 in the absence of calcium | Descriptor: | hypotensive phospholipase A2 | Authors: | Murakami, M.T, Cintra, A.C, Gabdoulkhakov, A, Genov, N, Betzel, C, Arni, R.K. | Deposit date: | 2005-05-05 | Release date: | 2006-04-25 | Last modified: | 2017-10-11 | Method: | X-RAY DIFFRACTION (0.97 Å) | Cite: | Insights into metal ion binding in phospholipases A(2): ultra high-resolution crystal structures of an acidic phospholipase A(2) in the Ca(2+) free and bound states. Biochimie, 88, 2006
|
|
1ZL7
| Crystal structure of catalytically-active phospholipase A2 with bound calcium | Descriptor: | CALCIUM ION, GLYCEROL, hypotensive phospholipase A2 | Authors: | Murakami, M.T, Cintra, A.C, Gabdoulkhakov, A, Genov, N, Betzel, C, Arni, R.K. | Deposit date: | 2005-05-05 | Release date: | 2006-04-25 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Insights into metal ion binding in phospholipases A(2): ultra high-resolution crystal structures of an acidic phospholipase A(2) in the Ca(2+) free and bound states. Biochimie, 88, 2006
|
|
2AIQ
| |
2AIP
| |
2F9R
| Crystal structure of the inactive state of the Smase I, a sphingomyelinase D from Loxosceles laeta venom | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, MAGNESIUM ION, Sphingomyelinase D 1 | Authors: | Murakami, M.T, Gabdoulkhakov, A, Fernandes-Pedrosa, M.F, Betzel, C, Tambourgi, D.V, Arni, R.K. | Deposit date: | 2005-12-06 | Release date: | 2006-06-27 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Structural basis for metal ion coordination and the catalytic mechanism of sphingomyelinases D. J.Biol.Chem., 280, 2005
|
|
2H8I
| |
2H8U
| |
2H9E
| Crystal Structure of FXa/selectide/NAPC2 ternary complex | Descriptor: | ACETATE ION, Anti-coagulant protein C2, Coagulation factor X heavy chain, ... | Authors: | Murakami, M.T, Geiger, G, Tulinsky, A, Arni, R.K. | Deposit date: | 2006-06-09 | Release date: | 2007-02-13 | Last modified: | 2017-10-18 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Intermolecular Interactions and Characterization of the Novel Factor Xa Exosite Involved in Macromolecular Recognition and Inhibition: Crystal Structure of Human Gla-domainless Factor Xa Complexed with the Anticoagulant Protein NAPc2 from the Hematophagous Nematode Ancylostoma caninum. J.Mol.Biol., 366, 2007
|
|
1UMR
| Crystal structure of the platelet activator convulxin, a disulfide linked a4b4 cyclic tetramer from the venom of Crotalus durissus terrificus | Descriptor: | CONVULXIN ALPHA, CONVULXIN BETA | Authors: | Murakami, M.T, Zela, S.P, Gava, L.M, Michelan-Duarte, S, Cintra, A.C.O, Arni, R.K. | Deposit date: | 2003-08-28 | Release date: | 2003-11-21 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal Structure of the Platelet Activator Convulxin, a Disulfide Linked A4B4 Cyclic Tetramer from the Venom of Crotalus Durissus Terrificus Biochem.Biophys.Res.Commun., 310, 2003
|
|
1XX1
| Structural basis for ion-coordination and the catalytic mechanism of sphingomyelinases D | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, MAGNESIUM ION, SULFATE ION, ... | Authors: | Murakami, M.T, Tambourgi, D.V, Arni, R.K. | Deposit date: | 2004-11-03 | Release date: | 2005-01-18 | Last modified: | 2017-10-11 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Structural basis for metal ion coordination and the catalytic mechanism of sphingomyelinases d J.Biol.Chem., 280, 2005
|
|
2PH4
| Crystal structure of a novel Arg49 phospholipase A2 homologue from Zhaoermia mangshanensis venom | Descriptor: | DI(HYDROXYETHYL)ETHER, SULFATE ION, Zhaoermiatoxin | Authors: | Murakami, M.T, Kuch, U, Mebs, D, Arni, R.K. | Deposit date: | 2007-04-10 | Release date: | 2008-03-18 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Crystal structure of a novel myotoxic Arg49 phospholipase A(2) homolog (zhaoermiatoxin) from Zhaoermia mangshanensis snake venom: Insights into Arg49 coordination and the role of Lys122 in the polarization of the C-terminus. Toxicon, 51, 2008
|
|
1XXN
| Crystal structure of a mesophilic xylanase A from Bacillus subtilis 1A1 | Descriptor: | Endo-1,4-beta-xylanase A, S,R MESO-TARTARIC ACID | Authors: | Murakami, M.T, Ruller, R, Ward, R.J, Arni, R.K. | Deposit date: | 2004-11-07 | Release date: | 2005-10-18 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Correlation of temperature induced conformation change with optimum catalytic activity in the recombinant G/11 xylanase A from Bacillus subtilis strain 168 (1A1). Febs Lett., 579, 2005
|
|
1Y4L
| Crystal structure of Bothrops asper myotoxin II complexed with the anti-trypanosomal drug suramin | Descriptor: | 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, 8,8'-[CARBONYLBIS[IMINO-3,1-PHENYLENECARBONYLIMINO(4-METHYL-3,1-PHENYLENE)CARBONYLIMINO]]BIS-1,3,5-NAPHTHALENETRISULFONIC ACID, ISOPROPYL ALCOHOL, ... | Authors: | Murakami, M.T, Arruda, E.Z, Melo, P.A, Martinez, A.B, Calil-Elias, S, Tomaz, M.A, Lomonte, B, Gutierrez, J.M, Arni, R.K. | Deposit date: | 2004-12-01 | Release date: | 2005-06-28 | Last modified: | 2017-10-11 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Inhibition of Myotoxic Activity of Bothrops asper Myotoxin II by the Anti-trypanosomal Drug Suramin. J.Mol.Biol., 350, 2005
|
|
4E2D
| Structure of the old yellow enzyme from Trypanosoma cruzi | Descriptor: | DIMETHYL SULFOXIDE, FLAVIN MONONUCLEOTIDE, Old Yellow Protein | Authors: | Murakami, M.T, Rodrigues, N.C, Gava, L.M, Canduri, F, Oliva, G, Barbosa, L.R.S, Borgers, J.C. | Deposit date: | 2012-03-08 | Release date: | 2013-03-27 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.997 Å) | Cite: | High resolution crystal structure and in solution studies of the Old Yellow Enzyme from Trypanosoma cruzi: Insights into oligomerization, enzyme dynamics and specificity To be Published
|
|
4E2B
| High resolution crystal structure of the old yellow enzyme from Trypanosoma cruzi | Descriptor: | DI(HYDROXYETHYL)ETHER, FLAVIN MONONUCLEOTIDE, GLYCEROL, ... | Authors: | Murakami, M.T, Rodrigues, N.C, Gava, L.M, Canduri, F, Oliva, G, Barbosa, L.R.S, Borgers, J.C. | Deposit date: | 2012-03-08 | Release date: | 2013-03-27 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.269 Å) | Cite: | High resolution crystal structure and in solution studies of the old yellow enzyme from Trypanosoma cruzi: Insights into oligomerization, enzyme dynamics and specificity To be Published
|
|
2AOZ
| Crystal structure of the myotoxin-II from Atropoides nummifer venom | Descriptor: | Phospholipase A2 homolog, SULFATE ION | Authors: | Melo, C.C, Murakami, M.T, Angulo, Y, Lomonte, B, Arni, R.K. | Deposit date: | 2005-08-15 | Release date: | 2006-07-25 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.08 Å) | Cite: | Structure of myotoxin II, a catalytically inactive Lys49 phospholipase A2 homologue from Atropoides nummifer venom. Acta Crystallogr.,Sect.F, 62, 2006
|
|
1UMV
| Crystal structure of an acidic, non-myotoxic phospholipase A2 from the venom of Bothrops jararacussu | Descriptor: | CALCIUM ION, HYPOTENSIVE PHOSPHOLIPASE A2 | Authors: | Murakami, M.T, Watanabe, L, Cintra, A.C.O, Arni, R.K. | Deposit date: | 2003-08-28 | Release date: | 2003-09-18 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.79 Å) | Cite: | Crystal Structure of an Acidic Platelet Aggregation Inhibitor and Hypotensive Phospholipase A(2) in the Monomeric and Dimeric States: Insights Into its Oligomeric State Biochem.Biophys.Res.Commun., 323, 2004
|
|
5KB6
| High-resolution structure of the adenosine kinase from Mus musculus in complex with adenosine | Descriptor: | ACETATE ION, ADENOSINE, Adenosine kinase, ... | Authors: | Oliveira, R.R, Neto, R.M, Polo, C.C, Tonoli, C.C.C, Murakami, M.T, Franchini, K.G. | Deposit date: | 2016-06-02 | Release date: | 2017-06-07 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | High-resolution structure of the adenosine kinase from Mus musculus in complex with adenosine To Be Published
|
|
5KB5
| Crystal structure of the adenosine kinase from Mus musculus in complex with adenosine and adenosine-diphosphate | Descriptor: | ADENOSINE, ADENOSINE-5'-DIPHOSPHATE, Adenosine kinase, ... | Authors: | Oliveira, R.R, Neto, R.M, Polo, C.C, Tonoli, C.C.C, Murakami, M.T, Franchini, K.G. | Deposit date: | 2016-06-02 | Release date: | 2017-06-07 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structure of the adenosine kinase from Mus musculus in complex with adenosine and adenosine-diphosphate To Be Published
|
|
8D89
| Crystal structure of a novel GH5 enzyme retrieved from capybara gut metagenome | Descriptor: | 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, ACETATE ION, CHLORIDE ION, ... | Authors: | Martins, M.P, Morais, M.A.B, Murakami, M.T. | Deposit date: | 2022-06-08 | Release date: | 2022-11-02 | Last modified: | 2022-11-16 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Glycoside hydrolase subfamily GH5_57 features a highly redesigned catalytic interface to process complex hetero-beta-mannans. Acta Crystallogr D Struct Biol, 78, 2022
|
|
6MS2
| Crystal structure of the GH43 BlXynB protein from Bacillus licheniformis | Descriptor: | CALCIUM ION, Glycoside Hydrolase Family 43 | Authors: | Zanphorlin, L.M, Morais, M.A.B, Diogo, J.A, Murakami, M.T. | Deposit date: | 2018-10-16 | Release date: | 2019-04-17 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.494 Å) | Cite: | Structure-guided design combined with evolutionary diversity led to the discovery of the xylose-releasing exo-xylanase activity in the glycoside hydrolase family 43. Biotechnol. Bioeng., 116, 2019
|
|
6NDQ
| |
3GBO
| Crystal structure of BmooMPalpha-I, a non-hemorrhagic metalloproteinase isolated from Bothrops moojeni snake venom | Descriptor: | CALCIUM ION, ZINC ION, Zinc metalloproteinase BmooMPalfa-I | Authors: | Akao, P.K, Tonoli, C.C.C, Murakami, M.T. | Deposit date: | 2009-02-20 | Release date: | 2009-09-22 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.77 Å) | Cite: | Structural studies of BmooMPalpha-I, a non-hemorrhagic metalloproteinase from Bothrops moojeni venom. Toxicon, 55, 2010
|
|
3KVE
| Structure of native L-amino acid oxidase from Vipera ammodytes ammodytes: stabilization of the quaternary structure by divalent ions and structural changes in the dynamic active site | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, FLAVIN-ADENINE DINUCLEOTIDE, L-amino acid oxidase, ... | Authors: | Gergiova, D, Murakami, M.T, Perbandt, M, Arni, R.K, Betzel, C. | Deposit date: | 2009-11-30 | Release date: | 2010-10-13 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.57 Å) | Cite: | Structure of native L-amino acid oxidase from Vipera ammodytes ammodytes: stabilization of the quaternary structure by divalent ions and structural changes in the dynamic active site To be Published
|
|
4RW3
| Structural insights into substrate binding of brown spider venom class II phospholipases D | Descriptor: | D-MYO-INOSITOL-1-PHOSPHATE, DECANOIC ACID, DI(HYDROXYETHYL)ETHER, ... | Authors: | Coronado, M.A, Ullah, A, da Silva, L.S, Chaves-Moreira, D, Vuitika, L, Chaim, O.M, Veiga, S.S, Chahine, J, Murakami, M.T, Arni, R.K. | Deposit date: | 2014-12-01 | Release date: | 2015-06-03 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.72 Å) | Cite: | Structural Insights into Substrate Binding of Brown Spider Venom Class II Phospholipases D. Curr Protein Pept Sci, 16, 2015
|
|